Journal of Agricultural and Food Chemistry最新文献_第2页

Distinct Interaction Tendencies of Resveratrol and Chlorogenic Acid in Starch–Eicosapentaenoic Acid Systems and Their Relationships with Multiscale Structural Organization and Digestion Properties 淀粉-二十碳五烯酸体系中白藜芦醇与绿原酸的明显相互作用趋势及其与多尺度结构组织和消化性质的关系

IF 6.1 1区农林科学

Journal of Agricultural and Food Chemistry Pub Date : 2026-11-09 DOI: 10.1021/acs.jafc.6c07606

Bo Zheng,Hui Wen,Bin Zheng,Zhipeng Qiu,Xingwei Xiang

{"title":"Distinct Interaction Tendencies of Resveratrol and Chlorogenic Acid in Starch–Eicosapentaenoic Acid Systems and Their Relationships with Multiscale Structural Organization and Digestion Properties","authors":"Bo Zheng,Hui Wen,Bin Zheng,Zhipeng Qiu,Xingwei Xiang","doi":"10.1021/acs.jafc.6c07606","DOIUrl":"https://doi.org/10.1021/acs.jafc.6c07606","url":null,"abstract":"Amylose forms inclusion complexes with hydrophobic guests, but how additional bioactives regulate these assemblies through competitive or cooperative interactions remains unclear. Here, starch–unsaturated fatty acid–polyphenol ternary systems were constructed to investigate relationships among molecular interactions, multiscale structures, and digestion properties. Eicosapentaenoic acid (EPA) was associated with V-type amylose ordering consistent with inclusion-complex formation, while the polyphenol-containing systems showed distinct patterns of structural organization. Resveratrol tended to associate with the hydrophobic helical environment, whereas chlorogenic acid showed stronger hydrogen-bond-mediated interaction tendencies around the starch–EPA assembly. Multiscale structural, digestion, and computational analyses revealed distinct associations between polyphenol interaction tendencies and digestion behavior. The RA-containing system showed lower digestibility, suggesting a contribution from structural restriction, whereas the CGA-containing system showed stronger α-amylase inhibition. These findings suggest that polyphenol structure shapes interaction patterns in starch–lipid assemblies and may inform future strategies for modulating starch structure and digestion properties.","PeriodicalId":41,"journal":{"name":"Journal of Agricultural and Food Chemistry","volume":"25 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2026-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149368331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Selenized Sodium Alginate: Characterization and Its Effects on Muscle Nutritional Quality and Flavor Profile under High-Carbohydrate Challenge in Micropterus salmoides 硒化海藻酸钠：表征及其对高碳水化合物刺激下小鱼肌营养品质和风味的影响

IF 6.1 1区农林科学

Journal of Agricultural and Food Chemistry Pub Date : 2026-11-09 DOI: 10.1021/acs.jafc.6c09270

Zhi-Rui Huang,Yi-Ming Xiao,Jia-Rong Wang,Jun-Tong Li,Sheng-Bin Liu,Jia-Min Ma,Lei Zhou,Di-Zhi Xie,Chao Xu

{"title":"Selenized Sodium Alginate: Characterization and Its Effects on Muscle Nutritional Quality and Flavor Profile under High-Carbohydrate Challenge in Micropterus salmoides","authors":"Zhi-Rui Huang,Yi-Ming Xiao,Jia-Rong Wang,Jun-Tong Li,Sheng-Bin Liu,Jia-Min Ma,Lei Zhou,Di-Zhi Xie,Chao Xu","doi":"10.1021/acs.jafc.6c09270","DOIUrl":"https://doi.org/10.1021/acs.jafc.6c09270","url":null,"abstract":"Sodium alginate was selenized via a BaCl2-catalyzed HNO3–Na2SeO3 method to produce selenized sodium alginate (Se-SA). Structural characterization confirmed covalent Se–O–C grafting, spherical nanoparticle formation (∼100 nm), and moderate depolymerization. A 12-week feeding trial with juvenile Micropterus salmoides (∼10 g) compared a high-carbohydrate diet (HC, 20%), HC + 1.0 mg/kg Na2SeO3 (HC-Se), HC + 1.0 mg/kg Se-SA (HC-Se-SA), and HC + 1.0 mg/kg sodium alginate (HC-SA). Dietary Se-SA significantly improved growth performance compared with other dietary treatments. Se-SA was associated with hepatic AMPKα activation and coordinate glycolipid gene regulation, correlating with reduced hepatic steatosis and improved glucose tolerance. Muscle n-3 PUFA content, texture, and antioxidant capacity were enhanced. HS-GC-IMS revealed remodeling of the volatile metabolome toward desirable aroma-active compounds and away from off-odors. These findings support Se-SA as a multifunctional polysaccharide additive for improving flesh quality in carbohydrate-intensive aquaculture.","PeriodicalId":41,"journal":{"name":"Journal of Agricultural and Food Chemistry","volume":"117 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2026-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149368335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of Nematicidal Activity, Structure–Activity Relationship, and Mechanism of C-13-Substituted Berberine Derivatives c -13取代小檗碱衍生物的杀线虫活性、构效关系及机理研究

IF 6.1 1区农林科学

Journal of Agricultural and Food Chemistry Pub Date : 2026-11-09 DOI: 10.1021/acs.jafc.6c11800

Yu-Chen Sun,Yue Zhang,Yan-Ze Wang,Shao-Yong Zhang,Zhi-Jun Zhang,Ya-Ya Lei,Chen-Yang Sang,Bao-Qi Zhang,Ying-Qian Liu

引用次数: 0

Dietary Polystyrene Nanoplastics Exacerbate Valproate-Induced Hepatotoxicity via the Gut–Liver Axis, Involving Microbiota Dysbiosis and Metabolic Disorders 膳食聚苯乙烯纳米塑料通过肠-肝轴加剧丙戊酸诱导的肝毒性，涉及微生物群失调和代谢紊乱

IF 6.1 1区农林科学

Journal of Agricultural and Food Chemistry Pub Date : 2026-11-09 DOI: 10.1021/acs.jafc.6c11059

Dewei Chang,Jianguo Lv,Wenning Shi,Jianwei Gao,Miao Xu,Mengli Han,Yang Wu,Ping Ma,Xu Yang,Yanling Sun

引用次数: 0

Correction to “β-Hydroxybutyric Acid-Induced Bovine Endometrial Epithelial Cell Pyroptosis via Activating P2X7R” 更正“β-羟基丁酸通过激活P2X7R诱导牛子宫内膜上皮细胞热亡”

IF 6.1 1区农林科学

Journal of Agricultural and Food Chemistry Pub Date : 2026-11-09 DOI: 10.1021/acs.jafc.6c15694

Jiajia Mu,Qiannan Sun,Nanyan Lin,Chenguang Yue,Jiaqiao Zhu,Hui Zou,Hongyan Zhao,Ruilong Song,Zongping Liu,Yonggang Ma

引用次数: 0

Variations in the Deposition Behavior, Comprehensive Coloration Performance, and Storage Oxidative Stability of Different Carotenoids in Egg Yolk 不同类胡萝卜素在蛋黄中的沉积行为、综合着色性能和储存氧化稳定性的变化

IF 6.1 1区农林科学

Journal of Agricultural and Food Chemistry Pub Date : 2026-11-09 DOI: 10.1021/acs.jafc.6c07914

Xuanyang Sun,Weichen Huang,Kaijie Zhuang,Yujie Lv,Chaoyue Ge,Ziyu Wang,Lianchi Wu,Xiaoxu Wang,Hongmeng Yuan,Shenao Zhan,Tzuhan Lin,Dongyou Yu,Bing Liu

{"title":"Variations in the Deposition Behavior, Comprehensive Coloration Performance, and Storage Oxidative Stability of Different Carotenoids in Egg Yolk","authors":"Xuanyang Sun,Weichen Huang,Kaijie Zhuang,Yujie Lv,Chaoyue Ge,Ziyu Wang,Lianchi Wu,Xiaoxu Wang,Hongmeng Yuan,Shenao Zhan,Tzuhan Lin,Dongyou Yu,Bing Liu","doi":"10.1021/acs.jafc.6c07914","DOIUrl":"https://doi.org/10.1021/acs.jafc.6c07914","url":null,"abstract":"The color of egg yolk has a significant impact on consumer acceptance, and its main coloring pigment comes from different carotenoids. This study evaluated the deposition and coloration capacity of dietary canthaxanthin, astaxanthin, and lutein in egg yolks, focusing on the oxidative stability of canthaxanthin. While physical parameters remained unaltered, canthaxanthin exhibited the highest coloration capacity, rapidly achieving a maximum color score of 16. Conversely, pigment mixtures yielded lower scores, suggesting visual dilution and competitive interactions, while LC–MS/MS revealed an upper limit on carotenoid deposition. Storage trials demonstrated that canthaxanthin-enriched yolks maintained exceptional color stability and chemical retention over 21 days at 4 °C and 15 °C. Notably, canthaxanthin maintained a consistently lower yolk pH throughout storage and attenuated superoxide dismutase (SOD) depletion. Precise single-pigment supplementation optimizes sensory quality and shelf life, providing practical strategies for laying hen feeding, egg processing, and retail industries.","PeriodicalId":41,"journal":{"name":"Journal of Agricultural and Food Chemistry","volume":"17 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2026-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149368326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ERRFI1 Deficiency Facilitates ErbB1 Hyperphosphorylation to Trigger NLRP3 Inflammasome-Mediated Pyroptosis in Arsenic-Induced Thyroid Injury: In Vivo and In Vitro Evidence ERRFI1缺乏促进ErbB1过度磷酸化触发NLRP3炎症小体介导的砷诱导甲状腺损伤中的焦亡：体内和体外证据

IF 6.1 1区农林科学

Journal of Agricultural and Food Chemistry Pub Date : 2026-11-09 DOI: 10.1021/acs.jafc.6c14320

Lili Fan,Jie Xiang,Qian Song,Huifen Xu,Dapeng Wang

{"title":"ERRFI1 Deficiency Facilitates ErbB1 Hyperphosphorylation to Trigger NLRP3 Inflammasome-Mediated Pyroptosis in Arsenic-Induced Thyroid Injury: In Vivo and In Vitro Evidence","authors":"Lili Fan,Jie Xiang,Qian Song,Huifen Xu,Dapeng Wang","doi":"10.1021/acs.jafc.6c14320","DOIUrl":"https://doi.org/10.1021/acs.jafc.6c14320","url":null,"abstract":"Arsenicals are widespread endocrine-disrupting contaminants in agricultural environments and food supplies. Our prior work has linked arsenic exposure to thyroid cell pyroptosis and consequent tissue injury, yet the underlying molecular mechanism remains unclear. This study interrogated the ERRFI1-ErbB1/ERK axis mediating sodium arsenite (NaAsO2)-induced thyroid injury using in vivo SD rat models and in vitro Nthy-ori 3–1 cells. In rats, NaAsO2 decreased ERRFI1, boosted ErbB1/ERK phosphorylation, and caused thyroid injury and endocrine dysfunction; these adverse effects were partially reversed by the ErbB1 inhibitor erlotinib. In Nthy-ori 3–1 cells, NaAsO2 elicited NLRP3 inflammasome-dependent pyroptosis, repressed ERRFI1, hyperactivated ErbB1/ERK signaling. Pharmacological bidirectional modulation of ErbB1 confirmed its critical role, while ERRFI1 overexpression dampened ErbB1/ERK phosphorylation and mitigated pyroptosis. Collectively, NaAsO2 represses ERRFI1 to hyperactivate ErbB1/ERK, triggering NLRP3 inflammasome-mediated thyroid cell pyroptosis and endocrine dysfunction. These findings define a novel mechanism of arsenic thyrotoxicity and identify the ERRFI1-ErbB1/ERK axis as a promising intervention target.","PeriodicalId":41,"journal":{"name":"Journal of Agricultural and Food Chemistry","volume":"281 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2026-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149368323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Peptidomics Reveals That Goat Milk Is Closer to Human Milk Than Cow Milk in Proline-Rich Oligopeptide Release during In Vitro Dynamic Infant Digestion 肽组学揭示羊奶在体外动态婴儿消化过程中富含脯氨酸的寡肽释放比牛奶更接近人乳

IF 6.1 1区农林科学

Journal of Agricultural and Food Chemistry Pub Date : 2026-11-09 DOI: 10.1021/acs.jafc.6c09524

Hailing Song,Yifei Li,Caidong Zhao,Zeyuan Deng,Xiaoyu Peng,Wei Li,Yu Gao,Yalun Zou,Liufeng Zheng

{"title":"Peptidomics Reveals That Goat Milk Is Closer to Human Milk Than Cow Milk in Proline-Rich Oligopeptide Release during In Vitro Dynamic Infant Digestion","authors":"Hailing Song,Yifei Li,Caidong Zhao,Zeyuan Deng,Xiaoyu Peng,Wei Li,Yu Gao,Yalun Zou,Liufeng Zheng","doi":"10.1021/acs.jafc.6c09524","DOIUrl":"https://doi.org/10.1021/acs.jafc.6c09524","url":null,"abstract":"Human milk is the gold standard for infant nutrition. This study employed an in vitro dynamic infant gastrointestinal digestion model coupled with peptidomics to profile oligopeptide release from human, goat, and cow milk. Peptidomics identified 717, 658, and 514 oligopeptides from human, goat, and cow milk, respectively. Goat milk closely mirrored human milk in length distribution, with both peaking at 4–5 residues, whereas cow milk exhibited a peak at 6–7 residues. Proline was the most abundant amino acid residue across all sources, and goat milk generated significantly higher numbers of short oligopeptides (≤10 residues) than cow milk. Notably, 38 oligopeptides were exclusively shared between human and goat milk, predominantly proline-rich, casein-derived sequences with multiple predicted bioactivities. These findings indicate that goat milk is predicted to offer functional advantages over cow milk for human milk-oriented infant nutrition, primarily through its capacity to generate proline-rich bioactive oligopeptides.","PeriodicalId":41,"journal":{"name":"Journal of Agricultural and Food Chemistry","volume":"260 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2026-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149368325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Human Milk-Derived Synbiotics Attenuate DSS-Induced Colitis in Mice via Promoting Intestinal Colonization of Lachnospira 人乳衍生合生剂通过促进毛螺旋体的肠道定植来减轻dss诱导的小鼠结肠炎

IF 6.1 1区农林科学

Journal of Agricultural and Food Chemistry Pub Date : 2026-11-09 DOI: 10.1021/acs.jafc.6c10263

Xiaomeng Wang,Yuxuan Ma,Guodong Zhang,Hong Jiang,Jianan Sun,Xiangzhao Mao

{"title":"Human Milk-Derived Synbiotics Attenuate DSS-Induced Colitis in Mice via Promoting Intestinal Colonization of Lachnospira","authors":"Xiaomeng Wang,Yuxuan Ma,Guodong Zhang,Hong Jiang,Jianan Sun,Xiangzhao Mao","doi":"10.1021/acs.jafc.6c10263","DOIUrl":"https://doi.org/10.1021/acs.jafc.6c10263","url":null,"abstract":"2′-Fucosyllactose (2′-FL) exhibits prebiotic properties, but its ability to enhance probiotic efficacy in ulcerative colitis (UC) is incompletely understood. Here, we show that 2′-FL effectively enhances the protective effect of Bifidobacterium bifidum B-67 against DSS-induced colitis in mice. Combination therapy outperformed individual treatments, suppressing pro-inflammatory cytokines and restoring mucosal integrity. Mechanistically, 2′-FL remodeled the gut microbiota, enriched butyrate-producing Lachnospira, promoted SCFA production, and upregulated epithelial adhesion molecules HAS1 and GPC-1, which are associated with enhanced Lachnospira adhesion. In vitro coculture further indicated that B. bifidum B-67 acts as the primary degrader of 2′-FL and supports Lachnospira growth, suggesting a cross-feeding effect. Untargeted metabolomics revealed distinct metabolic alterations, including in bile acid-related pathways, associated with the combination intervention. These findings indicate that 2′-FL potentiates B. bifidum via both metabolic cross-feeding and enhanced bacterial retention, supporting this synbiotic combination as a promising strategy for UC intervention.","PeriodicalId":41,"journal":{"name":"Journal of Agricultural and Food Chemistry","volume":"12 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2026-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149368328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conformational and Rheological Changes of Hericium erinaceus Polysaccharides Driven by Molecular Weight Reduction and Their Impact on Prebiotic Effects 猴头菌多糖分子量降低导致的构象和流变学变化及其对益生元效应的影响

IF 6.1 1区农林科学

Journal of Agricultural and Food Chemistry Pub Date : 2026-11-09 DOI: 10.1021/acs.jafc.6c11025

Qiang Yu,Mingxiao Cui,Di Wu,Wen Li,Wanchao Chen,Peng Liu,Zhong Zhang,Yan Yang

{"title":"Conformational and Rheological Changes of Hericium erinaceus Polysaccharides Driven by Molecular Weight Reduction and Their Impact on Prebiotic Effects","authors":"Qiang Yu,Mingxiao Cui,Di Wu,Wen Li,Wanchao Chen,Peng Liu,Zhong Zhang,Yan Yang","doi":"10.1021/acs.jafc.6c11025","DOIUrl":"https://doi.org/10.1021/acs.jafc.6c11025","url":null,"abstract":"Hericium erinaceus polysaccharide was degraded using microwave-assisted enzymatic hydrolysis to obtain four gradient molecular weight fractions (HePs). This study investigated the effects of molecular weight on their structural, rheological, and prebiotic properties. The reduction in molecular weight preserved the monosaccharide composition, functional groups, and residue types but significantly decreased their apparent viscosity and converted spatial conformations from compact and rigid triple-helix structures into flexible random coils. All HePs resisted in vitro gastrointestinal digestion and were utilized by gut microbiota. HePs increased the relative abundance of short-chain fatty acid-producing bacteria such as Megamonas, Megasphaera, Bifidobacterium, and Ligilactobacillus. The upregulation effects of HePs on the above intestinal microbiota and short-chain fatty acids were negatively correlated with molecular weight. Molecular weight may affect the modulatory effects of HePs on the dominant intestinal microbiota, functional enzyme expression, and microbial metabolic pathways. These findings may provide a research basis for the development of HePs prebiotic products.","PeriodicalId":41,"journal":{"name":"Journal of Agricultural and Food Chemistry","volume":"9 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2026-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149368330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0