European Oral Research最新文献

{"title":"Development, validity, and reliability of the band and loop radiographic assessment scoring system (BRASS).","authors":"Deepika Chari, Anup Panda, Balraj Shukla","doi":"10.26650/eor.20251574047","DOIUrl":"10.26650/eor.20251574047","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to develop a radiographic evaluation scale which, when combined with clinical criteria, could help reduce the failure rate of the conventional band and loop (CBL) space maintainer.</p><p><strong>Materials and methods: </strong>The Band and Loop Radiographic Assessment Scoring System (BRASS) was developed following best practices for scale development in healthcare. The process began with data collection through a literature review, followed by face and content validity assessment of the items generated using the sum-score decision rule and content validity ratio. Pre-testing of the scale was conducted through item-total correlation and factor analysis using the Tucker-Lewis Index, which facilitated item reduction. Pilot testing of the scale was subsequently carried out, and test-retest reliability, predictive validity, and two measures of construct validity were evaluated.</p><p><strong>Results: </strong>The initial pool of 20 items was reduced to 10, distributed across three criteria based on the results of the goodness-of-fit test. The mean accuracy of the scale, based on predictive validity, was 89%. Test-retest reliability, measured by Cronbach's Alpha, was 0.87. Construct validity revealed a significant difference (p less than 0.05) in evaluations conducted with and without the use of BRASS. Finally, multiple linear regression analysis indicated a strong model fit (R-squared = 0.991), further supporting the construct validity of the BRASS.</p><p><strong>Conclusion: </strong>The development of BRASS, supported by strong validity and reliability metrics, presents it as a promising tool to enhance the clinical success of the conventional band and loop (CBL) space maintainer.</p>","PeriodicalId":41993,"journal":{"name":"European Oral Research","volume":"60 1","pages":"71-78"},"PeriodicalIF":1.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12882791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146144221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro evaluation of antimicrobial and cytotoxic activity of newly synthesized and characterized nanocurcumin.","authors":"Anila S, Aldrin Antony, Dhanya P Jacob, Ambili Renjith","doi":"10.26650/eor.20251576613","DOIUrl":"10.26650/eor.20251576613","url":null,"abstract":"<p><strong>Purpose: </strong>Curcumin, the principal curcuminoid found in turmeric, demonstrates potent antibacterial and anti-inflammatory characteristics; nevertheless, it possesses restricted solubility and bioavailability. Numerous studies have reported elevated bioavailability and antimicrobial activity of nano-formulations of curcumin. Porphyromonas gingivalis plays a crucial role in triggering dysbiosis in the subgingival milieu, leading to the progression of periodontitis. This work details nanocurcumin preparation, characterization, and in vitro evaluation of antibacterial activity against Porphyromonas gingivalis and its cytotoxic effects on L929 mouse embryo fibroblasts.</p><p><strong>Materials and methods: </strong>Nanocurcumin was prepared using the antisolvent precipitation method and characterized by Scanning electron microscopy, UV-visible spectrophotometry, Fourier transform infrared spectroscopy, and Nuclear Magnetic Resonance. The antimicrobial activity of nanocurcumin against Porphyromonas gingivalis was assessed using the minimum inhibitory concentration (MIC). Cytotoxicity against L929 mouse embryo fibroblasts was evaluated with the MTT assay.</p><p><strong>Results: </strong>Nanocurcumin exhibited significant water solubility, nanoparticle size ranging from 18 to 176 nm, a strong absorbance peak at 425nm, and a comparable chemical structure to curcumin. MIC of nanocurcumin was 6.25 µg/ml compared to 25 µg/ml of curcumin and 3.12 µg/ml of tetracycline. Both nanocurcumin and curcumin demonstrated a dose-dependent negative impact on L929 fibroblasts with IC50 concentrations of 86.16 µg/ml and 45.69 µg/ml respectively.</p><p><strong>Conclusion: </strong>Nanocurcumin in the present study demonstrates well-characterized nanoparticle formation with excellent antimicrobial activity against Porphyromonas gingivalis and minimal cytotoxicity against L929 cell line. Nanocurcumin demonstrates significant promise for integration into drug delivery systems for the management of periodontal disease, subject to additional experimental and clinical trials.</p>","PeriodicalId":41993,"journal":{"name":"European Oral Research","volume":"60 1","pages":"45-51"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12880739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146144213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retreatability of guttaflow bioseal in bulk or with main cone from root canals using ultrasonic, laser, and xp-endo finisher activated techniques.","authors":"Esin Özlek, Gizem Kadı, Hüseyin Gündüz, Yousef Saed","doi":"10.26650/eor.20251536018","DOIUrl":"10.26650/eor.20251536018","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to investigate the efficacy of ultrasonic, laser, and XP-Endo Finisher activation techniques for the removal of GuttaFlow Bioseal from root canals.</p><p><strong>Materials and methods: </strong>In this study, 64 extracted mandibular premolar teeth were instrumented using ProTaper Next files up to size X3 and randomly divided into two groups (n = 32) based on the obturation method: Group 1 - GuttaFlow Bioseal with gutta-percha, and Group 2 - GuttaFlow Bioseal without gutta-percha. After root filling removal, the specimens were randomly allocated into one of four activation subgroups (n = 8): Subgroup A - Conventional Needle Irrigation; Subgroup B - Passive Ultrasonic Activation; Subgroup C - XP-Endo Finisher; and Subgroup D - Er, Cr: YSGG Laser. The teeth were then sectioned longitudinally, and photographic images were captured under a stereomicroscope. Residual filling materials in the coronal, middle, and apical thirds were measured using ImageJ software. Data were statistically analyzed with three-way ANOVA and Tukey's HSD test (p less than 0.05).</p><p><strong>Results: </strong>The lowest amount of residual filling material was observed in the Er, Cr: YSGG laser group, followed by the XP-Endo Finisher, passive ultrasonic activation, and conventional needle irrigation groups, respectively (p less than 0.001). There was no statistically significant difference in retreatability between GuttaFlow Bioseal used with or without gutta-percha (p = 0.754).</p><p><strong>Conclusion: </strong>This study demonstrates that different activation techniques significantly improve the removal of GuttaFlow Bioseal from root canals; however, none achieved complete removal. Among the tested methods, the Er, Cr: YSGG laser was the most effective, followed by the XP-Endo Finisher and passive ultrasonic activation. These results suggest that the Er, Cr: YSGG laser is a highly effective option for endodontic retreatment.</p>","PeriodicalId":41993,"journal":{"name":"European Oral Research","volume":"60 1","pages":"79-85"},"PeriodicalIF":1.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12883030/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146150887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of pH on the mechanical properties of beta titanium orthodontic arch wires.","authors":"Jillian Huffman, Andrew G Chapple, Paul Armbruster, Richard Ballard, Sarah Dawson, Harrison Rosen, Xiaoming Xu","doi":"10.26650/eor.20251621662","DOIUrl":"10.26650/eor.20251621662","url":null,"abstract":"<p><strong>Purpose: </strong>This study sought to compare mechanical properties of beta titanium orthodontic wires to stainless steel and NiTi archwires under different pH conditions and for different time intervals.</p><p><strong>Materials and methods: </strong>Twenty samples of 5 different orthodontic arch wires were submerged in buffer solutions with pH 4.0, 5.5, and 7.0 for 6 and 18 weeks. Tensile and flexural strength tests were performed. 2-factor ANOVA was performed for the pH/time combinations and the 5 different arch wires. Wald-based tests were performed to determine if the change rate of the wires differed significantly from the others.</p><p><strong>Results: </strong>Two beta titanium wires at pH 4.0 exhibited significantly lower flexural strength at 6 weeks (T1) but difference diminished at 18 weeks (T2). pH value did not impact the flexural strength of NiTi and SS wires. There was no trend in the flexural strength of any wires in any pH solution from T0-T1 but there was significant decrease in strength for all wires from T0-T2. There was no trend in the change in tensile strength of the beta titanium wires and NiTi wires across any pH or time interval. There was a significant increase in the tensile strength of stainless-steel wires over all pH environments and time points.</p><p><strong>Conclusion: </strong>There was a significant decrease in flexural strength of all wires over time and beta titanium archwires decreases significantly more than NiTi and SS wires. There is no significant change in tensile strength of beta titanium and NiTi wires over time. Tensile strength of stainless-steel wires increased significantly over time.</p>","PeriodicalId":41993,"journal":{"name":"European Oral Research","volume":"60 1","pages":"86-91"},"PeriodicalIF":1.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12883069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146150940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of demineralization changes utilizing the Canary Caries Detection System and various toothpastes on incipient enamel lesions.","authors":"Skylar Steel, Htwe Mon, Xiaoming Xu, Andrew G Chapple, Hope Grandy, Richard Ballard, Paul Armbruster","doi":"10.26650/eor.20251568648","DOIUrl":"10.26650/eor.20251568648","url":null,"abstract":"<p><strong>Purpose: </strong>The Canary Caries Detection System has been shown to quantify the degree of demineralization of incipient enamel. The objective of this study was to evaluate and compare demineralization changes after applying various toothpastes on incipient enamel lesions utilizing the Canary Caries Detection System.</p><p><strong>Materials and methods: </strong>Thirty-five extracted human teeth premolars were divided into seven groups (n=5). Each group was demineralized in a lactate acid buffer solution (pH 4.5) and tested using one of six toothpastes or a phosphate buffer solution (control, pH 7.4). The teeth were brushed according to manufacturer's instructions daily for 28 days. Canary Numbers, standardized cold light, and fluorescent photographs were collected at the initial (T0), following demineralization (T1), day 14 (T2), and day 28 (T3).</p><p><strong>Results: </strong>It was found that there was a statistical difference between all groups and the control between T2-T3 (p<0.046 facial surfaces) and T1-T3 (p<0.015 lingual surfaces). There was also a statistical difference between T1-T3 when comparing all groups. The cold light and fluorescent light photos also show evidence of changes in demineralization from T1-T3 in the PreviDent 5000 Plus group.</p><p><strong>Conclusion: </strong>The PreviDent 5000 Plus group demonstrated a statistical difference to Clinpro 5000, MI Paste Plus and PreviDent 5000 Booster Plus from T1-T3 as the Canary Numbers decreased. There was an increase and significant difference in the PBS group Canary Numbers from T1-T3, indicating the negative control showed continued demineralization.</p>","PeriodicalId":41993,"journal":{"name":"European Oral Research","volume":"60 1","pages":"98-104"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12954878/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does the chin projection and sella point position affect the W angle reliability?","authors":"Meryem Akpınar, Farhad Salmanpour, Hasan Camcı","doi":"10.26650/eor.20251558329","DOIUrl":"10.26650/eor.20251558329","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to compare the reliability and validity of the Sella (S) and G points used in the W angle for different types of malocclusions.</p><p><strong>Materials and methods: </strong>Pretreatment cephalometric radiographs of 700 individuals aged 15 to 25 years, who began orthodontic treatment between 2019 and 2024, were randomly selected from the archives of the Department of Orthodontics at Afyonkarahisar Health Sciences University. After applying exclusion criteria, 570 radiographs (290 females, 280 males) were included in the study. These radiographs were divided into three groups based on ANB and Wits values: Class I (C1) (n = 103), Class II (C2) (n = 178), and Class III (C3) (n = 111). Each group was further divided into nine subgroups according to chin projection (low [a1], normal [a2], high [a3]), the vertical position of the sella point (low [b1], normal [b2], high [b3]), and the sagittal position of the sella point (low [c1], normal [c2], high [c3]). The vertical position of the sella point was determined by calculating its distance from the FH plane, while its sagittal position was assessed by measuring the distance of its projection onto the FH plane relative to the orbitale point. Chin projection was determined using the Pg-NB measurement.</p><p><strong>Results: </strong>Statistical analysis showed that chin projection was positively correlated with the W angle in all subgroups (p < 0.001). The sagittal position of the sella point did not significantly affect the W angle in any of the classes. However, the vertical position of the sella point was positively correlated with the W angle only in the subgroups with high vertical values (C1b3, p = 0.002; C2b3, p < 0.001; C3b3, p < 0.001).</p><p><strong>Conclusion: </strong>Both chin projection and the vertical position of the sella point were found to influence the W angle, whereas the sagittal position of the sella point did not have a significant effect.</p>","PeriodicalId":41993,"journal":{"name":"European Oral Research","volume":"60 1","pages":"105-112"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12954877/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Marginal microleakage at the adhesive bonding interface submitted to storage in water, chemical aging or thermocycling.","authors":"Pedro Ivo da Graça Fagundes, Ricardo Armini Caldas, Rafael Leonardo Xediek Consani","doi":"10.26650/eor.20251440402","DOIUrl":"10.26650/eor.20251440402","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this in vitro study was to evaluate the marginal microleakage of the dentin/resin interface when subjected to water storage, chemical aging, or thermocycling in different adhesive luting treatments.</p><p><strong>Materials and methods: </strong>Bovine teeth were used to prepare dentin blocks (5 × 4 × 1 mm) with one fully exposed dentin surface (n = 45). The blocks were randomly assigned to three luting protocols: 2BSE+DRC (two-bottle self-etch adhesive + dual-curing resin cement); SAP+PRC (self-adhesive primer + photo-activated dual resin cement); and SAP+SRC+O (self-adhesive primer + self-cured dual resin cement + Oxyguard II). Composite resin blocks of the same dimensions were luted onto the dentin blocks according to each protocol. Each treatment group (n = 15) was subdivided into three subgroups (n = 5) based on the aging challenge: storage in water for 7 days (control), aging in 10% sodium hypochlorite solution for 1 hour, or thermocycling for 5,000 cycles. Specimens were then individually immersed in a neutral methylene blue solution for 1 hour, rinsed with water, air-dried, and analyzed for marginal microleakage.</p><p><strong>Results: </strong>Data analyzed by ANOVA and Tukey's test (α = 0.05) showed that 2BSE+DRC exhibited the lowest microleakage after water storage for 7 days (100µm) and the highest after thermocycling (220µm), while sodium hypochlorite aging resulted in an intermediate value (190µm). SAP+PRC and SAP+SRC+O showed no statistically significant differences in microleakage when stored in water (170µm and 620µm, respectively) or after sodium hypochlorite aging (180µm and 610µm, respectively). SAP+SRC+O resulted in significantly greater microleakage in water storage (620µm) and sodium hypochlorite aging (610µm) compared to 2BSE+DRC (100µm and 190µm, respectively) and SAP+PRC (170µm and 180µm, respectively). Thermocycling produced significant differences among the three treatments (p less than 0.05), with SAP+SRC+O showing the highest microleakage (1,370µm), 2BSE+DRC the lowest (220µm), and SAP+PRC an intermediate value (810µm).</p><p><strong>Conclusion: </strong>Adhesive luting treatments exhibited different levels of marginal microleakage when subjected to water storage, chemical aging, or thermocycling. Thermocycling resulted in the highest marginal microleakage at the dentin/resin interface for all adhesive protocols tested.</p>","PeriodicalId":41993,"journal":{"name":"European Oral Research","volume":"60 1","pages":"65-70"},"PeriodicalIF":1.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12882784/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146143356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality assessment of different root canal obturation techniques in 3D printed teeth with varied ısthmus sizes: a phantom study.","authors":"Sebahat Aygörmez, Ali Keleş, Cangül Keskin","doi":"10.26650/eor.20251599733","DOIUrl":"10.26650/eor.20251599733","url":null,"abstract":"<p><strong>Purpose: </strong>This study compared the quality of different filling techniques with two different sizes of isthmuses.</p><p><strong>Materials and methods: </strong>Specimens were produced with a 3D printer (EnvisionTEC Vida, Gladbeck, Germany) and allocated into groups (n=10): Group 1; narrow isthmus with cold lateral compaction (CLC), Group 2; narrow isthmus with warm vertical compaction (WVC), Group 3; wide isthmus with CLC, and Group 4; wide isthmus with WVC. The specimens were sectioned at 4 mm and 8 mm from the apex, and the filling materials and voids in the isthmuses were assessed using ImageJ software (National Institutes of Health, Bethesda, MD, USA).</p><p><strong>Results: </strong>None of the techniques produced void-free fillings. In wide isthmuses, warm vertical compaction (WVC) resulted in significantly greater total void percentages (10.39 ± 8.23%) compared to cold lateral compaction (CLC) (1.30 ± 2.90%) (p = 0.000). In narrow isthmuses, both techniques produced similar void percentages (WVC: 3.33 ± 4.91%, CLC: 1.19 ± 2.67%) (p > 0.05). In the coronal portion of the wide isthmus, the amount of gutta-percha was significantly greater in WVC (p = 0.032), whereas in the apical portion, the sealer percentage was significantly higher in the CLC group. Similarly, in the narrow isthmus groups, the apical sealer percentage was greater in the CLC group (p = 0.000).</p><p><strong>Conclusion: </strong>Both CLC and WVC failed to produce void-free canal fillings in band-shaped isthmuses. WVC showed a higher total void percentage in wide isthmuses, whereas both techniques had similar void percentages in narrow isthmuses.</p>","PeriodicalId":41993,"journal":{"name":"European Oral Research","volume":"60 1","pages":"52-58"},"PeriodicalIF":1.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12880804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146143859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A quasi-experimental study comparing the effectiveness of lecture-based and drama teaching methods on oral health outcomes in students with intellectual disabilities.","authors":"Reza Emrani, Mahnaz Pouresmaeil, Rahimi Khalifehkandi","doi":"10.26650/eor.20251619290","DOIUrl":"10.26650/eor.20251619290","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the effectiveness of a school-based program designed for children with mental disabilities by assessing oral health outcomes after training via two educational methods: lectures and dramas.</p><p><strong>Materials and methods: </strong>144 male students with mental disabilities from a special needs school in Qazvin, Iran, were selected as a census sample in 2023. The students were randomly divided into two groups, each consisting of 72 participants aged 10-14 years. Group 1 received oral health counseling via the lecture method, whereas Group 2 was instructed via the drama method. Data were collected via a socio-demographic checklist, and oral health was assessed via the Decayed, Missing, and Filled Teeth (DMFT) Index for caries status and the Simplified Oral Hygiene Index (OHI-S) of Greene and Vermillion for oral hygiene. Assessments were conducted before and four weeks after the intervention. Data analysis was performed via descriptive statistics, t tests, and ANOVA via SPSS software.</p><p><strong>Results: </strong>A statistically significant improvement in plaque scores was observed in the Drama group compared with the Lecture group after the intervention (p less than 0.05). The mean tooth filling index (F index) also increased significantly in both groups post intervention, with greater improvement noted in the Drama group. While oral health indices improved in both groups, the extent of improvement was significantly greater in the Drama group.</p><p><strong>Conclusion: </strong>The drama method used in this study was more effective than the lecture method in improving participants' oral and dental health indices. As a simple and cost-effective approach, drama enables teachers to convey essential health information more effectively.</p>","PeriodicalId":41993,"journal":{"name":"European Oral Research","volume":"60 1","pages":"59-64"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12881908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146144211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does platelet-rich fibrin improve the clinical outcomes of intentional replantation in the treatment of periodontally hopeless teeth?","authors":"Hanife Merva Parlak, Ayhan Parmaksiz, Ozgur Uyanık, Onurcem Duruel, H Gencay Keceli","doi":"10.26650/eor.20251561000","DOIUrl":"10.26650/eor.20251561000","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to evaluate the impact of using platelet-rich fibrin (PRF) on clinical parameters in intentional replantation (IR) treatment.</p><p><strong>Materials and methods: </strong>Data were obtained from 32 mandibular anterior teeth with a 15-month follow-up, treated with either IR (n=17) or IR+PRF (n=15). Periodontal parameters included probing depth (PD), clinical attachment level (CAL), plaque index (PI), gingival index (GI), and keratinized tissue height (KTH), all of which were assessed retrospectively.</p><p><strong>Results: </strong>PD reduction at mesial and midlingual sites was greater in the IR+PRF group at the 15-month follow-up (p=0.043 and p=0.017, respectively), whereas CAL gain in the IR+PRF group was significantly higher at 3, 6, and 15 months (p less than 0.05). GI scores were similar in both groups, while PI scores were higher in the IR group at 6 and 15 months (p less than 0.05). Changes in KTH were similar in both groups at all follow-up periods.</p><p><strong>Conclusion: </strong>IR can be considered for the treatment of periodontally hopeless mandibular anterior teeth, and combining IR with PRF may improve clinical outcomes. However, its clinical use should be recommended cautiously due to the lack of histological data regarding the effects of PRF on IR healing.</p>","PeriodicalId":41993,"journal":{"name":"European Oral Research","volume":"60 1","pages":"11-17"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12880599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146144233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}