Perinatology and reproductology: from research to practice最新文献

{"title":"Women have prognostication of gestational complications with a high perinatal risk","authors":"Serhij Vdovichenko, Serhij Sal’nikov","doi":"10.52705/2788-6190-2022-03-3","DOIUrl":"https://doi.org/10.52705/2788-6190-2022-03-3","url":null,"abstract":"The objective: is an increase of efficiency of prognostication of complications of gestation forwomen with a high perinatal risk on the basis of the use of modern informing markers.\u0000\u0000Materials and methods. Researches carried stage-by-stage character: on I the stage 150women were inspected with the different degree of perinatal risk; on the II stage – 50 women withcomplications at previous pregnancy. In the complex of the conducted researches were includedclinical, echographic, doppler, cariotocographic, laboratory.\u0000\u0000Results. The ball measuring system of estimation of risk of gestational complications is offeredallows to ground expedience of conducting of medical measures in the group of risk. At the sametime the presented approach opens the prospect of selection to the contingent of pregnant,treatment-and-prophylactic measures, which do not need leadthrough which will allow to avoidgroundless interferences with a gestational process.\u0000\u0000Conclusion. The use of the offered method of prognostication will allow to reduce frequency ofcomplications of pregnancy.","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116136440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of organ­preserving operations on ovaries on the menstrual function of women","authors":"","doi":"10.52705/2788-6190-2022-03-6","DOIUrl":"https://doi.org/10.52705/2788-6190-2022-03-6","url":null,"abstract":"Frequency of violations of menstrual function for women after operations on ovaries is conditionedby both violations to the operation and consequence of operative interference. High percent ofchanges of menstrual cycle to the operation (46,0% – with mature teratoma and 54,0% withoutage of serosal cystadenoma), in obedience to our information, direct proportion correlates withthe level of change of ovarian reserve.In a postoperative period the increase of number of patients is marked with violation of menstrualfunction in 1,3–1,4 time in a greater degree after the resection of ovary. Shortening of cycle andoligomenorrhea prevailed among all types of violations of menstrual cycle.Findings must be taken into account at development of algorithm of diagnostic, treatment-andprophylacticand rehabilitation measures.","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116465499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Home / Archives / Vol. 2 No. 3 (2022): Perinatology and reproductology: from research to practice / Articles\u0000Patients have tactic of auxiliary genesial technologies after the different methods of operative treatment of pathology of cervix","authors":"I. Kostyuk","doi":"10.52705/2788-6190-2022-03-9","DOIUrl":"https://doi.org/10.52705/2788-6190-2022-03-9","url":null,"abstract":"The objective: is proceeding in a genesial function for women after the different methods ofoperative treatment of pathology of cervix on the basis of study for them clinical—and-functionaland morphological features, and also improvement and introduction of algorithm of surgical andtreatment-and-prophylactic measures with the use of auxiliary genesial technologies.\u0000\u0000Materials and methods. An inspection and treatment was conducted 96 patients of genesial agewith infertility on a background passionately dystrophic and hyperplastic processes of endocervix.Basic group from 70 patients were made by women, which treatment of pathology of cervix whichwas studied was executed, by the methods of cryolysis or radio wave surgery (in particular by themethod of cryolysis – 30 patients, by the method of radio wave surgery – 40 patients); to the groupcomparisons entered 26 women which surgical operations – curettage and bougienage concerningpathology of cervix were executed.\u0000\u0000Results. Pathology of cervix is one of principal reasons of femaly infertility, thus in 45,8% – primaryand in 54,2% – secondary. Concomitant violations of menstrual function for these patients meet in89,6%, and chronic inflammatory processes of uterus and appendages – in 33,4% respectively. Forwomen with the secondary infertility after the different methods of operative treatment of pathologyof cervix the burdened genesial anamnesis takes place due to high-purity of artificial (73,7%)and involuntary abortions (44,7%), thus a level of inflammatory complications after differentendometrial interferences is 86,4%. The clinical results of auxiliary genesial technologies dependon the presence of concomitant dishormonal violations for women after the different methods ofoperative treatment of pathology of cervix: frequency of implantation – higher at 1,7 time, offensiveof pregnancy – in 2,0 times and births by a living fetus – at 2,1 time.\u0000\u0000Conclusions. The got results testify to efficiency of the offered algorithm of the differentiated goingnear the introduction of auxiliary genesial technologies for women with pathology of cervix takinginto account the presence of concomitant dishormonal violations. The presented information allowto recommend the improved algorithm for the wide use in cabinets and clinics of reprooduction.","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129121376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Placental disfunction for women with retrochorial haematomas in I trimester of pregnancy: diagnostics and management tactics","authors":"I. Koshova","doi":"10.52705/2788-6190-2022-03-2","DOIUrl":"https://doi.org/10.52705/2788-6190-2022-03-2","url":null,"abstract":"The objective: is a decline of frequency of placenta disfunction and perinatal pathology forwomen with the different forms of retrochorial haematomas on the basis of study clinical-andinstrumentaland laboratory researches, and also improvement of algorithm of diagnostic andtreatment-and-prophylactic measures.\u0000\u0000Materials and methods. In research which was conducted in 2 stages, it was included 140pregnant in terms from 6 weeks of гестації and to delivery. On a 1 stage by us 3 groupsof women were selected, on the basis of results of clinical inspection and information ofultrasonic research : 60 pregnant of woman with a recurrent retrochorial haematoma (1group); 50 pregnant with a retrochorial haematoma, which appeared only on the early termsof pregnancy (6–12 weeks inclusive) (2 groups) and 30 the prospectively inspected patientswith uncomplicated pregnancy, which do not have meaningful extragenital pathology andburdened factors obstetric-gynaecological to anamnesis (control group). On 2 stages from60 pregnant with a recurrent retrochorial haematoma by us two sub-groups were selected:1.1 and 1.2.To the sub-group 1.1 30 women were included in the terms of gestation 20-40 weeks,pregnancy in which was conducted on the basis of findings complex clinical-and-laboratoryand echographic inspection, with application of approach which personalize, depending onthat which prevails and etiopathogenetic co-factors with obligatory registration of the writteninformed consent of patients. Sub-group 1.2 were 30 pregnant with the relapse of retrochorialhaematoma, also inspected in obedience to a mine-out design with application of all methods, but pregnancy in which was conducted in obedience to recommendations of MOZ of Ukraine.\u0000\u0000Results. Frequency of placenta disfunction at a recurrent retrochorial haematoma is 70,0%; atprimary – 30,0%; a level of early forms (to 32 weeks) of delay of development of fetus is 65,0% with the considerable level of II-III of degree – 23,3%. The premature ripening of placenta ata recurrent retrochorial haematoma is 33,3%; at primary – 16,0%. Echo-sign of mesenchymaldysplasia and heterogeneity placenta according to 11,7% and 4,0%.At a recurrent retrochorial haematoma frequency of shortage of water is 16,7% against 4,0%– at primary; violations of blood stream are diagnosed in 23,3% and 6,0%; in the structureof all violations of blood stream in 63,3% – make in an uterine artery and in 30,0% – it isconnected with violation of umbilical cord blood stream. In 5,0% only at a recurrent retrochorialhaematoma there is decompensated placenta disfunction with development of acute fetaldistress.\u0000\u0000Conclusions. The use of the algorithm of diagnostic and treatment-and-prophylactic measuresimproved by us allows to reduce frequency of relapse of retrochorial haematoma at 4,7 time; itlarge volume – at 3,9 time; level of premature births – in 2 times; frequency of placenta disfunctionand delay of development of fetus – at 6,5 time, to decrease perinatal lo","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"118 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132434798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Features of sexual conduct of girls are with different motion of puberty","authors":"Orysya Kovalishin","doi":"10.52705/2788-6190-2022-03-5","DOIUrl":"https://doi.org/10.52705/2788-6190-2022-03-5","url":null,"abstract":"The objective: to conduct the estimation of sexual conduct of girls-teenagers with differentmotion of puberty.\u0000\u0000Materials and methods. The perspective inspection of 94 patients which appealed for a help ina medical clinic «Alternative» c. Lviv. All girls were up-diffused on five groups – 1 - 15 girls by age14 years; 2 – 19 girls by age 15 years and 3 – 24 girls by age 16 years: 4 – 18 girls by age 17years; 5 – 18 girls by age 18 years.\u0000\u0000Results. From 94 inspected girls-teenagers 10 teenagers had a weak type of sexual constitution,that was 10,9%, a middle type is 64 teenagers, that was 68%, and 20 girls-teenagers hada strong type of sexual constitution, that was 21,2%. The results of this research lead tocircumstance that sexual activity of girls-teenagers depends not only on the rates of the sexualripening (hormonal background) but also from other, individual features of development of everyteenager, on forming of which such factors can influence as: congenital psychotype, sociumand family. Findings will help us in the subsequent study of questions which touch the sexualconduct of girls-teenagers and influence of sexual activity on development of such seriouspathology as violation of menstrual function.\u0000\u0000Conclusion. The got results testify to the necessity of account of features of sexual conductof girls-teenagers with a different somatotype for development of algorithm of prophylaxis ofviolations of menstrual function.","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131856563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Women have a prophylaxis of unmaturing of pregnancy with the underweight","authors":"O.O. Bozhenko","doi":"10.52705/2788-6190-2022-03-1","DOIUrl":"https://doi.org/10.52705/2788-6190-2022-03-1","url":null,"abstract":"The objective: а research purpose is a decline of frequency of unmaturing of pregnancy for womenwith the underweight on the basis of study of clinical-and-echographic and biochemical features,and also improvement of algorithm of diagnostic and treatment-and-prophylactic measures.\u0000\u0000Materials and methods. It is conducted clinical-and-laboratory and functional inspection 200 women with the underweight, from what 100 got the generally accepted diagnostic and treatmentand-prophylactic measures and 100 – an algorithm is improved by us. 30 expectant mothers madea control group. With the purpose of decline of frequency of unmaturing and other complications ofpregnancy it is necessary to use the followings moments: a hormonal and metabolic correction isindividually directed. Clinical, echographic, cariotocographic, doppler, biochemical, morphologicaland statistical.\u0000\u0000Results. The results of the conducted researches testify that in the structure of underweightfor women to pregnancy of decline of feed (IMT – 19,1±0,4) is 50%; oligotrophy I degree (IMT– 18,0±0,5) – 41% and oligotrophy of II-III of degree (IMT - 16,3±0,9) – 9% respectively. Totalfrequency of genital pathology to pregnancy for women with the underweight is 51,5%; violationsof menstrual function (16,5%) prevail among different nosology forms, in other cases of salpingooophoritis(9,5%); violation of genesial function (8,5%) and gynaecological operations are carried(9,5%). Set, that for pregnant with the underweight of growth of mass of body takes place, mainly(70–80%), due to thin mass. Fatty fabric makes small part (to 20%) of raise of weight, thatindemnification of underweight is not at pregnancy and the insufficient raise of weight takes placeat pregnancy for patients with low mass of body.\u0000\u0000Conclusion. The use of the improved algorithm of diagnostic and treatment-and-prophylacticmeasures allows to reduce frequency of threat of terminating pregnancy in І trimester (from 20% to10%; р<0,001), vomit of pregnant (from 14% to 6%; р<0,001), iron-deficiency anaemia in І trimester(from 36% to 16%; р<0,001), arterial hypertension (from 20% to 12%; р<0,001), bacterial vaginosis(from 10% to 4%; р<0,001). candidiasis (from 8% to 4%; р<0,001), threatened miscarriage in aІІ trimester (from 44% to 24%; р<0,05), iron-deficiency anaemia (from 74% to 50%; р<0,001),placenta disfunction (from 32% to 20%; р<0,05), intrauterine hypoxia (from 30% to 18%; р<0,001),delays of growth of fetus (from 12% to 6%; р<0,05), preeclampsia of middle and heavy degree (from22% to 6%; р<0,001). Frequency of urgent births is increased on 4%, and premature – goes downon 6% respectively.","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131598788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical and social features of matrimonial pair with infertility","authors":"O. Berestovoy","doi":"10.52705/2788-6190-2022-03-7","DOIUrl":"https://doi.org/10.52705/2788-6190-2022-03-7","url":null,"abstract":"The objective: is a study of modern medical and age-related aspects at infertility in a matrimonial pair.\u0000\u0000Materials and methods. A research object was become by sterile pair, by unit of supervisionis every sterile pair. By us was surveyed 100 matrimonial pair with infertility, a representativeselection was here formed in quality and to the amount with the use of method of systematicrandom sample.\u0000\u0000Results. Medical and social factors matter very much for the decision of question of realization ofgenesial function in matrimonial pair. A basic value is had the state of reproductive health of notonly woman but also man or partner, and also maintainances of stage of grant to the specializedmedicare, since womanish consultation concluding the specialized clinics of auxiliary genesialtechnologies.\u0000\u0000Conclusions. The got results must be taken into account at a grant to medicare to the matrimonialpair with violation of genesial function.","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"42 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121271609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pelvic pain and psycho­emotional status in women with ovarian endometrioma combined with pelvic inflammatory diseases: treatment options choice","authors":"R. Bihun, N. Henyk","doi":"10.52705/2788-6190-2022-01-3","DOIUrl":"https://doi.org/10.52705/2788-6190-2022-01-3","url":null,"abstract":"The connection between chronic pelvic pain and the presence in the body of a pathological source of structural and morphological changes in tissue, e.g. in connection with uterine fibroids, endometriosis, chronic inflammatory processes of the pelvic organs remains a traditional opinion. Endometriosis, which is characterized by a chronic pelvic pain, affects about 10% of women of\u0000reproductive age, and the problem of studying of endometrioid cysts demonstrates its relevance by dominating in the structure of genital endometriosis up to 59%. Chronic pelvic pain causes inappropriate courses of antibacterial therapy and, as a consequence,\u0000dysbiosis, the development of ovarian insufficiency syndrome, and the surgical approach does not always show the desired results, often worsening the clinical picture and psycho-emotional status of the patient.\u0000The objective: of this study was to assess the severity of the pain syndrome and psychological status in patients with pelvic pain associated with ovarian endometrioma and to seek effective therapeutic options.\u0000Materials and methods. The study included 40 patients with ovarian endometriosis combined with pelvic inflammatory disease (main group) and 40 patients with isolated endometrioma (comparison group). The control group consisted of 30 patients without manifestations of genital endometriosis. Analysis of somatic and gynecological anamnesis was used, as well as the objective and gynecological examination, data from adapted Beck’s Depression Inventory and State-Trait Anxiety Inventory, pain assessment according to the visual-analog scale (VAS), sonographic examination of the pelvic organs, evaluation of magnetic resonance imaging, endoscopic and histological methods of examination.\u0000Results. Dyspareunia was noted in one third of patients of the main group; dysuric manifestations, intestinal disorders in one in four women, a combination with manifestations of asthenic-neurotic syndrome in a third of women, the intensity of pain was presented in a third as severe and unbearable. It should be noted that the percentage of secondary infertility increased by 2.6 times,\u0000in two thirds of cases there were menstrual disorders, which were dominated by manifestations of algodysmenorrhea and abnormal uterine bleeding. The analysis of psychological questionnaires noted equal percentage of moderate and mild\u0000depressive symptoms in the main group, as well as, along with a decrease in psychological and emotional adaptation, high rates of situational and personal anxiety. Proposed therapeutic options included the use of dienogest primarily in women with mild to moderate pain syndrome, the possibility of long-term use at risk of recurrence and taking into account the smaller percentage\u0000of probable side effects.\u0000Conclusions. The analysis of the obtained data allowed to indicate to more intense pain syndrome, high frequency of menstrual disorders, secondary infertility and manifestations of nonspecific clinical symptoms in patients","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127844909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Features of pregnancy, childbirth and postpartum in women with uterine leiomyoma","authors":"","doi":"10.52705/2788-6190-2022-01-1","DOIUrl":"https://doi.org/10.52705/2788-6190-2022-01-1","url":null,"abstract":"The objective: to determine the effect of uterine fibroid on the features of pregnancy, childbirth and possible complications during pregnancy delivery and postpartum.\u0000Materials and methods. We analyzed 10684 histories of pregnancy and childbirth for 3 years (2019–2021). The main group of pregnant women included 363 cases with fibroid (3.39% of the total). The comparison group consisted of pregnant women without fibroid (10,321 births (96.61% of total)).\u0000Results. We found that the following factors as the age of the pregnant woman, high BMI, smoking and alcohol consumption were of significant risk (p<0.05) regarding the fibroid progression and its effect on the course of pregnancy, which affected the development of gestational diabetes and hypertensive disorders in pregnant women with fibroid. The rate of delivery by caesarean section in women with fibroid reached 59.0% compared with 23.4% in the group without fibroid (p<0.001). An association between fibroid and an increased risk of caesarean section was confirmed (OR 4.7; 95% CI: 3.8–5.8). The size of the fibroid node significantly increased the likelihood of placentation pathology as placenta previa in the subgroup with the size of the node >5 cm, the likelihood of preterm birth, as well as the volume of postpartum hemorrhage (p<0.05). The fibroid node type proved a statistically significant effect on the incidence of placental abruption, especially in the case of placental attachment close to the submucosal node compared with another type of nodes (intramural or subserous) – 6.9% vs. 0.8% respectively in the case of intramural fibroid and 0% for subserous fibroid p<0.01.\u0000Conclusions. According to the results of a retrospective study, we proved that pregnant women with uterine fibroid are at greater risk of complications of pregnancy, childbirth and the postpartum period. There is a direct relationship between pregnancy in the background of fibroid and the likelihood of placenta previa, increased frequency of caesarean section and the development of\u0000postpartum hemorrhage.The relationship between different characteristics of the uterine fibroid (its type, size, localization,\u0000number of nodes) and the likelihood of massive obstetric bleeding has been proven. We focus on the aspect of prognosis, determination by obstetrician-gynecologists of a high-risk group for developing postpartum hemorrhage in pregnant women with uterine leukemia for the purpose of timely prevention and treatment of massive obstetric hemorrhage and the development of\u0000coagulopathic disorders.","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"75 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131705205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modern aspects of patology in puberty period","authors":"Orysia Kovalyshin","doi":"10.52705/2788-6190-2022-01-4","DOIUrl":"https://doi.org/10.52705/2788-6190-2022-01-4","url":null,"abstract":"The woman’s health and its integral component – reproductive health – are largely determined by the conditions of her development in the womb, during the neonatal period, childhood, and adolescence.\u0000The article provides an analysis of modern research on the relationship of reproductive dysfunction since its inception, where there is a clear tendency to increase the number of patients with puberty pathology. The low level of somatic and reproductive health before pregnancy causes a high frequency of complicated births, leading to a deterioration in the development of subsequent\u0000generations.\u0000The woman’s reproductive system is the most dynamic biological object, which is extremely sensitive to adverse external and internal factors by the emergence of new adaptive reactions that acquire, under certain conditions, the properties of the pathological process. At the same time, many issues of the pathogenesis of fertility disorders have not been fully studied and remain\u0000controversial. Accordingly, not only the development of informative methods for assessing the state of the reproductive system, but also the problem of restoring reproductive health are becoming increasingly important. In such conditions, to improve the indicators of female reproductive health at all stages of its formation, it is necessary to improve and optimize the provision of gynecological and obstetric care.","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114737404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}