NAUKA MOLODYKH (Eruditio Juvenium)最新文献

{"title":"Right Hemicolectomy with Gastropancreatoduodenal Resection en bloc in 84-Year-Old Patient (Case Report)","authors":"M. Danilov, Olesya N. Solov’yeva, Anastasiya O. Nikolayeva, R. Alikhanov","doi":"10.23888/hmj2022102187-194","DOIUrl":"https://doi.org/10.23888/hmj2022102187-194","url":null,"abstract":"INTRODUCTION: Among the malignant neoplasms, colorectal cancer ranks third in the morbidity worldwide. Tumors of the right half of the colon are often symptomatic, which is an indication for extended and combined resections. Invasion into the neighboring tissues and organs indicates aggressiveness of the tumor biology, however, it is not always associated with the remote metastasizing process. Previously, invasion into the duodenum and/or pancreas was considered to be a non-resectable case, and as a rule, such patients underwent explorative laparotomy and were prescribed supporting medicinal therapy. However, recently some publications appeared on performing multivisceral resections in locally advanced cancer of the right half of the ascending colon with positive long-term results. In the given clinical case, a successful experience of radical surgical intervention in an elderly patient with locally advanced cancer with destruction and invasion into the duodenum is presented. CONCLUSION: Compliance with the oncological principles at each stage of the operation, precise preoperative diagnosis and preparation of the patient for surgical intervention can have a favorable outcome in the process of further treatment and survival of the patient.","PeriodicalId":417948,"journal":{"name":"NAUKA MOLODYKH (Eruditio Juvenium)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128994914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Difficulties in Diagnosing Aortic Dissection in Real Clinical Practice","authors":"Oleg M. Uryas’yev, L. A. Zhukova, S. Glotov, E. Alekseyeva, I. Ponomareva, M. S. Yakushina","doi":"10.23888/hmj202210163-74","DOIUrl":"https://doi.org/10.23888/hmj202210163-74","url":null,"abstract":"INTRODUCTION: The clinical presentation of aortic dissection (AD) is diverse. Along with the classic signs, there are many “masks” that create difficulties in differential diagnosis with diseases having similar symptoms. The difficulties in the diagnosis of AD include rare incidence of the pathology, atypism of the clinical symptoms which can be interpreted as ischemic heart disease, hypertensive crisis, pulmonary embolism, aortic heart disease, neurological pathology, acute surgical pathology, renal colic. In the reported cases, there were symptoms that should have put the doctor on the alert for AD. So, in the first case there were an acute onset with a sharp rise in blood pressure, unusual irradiation of anginal pain to the lumbar region, asymmetry of the pulse and blood pressure on the extremities, development of gangrene of the right leg. In the second case, the symptomatology of degenerative-dystrophic lesion of the spine prevailed, for which the appropriate treatment was given for ten days. Symptoms suggestive of AD: expansion of the abdominal aorta on magnetic resonance imaging of the spine that could suggest involvement of the thoracic aorta in the pathological process, the presence of anemia. The third case — symptomatically classic variant of AD: severe anginal status, pulse and blood pressure asymmetry. Such symptoms as nausea, vomiting, diarrhea, and most importantly, short duration of the observation, did not permit to make a correct diagnosis on admission. In all clinical observations, the analysis of complaints, history, physical and instrumental data ultimately permitted to diagnose AD. CONCLUSION: For the timely diagnosis of AD, it is important to use available methods of instrumental diagnostics, from routine to high-tech ones. Before routing a patient to the department of vascular surgery, it is necessary to provide medical care aimed at slowing down AD, stabilization of hemodynamics, and anesthesia.","PeriodicalId":417948,"journal":{"name":"NAUKA MOLODYKH (Eruditio Juvenium)","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116048692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trust–Based Relationship between Patient and Doctor as Guaranty of Successful Management of Dental Implantation Complications","authors":"Evgeniya A. Durnovo, Inga I. Chekareva, Aleksandr V. Grekhov, A. Kochubeynik, A. I. Korsakova","doi":"10.23888/hmj202210191-100","DOIUrl":"https://doi.org/10.23888/hmj202210191-100","url":null,"abstract":"INTRODUCTION: One of the topical problems of modern medicine is absence of the patients trust in the doctor, which affects the success of treatment of complications of dental implantation. The effectiveness of the practical activities of the doctor depends on how professionally he constructs the interaction with patients, their relatives and legal representatives, and, certainly, with colleagues. Surgical manipulations are often associated with negative emotions, distress, which can affect the result of a surgical intervention. The ability of the doctor to convince the patient, to form effective interaction and to set the patient up for successful recovery, using various psychological techniques, plays an important role in establishment of an emotional balance in all stages of treatment and after it. This is especially important on a visit to a dentist, since surgical interventions in the oral cavity are accompanied by pronounced reactions of an organism, such as swelling, hyperemia, hematomas, as well as functional disorders. Here, the fundamental point will be the patients trust in the doctor, who, in turn, must explain all the necessity and correctness of this treatment. Good medical care is inconceivable without the psychological support of patients preparing for or undergoing surgery. Partial and complete tooth loss due to various causes is one of the most common diseases of the oral cavity in the population. The most popular way to solve this problem is rehabilitation of patients with dental implantation. Like all surgical procedures, these manipulations are accompanied by strong emotional sufferings, anxiety, stress of the patient and not a simple postoperative period. CONCLUSION: That is why further search and development of new stress suppressing drugs and methods is an urgent problem and a promising trend in the rehabilitation of patients of a dental surgeon.","PeriodicalId":417948,"journal":{"name":"NAUKA MOLODYKH (Eruditio Juvenium)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127062517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Implementation of Information System in a Regional Hospital in the Framework of Introduction of a New Model of Provision of Primary Medical Care","authors":"A. A. Kurmangulov, Aleksey A. Kononykhin, N. S. Brynza","doi":"10.23888/hmj202210123-32","DOIUrl":"https://doi.org/10.23888/hmj202210123-32","url":null,"abstract":"BACKGROUND: In accordance with the draft order of Ministry of Health of Russian Federation, it is supposed to create three levels of compliance with the new model in which the criterion of the information system is obligatory for achievement of the first level. In this regard, of interest for health officials is theoretical and clinical validation of the methods of evaluation of the system of visualization in medical organizations in different territories, described in methodical recommendations of the Healthcare Ministry of RF. AIM: To study the features of visualization of a medical information system in a structural unit of a central regional hospital providing primary medical care. MATERIALS AND METHODS: The object of the study was the information system of an adult polyclinic of the central district hospital, where the information system was evaluated, with the subsequent filling out of a checklist of achievement of the target value of the criterion “Implementation of an information system in a medical organization”. The subject of the study was the basic characteristics of the information system: the amount, method of placement, reasonability, relevance and availability of individual elements. RESULTS: In accordance with the checklist for evaluating the information system in a medical organization, the percentage of the presence of information was 33%, which led to non-compliance with the criterion “Implementation of an information system in a medical organization”. In addition, during the audit, 17 elements of the information system were identified not related to any of 18 points of the analyzed criterion. These elements were combined in the block “Information aimed at ensuring a safe stay in a medical organization”, which is proposed to supplement the existing sections of the criterion “Implementation of an information system in a medical organization”. CONCLUSION: To achieve the first level of compliance with the new model of a medical organization providing primary health care, it is necessary to meet the requirements of the criterion “Implementation of an information system in a medical organization”. It is advisable to consider the possibility of including elements of an information system aimed at ensuring the safety of visitors and staff staying in a medical organization, in the criterion “Implementation of an information system in a medical organization”.","PeriodicalId":417948,"journal":{"name":"NAUKA MOLODYKH (Eruditio Juvenium)","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116007335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Function of the Apparatus of External Respiration in Lung Cancer Developed with the Underlying Chronic Obstructive Pulmonary Disease","authors":"Nadezhda E. Pukayeva, Diana S. Miller, Y. Porovskiy, S. Miller","doi":"10.23888/hmj202210115-22","DOIUrl":"https://doi.org/10.23888/hmj202210115-22","url":null,"abstract":"INTRODUCTION: Clinical observations ascertain a comorbid development of chronic obstructive pulmonary disease (COPD) and lung cancer (LC). Here, a more favorable prognosis for patients with LC depends on detection of the disease in early stages, when radical treatment is possible. This determines the importance of a detailed examination of the function of the external respiration using modern methods to identify predictors of lung cancer. AIM: To study the peculiarities of disorders in the apparatus of external respiration (AER) in patients with LC developed with the underlying COPD (LC + COPD). MATERIALS AND METHODS: A clinical and functional examination of 33 individuals was conducted — 10 healthy (control group), 12 patients with COPD and 11 patients with LC + COPD, using methods of spirography, pneumotachography and body plethysmography. RESULTS: In patients with COPD, as well as in those with LC + COPD, a statistically significant decrease in the median values of vital capacity of lungs (VCL), forced expiratory volume in 1 second (FEV1), flow-volume curve (PFER, MEF50, MEF75) and an increase in respiratory minute volume (RMV), residual lung volume (RLV), the ratio of residual lung volume to total lung capacity (RLV/TLC) and bronchial resistance (Raw) were revealed. It was found that in patients with LC + COPD, the median values of VСL, RLV/TLC, Raw did not differ, while the values of flow-volume curve were reduced as compared to patients with COPD. The observed decrease in the air flow rate parameters in the absence of differences in Raw indicates the extrapulmonary causes of these changes. CONCLUSION: In the course of the study, high reserve capacities of the apparatus of external respiration were found. The obtained parameters turned out to be of low informative value for diagnosis of development of LC with the underlying COPD. In patients with LC + COPD, the study of AER function, in addition to spirography and pneumotachography, should include body plethysmography, to avoid overdiagnosis of broncho-obstructive syndrome.","PeriodicalId":417948,"journal":{"name":"NAUKA MOLODYKH (Eruditio Juvenium)","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123655681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benign Hyperbilirubinemia of Gilbert Type","authors":"N. Asfandiyarova, A. G. Yakubovskaya","doi":"10.23888/hmj202210175-80","DOIUrl":"https://doi.org/10.23888/hmj202210175-80","url":null,"abstract":"INTRODUCTION: Benign hyperbilirubinemia of Gilbert type affects 10% of population, most commonly men of 20–30 years of age. In the article, description of a classic clinical case illustrating the course of Gilbert syndrome, is given. After an intercurrent infection, a 32-year old man presented with jaundice with elevation of the level of unconjugated bilirubin against the normal background level of enzymes. Bearing in mind a probability of being excluded from the flight crew, the patient agreed to the puncture biopsy of the liver, and the morphological examination of the hepatic tissue confirmed the diagnosis of benign hyperbilirubinemia of Gilbert type. A molecular genetic examination also showed the existence of tyrosine-arginine repeats in the promotor region of uridine diphosphate–glucuronosyltransferase gene. Adequately selected treatment with phenobarbital stimulating the activity of the enzyme, led to normalization of bilirubin level and to improvement of the patient’s well-being. CONCLUSION: Chronic familial non-hemolytic hyperbilirubinemias are often given insufficient attention not only due to the fact that their outcomes do not pose a serious threat to the patient’s health, and, according to the erroneous opinion, are rare, but to a larger extent due to the fact that the diagnosis presents certain difficulties for a therapist or a general practitioner.","PeriodicalId":417948,"journal":{"name":"NAUKA MOLODYKH (Eruditio Juvenium)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129514034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphofunctional Peculiarities of Mast Cells in Burn Wound with Application of Collagen Matrix","authors":"T. M. Cherdantseva, Ivan P. Chernov, T. M. Gromova, V. V. Shelomentsev","doi":"10.23888/hmj20221015-14","DOIUrl":"https://doi.org/10.23888/hmj20221015-14","url":null,"abstract":"INTRODUCTION: It is known from the literature data that mast cells (MC) promote suppression of active inflammation and the transition of the process to the stage of proliferation. However, there is still not enough data in the scientific literature on the morphofunctional peculiarities of mast cells in case of application of a collagen matrix onto the burn surface. AIM: To study the morphofunctional peculiarities of mast cells in wound burn regenerate in rats with application of a collagen matrix. MATERIALS AND METHODS: The study was carried out on 21 male Wistar rats, which were divided into 3 groups (control, experimental, intact). In rats of the control and experimental groups, a burn was modeled. In the control group, the burn was left untreated. In the experimental group, after modelling a burn wound, a collagen matrix was transplanted onto the burn surface. In the intact group, the rats were not subjected to any experimental influences. As a collagen matrix, COLLOST® collagen absorbable material was used. To assess the dynamics of burn wound healing, planimetric studies of the wound surface were performed. To analyze the morphofunctional peculiarities of mast cells, their number and shape were studied, the degranulation coefficient (DC) and the average area of one MC were calculated. RESULTS: A decrease in the number, average area and degranulation coefficient of MC, as well as a decrease in the severity of the inflammatory reaction and a lag in the formation of granulation tissue in the group with use of the collagen matrix, were found. CONCLUSIONS: With use of a collagen matrix, the functional activity of MC increased by the 7th day, which was confirmed by a number of parameters: a decrease in the area of the cell itself and an increase in the number of degranulated cells. The application of a collagen matrix reduced the response to inflammation manifested by decreased leukocyte infiltration and formation of a smaller area of granulation tissue.","PeriodicalId":417948,"journal":{"name":"NAUKA MOLODYKH (Eruditio Juvenium)","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123578765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors for Health in Students in terms of Reforming the System of Secondary Vocational Education","authors":"Anastasiya V. Sokolovskaya, O. V. Kazaeva, Anna O. Silkina","doi":"10.23888/hmj2022101113-122","DOIUrl":"https://doi.org/10.23888/hmj2022101113-122","url":null,"abstract":"INTRODUCTION: The modern system of secondary vocational education is quite popular among applicants, and working professions become a conscious choice of the younger generation and a kind of guarantee of a successful career start. This became possible due to the perspective approach of the Ministry of Education of Russia to salvation of this problem. Among the effective solutions of the program-targeted approach are a demonstration exam as an independent assessment of the practical skills of students and graduates of vocational schools, career guidance projects for schoolchildren, open online classes, international, national championships and competitions in professional skills. In recent years, significant changes have also touched upon the infrastructure of educational institutions. Modern colleges and technical schools should become the advanced platforms reflecting the challenges of the time. In this regard, the Ministry of Education of Russia has elaborated promising directions for the development of the secondary vocational education system: - constant updating of the content and technologies of vocational education and training in accordance with current and prospective requirements to the qualifications of employees, the development of technologies; - formation of a new landscape of the network of secondary vocational education, providing a flexible response to socio-economic changes, harmonization of education and training results with the requirements in the field of labor; - increase in the financial stability and targeted support for organizations engaged in educational activities for the training of workers (employees) and mid-level specialists; - bringing the qualifications of the management and teaching staff of colleges in line with the modern requirements to personnel; - development of professional competitiveness in the system of secondary vocational education to improve the effectiveness of educational and project activities. The implementation of these directions will require special attention to the health of adolescents, since vocational education is a key element in the transition from childhood to independent active life, and is characterized by significant peculiarities of the activity that play a positive role in the development of a person, and at same time have some negative influences associated with the complexity of adaptation of yesterdays schoolchildren to the factors of the industrial environment and the new realities of independent life. CONCLUSION: Thus, it can be concluded that adolescents studying in the system of secondary vocational education, represent a special social group of the population united by certain age boundaries, physiological and hygienic peculiarities, intensive mental work in the process of vocational education, mastering of industrial process, lifestyle. Therefore, in planning and conduction of research work, special attention should be given to the issue of formation of not only professio","PeriodicalId":417948,"journal":{"name":"NAUKA MOLODYKH (Eruditio Juvenium)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122837982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Observation of Children of the Newborn Period in Childrens Polyclinic","authors":"E. I. Akhmedova","doi":"10.23888/hmj202210181-90","DOIUrl":"https://doi.org/10.23888/hmj202210181-90","url":null,"abstract":"INTRODUCTION: Primary health care is a fundamental element in protecting the health of the children’s population. This article presents a literature review on the problems of providing medical care to children of the first month of life. One of the main stages in an integrated approach to observation of children is the antenatal protection of the fetus, which is provided primarily by childrens clinics through prenatal patronage. To date, at this stage, there is still lack of coordination in the work of womens clinics and childrens clinics. After the discharge of newborns, prenatal care is replaced by home care for newborns, which is realized by both a doctor and a district nurse and represents a complete system with an integrated approach to appropriate examinations. Observance of the frequency of both prenatal and primary patronages, which is regulated by the federal normative acts, is ensured by the professional level of district pediatricians and district nurses, as well as by the appropriate provision of the primary link with personnel. Lack of specialists in medical organizations providing primary health care to children is reflected in the increased burden on the medical and nursing staff. According to the research conducted in different regions of the Russian Federation, the number of population attached to a health locality, often significantly exceeds the recommended standard of 800 people per one locality. All this leads to non-standardized loads on the staff, and has a significant impact on the quality of medical care provided. This, in turn, leads to dissatisfaction of the patients legal representatives with the availability, quality and completeness of the medical care provided. CONCLUSION: The presented information, based on the data of the literature review devoted to the quality of medical care for children of the first month of life in childrens polyclinics, is aimed at optimizing the conditions for improving affordable and high-quality medical care, improving the health of the child population, reducing infant mortality.","PeriodicalId":417948,"journal":{"name":"NAUKA MOLODYKH (Eruditio Juvenium)","volume":"214 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134229132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adherence to Therapy in Polymorbid Patients with Chronic Heart Failure","authors":"Yuliya V. Omarova, E. Tarlovskaya, Aleksandr A. Mordvinov","doi":"10.23888/hmj202210145-52","DOIUrl":"https://doi.org/10.23888/hmj202210145-52","url":null,"abstract":"INTRODUCTION: Low adherence to doctors prescriptions turns into an increased risk of complications and high mortality for patients, and economic losses and deepening of negative demographic trends for the society. AIM: To study adherence to therapy in polymorbid patients with chronic heart failure (CHF). MATERIALS AND METHODS: The study included 313 patients hospitalized in the city center for treatment of chronic heart failure (CHF) in the period from February 1, 2019 to October 1, 2020 at the age of 75 ± 8.22 years. 66.77% Of patients were diagnosed with CHF with preserved left ventricular ejection fraction (EF), 19.81% — with intermediate, 13.42% — with low ejection fraction. Adherence to treatment was assessed by Morisky–Green questionnaire: 4 points — compliant patients, 2 and less points — non-compliant, 3 points — insufficiently compliant. RESULTS: In the groups, the majority of patients had arterial hypertension (AH) and coronary heart disease (CHD), 99.04% and 67.09%, respectively; 65.49% of patients had rhythm disorders in the form of atrial fibrillation or flutter (AFb/AFl); 20.45% of patients had chronic lung diseases, chronic obstructive pulmonary disease (COPD), 21.72% — malignant diseases, a third of patients (38.98%) — diabetes mellitus (DM), 14.69% — various joint diseases. Almost all patients (99.04%) with CHF were diagnosed with chronic kidney disease (CKD), 45.05% had anemia of different severity. The incidence of acute kidney injury (AKI) was higher in the group of compliant patients (30.59%, 35% and 44.72%; pmg = 0.046), mainly due to AKI diagnosed by the initial creatinine (pmg=0.038), predominantly of I stage (12.94%, 15% and 17.07%; pmg = 0.805). The groups were comparable in the frequency of AKI diagnosed in the hospital by the dynamics of creatinine (4.11%, 5% and 5.69%; pmg = 0.823). Patients did not differ in frequency until dialysis stages of chronic kidney disease (pmg = 0.763). CONCLUSION: Every third patient at the outpatient stage did not take drug therapy. Among non-compliant patients, there was a lower incidence of stable angina and joint diseases, a smaller number of patients with more than 5 diseases, they were more rarely hospitalized and more often had bad habits. On the contrary, in the group of compliant patients, there were more polymorbid patients with pain syndrome of different location, they were more often re-hospitalized.","PeriodicalId":417948,"journal":{"name":"NAUKA MOLODYKH (Eruditio Juvenium)","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125733010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}