Journal of the ASEAN Federation of Endocrine Societies最新文献

{"title":"A Rare Case of Catecholamine-Secreting Adrenal Myelolipoma.","authors":"Veenu Jain, Anshita Aggarwal, Bindu Kulshreshtha, Preeti Singh, Hemant Goel","doi":"10.15605/jafes.040.01.15","DOIUrl":"10.15605/jafes.040.01.15","url":null,"abstract":"<p><p>Adrenal myelolipoma (AML) is a rare, benign, asymptomatic, nonfunctioning tumor of the adrenal cortex detected incidentally. AML can be accompanied by several other endocrine disorders simultaneously. Here, we report a case of a 36-year-old female with primary hypothyroidism and metabolic syndrome accompanied by severe hypertension and pheochromocytoma. However, the histopathological examination of the excised adrenal gland confirmed myelolipoma. Following surgery, her plasma nor-metanephrine levels decreased to normal values and the patient became normotensive, which suggested that the mass was functioning.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"104-107"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Nutritional Status using the Short Nutritional Assessment Questionnaire (SNAQ) and Malnutrition Risk using the Malnutrition Screening Tool (MST) with In-Hospital Mortality and Intensive Care Unit Admission Among Non-Critically-Ill Patients: A Single Center, Prospective Cohort Study.","authors":"Karl Homer Nievera, Mark Henry Joven","doi":"10.15605/jafes.040.01.20","DOIUrl":"10.15605/jafes.040.01.20","url":null,"abstract":"<p><strong>Background and objective: </strong>Although nutritional assessment tools have been available internationally, local data for their use in foreseeing adverse outcomes among admitted patients are currently unavailable. The primary objective of this study was to determine the association of nutritional status using Short Nutritional Assessment Questionnaire (SNAQ) and malnutrition risk using the Malnutrition Screening Tool (MST) with intensive care unit (ICU) admission and in-hospital mortality.</p><p><strong>Methodology: </strong>This was a prospective-cohort study which included 122 purposively-selected adult participants who were non-intubated, admitted for medical and surgical management, stayed for at least 24 hours, had no COVID-19 infection, and were not admitted in any critical care unit. The SNAQ and MST questionnaires, which are validated tools and consists of two to three easy-to-answer questions, were used among the participants and their scores were tallied in order to get their nutritional status and malnutrition risk. Primary endpoints measured were the length of hospital stay, incidence of mortality, and ICU admission rate. Comorbidities were taken into account using the Charlson Comorbidity Index.</p><p><strong>Results: </strong>Categorizing the SNAQ scores showed 33.61% were severely malnourished, which was similar when using the MST classification, wherein 34.43% were at risk of malnutrition. None of the participants were admitted to the ICU. Malnutrition risk and nutritional status was not significantly associated with 30-day in-hospital mortality (p >0.05). On the other hand, results of the Cox proportional hazards showed that SNAQ and MST significantly predicted the hazard of 30-day in-hospital mortality, increasing the hazard of mortality by 2.58 times and 3.67 times, respectively, for every 1-unit increase in SNAQ and MST scores. Similarly, nutritional status using the SNAQ classification indicated the severely malnourished category significantly predicted the hazard of mortality, increasing it by 9.22 times for those who are severely malnourished. Also, malnutrition risk using the MST classification indicated that those who were at risk of malnutrition were 9.80 times greater hazard of mortality than those who were not at risk of malnutrition.</p><p><strong>Conclusion: </strong>The MST and SNAQ classification are screening tools for nutritional status (SNAQ) and malnutrition risk (MST) that can be administered at the onset of the patient's hospital course and have been demonstrated in this study to predict 30-day in-hospital mortality. It is important to note that none of the patients included in this study required intensive care unit admission.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"80-88"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Tumultuous Journey of Metastatic Pancreatic Neuroendocrine Tumor with Carcinoid Syndrome.","authors":"Somdatta Giri, Sadishkumar Kamalanathan, Kalayarasan Raja, Nandini Pandit, Dukhabandhu Naik, Jayaprakash Sahoo","doi":"10.15605/jafes.040.01.04","DOIUrl":"10.15605/jafes.040.01.04","url":null,"abstract":"<p><p>A 25-year-old woman presented with metastatic pancreatic neuroendocrine tumor with carcinoid syndrome. She was refractory to octreotide and did not respond well to chemotherapy. Although surgical debulking remains the primary approach for managing these tumours, it entails inherent risks, including potentially exacerbating carcinoid syndrome. We strategically delivered the one Peptide Receptor Radionuclide Therapy cycle before tumor debulking, a decision that yielded a remarkable response, stabilizing her condition.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"112-116"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102652/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aplasia Cutis Congenita on the Scalp.","authors":"Supasuta Wongdama, Chutintorn Sriphrapradang","doi":"10.15605/jafes.040.01.11","DOIUrl":"10.15605/jafes.040.01.11","url":null,"abstract":"","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"136-137"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sociodemographic and Lifestyle Factors Associated with Undiagnosed Diabetes in Indonesia: Findings from the Basic Health Research Work of Riskesdas 2018.","authors":"Ayunina Rizky Ferdina, Juhairiyah, Windy Tri Yuana, Budi Setyawati, Dhita Elsha Pangestika","doi":"10.15605/jafes.040.01.21","DOIUrl":"10.15605/jafes.040.01.21","url":null,"abstract":"<p><strong>Background: </strong>As a developing nation, there has been an increasing trend in non-communicable diseases, including diabetes mellitus (DM) in Indonesia. However, a remarkable proportion of DM cases in this archipelagic country is likely undiagnosed.</p><p><strong>Objective: </strong>This study assessed the sociodemographic and lifestyle factors related to undiagnosed DM in Indonesians.</p><p><strong>Methodology: </strong>This cross-sectional study analyzed secondary data from the 2018 Indonesian Basic Health Research (Riskesdas). It involved 3,755 study subjects, 3,619 individuals with high blood glucose levels meeting the DM criteria and 136 individuals with controlled DM. Multivariable regression analysis examined the associations between sociodemographic and lifestyle factors and undiagnosed diabetes.</p><p><strong>Results: </strong>The study revealed that 80% of the DM cases among the subjects were undiagnosed. Multivariable analysis confirmed that age group, area of residence, employment, wealth quintiles and physical activity were significantly associated with higher odds of undiagnosed diabetes. Notably, sex, smoking status and vegetable consumption did not show any association with the diagnosis status of diabetes.</p><p><strong>Conclusion: </strong>A significant portion of DM cases in Indonesia remain undiagnosed, especially among young adults, rural residents, agricultural workers and lower socioeconomic groups. Improved healthcare access, targeted screening and enhanced health education are essential to ensure early diagnosis and effective management of diabetes.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"53-60"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Editor-in-Chief's Reflections on a 15-Year Journey.","authors":"Elizabeth Paz-Pacheco","doi":"10.15605/jafes.040.01.01","DOIUrl":"https://doi.org/10.15605/jafes.040.01.01","url":null,"abstract":"","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"4-5"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Raised Bisphenol A has a Significant Association with Adverse Reproductive Manifestations Rather than Biochemical or Hormonal Aberrations in Women with Polycystic Ovary Syndrome.","authors":"Emran-Ur-Rashid Chowdhury, Hurjahan Banu, Md Shahed Morshed, Iffat Ara Jahan, Subi Kharel, Muhammad Abdul Hasanat","doi":"10.15605/jafes.040.01.14","DOIUrl":"10.15605/jafes.040.01.14","url":null,"abstract":"<p><strong>Background: </strong>Bisphenol A (BPA) is a widely used industrial element. Recently it is suspected that BPA may disrupt the endocrine system to influence the manifestations of polycystic ovary syndrome (PCOS).</p><p><strong>Objective: </strong>This study aimed to assess serum BPA level and its association with manifestations of PCOS in women.</p><p><strong>Methodology: </strong>This cross-sectional study included 40 young adults with PCOS and 38 age-matched control women [23.0 (20.0, 29.0) vs. 25.0 (21.0, 29.0), years, median (IQR), <i>p</i> = 0.406]. After a thorough clinical examination, fasting blood was collected in the follicular phase of the menstrual cycle to measure glucose, lipids, insulin, luteinizing hormone, folliclestimulating hormone, total testosterone, sex hormone binding globulin, dehydroepiandrosterone sulfate, and BPA. Glucose was measured by glucose oxidase, lipids by glycerol phosphate dehydrogenase-peroxidase, all hormones including SHBG by chemiluminescent immunoassay and BPA by sandwiched enzyme-linked immunosorbent assay. Insulin resistance was measured using homeostasis model assessment of insulin resistance.</p><p><strong>Result: </strong>Women with PCOS had significantly higher BPA levels (ng/mL) than the control group [27.30 (25.60, 33.40) vs. 24.0 (15.58, 28.70), median (IQR), <i>p</i> = 0.001]. Using the 75^th percentile value of the control group, 15 (37.5%) women with PCOS had high BPA levels. Those with high BPA levels had a significantly higher frequency of menstrual regulation / abortion among women with PCOS [53.8% vs. 0%, <i>p</i>= 0.005]. Women with PCOS with a history of menstrual regulation / abortion [36.7 ± 4.9 vs. 28.5 ± 6.4, mean ± SD, <i>p</i> = 0.004] and subfertility [34.3 ± 6.8 vs. 28.5 ± 6.4, mean ± SD, <i>p</i> = 0.031] had higher levels of BPA than those without the histories. Serum BPA had no significant association or correlation with any androgenic and metabolic manifestations.</p><p><strong>Conclusion: </strong>Raised BPA level may be associated with adverse reproductive features in PCOS.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"26-31"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the Filipino Version of the Diabetes Distress Scale for Adult Patients with Diabetes seen at the Outpatient Department of a Tertiary Government Hospital in Quezon City, Philippines.","authors":"Margarette Rose Pajanel, Irish Judy Gonzales","doi":"10.15605/jafes.040.01.05","DOIUrl":"10.15605/jafes.040.01.05","url":null,"abstract":"<p><strong>Introduction: </strong>Caring for persons with diabetes involves a holistic approach. Addressing diabetes distress is crucial to achieve optimal health outcomes for persons with diabetes. This study aims to validate a Filipino version of the diabetes distress scale (DDS).</p><p><strong>Methodology: </strong>We conducted forward and backward translations to construct a Filipino version from the validated English questionnaire. We performed statistical analysis to check internal consistency and validation and to correlate diabetes distress with glycemic control based on the subjects' HbA1c levels.</p><p><strong>Results: </strong>We included one hundred and seventy patients (170) seen at the Outpatient Diabetes Clinic in the analysis. Of the participants, 13 (7.6%) have Type 1 Diabetes Mellitus (T1DM), while the rest have Type 2 (T2DM). We found physician distress (PD) to be significantly associated with having T1DM. All domains in the Filipino DDS showed good internal consistency, ranging from 0.81 to 0.85. We used factor analysis to extract four factors similar to the original diabetes distress scale. We did not find any significant correlation between diabetes distress and HbA1c level.</p><p><strong>Conclusion: </strong>The Filipino DDS showed good internal reliability and had consistent results similar to the original diabetes distress scale. However, we did not find a significant correlation between diabetes-related distress and the HbA1c level.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"61-71"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Consensus for Pituitary Adenoma Diagnosis in Indonesia.","authors":"Dicky Levenus Tahapary, Selfy Oswari, Maya Kusumawati, Dian Anindita Lubis, Tania Tedjo Minuljo, Reyhan Eddy Yunus, Henry Kodrat, Affan Priyambodo Permana, Martha Rosana, Johanes Purwoto, Leny Puspitasari, Hermina Novida, Himawan Sanusi, Syntia Nusanti, Tri Juli Edi Tarigan, Pradana Soewondo, Ketut Suastika","doi":"10.15605/jafes.040.01.03","DOIUrl":"10.15605/jafes.040.01.03","url":null,"abstract":"<p><p>Pituitary adenomas account for 10 to 15% of all intracranial masses and are the most common type of pituitary disorder. Their clinical manifestations can vary based on the tumor size and whether they secrete excess hormones. Occasionally, they are incidentally diagnosed following an imaging procedure for other indications (pituitary incidentaloma). The Pituitary Working Group of the Indonesian Society of Endocrinology has identified pituitary adenoma as a priority and has called for the development of updated evidence-based practice guidelines. These guidelines aim to provide evidence-based, comprehensive and multidisciplinary recommendations for diagnosing pituitary adenomas in Indonesia and to navigate the limitations of diagnosing pituitary adenomas in Indonesia.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"8-13"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative Complications Associated with Routine Preoperative Glucocorticoid Use Among Patients Undergoing Pituitary Surgery with Normal Preoperative HPA Axis: A Retrospective Cohort Study.","authors":"Franz Michael Magnaye, Elizabeth Paz-Pacheco","doi":"10.15605/jafes.040.01.06","DOIUrl":"10.15605/jafes.040.01.06","url":null,"abstract":"<p><strong>Objective: </strong>This study determined the incidence of perioperative complications associated with routine preoperative glucocorticoid use in patients undergoing pituitary surgery with normal preoperative hypothalamo-pituitary-adrenal axis (HPA axis).</p><p><strong>Methodology: </strong>From 2011-2021 retrospective chart review, 243 patients undergoing pituitary surgery with normal preoperative HPA axis were analyzed into 2 groups: 1) with preoperative steroids; and 2) without preoperative steroids. Development of postoperative complications was subsequently evaluated.</p><p><strong>Results: </strong>Incidence of primary composite postoperative complications of in-hospital mortality, postoperative infection and postoperative diabetes insipidus (DI) was significantly increased among those who had preoperative steroids compared to those without (58.33% versus 33.33%, <i>p</i>-value 0.004) with an adjusted odds ratio of 2.90 (CI 1.29 to 6.53, <i>p</i>-value 0.010). Among the components of the composite outcome, post-operative DI was statistically higher among those who were given preoperative steroids (52.45% versus 28.21%, <i>p</i>-value 0.006) with an adjusted OR of 3.31 (CI 1.43 to 7.67, <i>p</i>-value 0.005). The incidence of postoperative adrenal insufficiency was similar between the 2 groups (20.15% with steroids versus 8.70% without steroids, <i>p</i>-value 0.258).</p><p><strong>Conclusion: </strong>Among patients undergoing pituitary surgery with normal preoperative HPA axis, routine preoperative steroids use was associated with an increased risk of composite postoperative complications.</p>","PeriodicalId":41792,"journal":{"name":"Journal of the ASEAN Federation of Endocrine Societies","volume":"40 1","pages":"89-96"},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097979/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}