Samuel Legeay (Maître de conférences des universités), Sébastien Faure (Professeur des universités)
{"title":"Association spiramycine-métronidazole et escitalopram","authors":"Samuel Legeay (Maître de conférences des universités), Sébastien Faure (Professeur des universités)","doi":"10.1016/j.actpha.2025.02.004","DOIUrl":"10.1016/j.actpha.2025.02.004","url":null,"abstract":"<div><div>La coadministration de plusieurs médicaments allongeant de façon importante l’intervalle QT, comme l’escitalopram, la spiramycine et le métronidazole, expose à un risque de torsades de pointes susceptibles de provoquer une fibrillation ventriculaire qui engage le pronostic vital. Le pharmacien d’officine joue un rôle de première ligne dans l’identification de ces interactions et peut proposer une alternative thérapeutique. D’autres situations potentialisent également l’allongement de l’intervalle QT induit par certains médicaments.</div></div><div><div>The coadministration of several drugs that significantly prolong the QT interval, such as escitalopram, spiramycin and metronidazole, exposes patients to the risk of torsades de pointes, which can degenerate into life-threatening ventricular fibrillation. The dispensing pharmacist plays a front-line role in identifying these interactions, and can suggest a therapeutic alternative. Other situations also potentiate QT interval prolongation induced by certain drugs.</div></div>","PeriodicalId":41434,"journal":{"name":"Actualites Pharmaceutiques","volume":"64 645","pages":"Pages 13-15"},"PeriodicalIF":0.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143716230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jean-Michel Mrozovski (pour la valorisation de l’acte officinal (CVAO))
{"title":"Accompagner une patiente atteinte d’endométriose à l’officine","authors":"Jean-Michel Mrozovski (pour la valorisation de l’acte officinal (CVAO))","doi":"10.1016/j.actpha.2025.02.012","DOIUrl":"10.1016/j.actpha.2025.02.012","url":null,"abstract":"<div><div>L’endométriose est une pathologie à prendre en compte, synonyme de douleurs, voire d’infertilité. À l’officine, il convient d’être à même d’en discuter avec la patiente concernée, sans dramatiser son tableau clinique et ses conséquences, tout en lui proposant un accompagnement utile et efficace.</div></div><div><div>Endometriosis is a pathology to be taken into account, synonymous with pain and even infertility. At the pharmacy, you need to be able to discuss the condition with the patient concerned, without dramatizing the clinical picture and its consequences, while offering useful and effective support.</div></div>","PeriodicalId":41434,"journal":{"name":"Actualites Pharmaceutiques","volume":"64 645","pages":"Pages 45-48"},"PeriodicalIF":0.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143716117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Évaluez-vous !","authors":"Élisa Derrien (Rédactrice en chef)","doi":"10.1016/j.actpha.2025.02.016","DOIUrl":"10.1016/j.actpha.2025.02.016","url":null,"abstract":"<div><div>Ce QCM vous permet de vérifier les connaissances acquises à la lecture du numéro d’<em>Actualités pharmaceutiques</em>.</div></div>","PeriodicalId":41434,"journal":{"name":"Actualites Pharmaceutiques","volume":"64 645","pages":"Pages 62-64"},"PeriodicalIF":0.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143716121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PharmD, PhD student Laura Obry, PhD PharmD, Professor of University Guylène Page
{"title":"Les psychobiotiques, une révolution thérapeutique en devenir","authors":"PharmD, PhD student Laura Obry, PhD PharmD, Professor of University Guylène Page","doi":"10.1016/j.actpha.2025.02.005","DOIUrl":"10.1016/j.actpha.2025.02.005","url":null,"abstract":"<div><div>Le microbiote intestinal joue un rôle clé dans le maintien de la santé. Ses impacts sur le cerveau <em>via</em> l’axe microbiote-intestin-cerveau ouvrent aujourd’hui de nouvelles perspectives thérapeutiques pour les maladies neurodégénératives et psychiatriques. Les psychobiotiques, nouvelle classe thérapeutique, semblent prometteurs dans la modulation de ce lien bidirectionnel, notamment dans le cadre du trouble du spectre de l’autisme et de la maladie d’Alzheimer. Cette revue de littérature explore les mécanismes d’action et les applications potentielles des psychobiotiques dans les stratégies thérapeutiques modernes.</div></div><div><div>The intestinal microbiota plays a key role in maintaining health. Its impact on the brain via the microbiota-gut-brain axis is opening up new therapeutic prospects for neurodegenerative and psychiatric diseases. Psychobiotics, a new therapeutic class, show promise in modulating this bidirectional link, particularly in autism spectrum disorder and Alzheimer’s disease. This literature review explores the mechanisms of action and potential applications of psychobiotics in modern therapeutic strategies.</div></div>","PeriodicalId":41434,"journal":{"name":"Actualites Pharmaceutiques","volume":"64 645","pages":"Pages 16-20"},"PeriodicalIF":0.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143716231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mikaël Daouphars (Docteur en pharmacie, professeur associé de pharmacie clinique, pharmacien praticien)
{"title":"L’expérimentation Onco’Link, vers un parcours intégré du patient atteint de cancer","authors":"Mikaël Daouphars (Docteur en pharmacie, professeur associé de pharmacie clinique, pharmacien praticien)","doi":"10.1016/j.actpha.2025.02.009","DOIUrl":"10.1016/j.actpha.2025.02.009","url":null,"abstract":"<div><div>Dispositif organisationnel innovant, l’expérimentation nationale Onco’Link a permis la mise en place d’un accompagnement coordonné entre la ville et l’hôpital à destination des patients atteints de cancer et pris en charge par thérapie anticancéreuse orale. En ville, le pharmacien d’officine joue un rôle central grâce à la mise en œuvre d’entretiens pharmaceutiques et dans les échanges avec le centre de référence. Les résultats intermédiaires soulignent l’intérêt de cette expérimentation pour les patients et les professionnels de ville, et l’efficience induite pour le système de santé.</div></div><div><div>The innovative Onco’Link national experiment has set up a coordinated system of support for cancer patients receiving oral anti-cancer therapy. In the city, the dispensing pharmacist plays a central role through the implementation of pharmaceutical interviews and exchanges with the reference center. Interim results underline the value of this experiment for patients and healthcare professionals, and the resulting efficiency for the healthcare system.</div></div>","PeriodicalId":41434,"journal":{"name":"Actualites Pharmaceutiques","volume":"64 645","pages":"Pages 31-35"},"PeriodicalIF":0.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143716114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pour une meilleure prise en charge du patient cancéreux","authors":"Jérôme Sicard (Docteur en pharmacie)","doi":"10.1016/j.actpha.2025.02.011","DOIUrl":"10.1016/j.actpha.2025.02.011","url":null,"abstract":"<div><div>L’équipe officinale joue un rôle primordial dans le conseil et l’accompagnement des patients, en particulier au travers de la promotion de l’activité physique et de l’adhésion au traitement oncologique. Les travaux sur le microbiome permettent d’envisager de nouvelles perspectives dans la prise en soins des patients.</div></div><div><div>The pharmacy team plays a vital role in advising and supporting patients, in particular by promoting physical activity and adherence to oncology treatment. Work on the microbiome is also opening up new perspectives in patient care.</div></div>","PeriodicalId":41434,"journal":{"name":"Actualites Pharmaceutiques","volume":"64 645","pages":"Pages 41-44"},"PeriodicalIF":0.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143716116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arthur Piraux (Docteur en pharmacie, maître de conférences en pratiques officinales) , Cécile GuÉrard-Detuncq (Conseillère ordinale, professeure associée)
{"title":"Des expérimentations contribuant à la transformation du système de santé","authors":"Arthur Piraux (Docteur en pharmacie, maître de conférences en pratiques officinales) , Cécile GuÉrard-Detuncq (Conseillère ordinale, professeure associée)","doi":"10.1016/j.actpha.2025.02.006","DOIUrl":"10.1016/j.actpha.2025.02.006","url":null,"abstract":"","PeriodicalId":41434,"journal":{"name":"Actualites Pharmaceutiques","volume":"64 645","pages":"Page 21"},"PeriodicalIF":0.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143716122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Les hémorroïdes, maux fréquents de la grossesse","authors":"Aurore Blin (Docteure en pharmacie)","doi":"10.1016/j.actpha.2025.01.016","DOIUrl":"10.1016/j.actpha.2025.01.016","url":null,"abstract":"<div><div>Les hémorroïdes font partie des maux fréquents de la grossesse. Elles touchent 85 % des femmes enceintes au cours du deuxième et du troisième trimestre de grossesse. Les causes sont multiples et la gêne notable.</div></div>","PeriodicalId":41434,"journal":{"name":"Actualites Pharmaceutiques","volume":"64 644","pages":"Pages 59-60"},"PeriodicalIF":0.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143549043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vaccinations et vaccins, une riche actualité","authors":"Jacques Buxeraud (Professeur des universités)","doi":"10.1016/j.actpha.2025.01.002","DOIUrl":"10.1016/j.actpha.2025.01.002","url":null,"abstract":"","PeriodicalId":41434,"journal":{"name":"Actualites Pharmaceutiques","volume":"64 644","pages":"Page 1"},"PeriodicalIF":0.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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