Parasitologists United Journal最新文献

{"title":"Echinococcus granulosus protoscolex antigen used in serodiagnosis of hydatidosis by nano-gold dot-ELISA","authors":"Rashed Sm, M. Nasr, I. Shalash, Nagwa S. M. Ali, S. Kishik, A. El-Ghanam","doi":"10.21608/puj.2019.11387.1039","DOIUrl":"https://doi.org/10.21608/puj.2019.11387.1039","url":null,"abstract":"Background: Echinococcus granulosus protoscolex antigen (PSAg) is a protein with significant immunological properties having higher sensitivity and specificity in ELISA. It lowers cross-reaction with antibodies of other parasites and thus its application is recommended in serological diagnosis. Labelling of ELISA with nano-gold particles improved the diagnostic abilities of the laboratory technique in hydatidosis detection. \u0000Objective: To evaluate the use of nano-gold dot-ELISA for isolation of E. granulosus PSAg and its application in serodiagnosis of hydatidosis in humans and animals in comparison with dot-ELISA. \u0000Material and Methods: Hydatid cyst PSAg was isolated and used for immunization of rabbits to raise IgG polyclonal antibodies (pAb) in antisera. These sera were labeled with horseradish peroxidase (HRP) and used for detection of circulating PSAg in sera of human cases and camels and sheep by dot-ELISA and nano-gold dot-ELISA. \u0000Results: Conjugation of the anti-protoscolex pAb with gold nano-particles increased the sensitivity of antigen detection by nano-gold dot-ELISA to 94.4% and specificity to 90%, with positive and negative predictive values of 94.4% and 90%, and an accuracy of detection of 92.9% in both human and animal sera. \u0000Conclusion: Nano-gold dot-ELISA technique is more sensitive than dot-ELISA for detection of hydatidosis antigen both in human and animal samples","PeriodicalId":41408,"journal":{"name":"Parasitologists United Journal","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41601820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights into the interplay of latent toxoplasmosis, testosterone, cortisol and oxidative stress in screened schizophrenic patients in Egypt","authors":"N. El-Gebaly, M. Abdeltawab, Alshaimaa Hamed, Noha A. Mahfouz, S. Adel, A. Mahfoz, M. Rehan, E. Elsebaei","doi":"10.21608/puj.2019.11819.1040","DOIUrl":"https://doi.org/10.21608/puj.2019.11819.1040","url":null,"abstract":"Background: Toxoplasma gondii is a wide-spread infection. Most cases are asymptomatic latent toxoplasmosis and its link with schizophrenia is of wide interest. Toxoplasmosis induces immunopathological and neuroendocrine alterations that induce activation of hypothalamic pituitary-adrenal axis resulting in higher glucocorticoid and testosterone levels. Oxidative stress also has a role since antioxidants as glutathione (GSH) were found to be reduced. \u0000Objective: To assess seroprevalence/serointensity of toxoplasmosis in schizophrenic patients in relation to the levels of testosterone, cortisol and GSH activity in order to evaluate these factors in the etiopathogenesis of schizophrenic patients harboring latent toxoplasmosis. \u0000Subjects and Methods: In this cross sectional case control study, 120 schizophrenic inpatients were compared with 120 individuals attending the outpatients’ clinics in the same age range, and after exclusion of schizophrenia. Schizophrenia was confirmed or excluded using positive and negative syndrome scale (PANSS). Levels of Toxoplasma IgG, free testosterone, cortisol and GSH were determined in both groups. \u0000Results: Statistical analysis revealed no differences between cases and controls as regard age, gender, contact with pets, and Toxoplasma IgG seroprevalence. Toxoplasma IgG seroprevalence was higher in males compared to females and in rural areas than in urban areas. In Toxoplasma-positive patients, testosterone was higher in both genders and glutathione was lower, while no significant difference was documented in relation to PANSS, treatment with electroconvulsive-therapy (ECT) or cortisol level. Schizophrenic patients showed higher Toxoplasma antibody titer, cortisol, free testosterone levels in both genders and lower GSH than control. Male schizophrenic patients particularly showed lower GSH level and higher Toxoplasma antibody titer. Free testosterone level was significantly higher in male patients who had received ECT. \u0000Conclusion: Latent toxoplasmosis may be involved in the etiology of schizophrenia. Screening and treatment of toxoplasmosis is advisable to prevent schizophrenia. Also, screening of schizophrenic patients for chronic toxoplasmosis and the fore mentioned parameters is recommended for prediction of complications and presents a promising approach for prevention and management.","PeriodicalId":41408,"journal":{"name":"Parasitologists United Journal","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46990321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New record of Thubunaea pudica Seurat, 1914 (Spirurida: Physalopteridae) in lizard Trapelus mutabilis from Egypt","authors":"S. Harras, Rasha Elmahy","doi":"10.21608/puj.2019.13643.1046","DOIUrl":"https://doi.org/10.21608/puj.2019.13643.1046","url":null,"abstract":"Background: Studies on nematode taxa remain poorly described in cold blooded animals, with rareness of data on the helminth community of Egyptian ones, especially lizards. The available literatures are mostly restricted to ecological studies rather than descriptive ones. \u0000Objective: To identify and give full description for nematodes that inhabit the Desert Agama, Trapelus mutabilis (T. mutabilis) caught from El-Dabaa desert, Egypt. \u0000Material and Methods: Nineteen Agama lizards having the characteristic morphological criteria of T. mutabilis were dissected and examined for parasitic infection. Gastrointestinal nematodes were collected, fixed and identified using light microscopy. Those subjected for scanning electron microscopy (SEM) were dried, coated and examined. \u0000Results: Seven out of nineteen dissected lizards were found to be infected with the nematode Thubunaea pudica (T. pudica) (Family: Physalopteridae). They were collected from the stomach and small intestine of T. mutabilis. The main characteristics of adult T. pudica are: symmetrical anterior cephalic structure similar in both sexes, vulva is situated in the first tenth of the body, the tip of male tail ends beyond well-developed caudal alae with 32 true caudal papillae and two subequal stout spicules. \u0000Conclusion: The study added the first fully described details for T. pudica using both light and SEM. Moreover, T. mutabilis lizard represents a new host record for T. pudica in a new geographic locality El-Dabaa desert as there are no reports of this species recorded from Egypt.","PeriodicalId":41408,"journal":{"name":"Parasitologists United Journal","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48392380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of mini-FLOTAC method for diagnosing intestinal parasitic infections","authors":"Nada A. El-Nadi, A. Ahmed, N. Ahmed, Amany El-Laah","doi":"10.21608/puj.2019.13212.1045","DOIUrl":"https://doi.org/10.21608/puj.2019.13212.1045","url":null,"abstract":"Background:  Intestinal parasitic infections (IPIs) are widely distributed throughout the world and have been identified as one of the most significant causes of illnesses and diseases. Accurate diagnosis is essential for proper management and to guide the design, implementation and monitoring of programs for community control of infectious diseases. \u0000Objective: To evaluate and compare mini-FLOTAC technique with the widely used formol-ethyl-acetate concentration method (FECM) in IPIs detection. \u0000Material and Methods: One hundred fecal samples were randomly collected from different laboratories. All samples were microscopically examined using mini-FLOTAC and FECM. Iodine and modified Zeil-Neelsen stains were used to confirm the presence of protozoa cysts, and oocysts of Cryptosporidium spp. and C. cayetanensis, respectively. \u0000Results: About two thirds of samples (68%) were positive; 70.6% (48/68) contained only one parasitic infection by at least one method. Generally, the most frequent was Cryptosporidium spp. 35.3% (24/68) followed by E. histolytica/dispar 23.5% (16/68) and G. intestinalis 14.7% (10/68). It was observed that mini-FLOTAC detected the highest number of helminthes infections (100% sensitivity) in contrast to 41.1% for protozoa whereas FECM was the most sensitive approach for protozoa infections (98.2% sensitivity) in contrast to 68.7% for helminthes. \u0000Conclusion: Mini-FLOTAC is a safe rapid device for microscopic examination of stool samples with high sensitivity, affordability, and appropriateness of diagnosis in resource-limited settings where IPIs are widespread","PeriodicalId":41408,"journal":{"name":"Parasitologists United Journal","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42857603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preneoplastic proliferative changes induced by experimental blastocystosis","authors":"M. M. Ahmed, F. Habib, G. Saad, Heba El Naggar","doi":"10.21608/puj.2019.11959.1041","DOIUrl":"https://doi.org/10.21608/puj.2019.11959.1041","url":null,"abstract":"Background: Studying the pathogenic potential of Blastocystis spp. by in vitro and in vivo experimental studies led to suspicions concerning its role in development of cancer colon. Still, this hypothesis remains under investigations. \u0000Objective: To investigate the pathology induced in the gut of mice inoculated with Blastocystis spp. isolates derived from patients with and without colorectal carcinoma (CRC). \u0000Subjects and Methods: Seven Blastocystis spp. isolates were derived from patients with CRC, six from non-CRC patients with symptomatic blastocystosis and six from non-CRC asymptomatic Blastocystis spp. carriers. Isolates were used to induce experimental blastocystosis in three groups of three-weeks-old BALB-c mice: GI was inoculated by CRC isolates; GII by symptomatic non-CRC isolates; and GIII by non-CRC asymptomatic isolates. Always, one clinical isolate was used to infect one mouse. Each group contained one negative control mouse inoculated with parasite-free culture medium, kept under the same conditions. \u0000Results: Histopathological examination of sections of intestine of all inoculated mice in the three groups showed positive infection with parasites seen only in the cecum and colon, no parasites were seen in the small intestine. Inflammatory cells infiltrations were detected in mice of the three groups with varying degrees. Vacuolar forms of Blastocystis spp. were seen infiltrating the submucosa in sections from mice in GI (4 mice) and GII (2 mice) but not in GIII. The significant difference in the pathologic changes induced in the intestine of mice in the three groups was observed being more severe with polypoid formation in mice in GI (4 mice) than in GII (1 mouse). \u0000Conclusion: Blastocystis spp. isolates associating CRC differ in their proliferative and invasive pathogenic capabilities than symptomatic isolates. Asymptomatic Blastocystis spp. are non-invasive organisms causing only mild inflammatory response in the large intestine of experimentally infected animals","PeriodicalId":41408,"journal":{"name":"Parasitologists United Journal","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42988331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastrointestinal helminths of lizards (Reptilia: Squamata) from Egypt","authors":"Rasha Elmahy, S. Harras","doi":"10.21608/puj.2019.13809.1048","DOIUrl":"https://doi.org/10.21608/puj.2019.13809.1048","url":null,"abstract":"Background: Despite the fact that Egypt contains a large number of lizard species, yet there is little knowledge recorded regarding the helminth fauna infecting this group of hosts. A parasitological study on gastrointestinal helminths of lizards was carried out during Summer (August) and Autumn (September and October), 2014 and 2015, respectively. \u0000Objective: This study aims to update information on helminth parasites that infect lizards in Egypt. \u0000Material and Methods: Seven species of lizards, Pseudotrapelus sinaitus Heyden, 1827; Trapelus mutabilis Merrem, 1820 (Agamidae); Tarentola mauritanica mauritanica Linnaeus, 1758 (Phyllodactylidae); Tropiocolotes tripolitanus Peters, 1880 (Gekkonidae); Acanthodactylus boskianus Daudin, 1802 (Lacertidae); Chamaeleo africanus Laurenti, 1768 (Chamaeleonidae); and Varanus niloticus Linnaeus, 1766 (Varanidae), were collected from several parts of Egypt. These hosts were dissected and examined for gastrointestinal helminth. The collected helminths were fixed in 70% ethanol, stained with carmine and examined by using an Olympus CX31 microscope and a Zeiss Stemi 2000-C microscope. \u0000Results: The total prevalence of infection with helminths was 35.9%. The study recorded 16 species of helminths recognised as: six species of digenea [Prosthodendrium obtusum (Looss, 1896) Bhalerao, 1936, Pleurogenoides tener (Olsson, 1876) Travassos, 1921, Anchitrema sanguineum (Sonsino, 1894) Looss, 1899, Cyclorchis varani Price, 1936, Mesostephanus milvi Yamaguti, 1939 and Haplorchis pumilio (Looss, 1896) Looss, 1899], four species of cestodes [three adults, Oochostrica mutabili Morsyet al., 2013, Duthiersia fimbriata Diesing, 1854 and one unidentified cestode and one tetrathyridia of Mesocestoides spp.] and six species of nematodes [Parapharyngodon micipsae Seurat, 1917, Pharyngodon inermicauda Baylis, 1923, Abbreviata leptosome Gervais, 1848, Thubunaea pudica Seurat, 1914, Tanqua tiara (von Linstow, 1879) Blanchard, 1904 and Spinicauda sonsinoi (Linstow, 1894) Travassos, 1920]. \u0000Conclusion: This study documents 10 new host and 10 new locality records in Egypt and distinguishes between studied material and reported descriptions. These findings add significantly to the present information on helminths infecting lizards in Egypt.","PeriodicalId":41408,"journal":{"name":"Parasitologists United Journal","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48031686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel impact of Boswellia serrata on Blastocystis spp. infected mice","authors":"R. Sarhan, G. Saad, H. M. E. Eldin, M. Hetta","doi":"10.21608/puj.2019.12062.1042","DOIUrl":"https://doi.org/10.21608/puj.2019.12062.1042","url":null,"abstract":"Background: The susceptibility of Blastocystis spp.to standard antimicrobials is not clear. The development of resistant strains against the recommended drugs has evoked the importance of using an alternative medicine. Metronidazole constitutes a mainstay and is considered the first line for treatment, yet, it is complicated with many drawbacks. The demand for finding alternatives introduced nitazoxanide (NTZ) and natural products to provide successful new regimens for treatment and to avoid resistant infections. \u0000Objective: The present study was conducted to evaluate the anti-Blastocystis effects of Boswellia serrata compared to NTZ on experimentally infected mice. \u0000Material and Methods: Three groups of BALB-c mice were used: untreated control group (G1); infected mice treated with NTZ (G2); infected mice treated with B. serrata (G3). Histopathological examination of colonic epithelium and immunohistochemical assessment was done for detection of TNF-α in the two groups of mice treated with B. serrata in comparison to those treated with NTZ. \u0000Results: The test appraised the effect of B. serrata which succeeded in maintaining the intact surface epithelium and goblet cells. The mononuclear infiltrations were markedly decreased in the lamina propria and appeared as small aggregates at the base of the crypts. The submucosa showed marked reduction of inflammatory cells. Occasional intraepithelial lymphocytes were detected in-between epithelial cells. The negative Periodic Acid-Schiff (PAS) reaction detected in the intestinal crypts was comparable to NTZ treatment. Surpassing NTZ, B. serrata-treated group showed an apparently less positive reaction to TNF-α in the cells of the submucosa and lamina propria, while NTZ effect was restricted only to the submucosa. \u0000Conclusion: This natural product can offer an alternative therapy for use instead of or concurrently with the conventional anti-Blastocystis treatment.","PeriodicalId":41408,"journal":{"name":"Parasitologists United Journal","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47396042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro assessment of Schistosoma mansoni cercaricidal activities of Solanum nigrum and Callistemon citrinius leaves extracts and cercarial genetic changes by RAPD-PCR","authors":"G. Sadek, N. Harba, M. Faheem","doi":"10.21608/PUJ.2019.7468.1029","DOIUrl":"https://doi.org/10.21608/PUJ.2019.7468.1029","url":null,"abstract":"Abstract: Background: Schistosomiasis is contracted by exposure to fresh water containing cercariae that develop into adult worms after penetration of human skin. Interruption of schistosomiasis vital cycle by elimination of cercariae may enhance methods of transmission control. Objective: To evaluate the vitro effect of methanol extracts of Solanum nigrum ( S.nigrum) and callistemon citrinus (C. citrinus) leaves on Schistosoma mansoni cercarial genetic makeup by random amplification of polymorphic DNA-Polymerase chain reaction (RAPD-PCR). Material and methods: The effect different concentrations of both plants extracts on cercarial morphology and mortality was observed with different lethal concentrations (LC). Also, assessment of DNA change in exposed S.mansoni cercariae to LC50 of both plants in comparsion with non-exposed ones by RAPD-PCR assay was investigated. Cercariae were divided into three groups: group A: control non-exposed cercariae; group B: cercariae exposed to S.nigrum; and group C: cercariae exposed to C.citrinus. Results: The cercaricidal potency of tested extracts was concentration-dependent. The cercaricidal toxicity of S. nigrum extracts was 1.2 times higher than that of C.citrinus(LC90 values were 50 mg/L and 60 mg/L, respectively). RAPD-PCR revealed different band polymorphism patterns for each primer used and cercariae exposed to S.nigrum revealed a higher number of band polymorphism (20 bands) than that obtained by cercariae exposed to C.citrinus (16 bands) which were different from those of control group reflecting the genetic variability among the groups studies. Conclusion: C.citrinus and S.nigrum are effective cercaricidal agents that can be utilized to minimize water transmission of schistosomiasis. Also, RAPD-PCR is useful for examining the genetic polymorphism of schistosomal cercariae induced by plants extracts, and assessment of genetic of damage of drug development fields.","PeriodicalId":41408,"journal":{"name":"Parasitologists United Journal","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46627030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular monitoring of the therapeutic effect of Albendazole on Ascaris lumbricoides and Ancylostoma duodenale infected children using conventional multiplex PCR","authors":"S. Yahia, Howayda S. F. Moawad, T. Farag, S. Mohammad","doi":"10.21608/PUJ.2019.10309.1033","DOIUrl":"https://doi.org/10.21608/PUJ.2019.10309.1033","url":null,"abstract":"ABSTRACT Background: Globally, many individuals are infected with soil-transmitted helminthes (STHS)with majority occurring in tropical and subtropical regions of the world. Albendazole (ADZ) is a broad-spectrum anthelmintic used efficiently for STHs control. Upgrading the assessment of ADZ efficacy is important to confirm that drug resistance has not emerged. Objective: To assess the therapeutic efficiency of ADZ in both A.duodenale infections by conventional multiplex PCR. Subjects and Methods: Stool specimens from 191 boys  and 123 girls, aged from 2to3 years were screened by saline wet mount and iodine stained smears and cellophane thick smears (Keto-Katz technique). All positive cases were given a single oral dose of 400 mg ADZ than 2 weeks later new stool samples were collected and subjected to multiplex PCR. Before medication, anemia assessment (figure prick capillary blood sample) was performed. Results: Prevalence of infection with A.lumbricoides and A.duodenale was 20.7% and 5.4%, respectively. Parasitic infections were more prevalent in age group 7-13 years (59%) than in 2-6 years (41%) respectively. Boys were slightly more affected than girls (52.6% versus 47.4%). Prevalence of parasitic infections among cases living in rural areas proved to higher than those living in urban areas (65.4% versus 34.6%). Examination  for associated anemia showed that 35.9% of infected cases were anemic (Hb level < 11.5 mg/dl) versus 9.7% in non-infected cases. Diarrhea and colic were more prevalent in infected cases (39.7% and 62.8%, respectively) than in those that were non-infected (5.5% and 8.9%, respectively). The therapeutic efficacy of ADZ resulted in a cure rate of 93.8% and 88.2% for A.lumbricoides and A.duodenal infections, respectively; with an egg reduction rate (ERR)of 96.1% and 91.2%, respectively. The multiplex PCR sensitivity was 100% for detection of both worms; the specificity was 96.8% and 93.8%, respectively. With diagnostic accuracy of 96.9% and 94.1%, respectively. Conclusion: Multiplex PCR was useful for measurement of the therapeutic efficacy of ADZas an anthelminthic drug.","PeriodicalId":41408,"journal":{"name":"Parasitologists United Journal","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42097929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Theodor Bilharz and a life trip to Egypt","authors":"N. El-Dib","doi":"10.21608/PUJ.2019.10929.1036","DOIUrl":"https://doi.org/10.21608/PUJ.2019.10929.1036","url":null,"abstract":"abstract: Theodor Billharz, the German professor born in Sigmaringen in 1825, is one of the eminent professors in the history of Parasitiology and Tropical Medicine. He came to Egypt as an assistent of professor Griesinger in the year 1850, and was fascinated with the country, to the degree that he studied Arabic and hieroglyphic languages in order to understand Egypt and Egyptians. He was assigned to work in Kasr Al Ainy hospital in Cairo where he served the patients and lectured the midecal students. During his work, he detected the blood fluke Distomum haematobium (that was later called Schistiosoma), the causative agent of hematuria and severe diseases among the Egyptians since ancient time. This discovery is considered a very important advancement in the recongnition of the diseases and its control. Billharz died in Egypt and was buried in Cairo. The Ministry of Health in Egypt honored him by establishing the institute of Theoder Billharz, for Schistosomiasis research.","PeriodicalId":41408,"journal":{"name":"Parasitologists United Journal","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45464625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}