Almas Dwi Khairana, R. Raissa, W. Riawan, S. Suharti, H. Susanto, Aulanni’am Aulanni’am
{"title":"Giving of Diethylnitrisamine and Carbon Tetrachloride on Histological Appearance of Rat Kidney (Rattus Norvegicus)","authors":"Almas Dwi Khairana, R. Raissa, W. Riawan, S. Suharti, H. Susanto, Aulanni’am Aulanni’am","doi":"10.36590/jika.v4i1.242","DOIUrl":"https://doi.org/10.36590/jika.v4i1.242","url":null,"abstract":"Diethylnitrosamine (DEN) is a metabolic product of various foods and beverages in which there are preservatives in the form of nitrate and nitrite. Nitrosamines are found in various products such as alcoholic beverages, processed meats, cigarettes, and cosmetic products. DEN is toxic and carcinogenic to organs such as the liver, lungs, kidneys, skin, stomach, and blood. In addition to giving DEN compounds, there are also CCl4 compounds as tumor promoter agents known as genotoxic substances that can increase the risk of genetic errors and stimulate cells to become malignant neoplasms. Administration of DEN and CCl4 induction can damage various organs of the body, one of which is the kidney. In a healthy body, angiogenesis plays a role in wound healing and the formation of new tissue. However, angiogenesis also contributes to carcinogenesis or the uncontrolled growth of cancer cells, and is malignant when the body is contaminated with toxic substances. Therefore, to determine the effect of the administration of DEN and CCl4 observations were made using the immunohistochemical method, to see differences in the histology of the kidneys of experimental animals, the positive control group, and the negative control group based on the VEGF angiogenesis factor. From these results, there are significant differences. In the negative group, there was no necrosis and high-value VEGF expression, but in the positive group, there was necrosis and a decrease in the value of VEGF expression compared to the negative control group.","PeriodicalId":408003,"journal":{"name":"Jurnal Ilmiah Kesehatan (JIKA)","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125452503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sensory Characteristics and Nutrient Content of Food Bar with Flour and Pumpkin Seed Substitution","authors":"M. Amalia, N. Nuryani, B. Santoso","doi":"10.36590/jika.v4i1.271","DOIUrl":"https://doi.org/10.36590/jika.v4i1.271","url":null,"abstract":"The development of snack bar products from fruit and pumpkin seeds can provide health benefits. The purpose of this study was to assess the sensory characteristics and nutritional value of a food bar with flour and pumpkin seeds substitution. The research method used a completely randomized design with 3 treatments with different formulations of pumpkin flour and pumpkin seeds. Parameters observed included color, aroma, taste, texture, and proximate tests including moisture, protein, fat, ash, and carbohydrate content. The data from the level of preference test variables would be analyzed using the t-test. The results showed the organoleptic analysis of the highest color at F4 (2,55), preferred aspect taste at F1 (3,48), aroma at F1 (3,55), and texture at F2 (3,84). Proximate analysis was showed the highest in water content at F2 (20,14%), the ash content in F4 (2,77 g), protein content in F1 (18,65 g), fat content in F1 (22,48 g), the fiber content in F2, and carbohydrate content in F4 (42,15 g). The conclusion that there were significant differences in the sensory test of color, taste, and aroma from four food bar formulas with flour and pumpkin seed substitution, while the density (texture) of the food bar formulas was not significantly different from each other.","PeriodicalId":408003,"journal":{"name":"Jurnal Ilmiah Kesehatan (JIKA)","volume":"197 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127939334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ade Wira Listrianti Latief, Sri Novianti Bahar, R. Maharja, Rostati Rostati, Muhammad Irsyad
{"title":"Associated Factors Work Fatigue on Farmers","authors":"Ade Wira Listrianti Latief, Sri Novianti Bahar, R. Maharja, Rostati Rostati, Muhammad Irsyad","doi":"10.36590/jika.v4i1.240","DOIUrl":"https://doi.org/10.36590/jika.v4i1.240","url":null,"abstract":"Fatigue is a common complaint experienced by the working community. The term fatigue usually denotes a different condition for each individual, but all of them lead to a loss of efficiency and a decrease in work capacity and endurance. Fatigue is classified into two types namely, muscle fatigue and general fatigue. The purpose of this study was to determine the factors associated with work fatigue in farmers in Amessangngeng Village, Donri-Donri District, Soppeng Regency. This study used a quantitative research method with a cross-sectional approach. The population of this study was farming groups in Ammessangeng Village, Donri-Donri District, Soppeng Regency with 43 farmers. This study used total sampling. The results showed that there was a relationship between age (p-value=0,024), length of work (p=0,026), years of service (p-value=0,008), and work attitude (p-value=0,013) with fatigue among farmers. It is hoped that farmers will pay more attention to their lifestyle and work methods so that when they work they do not experience work fatigue.","PeriodicalId":408003,"journal":{"name":"Jurnal Ilmiah Kesehatan (JIKA)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129957044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Eliza, Darlita Aprilianti, Yunita Nazarena, Terati Terati, Sumarman Sumarman
{"title":"Lakuto on Blood Glucose Level in Type 2 Diabetes Mellitus","authors":"E. Eliza, Darlita Aprilianti, Yunita Nazarena, Terati Terati, Sumarman Sumarman","doi":"10.36590/jika.v4i1.232","DOIUrl":"https://doi.org/10.36590/jika.v4i1.232","url":null,"abstract":"Diabetes Mellitus is a chronic disease characterized by hyperglycemia and glucose intolerance in the blood because the pancreas is unable to produce insulin. The risk factors that led to diabetes mellitus are reversible and irreversible. The study was aimed at recognizing the effect that pumpkin and tomato pudding (lakuto) have on decreasing blood glucose levels in type 2 diabetesmellitus in Puskesmas Padang Selasa Palembang. It is a quantitative research using quasi-experiment design with pretest and posttest with two groups design. The subjects were mostly 61-70 years old and female. Average levels of blood glucose before treatment are 329,33 mg/dl in the treatment group and 314,07 mg/dl in the control groups. Whereas the average blood glucose level after treatment was 301,43 mg/dl in the treatment group and 304,00 mg/dl in the control groups. The result showed the effects of pumpkin and tomato pudding (lakuto) on blood glucose levels in diabetes mellitus type 2 in Puskesmas Padang Selasa Palembang (p-value=0,000). This suggests that pumpkin and tomato pudding (lakuto) may lower blood glucose levels in patients with type 2 diabetes mellitus.","PeriodicalId":408003,"journal":{"name":"Jurnal Ilmiah Kesehatan (JIKA)","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130952000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sleep Quality, Stress Level, Physical Activity, and Food Consumption with Nutritional Status","authors":"Nurhidayah Syarifuddin, D. Briawan, Tiurma Sinaga","doi":"10.36590/jika.v4i1.238","DOIUrl":"https://doi.org/10.36590/jika.v4i1.238","url":null,"abstract":"Obesity is one of the nutritional problems in Indonesia. Meanwhile, based on data from Basic Health Research in 2018, the prevalence of overweight was 13.6% and obesity was 21,8%. This study aimed to analyze sleep quality, stress, physical activity, and food consumption with nutritional status. A cross-sectional study design was applied with 60 subjects aged 20-30 years old selected by cluster random sampling method. Characteristics of subjects, sleep quality, stress levels, physical activity, and food consumption data were collected through interviews by structured questionnaires and direct measurements. The results showed no significant between age, gender, allowance, food expenditure, physical activity, and food diversity with nutritional status (p>0,05). In contrast, sleep quality and stress levels were significant to nutritional status (p<0,05), and stress level was the risk factor for the obesity incidence, OR= 6,2 [95% CI 1,9-20,3]. Thus, stress levels are a risk factor that affects individual nutritional status.","PeriodicalId":408003,"journal":{"name":"Jurnal Ilmiah Kesehatan (JIKA)","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130679103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dukungan Keluarga dengan Pengetahuan dan Sikap pada Penderita Hipertensi","authors":"Agus Susanto, Heni Purwantiningrum","doi":"10.36590/jika.v4i1.224","DOIUrl":"https://doi.org/10.36590/jika.v4i1.224","url":null,"abstract":"Hipertensi merupakan penyakit yang ditandai dengan kenaikan tekanan darah di atas normal. Penyakit ini memerlukan tindakan pengobatan secara berkelanjutan dan perubahaan perilaku yang lebih sehat. Faktanya banyak penderita hipertensi tidak patuh minum obat ataupun enggan untuk memperbaiki pola makan dan gaya hidup. Beberapa faktor penyebabnya adalah berhubungan dengan kurangnya dukungan keluarga, tingkat pengetahuan dan sikap penderita hipertensi. Penelitian ini bertujuan untuk menganalisis tentang dukungan keluarga, pengetahuan dan sikap penderita hipertensi dalam mengobati penyakit hipertensi. Penelitian ini adalah penelitian cross-sectional yang dilaksanakan di Kota Tegal. Sampel penelitian adalah sebesar 200 penderita hipertensi yang telah didiagnosis lebih dari enam bulan dan telah menjalani terapi hipertensi secara medis. Data penelitian dikumpulkan dengan menggunakan instrumen kuesioner. Penyajian data dilakukan secara deskriptif dan tabulasi silang. Temuan lapangan menunjukkan bahwa 87% subjek berasal dari keluarga yang mendukung, 48% memiliki pengetahuan yang kurang baik dan 77% memiliki sikap yang sangat baik. Nilai p dari uji statistik korelasi dukungan keluarga dengan pengetahuan dan sikap adalah 0,000 dan 0,007. Hasil temuan lapangan tersebut menunjukkan ada hubungan signifikan antara dukungan keluarga dengan pengetahuan dan sikap penderita hipertensi (nilai p=<0,05). Dukungan keluarga memiliki peran penting dalam meningkatkan pengetahuan dan pembentukan sikap penderita hipertensi.","PeriodicalId":408003,"journal":{"name":"Jurnal Ilmiah Kesehatan (JIKA)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130467834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pengetahuan Gizi dan Persepsi terhadap Perilaku Konsumsi Makanan Pemicu Kanker","authors":"Indah Ditasari, Ditia Fitri Arinda","doi":"10.36590/jika.v4i1.214","DOIUrl":"https://doi.org/10.36590/jika.v4i1.214","url":null,"abstract":"\u0000Salah satu cara untuk menghindari masalah penyakit degenaratif atau penyakit tidak menular ini yaitu memiliki perilaku makan yang sehat. Penelitian ini bertujuan untuk melihat adakah hubungan antara pengetahuan tentang gizi dengan persepsi terhadap perilaku konsumsi makanan pemicu kanker pada mahasiswa Universitas Sriwijaya yang dikontrol oleh variabel confounding. Pada penelitian ini pendistribusian menggunakan google form di 238 mahasiswa/I yang diacak menggunakan metode random sampling. Adapun variable yang paling dominan berhubungan dengan perilaku konsumsi makanan pemicu kanker pada mahasiswa Universitas Sriwijaya adalah variable pesepsi 0,021 (Pvalue < 0,05) setelah dikontrol oleh variabel confounding pengetahuan dan pengaruh teman. Penting adanya upaya pencegahan seperti peningkatan pengetahuan gizi pada mahasiswa/i agar pengetahuannya meningkat serta persepsinya juga meningkat.\u0000\u0000\u0000 \u0000","PeriodicalId":408003,"journal":{"name":"Jurnal Ilmiah Kesehatan (JIKA)","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127555118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}