N. J. Kumar, Jaichandran V. Venkatakrishnan, B. George, M. Sivaprakasam, Jagadeesh Kumar V
{"title":"Visual Feedback Enabled Training Mannequin For Ophthalmic Blocks: an Evaluative Study","authors":"N. J. Kumar, Jaichandran V. Venkatakrishnan, B. George, M. Sivaprakasam, Jagadeesh Kumar V","doi":"10.1109/CIBEC.2018.8641833","DOIUrl":"https://doi.org/10.1109/CIBEC.2018.8641833","url":null,"abstract":"Recently, a training mannequin suitable for ophthalmic blocks has been developed. It provides a new feature of visual feedback to the trainee. A validation of the efficacy of this training system with needle angle visualization, ocular structure proximity, and procedural warning features was conducted in an evaluative study with 41 participants; 21 post graduate trainees and 20 ophthalmic consultants from a tertiary ophthalmic care facility in Chennai, India. The participant’s performance was evaluated and analyzed using an appropriate scoring scheme in two sessions with and without visual feedback. The participants were also requested to provide feedback on the anatomical likeness and usage. A two tailed signed rank Wilcoxon test verified the statistical significance of the visual feedback (Pz(4.55, 0.05)= 0.9999, $Plt $0.001). The mean score of the participants showed an increase 58.86% and 25.5% for graduate trainee and consultants respectively and a mean reduction of 85.41% in the warning indications provided was also substantiated the efficacy of the visual feedback.","PeriodicalId":407809,"journal":{"name":"2018 9th Cairo International Biomedical Engineering Conference (CIBEC)","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115996266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Image Reconstruction using Self-Prior Information for Sparse-View Computed Tomography","authors":"Mona Selim, E. Rashed, M. Atiea, H. Kudo","doi":"10.1109/CIBEC.2018.8641789","DOIUrl":"https://doi.org/10.1109/CIBEC.2018.8641789","url":null,"abstract":"The contradiction between the great benefits of computed tomography (CT) in diagnosis and the risk of redundant CT scan on the patient health, make the researchers compete developing image reconstruction methods for low-dose CT. Sparse-view CT is a common technique in radiation dose minimization. Due to the streak artifacts that result while using the analytical reconstruction method with sparse-view CT, several iterative reconstruction methods have presented to produce high image quality. In this work, we introduce extracting the prior information incorporated in the reconstruction method during the process of reconstruction itself, in contrast to the other related methods that prepare the prior information in advance. The proposed technique is divided into two main steps. The first step is the construction of self-prior information. The second step is incorporating this produced information into the reconstruction process. The performance of the proposed method is evaluated using simulation and synthetic real data. Results show that the proposed technique produce high image quality.","PeriodicalId":407809,"journal":{"name":"2018 9th Cairo International Biomedical Engineering Conference (CIBEC)","volume":"155 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125964276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samar M. Abd El-fattah, Sherif H. El-Gohary, Noha Hassan
{"title":"3D Model Construction and Analysis of Female Genital Organs Using Monte Carlo Simulation for Early Detection of Cervical Intraepithelial Neoplasia","authors":"Samar M. Abd El-fattah, Sherif H. El-Gohary, Noha Hassan","doi":"10.1109/CIBEC.2018.8641808","DOIUrl":"https://doi.org/10.1109/CIBEC.2018.8641808","url":null,"abstract":"In this paper, Monte Carlo simulations of light propagation in realistic MRI based anatomical 3D models of the female genital organs, which are considered heterogeneous media, are presented. Three models representing a normal case with no cervical abnormalities and two abnormal cases representing early and late stage cervical cancer were used in the computations. The magnitude and the distribution of light intensity through the three models are computed for different sizes of the region of interest encompassing parts of structures surrounding the cervix, different penetration depths and different placements of the light source (trans-vaginal and transrectal). Results show that trans-rectal simulations are as useful as trans-vaginal simulations and that light absorption is highly dependent on the size and location of the cervical tumor with respect to the light source and the penetration depth with respect to the beginning of the cervix. The visualization of the light intensity maps in the cervix, surrounding organs and cervical tumors may provide insights into photodynamic therapy planning as well as into photoacoustic imaging of cervical cancer.","PeriodicalId":407809,"journal":{"name":"2018 9th Cairo International Biomedical Engineering Conference (CIBEC)","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116085819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Kishk, Asmaa Elzizy, D. Galal, El Razek, Esraa Fawzy, Gehad Ahmed, M. Gawish, S. Hamad, M. El-Hadidi
{"title":"A Hybrid Machine Learning Approach for the Phenotypic Classification of Metagenomic Colon Cancer Reads Based on Kmer Frequency and Biomarker Profiling","authors":"Ali Kishk, Asmaa Elzizy, D. Galal, El Razek, Esraa Fawzy, Gehad Ahmed, M. Gawish, S. Hamad, M. El-Hadidi","doi":"10.1109/CIBEC.2018.8641805","DOIUrl":"https://doi.org/10.1109/CIBEC.2018.8641805","url":null,"abstract":"Human Microbiome plays a critical role in health and the environment. Colorectal cancer (CRC) is the most common cause of death in many countries, and hence early diagnosis of CRC may help in increasing the survival rate. Tracking changes in the microbiome structure of human gut opens new gates towards the detection and prediction of the risk of CRC. Recently, machine learning became a powerful technique in many bioinformatics fields, one of which is metagenomics. Metagenomics is defined as the study of a collection of microbial genomes isolated directly and sequenced from its natural habitats. Applications of machine learning in metagenomics are numerous, among them are phenotype classification, taxonomic assignment, and sequence annotation. Phenotype classification is assigning a phenotypic class to each sample such as diseased or healthy, according to the available metadata. Phenotype classification in metagenomics is usually done on organism taxonomic units (OTU) tables extracted as a core step in the metagenomic analysis. On the other hand, Natural Language Processing (NLP) methods such as kmer frequency, can provide features for the machine learning model. In this study, we combined a biomarker profiling and a kmer frequency table approaches to classify colorectal cancer from metagenomic data.","PeriodicalId":407809,"journal":{"name":"2018 9th Cairo International Biomedical Engineering Conference (CIBEC)","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117140419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sameh Sherif, Y. Ghallab, A. Seddik, Hamdy Abdelhamid, Y. Ismail
{"title":"Impedance Analysis of Different Shapes of the Normal and Malignant White Blood Cells","authors":"Sameh Sherif, Y. Ghallab, A. Seddik, Hamdy Abdelhamid, Y. Ismail","doi":"10.1109/CIBEC.2018.8641788","DOIUrl":"https://doi.org/10.1109/CIBEC.2018.8641788","url":null,"abstract":"In this paper, a 3d numerical study for double shell leukemia cell impedance is presented. A capacitive sensing based technique is used to extract the cell’s Clausius-Mossotti factor. The spherical and non-spherical shapes are considered in this work. We found the impedance of non-spherical leukemia shape is higher than the spherical leukemia shape. Also, a full study of impedance for different shapes of normal and malignant white blood cell using numerical simulators is presented and discussed. Moreover, the location of the cell over the sensing electrodes is considered to extract the exact impedance value.","PeriodicalId":407809,"journal":{"name":"2018 9th Cairo International Biomedical Engineering Conference (CIBEC)","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131561816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mina A. Nagi, Nourhan A. Elbeheiry, Homam M. Shershira
{"title":"Simultaneous and Successive Three Dimensional Hydrodynamic Focusing in Flow Cytometer","authors":"Mina A. Nagi, Nourhan A. Elbeheiry, Homam M. Shershira","doi":"10.1109/CIBEC.2018.8641818","DOIUrl":"https://doi.org/10.1109/CIBEC.2018.8641818","url":null,"abstract":"Hydrodynamic focusing inside microfluidic devices has the main role in precisely directing the particles flow into a single stream carrying one particle at a time for cell sorting and medical diagnosis. In this paper two micro channel designs for focusing the sample flow in both the horizontal and vertical directions are presented. Using the proposed designs three dimensional (3D) focusing is achieved either simultaneously, where two pairs of cylindrical shaped horizontal and vertical side channels are located at same point, or successively by locating the vertical channels apart from the horizontal ones. A comparison between the two designs is presented regarding effect of vertical side channels location on focusing width, identity of focusing and ion concentration distribution inside the micro channel. Moreover the effect of different parameters on the focusing width and the concentration profile is investigated. Numerical simulation is performed using COMSOL multiphysics software.","PeriodicalId":407809,"journal":{"name":"2018 9th Cairo International Biomedical Engineering Conference (CIBEC)","volume":"123 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124744300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Efficient Computer Aided Detection for 3D Neurostructural Reconstruction of Magnetic Resonance Images","authors":"M. Mabrouk, S. Marzouk, Heba M.Afify","doi":"10.1109/CIBEC.2018.8641798","DOIUrl":"https://doi.org/10.1109/CIBEC.2018.8641798","url":null,"abstract":"The comprehensive framework for analyzing brain images performs by the integration between three dimensional (3D) reconstruction and neuroimaging approach to realize brain diseases progressions. Computer Aided Detection (CAD) technology has numerous achievements in brain tumor processing for improving the quality of brain visualization to support neuroradiologists without the need for surgical biopsy or resection. Despite the advance in the radiological diagnosis of neuroimaging data, magnetic resonance imaging (MRI) has some restrictions that related to human errors and incomplete interpretation of brain tumor regions. Also, MRI scan produces 2D images of the brain that was very difficult to handle different types of tumor. Therefore, many algorithms are used computer-based classification to accurately distinguish between tumor regions from the brain MR images that provided an early diagnosis of brain diseases. This study investigated the CAD system using 3D image reconstruction of MR brain and tumor structures efficiently under MATLAB platform to recognize the location, volume, and type of brain tumors. In addition, the proposed system applied the Fuzzy C-Means (FCM) algorithm as image segmentation and support vector machine (SVM) as image classification for tumor detection of MR brain images. Results confirmed that this 3D model depicted an advanced view for estimating of human brain diseases.","PeriodicalId":407809,"journal":{"name":"2018 9th Cairo International Biomedical Engineering Conference (CIBEC)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124755840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fatma S. Ibrahim, Mohamed N. Saad, A. M. Said, Hesham F. A. Hamed
{"title":"Haplotype Block Partitioning for NARAC Dataset Using Interval Graph Modeling of Clusters Algorithm","authors":"Fatma S. Ibrahim, Mohamed N. Saad, A. M. Said, Hesham F. A. Hamed","doi":"10.1109/CIBEC.2018.8641758","DOIUrl":"https://doi.org/10.1109/CIBEC.2018.8641758","url":null,"abstract":"Recently, genome-wide association studies (GWAS) depend on haplotype blocks rather than individual single-nucleotide polymorphism (SNP) because they are more powerful in association analysis. The computation of a genotyped dataset is considered as a challenge because of its massive size and its complexity. Several algorithms have been proposed for partitioning the genotype data into haplotype blocks. Most existing algorithms part genotype data into small blocks and ignore the middle regions of low linkage disequilibrium (LD) between strong related SNPs. Other methods produce redundant blocks by identifying haplotype block if all inside SNPs associated with the start and end SNPs of the block. This study has adopted the latest haplotype block partitioning method that based on the interval graph modeling of clusters algorithm. The proposed algorithm was applied on the North American Rheumatoid Arthritis Consortium (NARAC) dataset and then compared to confidence interval test (CIT), four-gamete test (FGT), and the solid spine of linkage disequilibrium (SSLD) methods. The dataset is preprocessed, and missing SNPs are imputed. This study demonstrates the distinctions between haplotype block partitioning methods and detects the haplotype blocks for NARAC dataset. The comparative study gives a better understanding of each method and produces different outcomes with different parameters.","PeriodicalId":407809,"journal":{"name":"2018 9th Cairo International Biomedical Engineering Conference (CIBEC)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128971437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Enhanced Hybrid Model for Skin Diagnosis Using Deep Convolution Neural Network","authors":"D. Shoieb, S. Youssef","doi":"10.1109/CIBEC.2018.8641806","DOIUrl":"https://doi.org/10.1109/CIBEC.2018.8641806","url":null,"abstract":"Melanoma is the deadliest form of skin cancer. Unfortunately, Skin cancer can’t be identified by visual examination. So, there is a call for an automated model which assists dermatologists in early diagnosis of skin cancer and help remote patient to save their life by remote diagnosis. This paper introduces an enhanced expert computer-aided model for skin diagnosis using deep learning. The proposed region of interest (ROI) segmentation is done by integrating both color and texture properties for the skin in both spatial and frequency domains. Then, the convolution neural network (CNN) is used for extracting all the possible discriminating features. Experiments have been conducted on various large datasets to demonstrate the efficiency of the proposed model. The experimental results show an outstanding performance in the terms of sensitivity, specificity and accuracy compared with others in literature.","PeriodicalId":407809,"journal":{"name":"2018 9th Cairo International Biomedical Engineering Conference (CIBEC)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130477963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}