Egyptian Journal of Dermatology and Venereology最新文献_第7页

Impact of childhood atopic dermatitis on family: correlation with disease severity 儿童特应性皮炎对家庭的影响：与疾病严重程度的相关性

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Egyptian Journal of Dermatology and Venereology Pub Date : 2022-01-01 DOI: 10.4103/ejdv.ejdv_1_21

Azza Abdel-Maguid, Esraa Abd El Salam, H. Gaber

{"title":"Impact of childhood atopic dermatitis on family: correlation with disease severity","authors":"Azza Abdel-Maguid, Esraa Abd El Salam, H. Gaber","doi":"10.4103/ejdv.ejdv_1_21","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_1_21","url":null,"abstract":"Background Atopic dermatitis (AD) is a common skin disease that not only severely burdens patients but also their families and society. AD is a chronic inflammatory disease that is usually detected in childhood. Objectives We aim to evaluate the quality of life of parents of children with AD and to crosscheck it with the intensity of the disease. Patients and methods This is a cross-sectional study, where the data of parents of 100 children with AD were collected from the outpatient clinic of the Dermatology, Venereology, and Andrology Department, Assiut University Hospitals, from May 2017 to May 2019. Parents answered the validated Arabic version of the Dermatitis Family Impact (DFI) questionnaire. The disease severity was assessed using the SCORAD index. Results Families of children with severe dermatitis had quite high DFI scores (16.37±3.727) compared with the families of those with dermatitis of moderate intensity (12.10±3.356) and dermatitis of low intensity (8.50±0.707) (P<0.001). It was observed that the impact of dermatitis on families had a positive significant correlation with the degree of intensity of AD (P<0.001, r=0.658). The highest-scoring DFI domains were sleep time, followed by a feeling of tiredness, emotional stability, general life, household work, and expenditure. Conclusion AD directly affects the quality of life of patients’ parents, and the adverse effects on the quality of life are significantly correlated with the disease severity.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"42 1","pages":"40 - 44"},"PeriodicalIF":0.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49602067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Oxidant and antioxidant status in patients with female pattern hair loss with varying severity 不同程度女性型脱发患者的氧化剂和抗氧化状态

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Egyptian Journal of Dermatology and Venereology Pub Date : 2022-01-01 DOI: 10.4103/ejdv.ejdv_38_19

Fathia M Khattab, A. Al-Karamany

引用次数: 0

Perforating folliculitis in Down’s syndrome − a rare case report 唐氏综合征伴穿孔毛囊炎一例罕见病例报告

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Egyptian Journal of Dermatology and Venereology Pub Date : 2022-01-01 DOI: 10.4103/ejdv.ejdv_60_20

Aswath Rajan, V. Pai, P. Shukla

引用次数: 1

Downregulation of microRNA-520 in chronic plaque psoriasis microRNA-520在慢性斑块型银屑病中的下调

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Egyptian Journal of Dermatology and Venereology Pub Date : 2022-01-01 DOI: 10.4103/ejdv.ejdv_29_21

Rehab Naguib, A. El-Rifaie, ManarA Awad, L. Rashed

引用次数: 0

Trappin-2/Elafin and Clusterin serum levels in pemphigus vulgaris and correlation with the severity score: a case–control study 寻常型天疱疮患者血清Trappin-2/Elafin和Clusterin水平及其与严重程度评分的相关性:一项病例对照研究

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Egyptian Journal of Dermatology and Venereology Pub Date : 2022-01-01 DOI: 10.4103/ejdv.ejdv_7_21

Badran Aya, S. Rofaida, Abd-ElkaderS Alaa, Kamel Amira, A. Fatma, G. Ahmed

引用次数: 0

Antiphospholipid antibody syndrome presenting as pyoderma gangrenosum 抗磷脂抗体综合征表现为坏疽性脓皮病

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Egyptian Journal of Dermatology and Venereology Pub Date : 2022-01-01 DOI: 10.4103/ejdv.ejdv_12_21

M. Abdulla

引用次数: 0

Analyses of serum 25-hydroxyvitamin D levels and single nucleotide polymorphisms in the vitamin D receptor gene for acne vulgaris: a case–control study 寻常痤疮患者血清25-羟基维生素D水平和维生素D受体基因单核苷酸多态性分析:一项病例对照研究

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Egyptian Journal of Dermatology and Venereology Pub Date : 2022-01-01 DOI: 10.4103/ejdv.ejdv_14_21

O. Shaker, Mohammed Hassan M, Talal Abd El-Raheem, SaraM Yasen

引用次数: 1

Characterization of lipid profile in psoriasis, acne vulgaris, and androgenetic alopecia: a case–control study 牛皮癣、寻常痤疮和雄激素源性脱发的脂质特征:一项病例对照研究

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Egyptian Journal of Dermatology and Venereology Pub Date : 2021-07-01 DOI: 10.4103/ejdv.ejdv_26_20

S. Adel, G. Nassef, Mostafa M Ezzat, Marwa Khalaf, T. Abdelraheem

{"title":"Characterization of lipid profile in psoriasis, acne vulgaris, and androgenetic alopecia: a case–control study","authors":"S. Adel, G. Nassef, Mostafa M Ezzat, Marwa Khalaf, T. Abdelraheem","doi":"10.4103/ejdv.ejdv_26_20","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_26_20","url":null,"abstract":"Background Disturbed lipid metabolism may play a role in psoriasis pathogenesis. Relationship between lipids and acne has been studied, and significant dyslipidemic findings were reported. In androgenetic alopecia (AGA), the role of androgens is not fully established, and nonandrogenic mechanisms may be involved. Objective The aim was to study lipid profile in patients with psoriasis, acne, and AGA and its relation to severity for a possible role in the etiopathogenesis of these diseases. Materials and methods The study included 25 patients with psoriasis, where the severity of psoriasis was evaluated by psoriasis area and severity index score; 25 patients with acne, where the severity of acne was evaluated by Global Acne Grading System; 25 patients with AGA, who were evaluated by the Norwood-Hamilton scale for males and Ludwig scale for females; and 25 healthy controls. Detailed history, clinical examination, BMI, and laboratory estimation of serum lipids (cholesterol, triglycerides, low-density lipoprotein-cholesterol, and high-density lipoprotein-cholesterol) were performed for all paricipants. Results There was a significant increase in low-density lipoprotein in each of psoriasis, acne, and AGA groups as compared with controls (P<0.05). Cholesterol and triglycerides were significantly higher only in psoriasis compared with controls (P<0.05). High-density lipoprotein was significantly lower in patients with psoriasis, acne, and AGA in comparison with controls (P<0.05), and it was negatively related to severity in psoriasis and acne. Conclusion Psoriasis, acne, and AGA are associated with atherogenic lipid profile, being more prominent in psoriasis and not related to known atherosclerotic risk factors except obesity. Patients with psoriasis and less likely acne and AGA may be at risk of atherosclerosis and consequently cardiovascular disease (CVD).","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"41 1","pages":"91 - 96"},"PeriodicalIF":0.4,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44124072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does breastfeeding delay the onset of eczema in infants? 母乳喂养是否会延缓婴儿湿疹的发作?

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Egyptian Journal of Dermatology and Venereology Pub Date : 2021-07-01 DOI: 10.4103/ejdv.ejdv_47_20

M. Al'Abadie, Greg P. Beer, M. Al-Rubaye, Faris Oumeish, D. Abadie

{"title":"Does breastfeeding delay the onset of eczema in infants?","authors":"M. Al'Abadie, Greg P. Beer, M. Al-Rubaye, Faris Oumeish, D. Abadie","doi":"10.4103/ejdv.ejdv_47_20","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_47_20","url":null,"abstract":"Background Cow’s milk has been shown to contribute to flare-up of atopic dermatitis, whereas breastfeeding was thought to help reduce the severity of the flare-ups of the condition. Aim To investigate whether breastfeeding or cow’s milk (bottle formula) has an influence on the course of and onset of atopic dermatitis symptoms. Three feeding modalities were evaluated. These are ‘breastfed,’ ‘bottle-fed,’ or ‘breast and bottle-fed.’ Patients and methods Medical records from general practice of patients aged 2 years or less with diagnosis of eczema, atopic dermatitis, atopic eczema, and infantile eczema were reviewed. A cohort of 131 patients was divided into three categories: (a) breastfed, (b) bottle-fed, and (c) breast and bottle-fed. These data were studied according to the data recorded at the 6-week infant health checkup. The age of the child at their first eczematous diagnosis was then calculated in accordance with their date of birth. Result New eczema diagnosis showed a similar trend in ‘breast-fed’ babies; however, onset of eczema was significantly delayed in the ‘breast and bottle-fed’ group when compared with bottle-fed alone. Most bottle-fed babies (58% of patients) were diagnosed at 31–60 days, whereas most ‘breast and bottle-fed’ babies (56%) were diagnosed at 91–120 days (P≥0.0001). Conclusion Babies from the two groups (‘breast’ and ‘breast and bottle-fed’) experienced a delayed onset of their eczema compare with ‘bottle-fed’ infant group. Breastfeeding can delay the onset of atopic dermatitis.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"41 1","pages":"67 - 70"},"PeriodicalIF":0.4,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43535990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Assessment of serum amyloid A level and the severity of atopic dermatitis 血清淀粉样蛋白A水平与特应性皮炎严重程度的评估

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Egyptian Journal of Dermatology and Venereology Pub Date : 2021-07-01 DOI: 10.4103/ejdv.ejdv_27_19

Fathia M Khattab, H. Ibraheem

{"title":"Assessment of serum amyloid A level and the severity of atopic dermatitis","authors":"Fathia M Khattab, H. Ibraheem","doi":"10.4103/ejdv.ejdv_27_19","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_27_19","url":null,"abstract":"Background Serum amyloid A (SAA) is an acute-phase protein that activates immune cells and induces cytokines and chemokine. SAA levels in the blood have been reported to be elevated in case of inflammation, infections, neoplasia, and tissue injury. This study measured the SAA in patients with atopic dermatitis (AD) and evaluated the association between the severity of AD and their values. Patients and methods A total of 52 patients with AD (22 males and 30 females) were involved in our study. Subjects were characterized as having atopic eczema (eAD; n=25) extrinsic type AD or nonatopic (iAD; n=27) intrinsic AD by serum immunoglobulin E level. Serum soluble IL-2R (IL-2R) and SAA levels were measured. Results The serum SAA levels was detectable in all patients with AD, showing significantly higher levels (P=0.026) in the patients with eAD (207 pg/ml; 95% confidence interval: 172–242 pg/ml) compared with those with iAD (144 pg/ml; 95% confidence interval: 116–178 pg/ml). The serum SAA levels were significantly correlated with eosinophil counts and sIL-2R levels and showed a tendency to correlate with SCORAD index and serum immunoglobulin E levels. Conclusion These results suggest SAA level as a parameter of AD activity and may support its possible role in the pathogenesis of AD.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"41 1","pages":"71 - 74"},"PeriodicalIF":0.4,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44934923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0