Egyptian Journal of Dermatology and Venereology最新文献_第10页

Rare Solitary Naevus Lipomatosis Cutaneous Superficialis: Histopathology A Diagnostic Clue 罕见单发痣状脂肪病:组织病理学诊断线索

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Egyptian Journal of Dermatology and Venereology Pub Date : 2021-04-02 DOI: 10.3126/NJDVL.V19I1.35412

D. P. Thapa, Moushami Singh

引用次数: 0

Congenital Melanocytic Nevus and Fibroepithelioma of Pinkus: A Rare Type of Collision Tumor 先天性黑素细胞痣和纤维上皮瘤:一种罕见的碰撞瘤

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Egyptian Journal of Dermatology and Venereology Pub Date : 2021-04-02 DOI: 10.3126/NJDVL.V19I1.35955

A. Bhatta, U. Keyal, Yeqiang Liu

引用次数: 0

Varicella in COVID-19: A Case Report 2019冠状病毒病水痘一例报告

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Egyptian Journal of Dermatology and Venereology Pub Date : 2021-04-02 DOI: 10.3126/NJDVL.V19I1.35957

S. Shrestha, A. Joshi

引用次数: 0

Effect of Subcision and Microneedling in the Treatment of Atrophic Acne Scars in Ten Patients: A Case Series 微针治疗萎缩性痤疮瘢痕10例疗效观察

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Egyptian Journal of Dermatology and Venereology Pub Date : 2021-04-02 DOI: 10.3126/NJDVL.V19I1.30974

Megha Tandon

{"title":"Effect of Subcision and Microneedling in the Treatment of Atrophic Acne Scars in Ten Patients: A Case Series","authors":"Megha Tandon","doi":"10.3126/NJDVL.V19I1.30974","DOIUrl":"https://doi.org/10.3126/NJDVL.V19I1.30974","url":null,"abstract":"Background: Acne vulgaris is a common condition with a prevalence of over 90% among adolescents and postacne scarring is a well known sequelae. Different types of scars (ice pick, boxcar, and rolling scars) warrant a customized approach of treatment for each type. We propose a novel treatment of atrophic acne scars using combination of subcision and microneedling. Materials and Methods: Ten consecutive patients of skin types III IV with moderate and severe facial acne scarring received three sequential subcision and micro-needling treatments after informed consent over a period of three months with an interval of 4 weeks between each session. Goodman and Baron’s qualitative and quantitative acne scar grading systems along with side by side comparison of pre-operative and post-operative photographs were used for assessment at the end of three sessions of the combination procedure. Results: Estimation of improvement with Goodman and Baron’s Global qualitative acne scarring system, we found good results in patients with Grades 3 and 4 acne scars. Out of 7 patients with grade 4 scars, 29% showed improvement by 2 grades and 71% showed improvement by 1 grade and all the 3 patients with grade 3 scars showed improvement by 1 grade. Quantitative assessment showed 30% patients had minimal improvement, 50% had moderate improvement and 20% had good improvement in scars. Adverse effects were transient pain, erythema and oedema. Conclusion: Subcision and microneedling are simple and inexpensive office procedures which in combination are well tolerated and are efficacious in treatment of moderate and severe acne scars.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"42 1","pages":"74-80"},"PeriodicalIF":0.4,"publicationDate":"2021-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87501827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Observational Study to Evaluate Quality of Life in Patients with Melasma in A Tertiary Level Hospital of Pokhara 博卡拉某三级医院黄褐斑患者生活质量评价的观察性研究

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Egyptian Journal of Dermatology and Venereology Pub Date : 2021-04-02 DOI: 10.3126/NJDVL.V19I1.35047

Prajwal Pudasaini, S. Neupane

{"title":"An Observational Study to Evaluate Quality of Life in Patients with Melasma in A Tertiary Level Hospital of Pokhara","authors":"Prajwal Pudasaini, S. Neupane","doi":"10.3126/NJDVL.V19I1.35047","DOIUrl":"https://doi.org/10.3126/NJDVL.V19I1.35047","url":null,"abstract":"Introduction: Melasma is an acquired hyper melanosis that becomes more pronounced after sun exposure. Centro facial which is the commonest pattern followed by Malar and Mandibular are three clinical patterns of Melasma. Genetic influences, exposure to UV radiation, pregnancy, hormonal therapies, contribute to the pathogenesis of melasma. Melasma may considerably have significant effect on quality of life of patients. Objectives: The present study was conducted to evaluate the effects of melasma in quality of life (QoL) in the form of DLQI (Dermatology Life Quality Index) and severity of melasma according to Melasma Area and Severity Index (MASI). Materials and Methods: This is a hospital based cross-sectional prospective study conducted in 193 Melasma patients in the Department of Dermatology, Venereology and Leprology, Gandaki Medical College and Teaching Hospital, Pokhara from November 2018 to November 2019. MASI score was calculated and the patients were provided with a Nepali version of DLQI to fill up. Results: This study included 193 patients. Mean age of patients with melasma was 29.4 ± 8.5 years with maximum reported age of 59 years. The Mean age of onset of disease was 26.5 years. The Mean age of onset of disease had little impact on DLQI. The mean DLQI score was 10.9 ± 5.9, thus indicating “very large effect on patient’s life”. The mean MASI score was 6.6 ± 5.2. It was found that there was no correlation between severity of disease and DLQI scores (p=0.317) Conclusion: Melasma commonly affected females during second and third decades of life. It had a very large effect on patient’s life as assessed by DLQI.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"1 1","pages":"37-41"},"PeriodicalIF":0.4,"publicationDate":"2021-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91388538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Clinico-mycological Study of Dermatophytosis and Their Antifungal Susceptibility, A Hospital Based Study 医院皮肤真菌病临床真菌学研究及其抗真菌敏感性研究

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Egyptian Journal of Dermatology and Venereology Pub Date : 2021-04-02 DOI: 10.3126/NJDVL.V19I1.34693

M. Pradhan, Vikash Paudel

{"title":"Clinico-mycological Study of Dermatophytosis and Their Antifungal Susceptibility, A Hospital Based Study","authors":"M. Pradhan, Vikash Paudel","doi":"10.3126/NJDVL.V19I1.34693","DOIUrl":"https://doi.org/10.3126/NJDVL.V19I1.34693","url":null,"abstract":"Introduction: Dermatophytosis refers to superficial fungal infections of keratinized tissues caused by keratinophilic dermatophytes. It is the most common of the superficial fungal infections. Nowadays, these fungal infections are at a rise and run a prolonged course despite of treatment due to resistance to conventional antifungal agents. There is a felt need to conduct an epidemiological studies to know the change in the pattern and causes of widespread resistance. Objectives: This study was aimed at identifying clinico-mycological patterns of dermatophytic infections in patients attending the dermatology outpatient department of a tertiary care hospital in Birgunj and the adjoining areas. Materials and Methods: The study included cases of clinically diagnosed dermatophytosis from the outpatient department of Dermatology of National Medical College, Birgunj. Clinical and epidemiological data were collected as per proforma and skin scraping, hair plucking, and nail clipping were done and materials were examined microscopically by KOH mount then cultured on Sabouraud dextrose agar and antifungal susceptibility were done by disk diffusion test. Results: There were 349 patients recruited in the study, with a male: female ratio of 1.6:1. The most commonly affected age group was 20–29 years (27.3%). Tinea corporis was the most common type observed (38.1%). Potassium hydroxide positivity was seen in 228 samples (65.3%) and culture positivity was found in 202 samples (57.9%). The most common species identified was Trichophyton rubrum (55%). The most sensitive drug was itraconazole, and more number of resistances was noted with fluconazole. Conclusion: Dermatophytic infection is ecumenical in distribution with increased frequency in tropical and subtropical countries with variable epidemiology. Inadequate and irregular use of antifungal drugs has led to the emergence of resistant strains, which cause poor treatment outcomes. Thus, it is essential to test for antifungal sensitivity to check for resistance to antifungals.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"108 1","pages":"30-36"},"PeriodicalIF":0.4,"publicationDate":"2021-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75305986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical efficiency of narrowband-ultraviolet B phototherapy and methotrexate therapy and their effects on serum tumor necrosis factor-alpha in patients with cutaneous lichen planus 窄带紫外线B光疗与甲氨蝶呤治疗对皮肤扁平苔藓患者血清肿瘤坏死因子- α的影响

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Egyptian Journal of Dermatology and Venereology Pub Date : 2021-03-12 DOI: 10.22541/AU.161556028.81077251/V1

M. El-Hamd, Hasan Mohamed Ibrahim, Abdallah Elaiw Mohammed, Eisa Mohammed

{"title":"Clinical efficiency of narrowband-ultraviolet B phototherapy and methotrexate therapy and their effects on serum tumor necrosis factor-alpha in patients with cutaneous lichen planus","authors":"M. El-Hamd, Hasan Mohamed Ibrahim, Abdallah Elaiw Mohammed, Eisa Mohammed","doi":"10.22541/AU.161556028.81077251/V1","DOIUrl":"https://doi.org/10.22541/AU.161556028.81077251/V1","url":null,"abstract":"Objective This study aimed to assess the clinical efficiency of narrowband–ultraviolet B (NB–UVB) phototherapy and methotrexate (MTX) therapy and their effects on serum tumor necrosis factor-alpha (TNF-α) in patients with cutaneous lichen planus (CLP). Patients and methods The present prospective cohort study was carried out on 60 patients with CLP. The included patients were indiscriminately classified into two treatment groups: group A (30 patients) received NB–UVB phototherapy for three months and group B (30 patients) received MTX therapy for 3 months. All the patients were assessed clinically and TNF-α before and after treatments. Results There were no statistically significant differences between the two groups of treatment with regard to clinical improvement after treatment (P=0.149). Regarding the levels of TNF-α, there was a statistically significant difference between the two treatment groups after treatment (P=0.024). There was a statistically significant reduction in TNF-α level after treatment in the MTX group. Conclusion This study concluded that NB–UVB phototherapy and MTX therapy were clinically effective in the treatment of patients with CLP. MTX therapy was more efficient in the reduction of TNF-α level than NB–UVB phototherapy in patients with CLP.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"43 1","pages":"164 - 170"},"PeriodicalIF":0.4,"publicationDate":"2021-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41435978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanisms Underlying Induced Pseudo-Scleroderma among Patients with Phenylketonuria Metabolic Disorder 苯丙酮尿代谢紊乱患者诱发假性硬皮病的机制

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Egyptian Journal of Dermatology and Venereology Pub Date : 2021-03-02 DOI: 10.12970/2310-998X.2021.09.01

K. Asare, Justice Afrifa, Y. Opoku

引用次数: 1

Interrelationship between head lice infestation and nutritional status of Thai preschool nursery children in a remote community near Thailand-Cambodia international border: an observation 在泰国-柬埔寨国际边界附近的一个偏远社区，泰国学龄前托儿所儿童头虱感染与营养状况之间的相互关系:一项观察

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Egyptian Journal of Dermatology and Venereology Pub Date : 2021-01-01 DOI: 10.4103/ejdv.ejdv_8_20

B. Joob, V. Wiwanitkit

引用次数: 0

Childhood bullous systemic lupus erythematosus: unusual prognosis 儿童大疱性系统性红斑狼疮:异常预后

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Egyptian Journal of Dermatology and Venereology Pub Date : 2021-01-01 DOI: 10.4103/ejdv.ejdv_2_20

K. Gharib

{"title":"Childhood bullous systemic lupus erythematosus: unusual prognosis","authors":"K. Gharib","doi":"10.4103/ejdv.ejdv_2_20","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_2_20","url":null,"abstract":"Background Bullous systemic lupus erythematosus (BSLE) has rarely been described in pediatric lupus population, and the real prevalence of childhood-onset BSLE has not been reported. BSLE is a rare manifestation of systemic lupus erythematosus and is very rare in children. BSLE affects women more often than men, reflecting the female preponderance in systemic lupus erythematosus. It most often manifests in the second through fourth decades of life, but it has also been reported in children and older adults. Patients and methods Herein, we describe a case of a 10-year-old female patient who presented with a 1-year history of recurrent itchy urticated skin eruption, which was followed 2 months later (after the first year) by a generalized blistering eruption with photosensitivity. Results Histopathologic examination revealed a subepidermal blister and papillary-tip neutrophil microabscesses. Immunofluorescence studies showed linear immunoglobulin G (IgG) and IgC deposition along the BMZ with weaker staining of IgA and IgM. Laboratory tests revealed positive ANA, dsDNA, anti-SM antibodies, elevated erythrocyte sedimentation rate, and proteinuria. Conclusion Although the course of BSLE is often remitting, but not in our case, treatment with dapsone is successful in most cases of BSLE.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"41 1","pages":"16 - 21"},"PeriodicalIF":0.4,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43643918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1