Egyptian Journal of Dermatology and Venereology最新文献_第5页

Frequency of skin diseases in Egyptian population during coronavirus disease 2019 pandemic: a hospital-based cross-sectional study 2019冠状病毒病大流行期间埃及人群皮肤病的频率：一项基于医院的横断面研究

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Egyptian Journal of Dermatology and Venereology Pub Date : 2022-09-01 DOI: 10.4103/ejdv.ejdv_38_21

M. Mohamed, N. Mohammed, R. Saleh

{"title":"Frequency of skin diseases in Egyptian population during coronavirus disease 2019 pandemic: a hospital-based cross-sectional study","authors":"M. Mohamed, N. Mohammed, R. Saleh","doi":"10.4103/ejdv.ejdv_38_21","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_38_21","url":null,"abstract":"Background Coronavirus disease 2019 (COVID-19) pandemic has resulted in remarkable changes in the profiles of diseases including dermatologic conditions. Aim To investigate the patterns of skin diseases in Egypt during the COVID-19 pandemic. Patients and methods In this cross-sectional study, we reviewed the data of patients who visited dermatology clinics between August 2020 and January 2021 and compared them with the data from the same clinics in the previous year. Results The total number of patients who attended the dermatology clinics between August 2020 and January 2021 was 803 as compared with 1611 patients in the corresponding period of the previous year (49.84% reduction). During the COVID-19 pandemic, there was a significant increase in the frequency of allergic contact dermatitis, irritant contact dermatitis, pityriasis rosea, alopecia areata, erythema multiforme, vasculitis, herpes zoster, and chicken pox (P<0.05). On the contrary, some dermatological conditions such as urticaria and nonscarring hair loss had significantly decreased frequencies during the COVID-19 pandemic (P<0.05). Several skin diseases had unchanged frequencies during the COVID-19 pandemic. These included skin infections (other than viral infections), bullous disorders, some eczematous skin diseases, papulosquamous disorders, and disorders of skin pigmentation. Conclusion This study indicates a significant reduction in the total number of patients attending dermatology clinics in Egypt during the COVID-19 pandemic. The frequency of some skin diseases increased significantly, whereas other skin diseases decreased significantly or remained unchanged during the pandemic. Periodic evaluation of the epidemiologic characteristics of skin diseases is required at different stages of evolution of the COVID-19 pandemic.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"42 1","pages":"167 - 173"},"PeriodicalIF":0.4,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49459436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum interleukin-33 level and psoriasis diagnosis 血清白细胞介素33水平与银屑病诊断

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Egyptian Journal of Dermatology and Venereology Pub Date : 2022-09-01 DOI: 10.4103/ejdv.ejdv_48_21

P. Sookaromdee, V. Wiwanitkit

引用次数: 0

Median canaliform nail dystrophy involving thumb nails and great toe nails: a rare entity 中位管状甲营养不良，包括拇指甲和大趾甲:罕见病例

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Egyptian Journal of Dermatology and Venereology Pub Date : 2022-09-01 DOI: 10.4103/ejdv.ejdv_30_21

Vikram Arragudla, A. Parthasaradhi

引用次数: 0

Optimizing acne care via teledermatology − where do we stand? 通过远程皮肤科优化痤疮护理——我们的立场是什么？

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Egyptian Journal of Dermatology and Venereology Pub Date : 2022-09-01 DOI: 10.4103/ejdv.ejdv_44_21

Rajat Kandhari

引用次数: 0

An insight into the value of circular RNA in psoriasis pathogenesis and its correlation with PASI score 环状RNA在银屑病发病机制中的价值及其与PASI评分的相关性

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Egyptian Journal of Dermatology and Venereology Pub Date : 2022-09-01 DOI: 10.4103/ejdv.ejdv_36_21

Rehab Naguib, A. El-Rifaie, Abd-ElA El-Taweel, M. Dahab

{"title":"An insight into the value of circular RNA in psoriasis pathogenesis and its correlation with PASI score","authors":"Rehab Naguib, A. El-Rifaie, Abd-ElA El-Taweel, M. Dahab","doi":"10.4103/ejdv.ejdv_36_21","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_36_21","url":null,"abstract":"Background Psoriasis is a chronic hyperproliferative inflammatory disease, in which genetic and environmental factors have an important role, but the exact cause is yet unknown. Circular RNAs (circRNAs) are regulatory noncoding RNAs. They play an important role in multiple physiological and pathological processes, such as cancer, cardiovascular diseases, and neuronal diseases. Some circRNAs are involved in regulating immunity, inflammation, and cell proliferation in many types of cells. Aim To detect the expression of circRNA (Circ0061012) in psoriatic skin of diseased patients as compared with normal control persons to investigate the possible role of circRNA in psoriasis pathogenesis and its correlation with disease severity. Patients and methods The present study included 30 psoriatic patients and 30 healthy controls. A 4-mm punch skin biopsy was taken from patients (psoriatic lesion) and controls, and it was kept in the lysis solution for the stability of the studied parameters and was kept frozen at ‑80°Celsius till analysis of circRNA by real-time polymerase chain reaction. Results The tissue level of circRNA (Circ0061012) was significantly higher among patients with psoriasis as compared with normal control individuals. Conclusion circRNA could contribute to psoriasis pathogenesis through its immunomodulatory role, so it might be a therapeutic target in the future.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"42 1","pages":"155 - 158"},"PeriodicalIF":0.4,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48838439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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Egyptian Journal of Dermatology and Venereology Pub Date : 2022-05-01 DOI: 10.4103/ejdv.ejdv_34_21

Rehab Naguib, Abd-ElAziz El-Rifaie, EmanA.Z. Eissa, L. Rashed

{"title":"Autophagy-related gene 16L1 value in chronic plaque psoriasis","authors":"Rehab Naguib, Abd-ElAziz El-Rifaie, EmanA.Z. Eissa, L. Rashed","doi":"10.4103/ejdv.ejdv_34_21","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_34_21","url":null,"abstract":"Background Psoriasis is a chronic hyperproliferative inflammatory disease, in which genetic and environmental factors have an important role, but the exact cause is yet unknown. Autophagy is a strictly regulated lysosomal degradation pathway that is crucial for maintaining intracellular homeostasis and normal development. Dysregulation of autophagy-related genes has been recognized to increase susceptibility to diseases, such as inflammation, cancer, and autoimmune disorders. Aim Our study aimed to detect the expression of the autophagy-related gene 16L1 (ATG 16L) in psoriasis patients compared with normal controls to investigate the role of autophagy in the pathogenesis of this disease. Patients and methods This case–control study included 30 psoriasis patients and 30 healthy controls. Punch skin biopsies of 4 mm were taken from psoriatic lesions and then from the controls and they were kept in a lysis solution for the stability of the studied parameters and were kept frozen at –80°C till analysis of ATG 16L using real-time PCR. Results The level of the ATG 16L1 in the lesional skin of psoriasis was significantly increased compared with normal controls (P<0.001). Limitation Limited number of patients were included in this study (30 patients). Conclusion Autophagy process may play an important role in the pathogenesis of psoriasis disease.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"42 1","pages":"137 - 140"},"PeriodicalIF":0.4,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48860153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence and risk factors associated with acanthosis nigricans in primary school children 小学生黑棘皮病患病率及相关危险因素

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Egyptian Journal of Dermatology and Venereology Pub Date : 2022-05-01 DOI: 10.4103/ejdv.ejdv_16_21

N. Mohamad, Samar El-Tahlawy, Naglaa A. El Sherbiny, Eman Ebrahim

{"title":"Prevalence and risk factors associated with acanthosis nigricans in primary school children","authors":"N. Mohamad, Samar El-Tahlawy, Naglaa A. El Sherbiny, Eman Ebrahim","doi":"10.4103/ejdv.ejdv_16_21","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_16_21","url":null,"abstract":"Background Acanthosis nigricans (AN) is characterized by pigmented velvety thickening of the intertriginous body areas and neck. Many studies linked it to metabolic syndrome. Aim To detect the prevalence of AN among primary school children and to identify the associated risk factors. Patients and methods We included 2060 primary school students who were selected from two rural and four urban schools. The data were collected by questionnaire sheets that were fulfilled from each student in which present and past history for any disease were taken. Results The prevalence of AN was 17.7% of all examined students, higher in females (18.6%) than males (16.3%), but it was not statistically significant. More than half of the students 55.0% were of normal weight, 23.3% were overweight, and 21.7% were obese. In the current study, 69.1% of obese children were having AN. Conclusions Regular dermatologic examination for early identification of AN is required. AN in the knuckles should be considered as a classic site and highly prevalent. It should be borne in mind that coordinated efforts of medical professional teams may be required aiming to correct the underlying disease to improve the skin symptoms. Strict follow-up of patients with AN for early detection and management of insulin resistance and metabolic syndrome.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"42 1","pages":"97 - 102"},"PeriodicalIF":0.4,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41372002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Assessment of serum fatty acid-binding protein 4 and adiponectin levels in psoriasis patients and their correlation with disease severity 银屑病患者血清脂肪酸结合蛋白4和脂联素水平的评估及其与疾病严重程度的相关性

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Egyptian Journal of Dermatology and Venereology Pub Date : 2022-05-01 DOI: 10.4103/ejdv.ejdv_40_21

Noha Z Tawfik, A. Gomaa, Ranya Hassan, Basma El-alfy, Sara Rageh, N. Ismail

{"title":"Assessment of serum fatty acid-binding protein 4 and adiponectin levels in psoriasis patients and their correlation with disease severity","authors":"Noha Z Tawfik, A. Gomaa, Ranya Hassan, Basma El-alfy, Sara Rageh, N. Ismail","doi":"10.4103/ejdv.ejdv_40_21","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_40_21","url":null,"abstract":"Background Psoriasis is a chronic multifactorial autoimmune disease that has significant impacts on the quality of life. Adiponectin exhibits important anti-inflammatory, antioxidants, and antidiabetic effects. The role of fatty acid-binding protein 4 (FABP4) in psoriasis may be linked to tumor necrosis factor-α, which is one of the main cytokines contributing to the etiopathogenesis of this disease. Aim To understand the role of serum levels of FABP4 and adiponectin in disease pathogenesis and their correlation to disease severity. Patients and methods A case–control study was conducted on two groups. The first group included 35 psoriatic patients; the second group included 35 healthy volunteers matched for age, sex, and weight. Serum FABP4 and adiponectin levels were evaluated. Results The mean level of adiponectin among the patients was 4.3±1.4 ng/dl. The mean level of FABP4 among controls was 2.1±1.5 ng/dl. The difference between both groups was statistically significant (P<0.05). Conclusion In this study, serum FABP4 level and adiponectin levels were decreased in patients with psoriasis with no relation to disease severity. So, they cannot be used as clinical biomarkers of inflammation and disease activity in psoriasis","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"42 1","pages":"110 - 114"},"PeriodicalIF":0.4,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48920247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An observational study of infant dermatoses at a tertiary care health center in Delhi region 德里地区三级保健中心婴儿皮肤病的观察性研究

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Egyptian Journal of Dermatology and Venereology Pub Date : 2022-05-01 DOI: 10.4103/ejdv.ejdv_21_21

A. Dhillon, A. Chopra

{"title":"An observational study of infant dermatoses at a tertiary care health center in Delhi region","authors":"A. Dhillon, A. Chopra","doi":"10.4103/ejdv.ejdv_21_21","DOIUrl":"https://doi.org/10.4103/ejdv.ejdv_21_21","url":null,"abstract":"Objectives To know the prevalence and clinical patterns of infant dermatosis at a tertiary care referral institute. Patients and methods The present observational cross-sectional study was carried out on 508 neonates and infants with physiological and pathological skin conditions from August 1, 2018 to February 1, 2020. A standard study proforma was used to obtain detailed systemic and dermatological findings. Data entry was done in MS Excel, and data analysis was carried out using Statistical Package for Social Sciences, version 22.0. Results The common dermatoses were bacterial infection [folliculitis (29.03%) and staphylococcal scalded skin syndrome (19.35%)], fungal infections [candidal intertrigo (41.67%) and pityriasis versicolor (37.50%)], developmental abnormalities [accessory tragi (21.43%), anencephaly (14.29%), and cleft lip (14.29%)], diaper area eruptions [diaper dermatitis (81.82%), atopic dermatitis (45.92%), hemangiomas: infantile congenital hemangioma (60.87%) and nevus simplex/stork bite (21.74%)], hyperpigmentation disorders [Café-au-lait (44.44%) and congenital melanocytic nevi (22.22%)], hypopigmentation disorder [pityriasis alba (42.31%)], iatrogenic/traumatic disorders [Stevens-Johnson syndrome (40%)], immunologic disorders [insect bite hypersensitivity (41.18%) and acute urticaria (29.41%)], and transient benign disorders [Mongolian spots (23.28%) and Lanugo (14.29%)]. Conclusion Physiological dermatoses are transient and self-resolving and need to be differentiated from the pathological ones for management and parents’ reassurance. The pathological dermatoses are caused most commonly by infections and infestation, which warrants a clean and hygienic living. Owing to wide variety, burden, and public health problem of cutaneous dermatoses in infants, the current data can be useful in creating awareness among the dermatologists, pediatricians, and the health care system.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":"42 1","pages":"115 - 126"},"PeriodicalIF":0.4,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44970698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Unusual Triggers for Erythema Multiforme 多形性红斑的不寻常诱因

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Egyptian Journal of Dermatology and Venereology Pub Date : 2022-05-01 DOI: 10.4103/ejdv.ejdv_20_21

Manal Alsabbagh

引用次数: 0