International Journal of Diabetes and Metabolism最新文献

{"title":"Hypoglycemic Agents and Changes in Oxidative Stress Indices, Electrolytes, and Cardiovascular Risk Factors in Type 2 Diabetes","authors":"A. Nsonwu-Anyanwu, M. C. Nsonwu, C. Usoro","doi":"10.1159/000500912","DOIUrl":"https://doi.org/10.1159/000500912","url":null,"abstract":"Background: Metabolic complications of type 2 diabetes (T2DM), including dyslipidemia, electrolyte imbalance, and oxidative stress, have been shown to be modulated by hypoglycemic agents. Objective: The lipid profile, electrolytes, and oxidative stress indices were evaluated in T2DM. Methods: Fifty T2DM patients on metformin (n = 23), insulin (n = 17), and insulin/metformin (n = 10) and 40 controls were studied. Fasting plasma glucose (FPG), glycated hemoglobin (HbA1c), total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), total antioxidant capacity (TAC), total plasma peroxide (TPP), and total calcium (Ca) values were determined colorimetrically, sodium (Na+) and potassium (K+) levels were determined by flame photometry, chloride (Cl–) and bicarbonate (HCO3–) levels were determined by titration, and low-density lipoprotein cholesterol (LDL-C) levels, the atherogenic index of plasma (AIP), and the oxidative stress index (OSI) were determined by calculation. Data were analyzed using t test, analysis of variance, and Pearson’s correlation at p < 0.05. Results: T2DM patients had higher lipid peroxidation (TPP and OSI), atherogenic lipids (higher LDL-C and AIP and lower HDL-C), and lower antioxidants compared to controls (p < 0.05). T2DM patients with poor glycemic control had higher lipid peroxidation (higher TPP) and atherogenic lipids (TG and AIP) compared to those with good control (p < 0.05). Patients with T2DM for >5 years had higher protein glycosylation (higher HBA1c) and TC compared to those with T2DM for <5 years (p < 0.05). The class of hypoglycemic agent has no effect on the levels of all of the biochemical indices studied (p > 0.05). HDL-C correlated negatively with TG (r = –0.347, p = 0.013), LDL-C (r = –0.322, p = 0.018), and AIP (r = –0.714, p = 0.000) in T2DM. Conclusion: Chronic T2DM and poor glycemic control are associated with reduced antioxidants, lipid peroxidation, and atherogenic dyslipidemia. Different hypoglycemic agents exert no differential effects on the metabolic indices of T2DM studied.","PeriodicalId":405374,"journal":{"name":"International Journal of Diabetes and Metabolism","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129886783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Microvascular Complications in Type 2 Diabetics Attending a Primary Healthcare Centre in Sudan","authors":"M. Hussein, Sami Menasri","doi":"10.1159/000500914","DOIUrl":"https://doi.org/10.1159/000500914","url":null,"abstract":"Background: Diabetes mellitus (DM) has become a global public health challenge. The increasing urbanisation and the significant lifestyle changes have resulted in an unprecedented rise in the rates of type 2 DM and, consequently, its microvascular complications which are the major outcome of the disease. It is the low- and middle-income countries where 80% of the diabetic patients live that face the greatest burden of the disease. Study Objectives: Our primary objective was to estimate the frequency of microvascular complications among patients diagnosed with type 2 DM. Our secondary objective was to investigate the relationship between the microvascular outcomes and the different characteristics and potential variables among patients with type 2 DM. Methodology: An observational descriptive clinic-based cross-sectional survey was conducted to calculate the prevalence of microvascular complications of type 2 DM and the associated risk factors in a lower middle-income country, Sudan. The study was carried out at Shambat Primary Healthcare Clinic during the period between May and June 2018. All patients aged 20 years and above visiting the clinic were included. Patients excluded from selection were those on steroid therapy and those having bilateral eye cataract. A total of 209 patients constituted the sample and were selected through systemic random sampling. Statistical analysis was carried out using SPSS software version 21. For the continuous variables, the mean was used as a measure of central tendency and the standard deviation as a measure of dispersion. The associations between the microvascular complications and the other variables were analysed using the χ2 test. The p value was used as a test for statistical significance. Results: The response rate to the survey was 72.6%. The age of the enrolled subjects ranged from 24 to 88 years. Males constituted 61.7% of the study sample and females 38.3%. The mean body mass index (BMI) was 26.92 ± 2.06. Out of 209 patients known to have type 2 DM, 96 (45.9%) developed any of the microvascular complications. Nephropathy was the most frequent with a prevalence of 38.8%, followed by retinopathy and neuropathy with a frequency of 23.9 and 22.5%, respectively. The presence of other co-morbidities, namely hypertension, ischaemic heart disease, chronic kidney disease and dyslipidaemia, was a predictor for the occurrence of the small-vessel conditions. Conclusions: This study is probably the first of its kind to shed light on the magnitude of the microvascular complications of DM in Sudan. The yielded results reveal a significant burden caused by microvascular complications in the country. The concurrent presence of other chronic medical disorders, namely hypertension, ischaemic heart disease, chronic kidney disease and dyslipidaemia, amplifies the risk for the development of microvascular sequelae. The mean BMI of the sample reflects an overweight trend. Facing the high tide of the metabolic syndrome and ","PeriodicalId":405374,"journal":{"name":"International Journal of Diabetes and Metabolism","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123152272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediabetes Risk Assessment among Nurses Recruited in a Dubai Local Government Hospital: A Cross-Sectional Study","authors":"K. Abdullah, Susan C Jacob, H. Hussain, N. Salim","doi":"10.1159/000500913","DOIUrl":"https://doi.org/10.1159/000500913","url":null,"abstract":"Background: Nurses constitute half of the health workforce; their health could be at risk for chronic diseases, such as prediabetes and diabetes, as well as other occupational hazards, such as nurses’ stress. Health promotion, possibly workplace based, presents opportunities to safeguard the health of nurses. Using a prediabetes risk assessment tool for screening the nurses is important to ensure that they remain physically and mentally fit to perform their work and to comply with various health and safety regulations. Objective: The aims of this study were to determine the prevalence of prediabetes and its risk among nurses in Dubai Hospital and to study risk factors associated with prediabetes status. Methodology: A cross-sectional study was carried out in Dubai Hospital-Dubai Health Authority. A convenience sample was selected including 674 nurses estimated using OpenEpi software. Data was collected using a standardized diabetes risk assessment tool (The Finnish Diabetes Risk Score [FINDRISC]). Inclusion criteria were staff nurses working in Dubai Hospital in the age group from 25 to 64 years and nondiabetic staff in Dubai Hospital; an operational definition of prediabetes was used. The data were coded, and data entry and data analysis were made using SPSS 20 software version. The data were tested at a level of significance of 95%. Results: The study revealed that 42.7% of the participants had a low prediabetes risk, 38.4% had a slightly elevated prediabetes risk, 10.8% had a moderate prediabetes risk, 7.6% had a high prediabetes risk, and 0.5% had a very high prediabetes risk. Age, body mass index, waist circumference, history of antihypertensive drug treatment, history of high blood glucose, family history of diabetes, daily consumption of fruits, berries, or vegetables, and daily physical activity had a significant relationship with the prediabetes test (p < 0.01). Conclusions: Frequent testing is recommended to follow the risk score. Since we cannot control unmodifiable factors, such as age and family history, we can control modifiable factors, such as having a healthy lifestyle with healthy food and exercise to decrease the risk of developing type 2 diabetes. Health promotion and education can decrease the risk of developing type 2 diabetes.","PeriodicalId":405374,"journal":{"name":"International Journal of Diabetes and Metabolism","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126582380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Outcome of Diabetic Foot Ulcers in Basrah, Southern Iraq: A Cohort Study","authors":"Abdulhussein K. Marzoq, N. Shiaa, Raghda Zaboon, Qutaiba Baghlany, M. Alabbood","doi":"10.1159/000500911","DOIUrl":"https://doi.org/10.1159/000500911","url":null,"abstract":"Background: Diabetic foot ulcers are one of the most severe and costly complications of diabetes. Foot ulcers result from a combination of multiple causes including peripheral neuropathy and peripheral arterial disease. Patients with diabetic foot ulcers frequently require amputation of the lower limb. Objectives: The aim of this study was to assess the outcome of diabetic foot ulcers among Iraqi patients with diabetes and to examine the effect of some risk factors on healing of the ulcer. Methods: A cohort study was conducted on 100 patients from January to August 2017 at the Diabetic Foot Clinic, Alfayha Teaching Hospital, Basrah, Iraq. Results: A total of 100 patients with diabetic foot ulcers were included. The ulcers of 60% of the patients healed, whereas 8% persisted unhealed; 25% of the patients had a minor amputation, 5% had a major amputation, 1% had recurrent ulcers, and 1% died. The study showed statistically significant associations between diabetic foot ulcer healing and the following variables: patients’ age, glycated HbA1c, duration of diabetes, complications of diabetes like peripheral neuropathy, and ulcer size. Conclusions: Diabetic foot ulcer outcomes can be predicted by several factors, some of which are modifiable. Modification of the modifiable factors, such as better control of diabetes, treatment of peripheral neuropathy, and early management of ulcers, may improve the outcome and facilitate healing.","PeriodicalId":405374,"journal":{"name":"International Journal of Diabetes and Metabolism","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128786116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adherence of Patients with Diabetes to a Lifestyle Advice and Management Plan in Basra, Southern Iraq","authors":"Rawnaq A. Aladhab, M. Alabbood","doi":"10.1159/000500915","DOIUrl":"https://doi.org/10.1159/000500915","url":null,"abstract":"Background: Poor adherence to treatment regimens is a complex problem, especially for those with chronic illnesses. Noncompliance is believed to be the most common reason for treatment failure in diabetic patients, leading to the absence of metabolic control and accelerating disease-related complications. Data on the adherence of people with diabetes in Iraq are lacking. Objectives: The purpose of this study was to measure the rate of adherence among Iraqi patients with diabetes. Methods: This was a cross-sectional study conducted in the Specialized Endocrine and Diabetes Center in Basra, southern Iraq, during the period from June to August 2018. Data were collected by completing an interviewing questionnaire consisting of 13 questions. Results: A total of 231 patients were included in the study (54.5% were female). Mean age was 51.85 ± 13.55 years. 65.4% of the participants were taking their medications at the right times. The most common reason for not taking their medication (48.8%) was difficulty in remembering the dosage times. 40.7% of the participants were sedentary. Only one-third of the patients followed their doctors’ instructions regarding diet. Conclusions: The rate of adherence to medication regimens and lifestyle advice was unsatisfactory in this study group. The awareness of diabetic patients and their caring physicians about the importance of adherence to therapy, exercise, and diet should be emphasized.","PeriodicalId":405374,"journal":{"name":"International Journal of Diabetes and Metabolism","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132404150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Gestational Diabetes in South East Nigeria Using the Updated Diagnostic Guidelines","authors":"B. Onyenekwe, E. Young, C. B. Nwatu, C. Okafor, C. V. Ugwueze, Sunday N. Chukwu","doi":"10.1159/000500089","DOIUrl":"https://doi.org/10.1159/000500089","url":null,"abstract":"Background: Controversy still surrounds the choice of screening methods for gestational diabetes mellitus (GDM). Updated guidelines on hyperglycemias in pregnancy, recognizes 2 categories; Diabetes in pregnancy or pre-gestational diabetes and GDM. Early screening and diagnosis of GDM prevents maternal and fetal adverse outcomes. Study Objective: The aim of the study was to determine the prevalence of GDM and associated risk factors in a population of pregnant women in Enugu, South East Nigeria. Materials and Methods: The study was cross sectional and descriptive. All pregnant women attending the antenatal clinic were eligible for the study. A risk factor assessment questionnaire was administered. The one step universal screening with 75 g oral glucose tolerance test was used. The results were tabulated and categorized according to the World Health Organization (2013) Diagnostic Criteria. Statistical analysis was by SPSS version 21. Result: A total of 205 women were initially screened. Risk factors for GDM were identified in up to third of the subjects. They were aged 15–41 years (28.6 ± 4.9 years). OGTT was performed in 142 of the subjects (who came fasting). Gestational age was 8–40 weeks (28.5 ± 7.3); gravidity, 1–9 (2.4 ± 1.5); parity, 0–4 (1.3 ± 1.4); miscarriages, 0–5; and live births, 0–5. Blood glucose levels were 60–145 mg/dL (85.5 ± 12.5) fasting; 77–229 mg/dL (131.8 ± 27.2) at 1 h and 72–223 mg/dL (123.1 ± 25.0) at 2 h post glucose load. The WHO (2013) criteria for GDM were met in 51 subjects (35.9%), WHO 1999 in 29 (20.4%); IAPDSG/American Diabetes Association in 54 (38%); NICE in 44 (31%) and DIPSI in 25 (17.6%). Three subjects had diabetes in pregnancy. Previous miscarriages and macrosomic babies, family history of diabetes mellitus, previous GDM, hypertension and recurrent urinary tract infection were found to be significant risk factors for the development of GDM. Conclusion: The study highlights the high prevalence of GDM in our local population. At every level, screening and management of GDM should be incorporated as a routine antenatal service.","PeriodicalId":405374,"journal":{"name":"International Journal of Diabetes and Metabolism","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115147053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dyslipidaemia in Nigerian Children and Adolescents with Diabetes Mellitus: Prevalence and Associated Risk Factors","authors":"T. Jaja, I. Yarhere","doi":"10.1159/000499713","DOIUrl":"https://doi.org/10.1159/000499713","url":null,"abstract":"Background: Dyslipidaemia is prevalent in children and adolescents with type 1 diabetes and can worsen the presentation of chronic complications such as nephropathy, retinopathy, and neuropathy. The aim of this study is to determine the frequency of dyslipidaemia in children living with diabetes followed up at a paediatric endocrine clinic in southern Nigeria and to identify associations with demographic and clinical characteristics. Methods: The study is a cross-sectional, descriptive study of 22 children with diabetes followed up in a tertiary health care facility in southern Nigeria. Demographic data were retrieved from case files, and fasting lipid profile and HbA1c levels were determined for all subjects. Lipid abnormalities were defined based on the Expert Panel on Integrated Guidelines for Cardiovascular Health Risk Reduction in Children and Adolescents. Results: Twenty-two subjects aged 7–18 years were studied (mean age: 14.94 ± 3.59 years). There were 12 (54.5%) females. Both genders were comparable regarding age (p = 0.95). Mean duration of diabetes was 3.37 ± 2.38 years. Prevalence of lipid abnormalities include: hypertriglyceridaemia (86.4%), hypercholesterolemia (22.7%), abnormal HDL-C (36.4%), high LDL-C (13.6%), and non-HDL-C (22.7%). Hypercholesterolaemia was significantly higher in females (p = 0.02), and prevalence of hypertriglyceridaemia was higher in subjects ≥12 years (p = 0.019). There was no statistically significant difference in mean levels of various lipids between males and females. Six (27.3%) subjects had more than one lipid abnormality. There was no statistically significant association of lipid abnormalities with age, sex, weight category, and HbA1c level. Conclusion: The commonest lipid abnormality was hypertriglyceridaemia. About a quarter of the subjects had more than 1 lipid abnormality. Programs should therefore be targeted at improved control of glycemia and lipid levels to delay and prevent chronic complications.","PeriodicalId":405374,"journal":{"name":"International Journal of Diabetes and Metabolism","volume":"144 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123475668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Precipitating Factors for Diabetic Ketoacidosis among Patients with Type 1 Diabetes Mellitus: The Effect of Socioeconomic Status","authors":"Ahmed Hakim Al-Obaidi, H. Alidrisi, A. Mansour","doi":"10.1159/000499839","DOIUrl":"https://doi.org/10.1159/000499839","url":null,"abstract":"Background: Diabetic ketoacidosis (DKA) is one of the life-threatening acute complications of diabetes mellitus that mainly occurs in type 1 diabetes mellitus (T1DM). This study aimed to determine the socioeconomic factors associated with DKA in patients with T1DM in Basrah. Methods: A cross-sectional study including patients with T1DM who were admitted due to DKA or any other complaint in any of the teaching hospitals in Basrah, from February to October 2017. Data collection from each patient or their parents using a questionnaire was designed to capture personal, social, and disease-related factors. Results: One hundred forty-seven patients were involved in this study. They were compared with different factors to assess correlations with the risk of DKA. Younger age, underweight, being without a job, low personal and/or mother educational level, travel, home glucose monitoring less than 7 times a week, uncontrolled HbA1c and insulin stoppage as a cause of DKA regardless of the reasons to stop were associated with an increased risk of DKA. On the other hand, own home, availability of a glucometer for checking glucose, basal-bolus insulin regimen, insulin supply, and education at a tertiary center, correct injection technique whoever injected the insulin and dietary adherence, all were associated with a decreased risk of DKA. Other factors like gender, marital status, smoking status, father educational level, residency, income, personal home area, the frequency of HbA1c checking, and family history of diabetes were not associated with a significant effect on the DKA risk. Conclusions: Multiple socioeconomic factors interact to play a vital role in the development of DKA among patients with T1DM in Basrah.","PeriodicalId":405374,"journal":{"name":"International Journal of Diabetes and Metabolism","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126822430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnitude and Determinants of Hypothyroidism among Dyslipidemic Patients in Bangladesh: A Hospital-Based Cross-Sectional Study","authors":"Rokshana Rabeya, S. Zaman, A. Chowdhury, Mohammad Hayatun Nabi, M. D. Hawlader","doi":"10.1159/000499379","DOIUrl":"https://doi.org/10.1159/000499379","url":null,"abstract":"Background: Dyslipidemia is one of the most commonly experienced metabolic disorders, and it is strongly related to atherosclerotic cardiovascular disease. Hypothyroidism is a clinical syndrome resulting from a deficiency of thyroid hormones. Several studies from developed countries provide evidence that the rate of hypothyroidism in dyslipidemic patients is higher, but there is a scarcity of data from Bangladesh. Objectives: The aim of this study was to evaluate the prevalence and determinants of hypothyroidism in the adult dyslipidemic Bangladeshi population. Method: We examined the thyroid function of outpatients who were advised for fasting lipid profile and who were found to be dyslipidemic at a tertiary care hospital in Savar, Bangladesh, by a cross-sectional study conducted from July 2016 to June 2017. A total of 200 outpatients aged 20–65 years were enrolled in this study. A standard questionnaire was used to take record of sociodemographic, socioeconomic, and behavioral features. Body mass index (BMI) and blood pressure were examined with standard procedures. Biochemical parameters, such as fasting lipid profile and thyroid function markers, thyroid-stimulating hormone (TSH) and free thyroxine (fT4), were determined using standard assay methods. A p value < 0.05 was considered to be statistically significant. Results: Among the participants, 56% were male and 44% were female. 11.5% of the dyslipidemic subjects had hypothyroidism, among which 9.5% had subclinical hypothyroidism and only 2% had overt hypothyroidism. We also found that serum mean ± SD levels of TSH were significantly higher in the obese group of patients (p = 0.02). There was a significantly positive association of BMI and diastolic blood pressure with serum levels of TSH (p < 0.01) and fT4 (p = 0.02), respectively. Conclusion: Dyslipidemic patients should have more regular checkups. The findings of this study might be helpful in setting up the clinical management of dyslipidemias with or without normal thyroid function.","PeriodicalId":405374,"journal":{"name":"International Journal of Diabetes and Metabolism","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129096800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical screening of diabetes mellitus and coronary heart disease","authors":"Michael Jacobson M.","doi":"10.1159/000497556","DOIUrl":"https://doi.org/10.1159/000497556","url":null,"abstract":"A non-invasive, clinical system for low-cost screening of diabetes mellitus (DM) and coronary heart disease (CHD) is introduced and tested on patients with known conditions. Specifically, the heart rate variability (HRV) signal is extracted from 30 minutes of electrocardiogram (ECG), during which the patient was requested to perform specific actions. The HRV signal is then used as a diagnostic indicator of the presence of DM and CHD.","PeriodicalId":405374,"journal":{"name":"International Journal of Diabetes and Metabolism","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123124982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}