1型糖尿病患者糖尿病酮症酸中毒的诱发因素:社会经济地位的影响

Ahmed Hakim Al-Obaidi, H. Alidrisi, A. Mansour
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引用次数: 10

摘要

背景:糖尿病酮症酸中毒(Diabetic ketoacidosis, DKA)是主要发生在1型糖尿病(T1DM)的危及生命的急性并发症之一。本研究旨在确定与巴士拉T1DM患者DKA相关的社会经济因素。方法:对2017年2月至10月在巴士拉任何一家教学医院因DKA或任何其他投诉入院的T1DM患者进行横断面研究。使用问卷从每位患者或其父母处收集数据,旨在捕捉个人、社会和疾病相关因素。结果:147例患者纳入本研究。他们与不同的因素进行比较,以评估与DKA风险的相关性。年龄较小、体重过轻、没有工作、个人和/或母亲受教育程度低、旅行、每周家庭血糖监测少于7次、HbA1c不受控制和胰岛素停药是导致DKA的原因,而不管停药的原因是什么,这些都与DKA风险增加有关。另一方面,拥有自己的家、是否有血糖仪检查血糖、基础注射胰岛素方案、胰岛素供应、在三级医疗中心接受教育、注射胰岛素的正确注射技术和饮食依从性,都与DKA风险降低有关。性别、婚姻状况、吸烟状况、父亲受教育程度、居住地、收入、个人居住区域、HbA1c检查频率、糖尿病家族史等其他因素对DKA风险无显著影响。结论:多种社会经济因素相互作用,在巴士拉T1DM患者DKA的发展中发挥重要作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Precipitating Factors for Diabetic Ketoacidosis among Patients with Type 1 Diabetes Mellitus: The Effect of Socioeconomic Status
Background: Diabetic ketoacidosis (DKA) is one of the life-threatening acute complications of diabetes mellitus that mainly occurs in type 1 diabetes mellitus (T1DM). This study aimed to determine the socioeconomic factors associated with DKA in patients with T1DM in Basrah. Methods: A cross-sectional study including patients with T1DM who were admitted due to DKA or any other complaint in any of the teaching hospitals in Basrah, from February to October 2017. Data collection from each patient or their parents using a questionnaire was designed to capture personal, social, and disease-related factors. Results: One hundred forty-seven patients were involved in this study. They were compared with different factors to assess correlations with the risk of DKA. Younger age, underweight, being without a job, low personal and/or mother educational level, travel, home glucose monitoring less than 7 times a week, uncontrolled HbA1c and insulin stoppage as a cause of DKA regardless of the reasons to stop were associated with an increased risk of DKA. On the other hand, own home, availability of a glucometer for checking glucose, basal-bolus insulin regimen, insulin supply, and education at a tertiary center, correct injection technique whoever injected the insulin and dietary adherence, all were associated with a decreased risk of DKA. Other factors like gender, marital status, smoking status, father educational level, residency, income, personal home area, the frequency of HbA1c checking, and family history of diabetes were not associated with a significant effect on the DKA risk. Conclusions: Multiple socioeconomic factors interact to play a vital role in the development of DKA among patients with T1DM in Basrah.
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