伊拉克南部巴士拉市糖尿病足溃疡预后评估:一项队列研究

Abdulhussein K. Marzoq, N. Shiaa, Raghda Zaboon, Qutaiba Baghlany, M. Alabbood
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引用次数: 24

摘要

背景:糖尿病足溃疡是糖尿病最严重和最昂贵的并发症之一。足部溃疡是由多种原因引起的,包括周围神经病变和周围动脉疾病。糖尿病足溃疡患者经常需要截肢。目的:本研究的目的是评估伊拉克糖尿病患者糖尿病足溃疡的结局,并检查一些危险因素对溃疡愈合的影响。方法:对2017年1 - 8月在伊拉克巴士拉Alfayha教学医院糖尿病足门诊就诊的100例患者进行队列研究。结果:共纳入100例糖尿病足溃疡患者。60%的患者溃疡愈合,而8%的患者持续未愈合;25%的患者有轻微截肢,5%的患者有严重截肢,1%的患者有溃疡复发,1%的患者死亡。该研究显示,糖尿病足溃疡愈合与以下变量有统计学意义相关:患者年龄、糖化HbA1c、糖尿病病程、糖尿病并发症(如周围神经病变)和溃疡大小。结论:糖尿病足溃疡的预后可由多个因素预测,其中一些因素是可以改变的。改变可改变的因素,如更好地控制糖尿病、治疗周围神经病变和早期处理溃疡,可能会改善结果并促进愈合。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessment of the Outcome of Diabetic Foot Ulcers in Basrah, Southern Iraq: A Cohort Study
Background: Diabetic foot ulcers are one of the most severe and costly complications of diabetes. Foot ulcers result from a combination of multiple causes including peripheral neuropathy and peripheral arterial disease. Patients with diabetic foot ulcers frequently require amputation of the lower limb. Objectives: The aim of this study was to assess the outcome of diabetic foot ulcers among Iraqi patients with diabetes and to examine the effect of some risk factors on healing of the ulcer. Methods: A cohort study was conducted on 100 patients from January to August 2017 at the Diabetic Foot Clinic, Alfayha Teaching Hospital, Basrah, Iraq. Results: A total of 100 patients with diabetic foot ulcers were included. The ulcers of 60% of the patients healed, whereas 8% persisted unhealed; 25% of the patients had a minor amputation, 5% had a major amputation, 1% had recurrent ulcers, and 1% died. The study showed statistically significant associations between diabetic foot ulcer healing and the following variables: patients’ age, glycated HbA1c, duration of diabetes, complications of diabetes like peripheral neuropathy, and ulcer size. Conclusions: Diabetic foot ulcer outcomes can be predicted by several factors, some of which are modifiable. Modification of the modifiable factors, such as better control of diabetes, treatment of peripheral neuropathy, and early management of ulcers, may improve the outcome and facilitate healing.
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