International Journal of Hepatobiliary and Pancreatic Diseases最新文献

{"title":"A unique presentation of peliosis hepatis: A case report and comprehensive review of the literature","authors":"Alex Teshon, Crystal Walker, David P Schammel, Christine Marie-Gilligan Schammel, A Michael Devane","doi":"10.5348/100103z04at2023cr","DOIUrl":"https://doi.org/10.5348/100103z04at2023cr","url":null,"abstract":"Introduction: Peliosis hepatis (PH) is a rare benign vascular condition characterized by dilatation of hepatic sinusoids with occasional involvement of other organs. While associated with chronic immunosuppression, anabolic steroid use, oral contraceptive (OCP) use, human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), and infection with Bartonella, most PH patients are asymptomatic and, thus, identified incidentally. Compromised liver function is sometimes evident through laboratory tests; however, mortality results from cyst rupture and hemorrhage spontaneously or during surgical procedures. Case Report: We report a case of PH identified in a 33-year-old Black female radiologically evaluated for abnormal liver function tests. Computed tomography (CT) revealed enhancement of >100 lesions throughout both liver lobes; a CT-guided biopsy revealed mild macrovesicular steatosis and marked sinusoidal dilation, consistent with peliosis hepatis. Conclusion: We also present a comprehensive literature review describing the associated conditions, pathology, diagnostic methods, and treatment options for PH patients.","PeriodicalId":40532,"journal":{"name":"International Journal of Hepatobiliary and Pancreatic Diseases","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135409849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multicenter retrospective cohort study: Using trends in liver function tests to predict spontaneous passage of common bile duct stones in choledocholithiasis","authors":"Bardia Bidarmaghz, Nestor Sabat, A. Sharma, Hugh McGregor, J. Wong","doi":"10.5348/100102z04bb2023cr","DOIUrl":"https://doi.org/10.5348/100102z04bb2023cr","url":null,"abstract":"\u0000 Aim: Endoscopic retrograde cholangiopancreatography (ERCP) is the modality of choice in patients who are diagnosed with choledocholithiasis, but it carries potentially life-threatening risks and is not readily available in rural hospitals. Due to the lack of access to this service, trend of liver function tests is often used to predict the spontaneous passage of common bile duct (CBD) stone to prevent performing a negative ERCP. The aim of this study is to investigate whether the trend of liver function tests can be used to predict passage of common bile duct stone in patients who have radiological evidence of choledocholithiasis.\u0000\u0000 Methods: The liver function tests (LFTs) of patients diagnosed with choledocholithiasis at two separate hospitals in New Zealand and Australia were collected at two points retrospectively. The change in LFT values between diagnosis and immediately prior to ERCP was analyzed.\u0000\u0000 Results: Total of 409 patients were selected with 108 (26%) and 301 (74%) patients from Australia and New Zealand, respectively. Demographic and LFT values were statistically different between the two centers, but the female sex was significantly predominant in both. Cumulative data showed that 37% of patients diagnosed with choledocholithiasis had no stone during the ERCP procedure. Increased age was statistically significant in patients with a persistent stone on ERCP. Importantly, there was no statistical difference between LFT values of patients with persistent gallstones shown on ERCP compared to those who have passed their gallstones spontaneously. Aspartate aminotransferase (AST) was significantly associated with a persistent gallstone (p = 0.041), but its clinical value is questionable.\u0000\u0000 Conclusion: Decreasing trend in LFTs and their individual components are poor predictors of persistent gallstones in patients diagnosed with choledocholithiasis. Two-thirds of these patients have persistent stones and ERCP remains an important diagnostic and therapeutic modality for patients at significant risk of disease complications.\u0000","PeriodicalId":40532,"journal":{"name":"International Journal of Hepatobiliary and Pancreatic Diseases","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42734901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multicenter retrospective cohort study: Using trends in liver function tests to predict spontaneous passage of common bile duct stones in choledocholithiasis","authors":"Bardia Bidarmaghz, Nestor Sabat, Aditya Sharma, Hugh McGregor, Jason Wong","doi":"10.5348/100102z04bb2023ra","DOIUrl":"https://doi.org/10.5348/100102z04bb2023ra","url":null,"abstract":"Aim: Endoscopic retrograde cholangiopancreatography (ERCP) is the modality of choice in patients who are diagnosed with choledocholithiasis, but it carries potentially life-threatening risks and is not readily available in rural hospitals. Due to the lack of access to this service, trend of liver function tests is often used to predict the spontaneous passage of common bile duct (CBD) stone to prevent performing a negative ERCP. The aim of this study is to investigate whether the trend of liver function tests can be used to predict passage of common bile duct stone in patients who have radiological evidence of choledocholithiasis. Methods: The liver function tests (LFTs) of patients diagnosed with choledocholithiasis at two separate hospitals in New Zealand and Australia were collected at two points retrospectively. The change in LFT values between diagnosis and immediately prior to ERCP was analyzed. Results: Total of 409 patients were selected with 108 (26%) and 301 (74%) patients from Australia and New Zealand, respectively. Demographic and LFT values were statistically different between the two centers, but the female sex was significantly predominant in both. Cumulative data showed that 37% of patients diagnosed with choledocholithiasis had no stone during the ERCP procedure. Increased age was statistically significant in patients with a persistent stone on ERCP. Importantly, there was no statistical difference between LFT values of patients with persistent gallstones shown on ERCP compared to those who have passed their gallstones spontaneously. Aspartate aminotransferase (AST) was significantly associated with a persistent gallstone (p = 0.041), but its clinical value is questionable. Conclusion: Decreasing trend in LFTs and their individual components are poor predictors of persistent gallstones in patients diagnosed with choledocholithiasis. Two-thirds of these patients have persistent stones and ERCP remains an important diagnostic and therapeutic modality for patients at significant risk of disease complications.","PeriodicalId":40532,"journal":{"name":"International Journal of Hepatobiliary and Pancreatic Diseases","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134952942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IgG4-related inflammatory pseudotumor of the liver presenting as an incidental solitary liver mass","authors":"Mohammed Omer Mirghani, Z. Zia, Mohammad Haytham Mawardi, Zuhoor Almansouri, Niaz Ahmad","doi":"10.5348/100101z04mm2023cr","DOIUrl":"https://doi.org/10.5348/100101z04mm2023cr","url":null,"abstract":"\u0000 Inflammatory pseudotumor is increasingly being recognized as a definitive pathological entity affecting many organ systems and often difficult to distinguish from malignancy. We report a case of a 48-year-old female who presented with right hypochondrial pain associated with nausea and vomiting and recent weight loss. An ultrasound scan demonstrated gallstones without evidence of cholecystitis and an incidental 1.5 cm mass in the left liver lobe. A computed tomography (CT) and a magnetic resonance imaging (MRI) scan described the mass suspicious of a malignant tumour. An ultrasound-guided biopsy confirmed a benign inflammatory mass with lymphoplasmacytic infiltration staining for IgG4 and no evidence of malignancy. The patient had an elevated serum IgG4 levels. The patient was kept under surveillance. She underwent a laparoscopic cholecystectomy and at 18 months following the initial presentation the patient remains asymptomatic with stable liver lesion on ultrasound scan.\u0000","PeriodicalId":40532,"journal":{"name":"International Journal of Hepatobiliary and Pancreatic Diseases","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49228342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bile duct injury in laparoscopic cholecystectomy with a posterior infundibular approach","authors":"J. Geers, J. Jaekers, H. Topal, André Collignon, B. Topal","doi":"10.5348/100100z04mc2022ra","DOIUrl":"https://doi.org/10.5348/100100z04mc2022ra","url":null,"abstract":"\u0000 Aims: Bile duct injury (BDI) in laparoscopic cholecystectomy (LC) has a significant impact on morbidity and mortality. Although the critical view of safety (CVS) concept is the most widely supported approach to prevent BDI, alternative approaches are used as well. The aim was to evaluate the incidence, severity, and management of bile duct injury in LC, using a posterior infundibular approach.\u0000\u0000 Methods: This retrospective, monocentric cohort study includes patients who underwent LC for gallstone disease. Data were collected in a prospectively maintained database. Patients with BDI were identified and were analyzed in-depth.\u0000\u0000 Results: Between 1999 and 2018, 8389 consecutive patients were included (M/F 3288/5101; mean age 55 (standard deviation; SD ± 17) years). Mean length of postoperative hospital stay was two days (SD ± 4). Fourteen patients died after LC and 21 patients were identified with BDI. Seventeen BDI (81%) patients were managed minimally invasive (14 endoscopic, 3 laparoscopic), and 4 patients via laparotomy (3 hepaticojejunostomy, 1 primary suture). Severe complications (Clavien-Dindo ≥3) after BDI repair were observed in 6 patients. There was no BDI-related mortality. Median follow-up time was 113 months (range 5–238).\u0000\u0000 Conclusion: A posterior infundibular approach in LC was associated with a low incidence of BDI and no BDI-related mortality.\u0000","PeriodicalId":40532,"journal":{"name":"International Journal of Hepatobiliary and Pancreatic Diseases","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2022-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43130842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extrahepatic metastasis of hepatocellular carcinoma: A Malaysian case series","authors":"Ming Rhee Chai, Padmaan Sankaran, Lee Ming Yap","doi":"10.5348/100099z04mc2022cs","DOIUrl":"https://doi.org/10.5348/100099z04mc2022cs","url":null,"abstract":"\u0000 Introduction: Hepatocellular carcinoma (HCC) is a primary malignancy which arises from hepatocytes. It is the sixth most commonly diagnosed cancer and the third leading cause of cancer death worldwide in 2020. It predominantly metastasizes via the hematogenous route. However, there are possibility of distant metastasis via the lymphatic and bone dissemination in a few of HCC cases.\u0000\u0000 Case Series: We report two atypical cases of HCC with distant metastasis to cervical lymph node and bone in Malaysia. The first case reported is a HCC case of extrahepatic metastasis to cervical lymph node and the second case is a HCC case of extrahepatic metastasis to right femur.\u0000\u0000 Conclusion: The patients with atypical site of distant metastasis from HCC have poor prognosis. Overall physical examination should be done to prevent overlook for all the patients with HCC.\u0000","PeriodicalId":40532,"journal":{"name":"International Journal of Hepatobiliary and Pancreatic Diseases","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2022-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42326240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermoid cyst of pancreas: A report of an unusual case","authors":"A. Kola, Sanjay Singh","doi":"10.5348/100079z04ss2018cr","DOIUrl":"https://doi.org/10.5348/100079z04ss2018cr","url":null,"abstract":"Introduction: Pancreatic dermoid cyst is a rare, benign germ cell tumour and part of differential diagnosis for cystic neoplasm of pancreas, where it shows a slight preference for the pancreatic head. Case Report: We report a case of dermoid cyst of pancreas in a 17-year-old female patient. Patient presented with epigastric pain, anorexia and lump in epigastric region. CECT showed a well marginated cystic lesion with tiny speck of calcification in wall and fatty component anteriorly in epigastric region in midline and towards right arising from anterior aspect of head of pancreas. The fat planes surrounding the lesion are normal. The CBD was seen lying on posterior aspect of the lesion. Conclusion: Pre-operative diagnosis is difficult and it is usually diagnosed intraoperatively or by histopathological examination of the specimen.","PeriodicalId":40532,"journal":{"name":"International Journal of Hepatobiliary and Pancreatic Diseases","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71031993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of outcome in patients receiving stereotactic body radiation therapy for borderline resectable and locally advanced pancreatic cancers","authors":"Akanksha Anup, M. Bhandare, V. Chaudhari, R. Krishnatry, S. Shrikhande, A. Ramaswamy, A. Baheti, M. Ramadwar, R. Engineer","doi":"10.5348/100098z04aa2022ra","DOIUrl":"https://doi.org/10.5348/100098z04aa2022ra","url":null,"abstract":"","PeriodicalId":40532,"journal":{"name":"International Journal of Hepatobiliary and Pancreatic Diseases","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71032490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pancreatic serous cystadenoma with a high 68Ga DOTATOC-uptake mimicking a pancreatic NET","authors":"Erling A Bringeland, E. Rønne, Å. Kjellmo, Thomas M Keil","doi":"10.5348/100097z04eb2022eb","DOIUrl":"https://doi.org/10.5348/100097z04eb2022eb","url":null,"abstract":"","PeriodicalId":40532,"journal":{"name":"International Journal of Hepatobiliary and Pancreatic Diseases","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71032314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepatic focal nodular hyperplasia in a five-year-old healthy boy: A case report and literature review","authors":"A. Alfayez, Helayel Almodhaiberi, H. Al Hussaini, Ibrahim Alhasan, Abdullah A Algarni, Tharaa Y. Takrouni","doi":"10.5348/100095z04aa2021cr","DOIUrl":"https://doi.org/10.5348/100095z04aa2021cr","url":null,"abstract":"Introduction: Focal nodular hyperplasia is unusually seen in a pediatric age group, with few reported cases in the literature. We report the case of a 5-year-old boy not known to have medical illnesses, who was found to have a liver mass, underwent right trisectionectomy. The purpose of this report is to familiarize the healthcare community with similar events, review the literature, and discuss recommendations for future similar cases.\u0000 Case Report: A case of focal nodular hyperplasia (FNH) in a 5-year-old healthy boy who was found to have a huge liver lesion on ultrasound imaging due to a vague abdominal pain and distension. The patient underwent surgical excision of the mass due to abdominal pain, distension, and atypical features of FNH in radiological examinations. Histopathological analysis revealed a focal nodular hyperplasia.\u0000 Conclusion: Focal nodular hyperplasia considered a benign lesion that has no malignant transformation. The presenting symptoms are variable, usually asymptomatic. Laboratory tests have of little significance. Imaging modalities mainly ultrasound scan initially then magnetic resonance imaging (MRI) are useful to obtain more accurate characteristic features of the lesion. Uncertain diagnostic lesion needs to be biopsied and examined under microscopy. Confirming the diagnosis will follow an acceptable conservative management approach. Surgical resection is the preferred method in uncertain, questionable, or atypical features observed in radiological imaging.","PeriodicalId":40532,"journal":{"name":"International Journal of Hepatobiliary and Pancreatic Diseases","volume":"1 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46283062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}