International Journal of Hepatobiliary and Pancreatic Diseases最新文献_第6页

A review of transplantation for tumors other than hepatocellular carcinoma 肝细胞癌以外肿瘤的移植研究综述

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International Journal of Hepatobiliary and Pancreatic Diseases Pub Date : 2012-08-31 DOI: 10.5348/IJHPD-2012-8-RA-6

R. Barroso, D. Cherqui

{"title":"A review of transplantation for tumors other than hepatocellular carcinoma","authors":"R. Barroso, D. Cherqui","doi":"10.5348/IJHPD-2012-8-RA-6","DOIUrl":"https://doi.org/10.5348/IJHPD-2012-8-RA-6","url":null,"abstract":"Introduction: Debates are ongoing in many centers for the indications of liver transplantation for non-hepatocellular carcinoma tumors due to a number of factors. Standardized protocols are lacking and clinical outcomes vary. Objective: A review was performed of the numerous published articles, with focus on the management and clinical outcome of tumors besides hepatocellular carcinoma (HCC) which were treated by liver transplantation, namely, cholangiocarcinoma, neuroendocrine tumors and hepatic epitheloid hemangioendothelioma in an attempt to promote a more standardized guideline. Discussion: Liver transplantation for cholangiocarcinoma reveals promising results in selected group of patients who underwent neoadjuvant chemoradiation prior to transplantation. For neuroendocrine tumors with liver metastases a number of selection criteria have been proposed in different centers, however the results of which are still variable. Transplantation is a viable option for unresectable hepatic epitheloid hemangioepithelioma with results at par with resection. Conclusion: Over time as patient selection, techniques, peri-operative care and the understanding of the different diseases improves, the results of liver transplantation for these tumors likewise will became favourable. However, standardization of the management and guidelines are still needed.","PeriodicalId":40532,"journal":{"name":"International Journal of Hepatobiliary and Pancreatic Diseases","volume":"2 1","pages":"24-30"},"PeriodicalIF":0.1,"publicationDate":"2012-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71032858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CT-Guided Fine-Needle Aspiration Cytology of Solid Pseudopapillary Tumor of the Pancreas: Case Series and Review of Literature ct引导下胰腺实性假乳头状瘤细针穿刺细胞学研究:病例系列及文献复习

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International Journal of Hepatobiliary and Pancreatic Diseases Pub Date : 2012-07-10 DOI: 10.5348/IJHPD-2012-7-CS-5

A. R. Choudhury, B. Mitra, P. Bhattacharya, A. Bhattacharya

引用次数: 3

Hepatic artery aneurysm rupture presenting as an upper GI bleed: A case report 肝动脉瘤破裂表现为上消化道出血1例

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International Journal of Hepatobiliary and Pancreatic Diseases Pub Date : 2012-06-02 DOI: 10.5348/IJHPD-2012-6-CR-4

M. Wayne, C. Wong, J. Kim, B. Gandolfi, D. Hudesman, R. Grossi

引用次数: 1

Solid pseudopapillary tumor of the pancreas: Report of five cases 胰腺实性假乳头状瘤:附5例报告

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International Journal of Hepatobiliary and Pancreatic Diseases Pub Date : 2012-03-20 DOI: 10.5348/IJHPD-2012-5-CS-3

Cameron D. Adkisson, Adam S. Harris, M. Bridges, J. Nguyen, H. Asbun, J. Stauffer

{"title":"Solid pseudopapillary tumor of the pancreas: Report of five cases","authors":"Cameron D. Adkisson, Adam S. Harris, M. Bridges, J. Nguyen, H. Asbun, J. Stauffer","doi":"10.5348/IJHPD-2012-5-CS-3","DOIUrl":"https://doi.org/10.5348/IJHPD-2012-5-CS-3","url":null,"abstract":"Introduction: Solid pseudopapillary tumor of the pancreas (SPT) is a rare pancreatic tumor with an unclear pathogenesis and good prognosis after resection. We report our experience with the diagnostic and therapeutic management of these tumors over 10 years. Case Series: A retrospective chart review was performed for all patients undergoing pancreatic resection at our institution from 2001-2011. Patients with final pathology demonstrating SPT were identified. Of 617 pancreatic resections performed at our institution, five patients (0.8%) were found to have solid pseudopapillary tumor of the pancreas. All patients were female with a mean age of 39.2 years. Abdominal pain was the presenting symptom in four patients. MRI demonstrated pancreatic head involvement in three patients and pancreatic tail involvement in one patient. CT scan was used to diagnose one tumor located in the body of the pancreas. Mean tumor size was 8.0 cm, Surgical treatment consisted of two open pancreaticoduodenectomies, one laparoscopic pancreaticoduodenectomy, one laparoscopic subtotal pancreatectomy and one laparoscopic distal pancreatectomy. Surgical pathology revealed no evidence of vascular invasion in any of the tumors and an Ro resection complete resection with no microscopic residual tumor was obtained in all patient. No patients had involved lymph nodes with a mean of 16 lymph nodes inspected. No complications from any pancreatic resection were observed. Conclusion: Solid pseudopapillary tumors of the pancreas are a rare but treatable pancreatic tumor. Complete surgical excision is the treatment of choice and can be achieved through an open or minimal access technique.","PeriodicalId":40532,"journal":{"name":"International Journal of Hepatobiliary and Pancreatic Diseases","volume":"2 1","pages":"9-14"},"PeriodicalIF":0.1,"publicationDate":"2012-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71032747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Is percutaneous cholecystostomy a safe alternative for neutropenic patients with severe biliary septic shock 经皮胆囊造瘘术是中性粒细胞减少患者合并严重胆道感染性休克的安全选择吗

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International Journal of Hepatobiliary and Pancreatic Diseases Pub Date : 2012-03-19 DOI: 10.5348/IJHPD-2012-3-CR-1

N. Simion

引用次数: 0

Liver pathology findings in infant with Caroli's syndrome 卡罗里氏综合征婴儿肝脏病理结果

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International Journal of Hepatobiliary and Pancreatic Diseases Pub Date : 2012-02-24 DOI: 10.5348/IJHPD-2011-4-CR-2

Blagica Dukova, B. Ilievski, S. Duganovska, Vladimir Chadikovski, A. Kostovski

{"title":"Liver pathology findings in infant with Caroli's syndrome","authors":"Blagica Dukova, B. Ilievski, S. Duganovska, Vladimir Chadikovski, A. Kostovski","doi":"10.5348/IJHPD-2011-4-CR-2","DOIUrl":"https://doi.org/10.5348/IJHPD-2011-4-CR-2","url":null,"abstract":"Introduction: Caroli’s syndrome (CS) is a rare congenital disorder characterized by intrahepatic bile duct dilatation and congenital hepatic fibrosis. The clinical features of this condition include signs of portal hypertension, cholangitis and lithiasis. Liver transplantation is the ultimate treatment in most patients with liver failure. Case Report: A three month old infant treated with the diagnosis of biliary atresia, after two liver biopsies presented with distended abdomen, hepatosplenomegaly and signs of portal hypertension. Liver transplantation was preformed after four months. We found ectatic hilar bile ducts and intrahepatic bile duct dilatation. The pathologic finding of congenital hepatic fibrosis and proliferated dilated bile ducts suggested the diagnosis of Caroli’s syndrome. Conclusion: Caroli’s disease and Caroli’s syndrome may represent single disorder distinguished by congenital hepatic fibrosis. Fibrosis itself leads to portal hypertension appearing late in patients with Caroli’s disease while it’s dynamic and progressive in CS. Elevated white blood cell count is due to recurrent cholangitis, cholestasis and hepatolithiasis. Caroli’s disease can be associated with extrahepatic bile duct dilatation, but the exact incidence is not known. CS often is associated with kidney lesions and cardiac disease. Liver transplantation should be preformed early. Symptoms are presented early in life due to congenital and progressive hepatic fibrosis. Caroli’s syndrome must be considered in differential diagnosis in neonates with jaundice, ascites and hepatosplenomegaly. The first child with liver transplantation in Republic of Macedonia was diagnosed as Caroli’s syndrome.","PeriodicalId":40532,"journal":{"name":"International Journal of Hepatobiliary and Pancreatic Diseases","volume":"2 1","pages":"4-8"},"PeriodicalIF":0.1,"publicationDate":"2012-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71032734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Avulsion of the common bile duct and ampulla of vater after blunt abdominal trauma: Case report and review of the literature 钝性腹部创伤后胆总管及壶腹撕裂:病例报告及文献复习

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International Journal of Hepatobiliary and Pancreatic Diseases Pub Date : 2011-01-01 DOI: 10.5348/IJHPD-2011-1-CR-1

A. Azzam

{"title":"Avulsion of the common bile duct and ampulla of vater after blunt abdominal trauma: Case report and review of the literature","authors":"A. Azzam","doi":"10.5348/IJHPD-2011-1-CR-1","DOIUrl":"https://doi.org/10.5348/IJHPD-2011-1-CR-1","url":null,"abstract":"Introduction: Extrahepatic bile ducts injuries from blunt abdominal trauma are very rare. The criticality and the difficulty of these injuries are increased by the duodenal wall and the main pancreatic duct injuries. These injuries therefore require special consideration. Diagnosis is always difficult and late and depends on suspicion. Proper management depends on the efficiency of the center, the surgeon and the severity of the injury. Case Report: A 28yearold male presented to the emergency unit complaining of falling from motor cycle. The patient was stable. Urgent ultrasound revealed mild intraperitoneal collection. Computerized tomography with contrast showed the same finding with left sided pleural effusion and fracture fifth rib. The patient’s condition began to deteriorate with time. Immediate exploration revealed complete avulsion of the CBD from the duodenum. Exteriorization of the CBD to outside the abdomen through the skin was done. The diagnosis of avulsion of the CBD from the sphincter of Oddi was a retrospective diagnosis. Conclusion: Simple maneuvers can be performed that will not harm the patient and may be of great benefit. In the present case, exteriorization of the CBD to outside by a simple urinary catheter gave us the chance to have an accurate postoperative diagnosis which was not available at the time of the operation. Drainage of the pancreatic and biliary secretions outside the abdomen with no added morbidities also gave us the chance and the time needed to treat other associated complications like respiratory problems.","PeriodicalId":40532,"journal":{"name":"International Journal of Hepatobiliary and Pancreatic Diseases","volume":"1 1","pages":"1"},"PeriodicalIF":0.1,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71032682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Clinical evaluation on the determination of plasma lysophosphatidic acid concentration in Chinese human pancreatic cancer 中国胰腺癌患者血浆溶血磷脂酸浓度测定的临床评价

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International Journal of Hepatobiliary and Pancreatic Diseases Pub Date : 2011-01-01 DOI: 10.54348/IJHPD-2011-2-OA-2

Gong Yongling, Wang Shaokai, C. Tao, Chen Jinfei, Wang Shukui, Cao Xiufeng, Lv Guangmei, Lim Pin

{"title":"Clinical evaluation on the determination of plasma lysophosphatidic acid concentration in Chinese human pancreatic cancer","authors":"Gong Yongling, Wang Shaokai, C. Tao, Chen Jinfei, Wang Shukui, Cao Xiufeng, Lv Guangmei, Lim Pin","doi":"10.54348/IJHPD-2011-2-OA-2","DOIUrl":"https://doi.org/10.54348/IJHPD-2011-2-OA-2","url":null,"abstract":"Aims: Observing the alteration of plasma Lysophosphatidic acid (LPA) concentration in patients with pancreatic cancer and evaluating its clinical potential for diagnosis. Methods: We examined the plasma LPA concentrations by using a LPA assay kit and related parameters of CA199, AFP and CEA were measured in 50 patients with pancreatic cancer, 32 patients with benign pancreatic lesions and 36 healthy check up volunteers. Findings were analyzed and correlation with pathological changes. Results: The LPA concentration was significantly higher in pancreatic cancer patients (4.10±2.03 µmol/L) than in patients with benign lesions (3.28±1.26µmol/L) and healthy controls (2.27±1.02 µmol/L) (p < 0.05). Plasma LPA concentration correlated with serum CA199 level (r = 0.9070) in patients with pancreatic cancer. For diagnosis of pancreatic cancer, the sensitivity of LPA was 89.6% and the specificity 79. 4%, while the sensitivity of CA199 was 91.8% and specificity 84.8%. Statistical analysis showed no difference between the plasma LPA concentration and serum CA199 activity. However, alteration of plasma LPA has shown significant correlations with the tumor size, pathological classification, pathological stage, infiltration of capsule cells, surrounding lymph nodes and specific histopathological features. Conclusion: LPA might provide clinical physicians with aditional indicator of diagnosis, metastasis and prognosis, making it a promising biomarker for pancreatic cancer. Our findings suggested that LPA would be a potential target for treatment of pancreatic cancers.","PeriodicalId":40532,"journal":{"name":"International Journal of Hepatobiliary and Pancreatic Diseases","volume":"1 1","pages":"6-12"},"PeriodicalIF":0.1,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70713699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0