Open Access Journal of Biogeneric Science and Research最新文献

{"title":"Dynamics of Covid-19 Cases in Russia","authors":"Mazurkin Pm","doi":"10.46718/jbgsr.2022.11.000265","DOIUrl":"https://doi.org/10.46718/jbgsr.2022.11.000265","url":null,"abstract":"A wavelet analysis was carried out using asymmetric wave functions of daily statistical data for all cases of Covid-19 dynamics in Russia from 03/01/2020 to 01/10/2022 for 681 days. The wavelet identification method showed that in Russia there is a very close oscillatory adaptation of the virus parameters. The main changes for 681 days occur in the first quantum of behavior in the form of a power function, which becomes the first component of the general formula according to Rene Descartes with asymmetric wavelets.","PeriodicalId":405266,"journal":{"name":"Open Access Journal of Biogeneric Science and Research","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122958270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the Major Gastrointestinal Parasites Community in Yili Horses in Zhaosu of Xinjiang, Western China","authors":"Shan-Hui Liu","doi":"10.46718/jbgsr.2022.11.000264","DOIUrl":"https://doi.org/10.46718/jbgsr.2022.11.000264","url":null,"abstract":"This investigation shows that is possible to determine fecundity and species composition of the gastrointestinal community in Yili horses and analyse the possible relationships with intestinal parasites using sex, age, and management strategy. A total of 118 of the 124 sampled horses were infested with oxyurids, ascaridids, Spiruridae, Anoplocephalidae, Gasterophilus, large strongyles (strongylids), and small strongyles (cyathostomins: cyathostomes). Adults and/or larvae from two strongylid and 11 cyathostomin species were identified, with the following proportions of oveall parasite abundance (as eggs per gram of faeces; EPG) in Yili horses: Strongylus equinus 82.26%, Strongylus edentatus 23.39%, Cyathostomum coronatum 34.68%, Cyathostomum subcoronatum 18.55%, Cylicostephanus longibursatus 56.45%, Cylicostephanus calicatus 75.81%, Cylicocyclus radiatum 3.23%, Cylicocyclus nassatus 72.58%, Cylicocyclus ultrajectinus 3.23%, Cylicocyclus elongatum 6.45%, Cylicodontophorus bicoronatum 8.87%, Cylicodontophorus euproctus 13.71%, Cylicodontophorus pateratum 23.39%. Significant differences in the prevalence of separate strongylid species or their proportions in the community were not observed between females and males or between age groups (p > 0.05). Young horses (< 3 years old) had more severe infections of P. equorum and Oxyuris equi. Free-ranging horses were more infected with S. equinus, O. equi, T. equi, and G. intestinalis than horses under other management strategies. The optimum treatment interval may vary depending on a range of factors, including the type of pasture, grazing practices, stocking density, time of the year, and climatic conditions. An EPG > 200 is the main deworming objective.","PeriodicalId":405266,"journal":{"name":"Open Access Journal of Biogeneric Science and Research","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115438668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevention and Control of Rabies in Animals and Humans in Ethiopia","authors":"Jemil Alemar Ali","doi":"10.46718/jbgsr.2022.11.000263","DOIUrl":"https://doi.org/10.46718/jbgsr.2022.11.000263","url":null,"abstract":"Summary Rabies, a viral disease caused bylyssa virus of family Rhabdoviridae. It is a fatal zoonotic disease with worldwide occurrence and endemic in developing countries of Africa and Asia. The disease generally affects all warm-blooded animals, even though it is primarily a disease of dogs in Ethiopia and elsewhere in Africa. More than 95% of human rabies cases are due to bites by infected animals, predominantly from saliva of domestic dogs. Once clinical symptoms appear, it is almost 100% fatal, in which the disease is one of the major public-health burdens in Ethiopia. The country has the second most rabies related deaths in Africa. Although it is entirely preventable, nearly 3000 lives are lost every year in Ethiopia, with high economic burden and Daily Adjusted Life-Years (DALYs). Mass dog vaccination along with prompt administration of post-exposure prophylaxis (PEP) to bite victims, public awareness and ‘One-Health’ approach are successful elements for rabies prevention and control programmes. Low effort of animal rabies control by government and stake holders, lack of finance, limited rabies diagnostic capacity, neglect and lack of coordination and among others are the challenges holding back not to control a century long deadly disease in resource limited African countries like Ethiopia. Thus, this paper provides a brief overview of the varied measures for Rabies prevention and control in animals and humans in Ethiopia. ELISA: Enzyme Linked Immunosorbent Assay; ERIG: Equine Rabies Immunoglobulin; FAT: Fluorescent Antibody Test; GARC: Global Alliance for Rabies Control; HRIG: Human Rabies Immunoglobulin; HDCV: Human Diploid Cell Vaccine; IU: International Unit; MEEREB: Middle East and Central Eastern Europe Rabies Expert Bureau; OIE: World Organization for Animal Health (Organization International des Epizootes); PEP: Post Exposure Prophylaxis; PrEP: Pre-Exposure Prophylaxis; PCECV: Purified Chick Embryo Cell Vaccine; PRP: Partners for Rabies Prevention; RABV: Rabies Virus; RIA: Rabies in Asia Foundation; RIG: Rabies Immunoglobulin; RMCV: Rhesus Monkey Kidney Cell Vaccine; RNA: Ribonucleic Acid; RT-PCR: Reverse Transcription Polymerase Chain Reaction; SEARG: Southern and Eastern Africa Rabies Group; UK: United Kingdom; USD: United States Dollar; UV: Ultra Violet; WHO: World Health Organization because the clinical findings are similar to those of furious and dumb rabies. In acute lead poisoning, the common clinical findings are blindness, convulsions, death within 2 and 4 days after onset, pharyngeal paralysis, dysphagia, weakness and recumbency. 7. Vitamin A deficiency in cattle- occurs in groups of young cattle from 6 months to 18 months of age not receiving adequate carotene intake or vitamin A supplementation and is characterized by blindness in the ocular form and episodes of tremors and convulsions.","PeriodicalId":405266,"journal":{"name":"Open Access Journal of Biogeneric Science and Research","volume":"907 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132603003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Debate about foster motherhood","authors":"Abbas Jedariforoughi","doi":"10.46718/jbgsr.2022.11.000262","DOIUrl":"https://doi.org/10.46718/jbgsr.2022.11.000262","url":null,"abstract":"","PeriodicalId":405266,"journal":{"name":"Open Access Journal of Biogeneric Science and Research","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126962041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Formulation Development of “RUNNY NOSE NAPKIN”","authors":"Smita N. More","doi":"10.46718/jbgsr.2022.11.000261","DOIUrl":"https://doi.org/10.46718/jbgsr.2022.11.000261","url":null,"abstract":"Purpose: To examine the efficiency of prepared formulation for cough and cold by comparing with marketed formulation which can be a supportive therapy in Hospitals in cost effective way. The Runny nose napkin is the quite traditional way but not formulated yet for the treatment of sneezing and coughing. Normally for the treatment of any runny nose we uses the antihistaminic agent, anti-tussive drugs, expectorants, but each formulation having its own limitations. We used the common route of inhalation for the drug targeting. Methods: Different concentration of all the ingredients used in formulation was studied for its effectiveness and stability study. The common ingredients including camphor, menthol, eucalyptus oil, cinnamon oil and many others are used in the fixed combination. Results: The ratio is fixed on the trial and error basis for achieving the required therapeutic value. Trials were done on few of the healthy volunteers who were having cough and cold were asked to inhale the napkin containing different combinations of ingredients to different patients. The most effective combination was optimized from the duration of treatment and stability of formulations. Conclusion: These cost effective and more hygienic napkins will be the better health care product.","PeriodicalId":405266,"journal":{"name":"Open Access Journal of Biogeneric Science and Research","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129199055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolomics Study of the Effects of Zinc Sulfate in Mild Hepatic Encephalopathy","authors":"Ying Li","doi":"10.46718/jbgsr.2022.11.000260","DOIUrl":"https://doi.org/10.46718/jbgsr.2022.11.000260","url":null,"abstract":"Background: Zinc may play a role in the metabolism of minimal hepatic encephalopathy (MHE). Objective: To investigate the metabolic changes in MHE rats treated by oral zinc sulfate administration. Methods: A total of 24 Sprague-Dawley rats were divided into three subgroups: MHE rats (n=8), ZN rats (MHE treated by zinc sulfate, n=8), and CN rats (sham operation controls, n=8). Morris water maze (MWM) was used to evaluate cognitive and motor functions. The metabolic changes of MHE, ZN, and CN rats were investigated using 1H nuclear magnetic resonance spectroscopy (1H-NMR) based metabolomics. Sparse projection to latent structures discriminant analysis was used to identify the key metabolites in MHE vs. ZN and MHE vs. CN. A diffusion algorithm was used for enrichment analysis of the key metabolomics in MHE. Results: Significant prolonged escape latency of MWM were seen in the MHE rats. Shorter escape latency is shown in ZN rats after zinc supplementation. The 1H-NMR spectroscopy of MHE, ZN and CN rats showed that 47 metabolites were identified for key metabolites analysis. The concentrations of GABA, lactate, alanine, aspartate, glutamate, and glutamine were significantly increased, while that of myo-inositol, taurine, leucine, and isoleucine were significantly decreased in MHE rats. The concentrations of myo-inositol, taurine, glycine, leucine, and isoleucine were significantly increased, while that of lactate, alanine and glutamine were significantly decreased in ZN rats. Conclusions: Zinc sulfate can effectively improve cognitive impairments in MHE rats. Zn played a center role in the nitrogen metabolism of MHE by interfering alanine, glutamate, BACCs metabolisms and TCA circle.","PeriodicalId":405266,"journal":{"name":"Open Access Journal of Biogeneric Science and Research","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116067225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of the Strategy Map in Managing a Strategic Medical Entity During the Covid 19 Pandemic","authors":"Joanna  Jasinska","doi":"10.46718/jbgsr.2022.11.000259","DOIUrl":"https://doi.org/10.46718/jbgsr.2022.11.000259","url":null,"abstract":"Healthcare facilities that want to effectively manage the existing resources, as well as better and more efficiently respond to changes in the environment, looking for new management methods. Especially in times of limited resources of medical staff during the fight against the COVID 19 pandemic. Taking into account the above factors, managing a medical entity will require managers to be interested in the strategy map. The strategy map was analyzed and its role in the strategic management of a medical entity was shown. National and foreign literature and legislation were used for the analysis.","PeriodicalId":405266,"journal":{"name":"Open Access Journal of Biogeneric Science and Research","volume":"141 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131556283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short Course Digoxin in Acute Heart Failure","authors":" Nouira Semir","doi":"10.46718/jbgsr.2022.11.000258","DOIUrl":"https://doi.org/10.46718/jbgsr.2022.11.000258","url":null,"abstract":"Background Despite many critical voices regarding its efficacy and safety, digoxin may still have a role in the management of heart failure. The objective of this study was to evaluate the efficacy and safety of a short course digoxin therapy started in the emergency department based on clinical outcome after 30 days post hospital discharge. Methods From Great Tunisian registry, acute decompensated heart failure (ADHF) patients from January 2016 to January 2018 were identified. Patients with incomplete data were excluded. Digoxin treated and non-treated patients were compared in a matched control study with respect to primary outcomes of all-cause mortality and HF readmission. Secondary outcomes included changes of cardiac output (CO) and left ventricular ejection fraction (LVEF) after 72 hours of hospital admission. 229 matched non-treated with a median age of 67.4±12.8. After 72 hours of ED admission, there was a larger increase of CO (17.8 % vs 14%; p=0.015) and LVEF (14.4% vs 3.5%; p=0.003) in digoxin group compared to control group. At 30-day post-hospital discharge 34 (10.2%) patients died and 72 (21.6%) patients were readmitted. Use of digoxin was associated with decreased risk of death and hospital readmission [odds ratio, 0.79 (95% CI, 0.71-0.89)]. In ADHF patients, treatment with digoxin was associated with a significant decrease risk of 30-day mortality and hospital readmission with an improvement of cardiac output and left ventricular ejection fraction.","PeriodicalId":405266,"journal":{"name":"Open Access Journal of Biogeneric Science and Research","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126612710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Noise Pollution is One of the Main Health Impacts in Big Cities Today","authors":"T. Patarkalashvili","doi":"10.46718/jbgsr.2022.11.000257","DOIUrl":"https://doi.org/10.46718/jbgsr.2022.11.000257","url":null,"abstract":"Noise pollution today is one of the biggest health risks in big cities along with air pollution. It must be admitted that noise pollution was overlooked by scientists and city authorities lately. Noise pollution has adverse effect on all living organisms. Scientists confirm that noise incentives central nervous system that stimulus to release some hormones which increases risk of hypertension. Hypertension is related with many other cardiovascular and cerebrovascular diseases like infarction and strokes. Nowadays this tendency is being changed at last and noise pollution is often considered not only as harmful as air pollution but sometimes even more. European and North American countries have taken a number of measures to reduce noise level in big cities. Examples of popular measures include replacement of older paved roads with smoother asphalt, better management of traffic flows and reducing speed limits to 30 km. per hour, using less-noisy models of transport, like electric vehicles, cycling and walking.","PeriodicalId":405266,"journal":{"name":"Open Access Journal of Biogeneric Science and Research","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131300572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Qishan Formula Granules on Interventing Obesity Intestinal Microflora and Immune-Inflammatory","authors":"Wei Yan","doi":"10.46718/jbgsr.2022.11.000256","DOIUrl":"https://doi.org/10.46718/jbgsr.2022.11.000256","url":null,"abstract":"","PeriodicalId":405266,"journal":{"name":"Open Access Journal of Biogeneric Science and Research","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122779860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}