{"title":"Analysis of the Effectiveness of Conservative Treatment of Patients with Low-Back Pain by Regenerative Injecting Therapy","authors":"Telepenko Hv","doi":"10.46718/jbgsr.2020.03.000067","DOIUrl":"https://doi.org/10.46718/jbgsr.2020.03.000067","url":null,"abstract":"Background: An open-label clinical study was conducted to evaluate the efficacy and tolerability of regenerative injecting therapy. The purpose of the study: to assess the effectiveness of regenerative injecting therapy, as well as to analyze the degree of effectiveness of this method in patients with vertebrogenic pain syndromes. Materials and Methods: The study involved 30 patients of both sexes aged 20 to 60 years with vertebrogenic pain syndromes: chronic lumbalgia, vertebrogenic syndrome due to spondyloarthrosis, radiculopathy. General clinical (clinical and neurological, using scales for pain assessment), instrumental (X-ray, magnetic resonance imaging, ultrasound), laboratory methods were used. Results: The results of the study of regenerative injecting therapy showed a statistical improvement in the patients’ condition. According to the long-term results, conservative treatment (regenerative injecting therapy) has been shown to improve physical well-being, increase the ability to work, general perception of the quality of life of patients, and also had good tolerability. To evaluate the results of treatment of pain caused by protrusions and spondyloarthritis, using the method of application of platelet-enriched plasma.","PeriodicalId":405266,"journal":{"name":"Open Access Journal of Biogeneric Science and Research","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116436589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Air Quality Index with Particulate Matter (PM2.5) Improved after National Lockdown during COVID-19 Outbreak across Pakistan","authors":"Ahmed Khan Khurshied","doi":"10.46718/jbgsr.2020.03.000065","DOIUrl":"https://doi.org/10.46718/jbgsr.2020.03.000065","url":null,"abstract":"For Pakistan and as well as for world community COVID-19 is a huge tragedy. The defensive actions plan of Pakistan to contain COVID-19 pandemic includes self-isolation, home quarantine, social distancing and lockdown. The lockdown strategy adopted by the different provincial governments which involve non-functioning and closure of all the commerce business trade centers and industrial units. However, as a blessing in disguise, these measures have a positive effect on the environment in terms of reduction in toxic gasses like nitrogen dioxide, aerosols, particulate matter, and improvement in air quality. In this paper we analyzed the impact of lockdown on air quality index in major cities of Pakistan during different stages of government-enforced shutdowns in response to the COVID-19 outbreak. The data revealed that March to May lockdown 2020 lead to in a radical descent of approximately 35% to 50% in air pollution level in Karachi, Islamabad, Lahore, Peshawar, Quetta and many cities across the country. Pakistan’s Air Quality Index (AQI) levels improved with particulate matter (PM2.5) which reaches near about normal from unhealthy to moderate range considerably due to termination of economic activities, closed factories in hotspot zones and an additional reason for the uncertain variations in NO2 emissions was the rapid fall in inner-city traffic, which by some estimates declined as much as 65% across Pakistan. The lockdown chapter facilitated to clean the environment and shown relationship of air pollution levels strongly linked with higher commercial activities (Transportation, energy production and industrial activities) along with small scale interventions at city levels. Further it is suggested that in order to avoid pollution intensities bouncing back, Pakistan need to swing from the existing poorly fossil fuel hooked economy to clean energy based systems. We found the fact that how the environment is self-healing during the lockdown and this study will be beneficial to environmentalists and industry professionals to make the future strategy for improving the environment. Further it is too early and premature to connect on long-term climate change as a result of lockdown.","PeriodicalId":405266,"journal":{"name":"Open Access Journal of Biogeneric Science and Research","volume":"106 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116463364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tuberculosis of the Breast with Erythema Nodosum: A Case Report","authors":"R. Richmond","doi":"10.46718/jbgsr.2020.02.000050","DOIUrl":"https://doi.org/10.46718/jbgsr.2020.02.000050","url":null,"abstract":"","PeriodicalId":405266,"journal":{"name":"Open Access Journal of Biogeneric Science and Research","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122056725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Analysis of Correlation between Temperature and Infection in Covid-2019 Transmission","authors":"Ahmed Khan Khurshied","doi":"10.46718/jbgsr.2020.03.000066","DOIUrl":"https://doi.org/10.46718/jbgsr.2020.03.000066","url":null,"abstract":"The COVID-19 epidemic is causing an international health emergency attention and imposing financial damage to economies to lock down the countries in strict quarantine measures. Further the relationship between temperature and humidity with COVID-19 affected cities around the world justifies exceptional consideration. Geographical location 30-50 °N’ of equator having an average temperatures between 5-11 °C, and absolute humidity (4-7 g/m3 ) had higher capacity of transmission of respiratory viruses due to environmental factors in which pathogen and host meet. The strategies to fight coronavirus must pay consideration to the environmental factors such as weather and climate, humidity, temperature, and airflow on the transmission of human respiratory viruses to identify further scientific knowledge to fill the gaps. Further the outbreak has some positive and negative impact on earth’s environment, which includes reduced CO2 level, and better air quality, while matter of concern for authorities is how to dispose-off infected waste tissue and old face masks.","PeriodicalId":405266,"journal":{"name":"Open Access Journal of Biogeneric Science and Research","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121902870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of Crispr-Cas 9 in Food and Agriculture Science: A Narrative Review","authors":"Arefin Paroma","doi":"10.46718/jbgsr.2020.02.000041","DOIUrl":"https://doi.org/10.46718/jbgsr.2020.02.000041","url":null,"abstract":"Genetic diversity is the foundation for introducing plant development programs. Scientists and breeders used various methods, ranging from modern crossing to classical biotechnologies, to address the restricted incidence of natural mutations. Incomplete gene disruption or spontaneous injection of transgenes into plant genomes also occurs in earlier generations of knockout and gain-offunction technologies. Recent advances in genetic engineering has brought numerous benefits to the food and agriculture sector by improving the essential features of agricultural features. The CRISPR / Cas9 technology emerges from a bacterial immune system of type II and represents a new age of selective genome editing technology that can be spread to almost all species. In this paper, we have focused on advancements in the utilization of the CRISPR-Cas9 system in the food and agricultural industry, particularly in the development of resistant crops with improved quality and productivity.","PeriodicalId":405266,"journal":{"name":"Open Access Journal of Biogeneric Science and Research","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128325754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The treatment of a child with birth asphyxia induced brain atrophy, adrenal hemorrhage, and bilateral hyperoxaluric nephrocalcinosis: A challenging case and a unique experience","authors":"Aamir Jalal Al-Mosawi","doi":"10.46718/jbgsr.2020.02.000043","DOIUrl":"https://doi.org/10.46718/jbgsr.2020.02.000043","url":null,"abstract":"Background: Birth asphyxia induced brain atrophy is an irreversible ominous condition that is generally presented as a severe form of cerebral palsy with a high possibility of the development of a serious handicap. There is no medical treatment known to be effective in this condition. The aim of this paper is to describe the treatment of a patient with this ominous condition that was literally brought the child back to life. Patients and methods: A boy aged one year and nine months with birth asphyxia induced brain atrophy, bilateral hyperoxaluric nephrocalcinosis with early renal dysfunction and ultrasonographic evidence of adrenal hemorrhage. The boy was almost lifeless; he was not opening his eyes nor showing any spontaneous movement. He was not responding to moderately painful stimuli. He was only feeding with difficulties, breathing and his heart was beating. The boy was markedly hypotonic, but with rather brisk knee reflexes. Results: The boy’s brain atrophy and neurological condition was treated with a new a multi-factorial treatment courses which led in about two years to a great improvement. Treatment of nephrocalcinosis with essential oil terpene preparation and oral pyridoxine resulted in complete disappearance of nephrocalcinosis within three months, and didn’t return with continuation of therapies. Conclusion: The treatment of severe forms birth asphyxia induced brain atrophy is a highly challenging situation that demands highly motivated parents that are able to cope with multiple therapies over a prolonged period, for an obvious improvement to occur.","PeriodicalId":405266,"journal":{"name":"Open Access Journal of Biogeneric Science and Research","volume":"140 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122408023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mechanical Ventilation","authors":"U. Koca","doi":"10.46718/jbgsr.2020.02.000039","DOIUrl":"https://doi.org/10.46718/jbgsr.2020.02.000039","url":null,"abstract":"Exponential function defines the situation where the rate of change in a function is proportional to the size of the variable. For example; while expiratory flow is highest at the beginning during a passive expiration, the lung volume decreases as expiry progresses as it approaches functional residual capacity. Time Constant refers to the rate of change in the function. While short-time functions change quickly, long-time functions change slowly. Pressure gradient is required for a flow to occur and a displacement of volume in mechanical ventilation. The movement equation reflects the pressure change that occurs in the airway opening during breathing. According to equality, the lung is equally expanded in all directions (isotropic expansion). Airway resistance is influenced by current, breath volume and airway dimensions. Total respiratory system compliance is the sum of the compliance of the lung and rib cage.","PeriodicalId":405266,"journal":{"name":"Open Access Journal of Biogeneric Science and Research","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130616591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}