“流鼻巾”的配方研制

Smita N. More
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引用次数: 0

摘要

目的:通过与市售咳寒方的比较,探讨复方咳寒方的治疗效果,为医院提供经济有效的辅助治疗。流鼻涕纸巾是一种非常传统的方法,但还没有专门用于治疗打喷嚏和咳嗽。通常治疗流鼻涕,我们使用抗组胺药、止咳药、祛痰药,但每种制剂都有其局限性。我们采用常见的吸入途径进行药物靶向。方法:对配方中各成分在不同浓度下的药效及稳定性进行研究。常用的成分包括樟脑、薄荷醇、桉树油、肉桂油和许多其他成分在固定组合中使用。结果:该比例是在试错的基础上确定的,以达到所需的治疗价值。研究人员在一些患有咳嗽和感冒的健康志愿者身上进行了试验,他们被要求吸入含有不同成分组合的餐巾纸,用于不同的病人。从治疗时间和制剂稳定性两方面优选出最有效的组合。结论:这些性价比高、更卫生的餐巾纸将是较好的保健品。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Formulation Development of “RUNNY NOSE NAPKIN”
Purpose: To examine the efficiency of prepared formulation for cough and cold by comparing with marketed formulation which can be a supportive therapy in Hospitals in cost effective way. The Runny nose napkin is the quite traditional way but not formulated yet for the treatment of sneezing and coughing. Normally for the treatment of any runny nose we uses the antihistaminic agent, anti-tussive drugs, expectorants, but each formulation having its own limitations. We used the common route of inhalation for the drug targeting. Methods: Different concentration of all the ingredients used in formulation was studied for its effectiveness and stability study. The common ingredients including camphor, menthol, eucalyptus oil, cinnamon oil and many others are used in the fixed combination. Results: The ratio is fixed on the trial and error basis for achieving the required therapeutic value. Trials were done on few of the healthy volunteers who were having cough and cold were asked to inhale the napkin containing different combinations of ingredients to different patients. The most effective combination was optimized from the duration of treatment and stability of formulations. Conclusion: These cost effective and more hygienic napkins will be the better health care product.
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