{"title":"Towards the utilization of LLMs for misinformation modeling and detection","authors":"Xiu-Xiu Zhan , Chuang Liu , Jianzhang Zhang","doi":"10.1016/j.plrev.2025.02.003","DOIUrl":"10.1016/j.plrev.2025.02.003","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"53 ","pages":"Pages 22-23"},"PeriodicalIF":13.7,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143510833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From pre-stimulus activity to the contents of consciousness – A spatiotemporal view: Reply to comments on “Beyond task response-Pre-stimulus activity modulates contents of consciousness”","authors":"Georg Northoff , Federico Zilio , Jianfeng Zhang","doi":"10.1016/j.plrev.2025.02.006","DOIUrl":"10.1016/j.plrev.2025.02.006","url":null,"abstract":"<div><div>What are the exact neuronal mechanisms of pre-post-stimulus interaction and how can that account for the intrinsically subjective nature of the contents of consciousness? This is the key question lurking behind the various excellent and very thoughtful commentaries to our target article which we group along four main topics and questions. (i) What is the role of neural features like alpha power, phase dynamics, trial-to-trial variability and fractal scale-free dynamics in yielding pre-post-stimulus interaction and its conscious contents. (ii) What do we mean by ‘content’ of consciousness? This concerns its meaning, its characterization as internal or external, and its relation to the basic subjectivity of consciousness. (iii) How does our approach stand to other theories of consciousness like the Dendritic Integration Theory (DIT), GNWT and IIT? This concerns the convergence among the different theories that highlight distinct aspects. (iv) How can we detail the spatiotemporal shaping of the contents of consciousness including their intrinsically subjective nature through pre-post-stimulus interaction? This concerns the details of how the non-additive pre-post-stimulus interaction shapes the subjective nature of our experience of conscious contents, that is, how the neuronal activity connects to the phenomenal features of consciousness. Together, we conclude that the contents of consciousness are shaped primarily in a temporal-dynamic and spatial-topographic way through the non-additive pre-post-stimulus interaction. Such spatiotemporal shaping of the contents in our consciousness constitutes their intrinsically subjective nature which must be distinguished from their (more objective) modulation by cognitive, sensory, affective, and motor functions.</div></div>","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"53 ","pages":"Pages 76-90"},"PeriodicalIF":13.7,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143534867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Caleb Rowe , Nathan Santiago , Jeffrey Warner , Vassiliy Tsytsarev , Elena A. Rozhkova , Ogechukwu Ngwu-Hyacinth , Mark Bolding
{"title":"Human perception of ionizing radiation","authors":"Caleb Rowe , Nathan Santiago , Jeffrey Warner , Vassiliy Tsytsarev , Elena A. Rozhkova , Ogechukwu Ngwu-Hyacinth , Mark Bolding","doi":"10.1016/j.plrev.2025.02.002","DOIUrl":"10.1016/j.plrev.2025.02.002","url":null,"abstract":"<div><div>Here we address the question of whether humans can perceive ionizing radiation. We conducted a thorough review of the clinical and experimental literature related to ionizing radiation, with a focus on its acute effects. Specifically, we examined the three domains of X-ray perception found in animals (abdominal, olfactory, and retinal), which led us to instances of ionizing radiation-induced hearing and taste sensory phenomena in humans thus suggesting that humans can perceive X-rays across various sensory modalities via multiple mechanisms. We also analyzed literature to understand the mechanisms associated with reported symptoms, this led us to the concept of radiomodulation, an understudied modulatory effect of sub-ablative ionizing radiation doses on neurons. Based on this review of the literature we propose the hypothesis that a significant radiomodulation mechanism is the formation of reactive oxygen species from radiolysis which activates immune and sensory signal transduction mechanisms specifically related to the redox activity in TRP and K<sup>+</sup> channels. Additionally, we find evidence to support the previous claims of perception stemming from Cherenkov radiation and ozone production which are perceived using canonical sensory modalities. Finally, for we provide a concise summary of the applications of ionizing radiation in clinical imaging and therapy, as well as prospects for future developments of radiation technologies for biomedical and fundamental research.</div></div>","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"53 ","pages":"Pages 1-21"},"PeriodicalIF":13.7,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143471229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dark brain energy: Toward an integrative model of spontaneous slow oscillations","authors":"Zhu-Qing Gong , Xi-Nian Zuo","doi":"10.1016/j.plrev.2025.02.001","DOIUrl":"10.1016/j.plrev.2025.02.001","url":null,"abstract":"<div><div>Neural oscillations facilitate the functioning of the human brain in spatial and temporal dimensions at various frequencies. These oscillations feature a universal frequency architecture that is governed by brain anatomy, ensuring frequency specificity remains invariant across different measurement techniques. Initial magnetic resonance imaging (MRI) methodology constrained functional MRI (fMRI) investigations to a singular frequency range, thereby neglecting the frequency characteristics inherent in blood oxygen level-dependent oscillations. With advancements in MRI technology, it has become feasible to decode intricate brain activities via multi-band frequency analysis (MBFA). During the past decade, the utilization of MBFA in fMRI studies has surged, unveiling frequency-dependent characteristics of spontaneous slow oscillations (SSOs) believed to base dark energy in the brain. There remains a dearth of conclusive insights and hypotheses pertaining to the properties and functionalities of SSOs in distinct bands. We surveyed the SSO MBFA studies during the past 15 years to delineate the attributes of SSOs and enlighten their correlated functions. We further proposed a model to elucidate the hierarchical organization of multi-band SSOs by integrating their function, aimed at bridging theoretical gaps and guiding future MBFA research endeavors.</div></div>","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"52 ","pages":"Pages 278-297"},"PeriodicalIF":13.7,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Thoughts, loud and silent. Comment on “The sound of thought: Form matters – The prosody of inner speech” by Kreiner and Eviatar","authors":"Jutta L. Mueller","doi":"10.1016/j.plrev.2025.01.011","DOIUrl":"10.1016/j.plrev.2025.01.011","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"52 ","pages":"Pages 253-255"},"PeriodicalIF":13.7,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143057455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Speech: A skeleton for thought? Comment on “The sound of thought: Form matters – The prosody of inner speech” by Hamutal Kreiner, Zohar Eviatar","authors":"Anne-Lise Giraud","doi":"10.1016/j.plrev.2025.01.010","DOIUrl":"10.1016/j.plrev.2025.01.010","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"52 ","pages":"Pages 274-277"},"PeriodicalIF":13.7,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143063050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reasonings on multiple strategies in differential systems","authors":"Nisrine Outada","doi":"10.1016/j.plrev.2025.01.009","DOIUrl":"10.1016/j.plrev.2025.01.009","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"52 ","pages":"Pages 248-249"},"PeriodicalIF":13.7,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Thoughts and thinkers: On the complementarity between objects and processes","authors":"Chris Fields , Michael Levin","doi":"10.1016/j.plrev.2025.01.008","DOIUrl":"10.1016/j.plrev.2025.01.008","url":null,"abstract":"<div><div>We argue that “processes versus objects” is not a useful dichotomy. There is, instead, substantial theoretical utility in viewing “objects” and “processes” as complementary ways of describing persistence through time, and hence the possibility of observation and manipulation. This way of thinking highlights the role of memory as an essential resource for observation, and makes it clear that “memory” and “time” are also mutually inter-defined, complementary concepts. We formulate our approach in terms of the Free Energy Principle (FEP) of Friston and colleagues and the fundamental idea from quantum theory that physical interactions can be represented by linear operators. Following Levin (2024) <span><span>[30]</span></span>, we emphasize that memory is, first and foremost, an interpretative function, from which the idea of memory as a record, at some level of accuracy, of past events is derivative. We conclude that the distinction between objects and processes is always contrived, and always misleading, and that science would be better served by abandoning it entirely.</div></div>","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"52 ","pages":"Pages 256-273"},"PeriodicalIF":13.7,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143057451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"On evolution of non-binding commitments","authors":"Zhao Song, The Anh Han","doi":"10.1016/j.plrev.2025.01.006","DOIUrl":"10.1016/j.plrev.2025.01.006","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"52 ","pages":"Pages 245-247"},"PeriodicalIF":13.7,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142997897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}