Physics of Life Reviews最新文献

Constrained confabulation: Comment on “The paradox of the self-studying brain” by Battaglia, Servajean, and Friston 约束虚构：评Battaglia、Servajean和Friston的“自我学习大脑的悖论”

IF 13.7 1区生物学

Physics of Life Reviews Pub Date : 2025-04-21 DOI: 10.1016/j.plrev.2025.04.005

Thomas Parr , Sanjay G. Manohar

引用次数: 0

Extending the common currency of the mind beyond the brain: Comment on "Kinematic coding: Measuring information in naturalistic behaviour" by Becchio et al. 将思维的通用货币扩展到大脑之外：对Becchio等人的“动态编码：测量自然行为中的信息”的评论。

IF 13.7 1区生物学

Physics of Life Reviews Pub Date : 2025-04-21 DOI: 10.1016/j.plrev.2025.04.006

Andrea I. Luppi

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Leveraging large language models for complex systems analysis: Opportunities, challenges, and future directions: Comment on “LLMs and generative agent-based models for complex systems research” by Y. Lu et al. 利用大型语言模型进行复杂系统分析：机遇、挑战和未来方向：对Y. Lu等人的“复杂系统研究的法学硕士和基于生成代理的模型”的评论。

IF 13.7 1区生物学

Physics of Life Reviews Pub Date : 2025-04-21 DOI: 10.1016/j.plrev.2025.04.003

Yanan Wang , Xiaofang Duan , Xing Pan , Yini Geng

引用次数: 0

Physiological noise: a comprehensive review on informative randomness in neural systems 生理噪声：神经系统信息随机性的综合综述

IF 13.7 1区生物学

Physics of Life Reviews Pub Date : 2025-04-14 DOI: 10.1016/j.plrev.2025.04.001

Andrea Scarciglia , Claudio Bonanno , Gaetano Valenza

{"title":"Physiological noise: a comprehensive review on informative randomness in neural systems","authors":"Andrea Scarciglia , Claudio Bonanno , Gaetano Valenza","doi":"10.1016/j.plrev.2025.04.001","DOIUrl":"10.1016/j.plrev.2025.04.001","url":null,"abstract":"<div><div>Noise is often regarded as mere interference in the analysis of biomedical signals. Nonetheless, stochasticity plays a critical and informative role in the dynamics of complex systems, particularly in neurocardiovascular and neural systems. This review provides a comprehensive exploration on informative randomness in physiological contexts, tracing the evolution of noise research from its foundations on Brownian motion to its applications in neural systems, including the neuroautonomic regulation of cardiovascular dynamics. Key distinctions are made between output (measurement) noise and dynamic (intrinsic) noise, which directly influence the system behaviors at various levels. Several physiological noise identification techniques, such as stochastic differential equations, Bayesian methods, and Kalman filters, are evaluated in real-world scenarios. Special emphasis is placed on the role of physiological noise in multiscale neural systems, such as brain dynamics, neuronal communication, and heart-brain interactions, highlighting how it shapes complex functions. Furthermore, physiological noise is presented as a potential clinical biomarker, offering insights into the underlying structure and health of neural systems. Future research is encouraged to investigate multivariate noise estimation methods and their implications for understanding causality and systemic interactions in neurocardiovascular networks.</div></div>","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"53 ","pages":"Pages 281-293"},"PeriodicalIF":13.7,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143835183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Expanding the horizon of interaction modeling in complex systems comment on “Topological change of soil microbiota networks for forest resilience under global warming” by Huiying Gong et al. 拓展复杂系统相互作用建模的视野——评龚慧英等的“全球变暖下森林恢复力的土壤微生物群网络拓扑变化”

IF 13.7 1区生物学

Physics of Life Reviews Pub Date : 2025-03-25 DOI: 10.1016/j.plrev.2025.03.016

Xiaoya Fan, Zhong Wang

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Causal cognition in the wild: Is disentanglement really necessary? Comment on “disentangled representations for causal cognition” by F. Torresan & M. Baltieri 野外因果认知：解缠真的有必要吗？评论F. Torresan和M. Baltieri的“因果认知的解纠缠表征”

IF 13.7 1区生物学

Physics of Life Reviews Pub Date : 2025-03-24 DOI: 10.1016/j.plrev.2025.03.021

Anna Finke , Vicente Raja

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Unlocking the brain's code: The crucial role of post-translational modifications in neurodevelopment and neurological function 解开大脑的密码：翻译后修饰在神经发育和神经功能中的关键作用

IF 13.7 1区生物学

Physics of Life Reviews Pub Date : 2025-03-23 DOI: 10.1016/j.plrev.2025.03.011

Peng Ye , Wangzheqi Zhang , Yan Liao , Ting Hu , Chun-Lei Jiang

{"title":"Unlocking the brain's code: The crucial role of post-translational modifications in neurodevelopment and neurological function","authors":"Peng Ye , Wangzheqi Zhang , Yan Liao , Ting Hu , Chun-Lei Jiang","doi":"10.1016/j.plrev.2025.03.011","DOIUrl":"10.1016/j.plrev.2025.03.011","url":null,"abstract":"<div><div>Post-translational modifications (PTMs) represent a crucial regulatory mechanism in the brain, influencing various processes, including neurodevelopment and neurological function. This review discusses the effects of PTMs, such as phosphorylation, ubiquitination, acetylation, and glycosylation, on neurodevelopment and central nervous system functionality. Although neurodevelopmental processes linked to PTMs are complex, proteins frequently converge within shared pathways. These pathways encompass neurodevelopmental processes, signaling mechanisms, neuronal migration, and synaptic connection formation, where PTMs act as dynamic regulators, ensuring the precise execution of brain functions. A detailed investigation of the fundamental mechanisms governing these pathways will contribute to a deeper understanding of nervous system functions and facilitate the identification of potential therapeutic targets. A thorough examination of the PTM landscape holds significant potential, not only in advancing knowledge but also in developing treatments for various neurological disorders.</div></div>","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"53 ","pages":"Pages 187-214"},"PeriodicalIF":13.7,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143679140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A new approach to quantify information in real-life, complex neuroscience processes. Comment on “Kinematic coding: Measuring information in naturalistic behavior” by Becchio, Pullar, Scaliti and Panzeri 在现实生活中，复杂的神经科学过程中量化信息的新方法。评Becchio、Pullar、Scaliti和Panzeri的《运动编码：测量自然行为中的信息》

IF 13.7 1区生物学

Physics of Life Reviews Pub Date : 2025-03-21 DOI: 10.1016/j.plrev.2025.03.014

Ana Sanchez Jimenez , Enrique Fernández Serra , Rodrigo Quian Quiroga

引用次数: 0

Informational embodiment: Computational role of information structure in codes and robots 信息体现：信息结构在代码和机器人中的计算作用

IF 13.7 1区生物学

Physics of Life Reviews Pub Date : 2025-03-21 DOI: 10.1016/j.plrev.2025.03.018

Alexandre Pitti , Max Austin , Kohei Nakajima , Yasuo Kuniyoshi

{"title":"Informational embodiment: Computational role of information structure in codes and robots","authors":"Alexandre Pitti , Max Austin , Kohei Nakajima , Yasuo Kuniyoshi","doi":"10.1016/j.plrev.2025.03.018","DOIUrl":"10.1016/j.plrev.2025.03.018","url":null,"abstract":"<div><div>The body morphology plays an important role in the way information is perceived and processed by an agent. We address an information theory (IT) account on how the precision of sensors, the accuracy of motors, their placement, the body geometry, shape the information structure in robots and computational codes. As an original idea, we envision the robot's body as a physical communication channel through which information is conveyed, in and out, despite intrinsic noise and material limitations. Following this, entropy, a measure of information and uncertainty, can be used to maximize the efficiency of robot design and of algorithmic codes <em>per se</em>. This is known as the principle of Entropy Maximization (PEM) introduced in biology by Barlow in 1969. The Shannon's source coding theorem provides then a framework to compare different types of bodies in terms of sensorimotor information. In line with the PEM, we introduce a special class of efficient codes used in IT that reached the Shannon limits in terms of information capacity for error correction and robustness against noise, and parsimony. These efficient codes, which exploit insightfully quantization and randomness, permit to deal with uncertainty, redundancy and compacity. These features can be used for perception and control in intelligent systems. In various examples and closing discussions, we reflect on the broader implications of our framework that we called <em>Informational Embodiment</em> to motor theory and bio-inspired robotics, touching upon concepts like motor synergies, reservoir computing, and morphological computation. These insights can contribute to a deeper understanding of how information theory intersects with the embodiment of intelligence in both natural and artificial systems.</div></div>","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"53 ","pages":"Pages 262-276"},"PeriodicalIF":13.7,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143747944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A kinetic theory approach for modeling Alzheimer's disease: Insights and challenges 阿尔茨海默病建模的动力学理论方法：见解和挑战

IF 13.7 1区生物学

Physics of Life Reviews Pub Date : 2025-03-21 DOI: 10.1016/j.plrev.2025.03.019

Nouamane Bakhdil

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