发布求助
文献互助 智能选刊 最新文献

Physics of Life Reviews最新文献

筛选
英文 中文
High-order interaction modeling of tumor-microenvironment crosstalk for tumor growth 肿瘤生长中肿瘤-微环境串扰的高阶相互作用模型
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2025-05-16 DOI: 10.1016/j.plrev.2025.05.007
Jincan Che , Yu Wang , Li Feng , Claudia Gragnoli , Christopher Griffin , Rongling Wu
{"title":"High-order interaction modeling of tumor-microenvironment crosstalk for tumor growth","authors":"Jincan Che ,&nbsp;Yu Wang ,&nbsp;Li Feng ,&nbsp;Claudia Gragnoli ,&nbsp;Christopher Griffin ,&nbsp;Rongling Wu","doi":"10.1016/j.plrev.2025.05.007","DOIUrl":"10.1016/j.plrev.2025.05.007","url":null,"abstract":"<div><div>Signaling interactions between cancer cells and nonmalignant cells in the tumor microenvironment (TME) are believed to influence tumor progression and drug resistance. However, the genomic machineries mediating such an influence remain elusive, making it difficult to determine therapeutic targets on the tumor and its microenvironment. Here, we argue that a computational model, derived from the integration of evolutionary game theory and ecosystem theory through allometric scaling law, can chart the genomic atlas of high-order interaction networks involving tumor cells, TME, and tumor mass. We assess the application of this model to identify the causal influence of gene-induced tumor-TME crosstalk on tumor growth. The findings demonstrate that cooperation and competition between tumor cells and their infiltrating microenvironment promote or inhibit tumor growth in diverse ways. We identify specific genes that govern this promotion or inhibition, which can be used as genetic targets to alter tumor growth. This model opens up a new avenue to precisely infer the genomic underpinnings of tumor-TME interactions and their impact on tumor progression from any omics data.</div></div>","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"54 ","pages":"Pages 11-23"},"PeriodicalIF":13.7,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144116392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
To enhance or not to enhance: A debate about cognitive enhancement from a psychological and neuroscientific perspective 增强或不增强：从心理学和神经科学的角度对认知增强的争论
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2025-05-14 DOI: 10.1016/j.plrev.2025.05.002
Sandra Grinschgl , Manuel Ninaus , Guilherme Wood , Aljoscha C. Neubauer
{"title":"To enhance or not to enhance: A debate about cognitive enhancement from a psychological and neuroscientific perspective","authors":"Sandra Grinschgl ,&nbsp;Manuel Ninaus ,&nbsp;Guilherme Wood ,&nbsp;Aljoscha C. Neubauer","doi":"10.1016/j.plrev.2025.05.002","DOIUrl":"10.1016/j.plrev.2025.05.002","url":null,"abstract":"<div><div>The enhancement of humans’ core cognitive abilities–such as intelligence–is a frequently debated topic in scientific and public discourse. Different enhancement methods such as cognitive trainings, smart drugs, and brain stimulation techniques have been proposed and tested to enhance human’s cognition. In this narrative review, we summarize the main psychological and neuroscientific findings regarding those cognitive enhancement methods. We thereby distinguish passive (e.g., smart drugs) and active enhancement methods (e.g., working memory training)–which require different levels of agency. While for both forms of enhancement there is no (or only little) empirical evidence on their effectiveness to improve overall cognitive abilities, passive methods entail severe risks. Thus, we criticize promoting an overly optimistic view on especially passive enhancement. Furthermore, we highlight which individuals might be willing to enhance themselves, related motivational aspects of cognitive enhancement, and ethical considerations thereof. To raise awareness for the (in)effectiveness and risks of passive and active enhancement, we propose a category framework that distinguishes cognitive enhancement from clinical methods to treat disorders or diagnosed deficits and introduces important dimensions thereof. Finally, we present open questions for psychological and neuroscientific research which should become part of enhancement debates. Taken together, our narrative review provides a broad overview and critical assessment of enhancement-related topics such as effectiveness and risks of enhancement methods, motivational aspects to apply enhancement, and societal implications of cognitive enhancement.</div></div>","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"54 ","pages":"Pages 58-77"},"PeriodicalIF":13.7,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144170412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Testing hypotheses on the major/minor dichotomy: movement, consonance/dissonance, and (the lack of) cross-species evidence. Comment on “The Major-Minor Mode Dichotomy in Music Perception” by Giulio Carraturo, Victor Pando-Naude, Marco Costa, Peter Vuust, Leonardo Bonetti, Elvira Brattico 测试关于主要/次要二分法的假设：运动，和谐/不和谐，以及（缺乏）跨物种证据。评朱利奥·卡拉图罗、维克多·潘多-诺德、马尔科·科斯塔、彼得·武乌斯特、莱昂纳多·博内蒂、埃尔维拉·布拉提科的《音乐感知中的大调-小调二分法
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2025-05-09 DOI: 10.1016/j.plrev.2025.05.001
Nicola Di Stefano , Andrea Ravignani
{"title":"Testing hypotheses on the major/minor dichotomy: movement, consonance/dissonance, and (the lack of) cross-species evidence. Comment on “The Major-Minor Mode Dichotomy in Music Perception” by Giulio Carraturo, Victor Pando-Naude, Marco Costa, Peter Vuust, Leonardo Bonetti, Elvira Brattico","authors":"Nicola Di Stefano ,&nbsp;Andrea Ravignani","doi":"10.1016/j.plrev.2025.05.001","DOIUrl":"10.1016/j.plrev.2025.05.001","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"54 ","pages":"Pages 3-4"},"PeriodicalIF":13.7,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“ABMs are dead, long live G-ABMs!”, or a roadmap for opinion dynamics studies “反弹道导弹死了，g -反弹道导弹万岁！”，或者是民意动态研究的路线图
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2025-05-05 DOI: 10.1016/j.plrev.2025.04.012
Laura Hernández
{"title":"“ABMs are dead, long live G-ABMs!”, or a roadmap for opinion dynamics studies","authors":"Laura Hernández","doi":"10.1016/j.plrev.2025.04.012","DOIUrl":"10.1016/j.plrev.2025.04.012","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"53 ","pages":"Pages 314-315"},"PeriodicalIF":13.7,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143905874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Are kinematic encoding and kinematic readout reciprocal phenomena? - Comment on "Kinematic coding: Measuring information in naturalistic behavior" by Cristina Becchio, Kiri Pullar, Eugenio Scaliti, Stefano Panzeri 运动编码和运动读出是相互作用的现象吗？-对Cristina Becchio， Kiri Pullar, Eugenio Scaliti， Stefano Panzeri所著《运动学编码：测量自然行为中的信息》一文的评论
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2025-04-30 DOI: 10.1016/j.plrev.2025.04.011
Rocco Mennella , François Quesque
{"title":"Are kinematic encoding and kinematic readout reciprocal phenomena? - Comment on \"Kinematic coding: Measuring information in naturalistic behavior\" by Cristina Becchio, Kiri Pullar, Eugenio Scaliti, Stefano Panzeri","authors":"Rocco Mennella ,&nbsp;François Quesque","doi":"10.1016/j.plrev.2025.04.011","DOIUrl":"10.1016/j.plrev.2025.04.011","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"54 ","pages":"Pages 1-2"},"PeriodicalIF":13.7,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143924736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diverse mathematical approaches to Alzheimer's disease 阿尔茨海默病的多种数学方法
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2025-04-29 DOI: 10.1016/j.plrev.2025.04.008
Parimita Roy
{"title":"Diverse mathematical approaches to Alzheimer's disease","authors":"Parimita Roy","doi":"10.1016/j.plrev.2025.04.008","DOIUrl":"10.1016/j.plrev.2025.04.008","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"53 ","pages":"Pages 316-317"},"PeriodicalIF":13.7,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143922939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MUSIC SELF-PROJECTION IN A MINOR MODE Comment on “The Major-Minor Mode Dichotomy in Music Perception” by Giulio Carraturo, Victor Pando-Naude, Marco Costa, Peter Vuust, Leonardo Bonetti, Elvira Brattico 评朱利奥·卡拉图罗、维克多·潘多-诺德、马尔科·科斯塔、彼得·武乌斯特、莱昂纳多·博内蒂、埃尔维拉·布拉提科的《音乐感知中的大调-小调二分法
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2025-04-28 DOI: 10.1016/j.plrev.2025.04.010
Antoni Rodriguez-Fornells , Clement François
{"title":"MUSIC SELF-PROJECTION IN A MINOR MODE Comment on “The Major-Minor Mode Dichotomy in Music Perception” by Giulio Carraturo, Victor Pando-Naude, Marco Costa, Peter Vuust, Leonardo Bonetti, Elvira Brattico","authors":"Antoni Rodriguez-Fornells ,&nbsp;Clement François","doi":"10.1016/j.plrev.2025.04.010","DOIUrl":"10.1016/j.plrev.2025.04.010","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"53 ","pages":"Pages 312-313"},"PeriodicalIF":13.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143904273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paradox or illusion? A comment on “The paradox of the self-studying brain” by Battaglia, Servajean, and Friston 悖论还是幻觉？对Battaglia、Servajean和Friston合著的《自学大脑的悖论》的评论
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2025-04-24 DOI: 10.1016/j.plrev.2025.04.009
Chris Fields
{"title":"Paradox or illusion? A comment on “The paradox of the self-studying brain” by Battaglia, Servajean, and Friston","authors":"Chris Fields","doi":"10.1016/j.plrev.2025.04.009","DOIUrl":"10.1016/j.plrev.2025.04.009","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"53 ","pages":"Pages 310-311"},"PeriodicalIF":13.7,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143894353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Revolutionizing dynamic microbiome network analysis via idopNetworks: Comment on “Topological change of soil microbiota networks for forest resilience under global warming” by Gong et al. 通过idopNetworks革新动态微生物群网络分析：对Gong等人“全球变暖下森林恢复力的土壤微生物群网络拓扑变化”的评论
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2025-04-24 DOI: 10.1016/j.plrev.2025.04.002
Hongzhe Li
{"title":"Revolutionizing dynamic microbiome network analysis via idopNetworks: Comment on “Topological change of soil microbiota networks for forest resilience under global warming” by Gong et al.","authors":"Hongzhe Li","doi":"10.1016/j.plrev.2025.04.002","DOIUrl":"10.1016/j.plrev.2025.04.002","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"53 ","pages":"Pages 303-304"},"PeriodicalIF":13.7,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143882912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Opportunities and challenges of LLMs in urban science 城市科学法学硕士的机遇与挑战
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2025-04-24 DOI: 10.1016/j.plrev.2025.04.004
Sandro M. Reia, Dieter Pfoser, Henrique F. de Arruda
{"title":"Opportunities and challenges of LLMs in urban science","authors":"Sandro M. Reia,&nbsp;Dieter Pfoser,&nbsp;Henrique F. de Arruda","doi":"10.1016/j.plrev.2025.04.004","DOIUrl":"10.1016/j.plrev.2025.04.004","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"53 ","pages":"Pages 305-306"},"PeriodicalIF":13.7,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143888166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信