Physics of Life Reviews最新文献

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Preliminaries to artificial consciousness: A multidimensional heuristic approach 人工意识初探:多维启发式方法。
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2025-01-03 DOI: 10.1016/j.plrev.2025.01.002
K. Evers , M. Farisco , R. Chatila , B.D. Earp , I.T. Freire , F. Hamker , E. Nemeth , P.F.M.J. Verschure , M. Khamassi
{"title":"Preliminaries to artificial consciousness: A multidimensional heuristic approach","authors":"K. Evers ,&nbsp;M. Farisco ,&nbsp;R. Chatila ,&nbsp;B.D. Earp ,&nbsp;I.T. Freire ,&nbsp;F. Hamker ,&nbsp;E. Nemeth ,&nbsp;P.F.M.J. Verschure ,&nbsp;M. Khamassi","doi":"10.1016/j.plrev.2025.01.002","DOIUrl":"10.1016/j.plrev.2025.01.002","url":null,"abstract":"<div><div>The pursuit of artificial consciousness requires conceptual clarity to navigate its theoretical and empirical challenges. This paper introduces a composite, multilevel, and multidimensional model of consciousness as a heuristic framework to guide research in this field. Consciousness is treated as a complex phenomenon, with distinct constituents and dimensions that can be operationalized for study and for evaluating their replication. We argue that this model provides a balanced approach to artificial consciousness research by avoiding binary thinking (e.g., conscious vs. non-conscious) and offering a structured basis for testable hypotheses. To illustrate its utility, we focus on \"awareness\" as a case study, demonstrating how specific dimensions of consciousness can be pragmatically analyzed and targeted for potential artificial instantiation. By breaking down the conceptual intricacies of consciousness and aligning them with practical research goals, this paper lays the groundwork for a robust strategy to advance the scientific and technical understanding of artificial consciousness.</div></div>","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"52 ","pages":"Pages 180-193"},"PeriodicalIF":13.7,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancing epidemic modeling: The role of LLMs and generative agent-based models Comment on LLMs and generative agent-based models for complex systems research by Lu et al. 对Lu等人在复杂系统研究中的llm和基于生成代理的模型的评论。
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2025-01-02 DOI: 10.1016/j.plrev.2025.01.001
Gui-Quan Sun , Li Li , Yan-Song Pei
{"title":"Advancing epidemic modeling: The role of LLMs and generative agent-based models Comment on LLMs and generative agent-based models for complex systems research by Lu et al.","authors":"Gui-Quan Sun ,&nbsp;Li Li ,&nbsp;Yan-Song Pei","doi":"10.1016/j.plrev.2025.01.001","DOIUrl":"10.1016/j.plrev.2025.01.001","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"52 ","pages":"Pages 175-177"},"PeriodicalIF":13.7,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142930445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on: “Data-driven mathematical modeling approaches for COVID-19: A survey” 评论:“COVID-19数据驱动的数学建模方法:调查”。
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2024-12-31 DOI: 10.1016/j.plrev.2024.12.014
Ousmane Seydi
{"title":"Comment on: “Data-driven mathematical modeling approaches for COVID-19: A survey”","authors":"Ousmane Seydi","doi":"10.1016/j.plrev.2024.12.014","DOIUrl":"10.1016/j.plrev.2024.12.014","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"52 ","pages":"Pages 171-172"},"PeriodicalIF":13.7,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patterns of neuronal synchrony in higher-order networks 高阶网络中神经元同步模式。
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2024-12-30 DOI: 10.1016/j.plrev.2024.12.013
Soumen Majhi , Samali Ghosh , Palash Kumar Pal , Suvam Pal , Tapas Kumar Pal , Dibakar Ghosh , Jernej Završnik , Matjaž Perc
{"title":"Patterns of neuronal synchrony in higher-order networks","authors":"Soumen Majhi ,&nbsp;Samali Ghosh ,&nbsp;Palash Kumar Pal ,&nbsp;Suvam Pal ,&nbsp;Tapas Kumar Pal ,&nbsp;Dibakar Ghosh ,&nbsp;Jernej Završnik ,&nbsp;Matjaž Perc","doi":"10.1016/j.plrev.2024.12.013","DOIUrl":"10.1016/j.plrev.2024.12.013","url":null,"abstract":"<div><div>Synchrony in neuronal networks is crucial for cognitive functions, motor coordination, and various neurological disorders. While traditional research has focused on pairwise interactions between neurons, recent studies highlight the importance of higher-order interactions involving multiple neurons. Both types of interactions lead to complex synchronous spatiotemporal patterns, including the fascinating phenomenon of chimera states, where synchronized and desynchronized neuronal activity coexist. These patterns are thought to resemble pathological states such as schizophrenia and Parkinson's disease, and their emergence is influenced by neuronal dynamics as well as by synaptic connections and network structure. This review integrates the current understanding of how pairwise and higher-order interactions contribute to different synchrony patterns in neuronal networks, providing a comprehensive overview of their role in shaping network dynamics. We explore a broad range of connectivity mechanisms that drive diverse neuronal synchrony patterns, from pairwise long-range temporal interactions and time-delayed coupling to adaptive communication and higher-order, time-varying connections. We cover key neuronal models, including the Hindmarsh-Rose model, the stochastic Hodgkin-Huxley model, the Sherman model, and the photosensitive FitzHugh-Nagumo model. By investigating the emergence and stability of various synchronous states, this review highlights their significance in neurological systems and indicates directions for future research in this rapidly evolving field.</div></div>","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"52 ","pages":"Pages 144-170"},"PeriodicalIF":13.7,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The controversial status of affect in the interplay between the body and the mind Comment on “The affective grounds of the mind. The affective pertinentization (APER) model” by S. Salvatore, A. Palmieri, R. De Luca Picione, V. Bochicchio, M. Reho, M. R. Serio, & G. Salvatore 情感在身心相互作用中的争议地位评析“心灵的情感基础”。情感针对性(APER)模型(S. Salvatore, A. Palmieri, R. De Luca picone, V. Bochicchio, M. Reho, M. R. Serio, & G. Salvatore)
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2024-12-26 DOI: 10.1016/j.plrev.2024.12.015
N. Gaj
{"title":"The controversial status of affect in the interplay between the body and the mind Comment on “The affective grounds of the mind. The affective pertinentization (APER) model” by S. Salvatore, A. Palmieri, R. De Luca Picione, V. Bochicchio, M. Reho, M. R. Serio, & G. Salvatore","authors":"N. Gaj","doi":"10.1016/j.plrev.2024.12.015","DOIUrl":"10.1016/j.plrev.2024.12.015","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"52 ","pages":"Pages 173-174"},"PeriodicalIF":13.7,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Building bidirectional, signed, and weighted interaction network among microbes 构建微生物间双向、签名、加权的相互作用网络——评Gong等人“全球变暖下森林恢复力的土壤微生物群网络拓扑变化”
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2024-12-19 DOI: 10.1016/j.plrev.2024.12.010
Tianchen Gao, Jingyuan Liu
{"title":"Building bidirectional, signed, and weighted interaction network among microbes","authors":"Tianchen Gao,&nbsp;Jingyuan Liu","doi":"10.1016/j.plrev.2024.12.010","DOIUrl":"10.1016/j.plrev.2024.12.010","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"52 ","pages":"Pages 178-179"},"PeriodicalIF":13.7,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A unified mechanism for interpreting the emotional content of voice, speech and music: Comment on “The major-minor mode dichotomy in music perception” by Carraturo et al. 解读声音、言语和音乐情感内容的统一机制:评Carraturo等人的“音乐感知中的大调-小调二分法”。
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2024-12-19 DOI: 10.1016/j.plrev.2024.12.012
Alice Mado Proverbio
{"title":"A unified mechanism for interpreting the emotional content of voice, speech and music: Comment on “The major-minor mode dichotomy in music perception” by Carraturo et al.","authors":"Alice Mado Proverbio","doi":"10.1016/j.plrev.2024.12.012","DOIUrl":"10.1016/j.plrev.2024.12.012","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"52 ","pages":"Pages 107-108"},"PeriodicalIF":13.7,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Words as social tools (WAT): A reprise 文字作为社会工具(WAT):重复。
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2024-12-19 DOI: 10.1016/j.plrev.2024.12.011
Claudia Mazzuca , Chiara Fini , Chiara De Livio , Ilenia Falcinelli , Fernando Maggio , Luca Tummolini , Anna M. Borghi
{"title":"Words as social tools (WAT): A reprise","authors":"Claudia Mazzuca ,&nbsp;Chiara Fini ,&nbsp;Chiara De Livio ,&nbsp;Ilenia Falcinelli ,&nbsp;Fernando Maggio ,&nbsp;Luca Tummolini ,&nbsp;Anna M. Borghi","doi":"10.1016/j.plrev.2024.12.011","DOIUrl":"10.1016/j.plrev.2024.12.011","url":null,"abstract":"<div><div>The paper presents new evidence collected in the last five years supporting the Words As social Tools proposal on abstract concepts. We discuss findings revolving around three central tenets. First, we show that—like concrete concepts—also abstract concepts evoke sensorimotor experiences, even if to a lower extent, and that they are linked to inner experiences (e.g., interoceptive, proprioceptive, and metacognitive). Second, we present findings suggesting that linguistic and social interaction are crucial for acquiring and using abstract concepts. Specifically, rating and behavioral studies reveal that people tend to feel uncertain about the meaning of abstract concepts. On top of that, with abstract concepts, people rely more on others to ask for information, negotiate conceptual meaning, or outsource their knowledge. We propose that inner speech might contribute both to the monitoring process and the preparation to interact with others. Finally, we illustrate recent studies conducted in our lab highlighting abstract concepts variability across individuals (age, expertise), cultures, and languages.</div></div>","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"52 ","pages":"Pages 109-128"},"PeriodicalIF":13.7,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142890926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PLRev at 20: Honoring Leonid Perlovsky and celebrating interdisciplinary science PLRev at 20:纪念列昂尼德·珀洛夫斯基,庆祝跨学科科学。
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2024-12-18 DOI: 10.1016/j.plrev.2024.12.008
José F. Fontanari , Ernesto Di Mauro , Maxim Frank-Kamenetskii
{"title":"PLRev at 20: Honoring Leonid Perlovsky and celebrating interdisciplinary science","authors":"José F. Fontanari ,&nbsp;Ernesto Di Mauro ,&nbsp;Maxim Frank-Kamenetskii","doi":"10.1016/j.plrev.2024.12.008","DOIUrl":"10.1016/j.plrev.2024.12.008","url":null,"abstract":"","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"52 ","pages":"Page 65"},"PeriodicalIF":13.7,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142870922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How proteins manage to fold and how chaperones manage to assist the folding 蛋白质如何折叠以及伴侣蛋白如何协助折叠。
IF 13.7 1区 生物学
Physics of Life Reviews Pub Date : 2024-12-15 DOI: 10.1016/j.plrev.2024.12.006
Sergiy O. Garbuzynskiy, Victor V. Marchenkov, Natalia Y. Marchenko, Gennady V. Semisotnov, Alexei V. Finkelstein
{"title":"How proteins manage to fold and how chaperones manage to assist the folding","authors":"Sergiy O. Garbuzynskiy,&nbsp;Victor V. Marchenkov,&nbsp;Natalia Y. Marchenko,&nbsp;Gennady V. Semisotnov,&nbsp;Alexei V. Finkelstein","doi":"10.1016/j.plrev.2024.12.006","DOIUrl":"10.1016/j.plrev.2024.12.006","url":null,"abstract":"<div><div>This review presents the current understanding of (i) spontaneous self-organization of spatial structures of protein molecules, and (ii) possible ways of chaperones’ assistance to this process. Specifically, we overview the most important features of spontaneous folding of proteins (mostly, of the single-domain water-soluble globular proteins): the choice of the unique protein structure among zillions of alternatives, the nucleation of the folding process, and phase transitions within protein molecules. We consider the main experimental facts on protein folding, both in vivo and in vitro, of both kinetic and thermodynamic nature. We discuss the famous Levinthal's paradox of protein folding and its solution, theoretical models of protein folding and unfolding, and the dependence of the rates of these processes on the protein chain length. Special attention is paid to relatively small, single-domain, and water-soluble globular proteins whose structure and folding are much better studied and understood than those of large proteins, especially membrane or fibrous proteins. Lastly, we describe the chaperone-assisted protein folding with an emphasis on the chaperones’ ability to prevent proteins from their irreversible aggregation. Since the possible assistance mechanisms connected with chaperones are still debatable, experimental data useful in selecting the most likely mechanisms of chaperone-assisted protein folding are presented.</div></div>","PeriodicalId":403,"journal":{"name":"Physics of Life Reviews","volume":"52 ","pages":"Pages 66-79"},"PeriodicalIF":13.7,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142875613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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