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Molecular Correlative Material Characterization: Advantages for Polymer Analysis Using Liquid Chromatography 分子相关材料表征:液相色谱分析聚合物的优势
LCGC Europe Pub Date : 2021-05-01 DOI: 10.56530/lcgc.eu.ez6278j8
R. Peters, B. Pirok, Y. Mengerink
{"title":"Molecular Correlative Material Characterization: Advantages for Polymer Analysis Using Liquid Chromatography","authors":"R. Peters, B. Pirok, Y. Mengerink","doi":"10.56530/lcgc.eu.ez6278j8","DOIUrl":"https://doi.org/10.56530/lcgc.eu.ez6278j8","url":null,"abstract":"This article discusses innovation around the molecular structure of polymeric materials—an indispensable part of modern society—with a specific focus on sustainability. This field of research, so-called molecular correlative material characterization (MCMC), will enhance the transition into new sustainable functional copolymers.","PeriodicalId":402085,"journal":{"name":"LCGC Europe","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125346690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Clinical Metabolomics: Expanding the Metabolome Coverage Using Advanced Analytical Techniques 临床代谢组学:利用先进的分析技术扩大代谢组学的覆盖范围
LCGC Europe Pub Date : 2019-09-01 DOI: 10.56530/lcgc.eu.ry4267t3
R. Haselberg, B. Pirok, Andrea F. G. Gargano, Isabelle Kohler
{"title":"Clinical Metabolomics: Expanding the Metabolome Coverage Using Advanced Analytical Techniques","authors":"R. Haselberg, B. Pirok, Andrea F. G. Gargano, Isabelle Kohler","doi":"10.56530/lcgc.eu.ry4267t3","DOIUrl":"https://doi.org/10.56530/lcgc.eu.ry4267t3","url":null,"abstract":"This review article discusses the novel separation and detection strategies that are considered promising in clinical metabolomics to enhance the metabolome coverage. It includes hydrophilic interaction chromatography (HILIC), supercritical fluid chromatography (SFC), multidimensional LC approaches, as well as ion-mobility mass spectrometry (IM-MS) and data-independent acquisition (DIA) analysis methods.","PeriodicalId":402085,"journal":{"name":"LCGC Europe","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133030230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Practical Approaches to Overcome the Challenges of Comprehensive Two-Dimensional Liquid Chromatography 克服综合二维液相色谱挑战的实用方法
LCGC Europe Pub Date : 2018-05-01 DOI: 10.56530/lcgc.eu.dy3481z3
B. Pirok, P. Schoenmakers
{"title":"Practical Approaches to Overcome the Challenges of Comprehensive Two-Dimensional Liquid Chromatography","authors":"B. Pirok, P. Schoenmakers","doi":"10.56530/lcgc.eu.dy3481z3","DOIUrl":"https://doi.org/10.56530/lcgc.eu.dy3481z3","url":null,"abstract":"Comprehensive two-dimensional liquid chromatography (LC×LC) is a powerful technique for separating highly complex samples. However, the proliferation of this technique is hindered by a range of challenges, including the possible impact of the additional separation on the detection sensitivity, concerns that mobile phase incompatibility problems will limit the applicability, and the complexity of the system and associated method development costs. This article addresses these issues and describes how modern modulators and software tools are overcoming the barriers associated with this technique.","PeriodicalId":402085,"journal":{"name":"LCGC Europe","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131086373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
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