Clinical Metabolomics: Expanding the Metabolome Coverage Using Advanced Analytical Techniques

LCGC Europe Pub Date : 2019-09-01 DOI:10.56530/lcgc.eu.ry4267t3

R. Haselberg, B. Pirok, Andrea F. G. Gargano, Isabelle Kohler

引用次数: 3

Abstract

This review article discusses the novel separation and detection strategies that are considered promising in clinical metabolomics to enhance the metabolome coverage. It includes hydrophilic interaction chromatography (HILIC), supercritical fluid chromatography (SFC), multidimensional LC approaches, as well as ion-mobility mass spectrometry (IM-MS) and data-independent acquisition (DIA) analysis methods.

查看原文本刊更多论文

临床代谢组学:利用先进的分析技术扩大代谢组学的覆盖范围

这篇综述文章讨论了在临床代谢组学中被认为有前途的新的分离和检测策略，以提高代谢组学的覆盖率。它包括亲水性相互作用色谱(HILIC)，超临界流体色谱(SFC)，多维LC方法，以及离子迁移率质谱(IM-MS)和数据独立采集(DIA)分析方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

LCGC Europe

自引率

0.00%

发文量