Kurume Medical Journal最新文献_第2页

Developmental and Healing Processes of Uterine Artery Pseudoaneurysm After Non-Traumatic Delivery Followed by Transarterial Embolism: Sequential Observations in a Case Depicting Using Superb Microvascular Imaging. 非创伤性分娩后经动脉栓塞后子宫动脉假性动脉瘤的发育和愈合过程：一个使用高超微血管成像的病例的连续观察。

Kurume Medical Journal Pub Date : 2026-08-21 DOI: 10.2739/kurumemedj.MS7312002

Megumi Muto, Yusuke Kurokawa, Asako Kuhara, Takashi Horinouchi, Masato Yokomine, Toshiyuki Yoshizato, Naotake Tsuda

{"title":"Developmental and Healing Processes of Uterine Artery Pseudoaneurysm After Non-Traumatic Delivery Followed by Transarterial Embolism: Sequential Observations in a Case Depicting Using Superb Microvascular Imaging.","authors":"Megumi Muto, Yusuke Kurokawa, Asako Kuhara, Takashi Horinouchi, Masato Yokomine, Toshiyuki Yoshizato, Naotake Tsuda","doi":"10.2739/kurumemedj.MS7312002","DOIUrl":"https://doi.org/10.2739/kurumemedj.MS7312002","url":null,"abstract":"We report a case of uterine artery pseudoaneurysm in which the developmental process of pseudoaneurysm was, for the first time to our knowledge, depicted using superb microvascular imaging (SMI). The patient became pregnant naturally and had an uneventful pregnancy. At 41 weeks of gestation, she spontaneously delivered a neonate and placenta, which had been attached to the posterior uterine wall. On the seventh postpartum day, SMI demonstrated a flow signal measuring 3×12 mm running straight through the posterior myometrium perpendicular to the endometrium, suggesting dilation of the radial artery. On the eighth postpartum day there was a moderate amount of vaginal bleeding. Color Doppler ultrasonography showed turbulent flow measuring 8 mm in diameter, located in the same posterior myometrial location as found on the previous day and bulging into the cavity. This finding indicated an uterine artery pseudoaneurysm, which was confirmed by pelvic arterial angiography. A follow-up SMI, three days after embolization, revealed the absence of the pseudoaneurysm, and normal radial arterial flows were restored by the 13th day after embolization.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148808996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congenital Absence of the Left Common Iliac Artery: A Case Report. 先天性左髂总动脉缺失1例。

Kurume Medical Journal Pub Date : 2026-08-21 DOI: 10.2739/kurumemedj.MS7312005

Suzuka Watanabe, Yoko Tabira, Joe Iwanaga, Rarinthorn Samrid, Seiichi Inoue, Hisashi Nakamura, R Shane Tubbs, Koichi Watanabe

引用次数: 0

Left Inferior Vena Cava: A Cadaver Case Report. 左下腔静脉：1例尸体报告。

Kurume Medical Journal Pub Date : 2026-07-01 Epub Date: 2026-01-29 DOI: 10.2739/kurumemedj.MS721234001

Yoko Tabira, Joe Iwanaga, Aya Han, Seiichi Inoue, Kunimitsu Nooma, Yuto Haikata, Tsuyoshi Saga, R Shane Tubbs, Koichi Watanabe

引用次数: 0

Twelve-month Retrospective Comparison of Modified Treat-and-Extend and Pro Re Nata Regimens of Intravitreal Aflibercept for Macular Edema Secondary to Branch Retinal Vein Occlusion. 玻璃体内注射阿非利赛普治疗视网膜分支静脉闭塞继发黄斑水肿的改良治疗延长方案与原方案12个月回顾性比较。

Kurume Medical Journal Pub Date : 2026-07-01 Epub Date: 2026-05-15 DOI: 10.2739/kurumemedj.MS721234015

Rikki Arai, Kazunori Sato, Nobuhiro Kato, Kei Furushima, Akito Nagae, Yusho Koyanagi, Junichi Itou, Masatoshi Haruta, Shigeo Yoshida

{"title":"Twelve-month Retrospective Comparison of Modified Treat-and-Extend and Pro Re Nata Regimens of Intravitreal Aflibercept for Macular Edema Secondary to Branch Retinal Vein Occlusion.","authors":"Rikki Arai, Kazunori Sato, Nobuhiro Kato, Kei Furushima, Akito Nagae, Yusho Koyanagi, Junichi Itou, Masatoshi Haruta, Shigeo Yoshida","doi":"10.2739/kurumemedj.MS721234015","DOIUrl":"10.2739/kurumemedj.MS721234015","url":null,"abstract":"Purpose: To compare the clinical efficacy and treatment burden between a modified treat-and-extend (mTAE) regimen and a pro re nata (PRN) regimen of intravitreal aflibercept in patients with macular edema (ME) secondary to branch retinal vein occlusion (BRVO).Methods: This retrospective study included 17 eyes in 17 treatment-naïve patients with BRVO-associated ME who received intravitreal aflibercept at Kurume University Hospital. Patients were assigned to either the mTAE group (n=9) or the PRN group (n=8). The primary outcomes were the changes in best-corrected visual acuity (BCVA) and central macular thickness (CMT) over 12 months. The secondary outcomes included the numbers of injections and clinic visits.Results: Mean BCVA improved by 9 ETDRS letters in the mTAE group and 6 letters in the PRN group at 12 months. Both groups achieved significant improvements in CMT at 12 months, with no significant differences between the two groups. The mean number of injections was 5.1±1.5 in the mTAE group and 3.8±1.6 in the PRN group (p=0.14). However, the mTAE group had significantly fewer clinic visits than the PRN group (8.0±1.6 vs. 10.9±3.0; p=0.04). No serious adverse events were observed in either group.Conclusion: Both the mTAE and PRN regimens of intravitreal aflibercept effectively reduced ME in BRVO patients over 12 months. However, the mTAE approach significantly reduced the frequency of clinic visits without compromising the efficacy, suggesting that it may be less burdensome for patients and clinics for the management of BRVO-ME in real-world practice. These findings support the use of an individualized treat-and-extend strategy to maintain clinical benefits while alleviating the treatment burden in BRVO patients.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":" ","pages":"83-89"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147964882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lobularity in Autoimmune Pancreatitis Was A Steroid-Therapy Responding Endoscopic Ultrasound Finding. 自身免疫性胰腺炎的小叶性是一种类固醇治疗的内镜超声发现。

Kurume Medical Journal Pub Date : 2026-07-01 Epub Date: 2026-01-29 DOI: 10.2739/kurumemedj.MS721234002

Yutaka Shimamatsu, Yoshinobu Okabe, Shingo Hirai, Hiroya Terabe, Yoshiki Naito, Tomoyuki Ushijima, Makiko Yasumoto, Hideya Suga, Y U Sasaki, Takumi Kawaguchi

{"title":"Lobularity in Autoimmune Pancreatitis Was A Steroid-Therapy Responding Endoscopic Ultrasound Finding.","authors":"Yutaka Shimamatsu, Yoshinobu Okabe, Shingo Hirai, Hiroya Terabe, Yoshiki Naito, Tomoyuki Ushijima, Makiko Yasumoto, Hideya Suga, Y U Sasaki, Takumi Kawaguchi","doi":"10.2739/kurumemedj.MS721234002","DOIUrl":"https://doi.org/10.2739/kurumemedj.MS721234002","url":null,"abstract":"Background and aims: Endoscopic ultrasound (EUS) can evaluate morphological changes in various pancreatic diseases. We aimed to identify changes in EUS findings of autoimmune pancreatitis (AIP) in response to steroid therapy.Methods: We enrolled 37 patients with AIP and performed EUS before and 2 weeks after steroid therapy to evaluate EUS findings in response to the therapy. Furthermore, we compared the EUS and histopathological findings on AIP in 2 patients who underwent pancreatectomy.Results: The EUS findings revealed no significant changes in the prevalence of hyperechoic strands and hypoechoic swelling 2 weeks after steroid therapy. In contrast, the prevalence of lobularity significantly decreased from 48.6% to 21.6% after steroid therapy, with a more pronounced reduction in focal AIP (63.6% to 18.2%). Histopathological analysis revealed that lobularity was corresponded to storiform fibrosis between lobular structures infiltrated with immunoglobulin G4-positive plasma cells.Conclusion: Lobularity in AIP was the most responsive EUS finding to the steroid therapy. Focal lobularity was corresponded to storiform fibrosis between lobular structures infiltrated by IgG4-positive plasma cells. Thus, our findings might help elucidate the pathogenesis of AIP that is responsive to steroid therapy.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":"72 1.2.3.4","pages":"21-27"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148370337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examination of Inferior Mesenteric Artery Node Metastasis in Left-Sided Colorectal Cancer: A Retrospective Cohort Analysis. 左侧结直肠癌肠系膜下动脉结转移的检查：回顾性队列分析。

Kurume Medical Journal Pub Date : 2026-07-01 Epub Date: 2026-03-27 DOI: 10.2739/kurumemedj.MS721-4009

Takefumi Yoshida, Dai Shida, Kenta Murotani, Kenichi Koushi, Naohiro Yoshida, Kenji Fujiyoshi, Takahiro Shigaki, Tomoya Sudou, Yoshito Akagi, Fumihiko Fujita

{"title":"Examination of Inferior Mesenteric Artery Node Metastasis in Left-Sided Colorectal Cancer: A Retrospective Cohort Analysis.","authors":"Takefumi Yoshida, Dai Shida, Kenta Murotani, Kenichi Koushi, Naohiro Yoshida, Kenji Fujiyoshi, Takahiro Shigaki, Tomoya Sudou, Yoshito Akagi, Fumihiko Fujita","doi":"10.2739/kurumemedj.MS721-4009","DOIUrl":"10.2739/kurumemedj.MS721-4009","url":null,"abstract":"Purpose: Inferior mesenteric artery node (IMAN) metastasis is rare in left-sided colorectal cancer. Tumor depth is a risk factor for IMAN metastasis, but other risk factors are unclear. This study investigated the frequency of IMAN metastasis and examined clinicopathological risk factors associated with this metastasis in left-sided colorectal cancer. We also aimed to evaluate the clinical benefit of routine D3 lymphadenectomy in surgically treated advanced colorectal cancer.Methods: We retrospectively studied patients with colorectal cancer who underwent D3 lymphadenectomy and R0 resection at Kurume University Hospital from 1996 to 2017 to identify the frequency and risk factors for IMAN metastasis to investigate the long-term prognosis. Clinicopathological factors associated with IMAN metastasis were analyzed.Results: Among 949 consecutive patients, IMAN metastasis was observed in 8 (0.84%) patients. The 5-year overall survival rate was significantly lower in the IMAN metastasis-positive group (68.6%) than in the IMAN metastasis-negative group (83.7%) (p = 0.025).Conclusion: IMAN metastasis is a poor prognostic factor for left-sided colorectal cancer, but this metastasis has a 5-year survival rate of 68.6%.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":" ","pages":"39-48"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147575621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical Approach to Primary Cardiac Malignant Lymphoma Considering Early Initiation of Chemotherapy. 考虑早期化疗的原发性心脏恶性淋巴瘤手术入路。

Kurume Medical Journal Pub Date : 2026-07-01 Epub Date: 2026-03-19 DOI: 10.2739/kurumemedj.MS721-4008

Hiroyuki Saisho, Satoru Tobinaga, Yusuke Shintani, Hiroshi Yasunaga

{"title":"Surgical Approach to Primary Cardiac Malignant Lymphoma Considering Early Initiation of Chemotherapy.","authors":"Hiroyuki Saisho, Satoru Tobinaga, Yusuke Shintani, Hiroshi Yasunaga","doi":"10.2739/kurumemedj.MS721-4008","DOIUrl":"10.2739/kurumemedj.MS721-4008","url":null,"abstract":"A 67-year-old woman was referred for cardiac tumor. Computed tomography scans revealed a large mass occupying the left atrium causing the left pulmonary vein obstruction and pulmonary congestion. Positron emission tomography / computed tomography (PET/CT) showed abnormal accumulation at the border between the left atrium and the left pulmonary vein orifices, and the invasion of the malignant cell to the left upper and lower pulmonary veins was highly suspected. Operative finding was that the tumor was attached to the left atrial posterior wall adjacent to the left pulmonary vein orifices and extended to the left upper pulmonary vein about 1 cm beyond the left upper pulmonary vein orifice. The tumor was not extended to the left lower pulmonary vein. Considering the possibility that the tumor was a sarcoma, for which chemotherapy was less effective, radical resection including left upper lobectomy and reconstruction of the left atrium was considered, but a rapid intra-operative histological exam revealed a malignant lymphoma. Therefore, surgery was performed to reduce the tumor as much as possible. The postoperative course was good and the patient was treated with chemotherapy, surviving for 18 months without any signs of recurrence.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":" ","pages":"125-128"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147481930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effects of Hyperbaric Oxygen Therapy in Postoperative Patients with Ulcerative Colitis: A Retrospective Study. 高压氧治疗对溃疡性结肠炎术后患者的影响：一项回顾性研究。

Kurume Medical Journal Pub Date : 2026-07-01 Epub Date: 2026-01-29 DOI: 10.2739/kurumemedj.MS721234005

Daisuke Muroya, Shinya Nadayoshi, Koito Yamada, Yutaro Kai, Tetsu Masuda, Daiki Miyazaki, Shin Sasaki, Hisaaki Shimokobe, Hisao Shimokobe, Kenji Okamoto, Toshiki Hiramatsu, Masao Inoue, Takeshi Konno, Kohji Okamoto

{"title":"The Effects of Hyperbaric Oxygen Therapy in Postoperative Patients with Ulcerative Colitis: A Retrospective Study.","authors":"Daisuke Muroya, Shinya Nadayoshi, Koito Yamada, Yutaro Kai, Tetsu Masuda, Daiki Miyazaki, Shin Sasaki, Hisaaki Shimokobe, Hisao Shimokobe, Kenji Okamoto, Toshiki Hiramatsu, Masao Inoue, Takeshi Konno, Kohji Okamoto","doi":"10.2739/kurumemedj.MS721234005","DOIUrl":"https://doi.org/10.2739/kurumemedj.MS721234005","url":null,"abstract":"Objectives: Numerous clinical trials have proven that hyperbaric oxygen therapy (HBOT) is an effective adjunctive treatment for inflammatory bowel disease (IBD). The present study evaluated the effect of HBOT in patients with postoperative ulcerative colitis (UC).Methods: This retrospective study examined the effects of HBOT on short-term postoperative outcomes in patients with UC. This study included 21 patients with postoperative UC between January 2013 and December 2023. Of these, six patients received HBOT; the previous indication for HBOT was postoperative ileus. The nutritional status, inflammatory findings, and disease severity scores were evaluated during the one-month post-operative period.Results: In the univariate analysis, the mean age was higher in the non-HBOT group than in the HBOT group (54.3 vs. 64.9 years old, p=0.0461), although the operative details and severity did not differ markedly. The usefulness of the Controlling Nutritional Status (CONUT) score as a nutritional screening and predictive tool has been demonstrated for various inflammatory and neoplastic diseases, including UC. The CONUT score was inversely correlated with Onodera's prognostic nutritional index and positively correlated with the platelet count, C-reactive protein level, and erythrocyte sedimentation rate. In addition, the HBOT group had a lower CONUT score 1 month after surgery than the non-HBOT group (2.0 vs. 4.4, p= 0.0190).Conclusions: Postoperative UC patients who received HBOT had better CONUT scores at 1 month compared to those who did not.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":"72 1.2.3.4","pages":"13-19"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148370257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Focal Fatty Change After Total Pancreatectomy Mimics Hypervascular Liver Tumor. 全胰切除术后局灶性脂肪改变模拟高血管性肝肿瘤。

Kurume Medical Journal Pub Date : 2026-07-01 Epub Date: 2026-03-27 DOI: 10.2739/kurumemedj.MS721-4007

Shusuke Okamura, Takeshi Aoyagi, Koichi Higaki, Yusuke Nakamura, Kohei Ota, Yusuke Aoki, Hiromasa Watanabe, Wataru Fukami, Sho Shibata, Erina Ueno, Hiroshi Kawano, Keiichi Mitsuyama, Osamu Tsuruta, Takumi Kawaguchi

引用次数: 0

Development of Machine Learning Models to Predict Candidemia in Hospitalized Adult Patients. 机器学习模型在住院成人患者中预测念珠菌的发展。

Kurume Medical Journal Pub Date : 2026-07-01 Epub Date: 2026-05-15 DOI: 10.2739/kurumemedj.MS721234017

Kenyu Hashimoto, Koutarou Matsumoto, Kenta Murotani

{"title":"Development of Machine Learning Models to Predict Candidemia in Hospitalized Adult Patients.","authors":"Kenyu Hashimoto, Koutarou Matsumoto, Kenta Murotani","doi":"10.2739/kurumemedj.MS721234017","DOIUrl":"10.2739/kurumemedj.MS721234017","url":null,"abstract":"Purpose: We aimed to develop a generalizable machine learning model that leverages electronic medical record (EMR) data to predict candidemia using information available on or before the date of blood culture collection.Methods: This study included adult patients admitted to Shin Koga Hospital (April 2014-March 2022) who underwent blood cultures at least 14 days after admission. We prepared two datasets: a \"Complete case dataset\" (13 variables, no missing values) and a \"Imputed full-variable dataset\" (36 variables, single imputation). We evaluated the discriminative performance of four machine learning models, including extreme gradient boosting, random forest, least absolute shrinkage and selection operator (LASSO) logistic regression, and logistic regression using stratified 5-fold cross-validation by comparing their area under the receiver operating characteristic curve (AUROC). The model with the highest mean AUROC was selected, assessed on the entire dataset, and internally validated using 1,000 bootstrap replicates.Results: A total of 919 patients were included, of whom 47 (5.1%) had candidemia. The LASSO logistic regression demonstrated the best performance and was selected as the final model. The AUROC (95% CI) was 0.880 (0.836-0.924) for the Complete case dataset and 0.913 (0.878-0.948) for the Imputed full-variable dataset. The optimism-corrected AUROCs were 0.851 and 0.876, respectively.Conclusion: We developed two versions of the LASSO logistic regression model using only information automatically extracted from EMR, considering real-world data availability. These models have the potential to serve as practical tools to support early diagnosis and therapeutic intervention for candidemia.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":" ","pages":"91-102"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147964926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0