Kurume Medical Journal最新文献

Anatomical Variations of the Iliopsoas Muscle. 髂腰肌的解剖变异。

Kurume Medical Journal Pub Date : 2025-06-13 DOI: 10.2739/kurumemedj.MS7134010

Yoko Tabira, Joe Iwanaga, Aya Han, Seiichi Inoue, Tatsuya Harano, Keigo Shimizu, Mitsuru Tanaka, R Shane Tubbs, Koichi Watanabe

{"title":"Anatomical Variations of the Iliopsoas Muscle.","authors":"Yoko Tabira, Joe Iwanaga, Aya Han, Seiichi Inoue, Tatsuya Harano, Keigo Shimizu, Mitsuru Tanaka, R Shane Tubbs, Koichi Watanabe","doi":"10.2739/kurumemedj.MS7134010","DOIUrl":"https://doi.org/10.2739/kurumemedj.MS7134010","url":null,"abstract":"Anatomical variations of the iliopsoas muscle are relatively uncommon but are clinically significant because of the muscle's relation to the femoral nerve (FN). Variants of the iliopsoas include accessory iliacus, iliacus minimus, psoas tertius, and psoas quartus muscles. This study describes anatomical findings of these variants. Dissections of the posterior abdominal wall in 95 Japanese cadavers at Kurume University School of Medicine (2015-2017) identified three cases of iliopsoas muscle variants. In the first case, a small variant muscle on the right side of a 91-year-old female cadaver originated from the iliolumbar ligament, pierced the FN, and joined the psoas major muscle (PMa). In the second case, a variant muscular slip was identified on the left side of a 78-year-old female cadaver. The slip originated from the anterior aspect of the middle part of the iliac crest and pierced the FN. The muscle joined the tendon of the PMa. Both cases were categorized as variations of the iliacus muscle (IM) and were called iliacus minimus muscles. In the third case, a bilateral variant muscle was noted in a 74-year-old male cadaver. The muscles mainly originated from the surface of the quadratus lumborum muscle. The variant muscle called the psoas quartus muscle, traveled posterior to the FN and united with the normal PMa and IM. This variation is seemingly very rare. A thorough understanding of these morphologic variations is essential for the accurate diagnosis and treatment of femoral nerve disorders and for safe lumbar and abdominal surgery.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of Thyrotoxicosis With Positive TSH Receptor Antibody and Transition to Hypothyroidism in a Patient With Unresectable Hepatocellular Carcinoma During Combined Atezolizumab and Bevacizumab Therapy: A Case Report and Review of the Literature. 在阿特唑单抗和贝伐单抗联合治疗期间，不可切除的肝癌患者发展为TSH受体抗体阳性的甲状腺毒症并过渡到甲状腺功能减退：1例报告和文献回顾

Kurume Medical Journal Pub Date : 2025-06-13 DOI: 10.2739/kurumemedj.MS7134008

Ryutaro Hidaka, Yuji Hiromatsu, Narihito Tatsumoto, Takahiro Fukuyama, Yoko Sagara, Aira Uchida, Hidekazu Tamai, Masayuki Tojikubo, Yuko Akehi, Eiji Kawasaki, Hiroki Nakamura

{"title":"Development of Thyrotoxicosis With Positive TSH Receptor Antibody and Transition to Hypothyroidism in a Patient With Unresectable Hepatocellular Carcinoma During Combined Atezolizumab and Bevacizumab Therapy: A Case Report and Review of the Literature.","authors":"Ryutaro Hidaka, Yuji Hiromatsu, Narihito Tatsumoto, Takahiro Fukuyama, Yoko Sagara, Aira Uchida, Hidekazu Tamai, Masayuki Tojikubo, Yuko Akehi, Eiji Kawasaki, Hiroki Nakamura","doi":"10.2739/kurumemedj.MS7134008","DOIUrl":"https://doi.org/10.2739/kurumemedj.MS7134008","url":null,"abstract":"A 65-year-old male with multiple hepatocellular carcinomas underwent hepatic artery chemoembolization in March X and was administered lenvatinib. In July X, 2 weeks after the initiation of this treatment, he developed latent hypothyroidism. However, he showed no response to these treatments. Consequently, a combination therapy consisting of an anti-programmed cell death protein-ligand 1 (PD-L1) antibody (atezolizumab) plus bevacizumab, administered every 3 weeks, was initiated in March X+1. During three cycles of this combination therapy, the patient developed thyrotoxicosis. Graves' disease (GD) was suspected by TSH receptor antibody (TRAb) positivity and diffuse uptake in thyroid scintigraphy, although 99mTcO4- uptake was normal. He was treated with methimazole. Notably, the hyperthyroidism was transient, rapidly transitioning to hypothyroidism. The emergence of GD during treatment with immune checkpoint inhibitors (ICPi) is a rare occurrence. To date, 26 cases of new-onset GD and/or thyroid eye disease (TED) have been reported. Approximately 71% of patients develop GD and/or TED within 3 months following the initiation of ICPi treatment. They quickly transition to a hypothyroid state, necessitating levothyroxine therapy. Furthermore, the presence of thyroid autoantibodies at baseline has been identified as a significant risk factor for thyroid immune-related adverse events (irAEs), highlighting the need for baseline measurements of these autoantibodies before treatment. Future prospective studies and further case report accumulations are essential to elucidate the role of thyroid irAEs during the combined therapy of ICPi and molecularly targeted drugs in advanced carcinoma cases.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing Delirium Incidence and Length of Stay in Cardiovascular Procedures Before and After Coronavirus Disease 2019 Family Visitation Restrictions: A Single-Center Cohort Study. 比较2019冠状病毒病家庭探视限制前后心血管手术中谵妄发生率和住院时间：一项单中心队列研究

Kurume Medical Journal Pub Date : 2025-06-13 DOI: 10.2739/kurumemedj.MS7134009

Jun Kawabata, Kotaro Kuwaki, Tohru Takaseya, Naoki Itaya, Shinichi Tanihara

{"title":"Comparing Delirium Incidence and Length of Stay in Cardiovascular Procedures Before and After Coronavirus Disease 2019 Family Visitation Restrictions: A Single-Center Cohort Study.","authors":"Jun Kawabata, Kotaro Kuwaki, Tohru Takaseya, Naoki Itaya, Shinichi Tanihara","doi":"10.2739/kurumemedj.MS7134009","DOIUrl":"https://doi.org/10.2739/kurumemedj.MS7134009","url":null,"abstract":"Background: The impact of visitation restrictions due to the coronavirus disease (COVID-19) pandemic remains uncertain. This study examined delirium incidence and length of hospital stay of patients who underwent coronary artery bypass grafting, percutaneous coronary intervention, and transcatheter aortic valve implantation before and after visitation restrictions.Methods: The visitation restriction group (RG) included patients admitted and discharged between April 1, 2020, and March 31, 2022, whereas the non-restriction group (Non-RG) included those between April 1, 2018, and March 31, 2020. A chi-square test and sensitivity analysis were conducted to compare delirium incidence. The Mann-Whitney U test was used to compare the median length of stay. We conducted a multivariate logistic regression analysis to examine the association between delirium incidence and visitation restrictions and performed a subgroup analysis.Results: There was no significant difference in delirium incidence between Non-RG and RG (0.7% vs. 2.1%, P=0.083), as supported by the sensitivity analysis (3.3% vs. 2.1%, P=0.29). The length of stay significantly differed between Non-RG and RG (14 vs. 16 days, P=0.021). The odds ratios for delirium incidence, visitation restriction, emergency admission, and daily living level II were 2.46 (1.11-5.84), 3.65 (1.65-8.31), and 18.2 (3.45- 78.8), respectively. In the subgroup analysis, increase in sleep medications and discharge support were observed in high-risk patients.Conclusion: The analyses revealed no significant differences in delirium incidence between Non-RG and RG; however, the length of stay slightly increased. Delirium support and strategies for patient well-being during a pandemic are warranted.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pulmonary Metastasis after Resection for Gastrointestinal Stromal Tumor in the Rectum. 直肠胃肠道间质瘤切除术后肺转移。

Kurume Medical Journal Pub Date : 2025-06-13 DOI: 10.2739/kurumemedj.MS7134003

Seiko Harada, Shinzo Takamori, Daigo Murakami, Yusuke Uchida, Masaki Kashihara, Fumihiko Fujita, Takefumi Yoshida, Kenichi Koushi, Toshihiro Hashiguchi, Masahiro Mitsuoka, Yoshito Akagi

{"title":"Pulmonary Metastasis after Resection for Gastrointestinal Stromal Tumor in the Rectum.","authors":"Seiko Harada, Shinzo Takamori, Daigo Murakami, Yusuke Uchida, Masaki Kashihara, Fumihiko Fujita, Takefumi Yoshida, Kenichi Koushi, Toshihiro Hashiguchi, Masahiro Mitsuoka, Yoshito Akagi","doi":"10.2739/kurumemedj.MS7134003","DOIUrl":"https://doi.org/10.2739/kurumemedj.MS7134003","url":null,"abstract":"A 71-year-old woman who had received resection for gastrointestinal stromal tumor (GIST) in the rectum after imatinib mesylate administration, revealed a pulmonary nodule measuring 11 × 10 mm in the right lung on chest computed tomography (CT), which was 26 months after the operation. The pulmonary nodule had gradually increased to 13 × 13 mm in diameter on follow-up chest CT. The standardized uptake value (SUV) of the pulmonary nodule on positron emission tomogram (PET) with 2-fluoro-2-deoxy-D-glucose (FDG) was 1.8. For diagnostic and therapeutic purposes, thoracoscopic partial resection of the lung, including the nodule, was performed. The pathological findings showed pulmonary metastasis from rectal GIST. On immunohistochemical examination, the tumor was diagnosed as the high-risk group, whereas the primary site in the rectum was the lowrisk group according to the Modified Fletcher classification. Imatinib mesylate was administered again, but her disease progressed. Although pulmonary metastasis from rectal GIST is a rare disease with a possible poor prognosis, pathological diagnosis should be essential to deciding treatment modality.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rectal Metastasis from Early-Stage Endometrial Carcinoma Not Associated with Endometriosis: A Case Report and Literature Review. 与子宫内膜异位症无关的早期子宫内膜癌直肠转移一例报告并文献复习。

Kurume Medical Journal Pub Date : 2025-06-13 DOI: 10.2739/kurumemedj.MS7134005

Blagica Krsteska, Vladimir Risteski, Ana Jovceva, Svetozar Antovic

{"title":"Rectal Metastasis from Early-Stage Endometrial Carcinoma Not Associated with Endometriosis: A Case Report and Literature Review.","authors":"Blagica Krsteska, Vladimir Risteski, Ana Jovceva, Svetozar Antovic","doi":"10.2739/kurumemedj.MS7134005","DOIUrl":"https://doi.org/10.2739/kurumemedj.MS7134005","url":null,"abstract":"Objective: Endometrial cancer (EC) is the third most common malignancy in woman with excellent prognosis when diagnosed in early-stage. Recurrences are extremely rare in Stage I EC especially in rectum when not associated with endometriosis. We present a case of rectal metastasis from endometrial carcinoma after 8 years of primary diagnosis. A review of the literature showed only 6 published cases.Case presentation: Herein we present a 59-year-old woman with a rectal tumor mass. The patient before 8 years was surgically treated for EC Stage IA with bilateral salpingo-oophorectomy and hysterectomy. After ultra-low anterior resection rectum was removed with the tumor. Histology revealed adenocarcinoma with positive immunohistochemistry for CK7, ER, PAX8, Vimentin which confirmed endometrial origin. Endometriosis was not found.Conclusion: Although rectum is a rare site of recurrence from endometrial cancer, rectal tumors should be sampled carefully. Previous patient history and positive immunohistochemistry for EC are in favor of recurrent disease. Screening of colorectal carcinoma should be performed in patients with previous gynecologic diagnosis. Further genetic analysis in bigger case series is needed in order to explain the time and the site of recurrence of early-stage endometrial carcinoma.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Painful Os Peroneum Syndrome: An Unusual Diagnosis. 腓骨肌疼痛综合征：一个不寻常的诊断。

Kurume Medical Journal Pub Date : 2025-06-13 DOI: 10.2739/kurumemedj.MS7134006

Pedro Henrique Segatt, José Luiz Masson DE Almeida Prado, Márcio Luís Duarte

{"title":"Painful Os Peroneum Syndrome: An Unusual Diagnosis.","authors":"Pedro Henrique Segatt, José Luiz Masson DE Almeida Prado, Márcio Luís Duarte","doi":"10.2739/kurumemedj.MS7134006","DOIUrl":"https://doi.org/10.2739/kurumemedj.MS7134006","url":null,"abstract":"The painful Os peroneum syndrome is subdivided into acute and chronic cases. The acute presentation is usually caused by trauma, most commonly a supination or inversion of the ankle, which consequently can lead to a fracture of the Os peroneum or even a rupture of the peroneus longus tendon. Furthermore, its chronic presentation comes as a result of recurrent foot injuries or even recovery from a fracture with calcification remodeling of this sesamoid bone. The problem of underdiagnosing this disease lies in the consequences attached to the remodeling of the peroneus longus tendon with its calcification, or even leading to a picture of tenosynovitis and subsequent tendon rupture. We report a 55-year-old female patient who complains of pain in the lateral region of her right foot for ten days. The right foot X-ray detected the presence of \"Os peroneum.\" Magnetic resonance imaging (MRI) shows edematous ossification in the peroneus longus tendon compatible with Os peroneum and with swelling of the surrounding soft tissue and tendinopathy of the peroneus longus, precisely in the region indicated by the skin marker. The set of findings is compatible with painful Os peroneum syndrome. The patient was treated with a non-steroidal anti-inflammatory for five days with the resolution of symptoms.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral Persistent Sciatic Veins: A Cadaveric Case Report. 双侧持续性坐骨静脉：1例尸体报告。

Kurume Medical Journal Pub Date : 2025-04-18 DOI: 10.2739/kurumemedj.MS7134004

Renna Higa, Aya Han, Yoko Tabira, Keishiro Kikuchi, Kunimitsu Nooma, Tatsuya Harano, Keigo Shimizu, Eiko Inoue, Yuto Haikata, Joe Iwanaga, Tsuyoshi Saga, Koichi Watanabe

{"title":"Bilateral Persistent Sciatic Veins: A Cadaveric Case Report.","authors":"Renna Higa, Aya Han, Yoko Tabira, Keishiro Kikuchi, Kunimitsu Nooma, Tatsuya Harano, Keigo Shimizu, Eiko Inoue, Yuto Haikata, Joe Iwanaga, Tsuyoshi Saga, Koichi Watanabe","doi":"10.2739/kurumemedj.MS7134004","DOIUrl":"https://doi.org/10.2739/kurumemedj.MS7134004","url":null,"abstract":"We encountered a cadaver with bilateral persistent sciatic veins (PSVs) in the anatomical dissection course at our institution. Although PSV is associated with Klippel-Tranaunay syndrome, there were no other findings typical of the syndrome in this case. The PSVs on each side differed. On the left, the PSV ascended in the posterior thigh and passed through the intramuscular space caudal to the quadratus femoris. It then coursed anteriorly and joined the deep femoral vein. The femoral vein originated from the popliteal vein; it passed through the adductor canal, ascended in the femoral triangle, and passed under the inguinal ligament after receiving the deep femoral vein. On the right, the PSV ascended in the posterior thigh and passed through the intermuscular space between the adductor magnus and adductor minor (a lower position than on the left); it then coursed anteriorly and merged with the femoral vein. The right femoral vein originated from the popliteal vein; it then passed through the adductor canal, ascended in the femoral triangle, and merged with the PSV. It is important to correctly diagnose PSV at the time of surgical or radiological intervention to avoid complications of the procedure and to improve outcomes. PSV can cause unexpected bleeding during lower extremity surgery. Clinicians should be aware of this rare anomaly.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intersegmental Fixation with an Interspinous Spacer (IFIS) for Lumbar Spinal Instability: Surgical Technique and Clinical Outcomes. 棘间间隔器（IFIS）的节段间固定治疗腰椎不稳定：手术技术和临床结果。

Kurume Medical Journal Pub Date : 2025-04-18 DOI: 10.2739/kurumemedj.MS7134007

Kimiaki Sato, Kimiaki Yokosuka, Shinji Morito, Masafumi Goto, Suguto Futami, Yusuke Nishida, Kei Yamada, Koji Hiraoka

引用次数: 0

Discovery of Feeding Regulatory Peptides and The Importance of Peptide Discovery Research. 饲养调节肽的发现及肽发现研究的重要性。

Kurume Medical Journal Pub Date : 2025-04-18 DOI: 10.2739/kurumemedj.MS7134001

Takanori Ida, Kazuma Matsui, Sayaka Nagata, Tomoya Nakamachi, Yuki Shiimura, Takahiro Sato, Masayasu Kojima

引用次数: 0

Role of Computed Tomography Angiography in Arterio-Enteric Fistula Treatment. 计算机断层扫描血管造影术在动脉-动脉瘘治疗中的作用。

Kurume Medical Journal Pub Date : 2025-04-04 DOI: 10.2739/kurumemedj.MS7134002

Asako Kuhara, Masamichi Koganemaru, Masayuki Oka, Shuichi Tanoue, Toshi Abe

引用次数: 0