Kurume Medical Journal最新文献_第10页

Direct Oral Anticoagulants Would Be Best Choice for Atrial Fibrillation Patients After Coronary Stenting: Retrospective Study in a Japanese Population. 直接口服抗凝剂将是冠状动脉支架植入术后房颤患者的最佳选择:日本人群的回顾性研究

Kurume Medical Journal Pub Date : 2023-07-03 DOI: 10.2739/kurumemedj.MS682015

Hiroshi Koiwaya, Nozomi Watanabe, Nehiro Kuriyama, Yoshisato Shibata

{"title":"Direct Oral Anticoagulants Would Be Best Choice for Atrial Fibrillation Patients After Coronary Stenting: Retrospective Study in a Japanese Population.","authors":"Hiroshi Koiwaya, Nozomi Watanabe, Nehiro Kuriyama, Yoshisato Shibata","doi":"10.2739/kurumemedj.MS682015","DOIUrl":"https://doi.org/10.2739/kurumemedj.MS682015","url":null,"abstract":"Background: The combination of dual antiplatelet therapy (DAPT) plus warfarin in atrial fibrillation (AF) patients after coronary stenting has been reported to confer a significant risk of bleeding complications. Direct oral anticoagulants (DOAC) reduce the risk of stroke and bleeding complications in AF patients compared to warfarin. The optimal anticoagulation strategy for Japanese non-valvular AF patients after coronary stenting remains unclear.Methods: A total of 3230 patients who underwent coronary stenting were retrospectively reviewed. Of these, 284 cases (8.8%) were complicated by AF. Following coronary stenting, 222 patients received triple antithrombotic therapy (TAT) by DAPT plus oral anticoagulants; 121 patients received DAPT plus warfarin, and 101 patients received DAPT plus DOAC. We compared the clinical data between the two groups.Results: The median International normalized ratio (INR) in the DAPT plus warfarin group was 1.61. Bleeding complications occurred in both groups. No cerebral infarction occurred in the DAPT plus DOAC group, while 4.1% of the DAPT plus warfarin group experienced cerebral infarction during follow-up (P=0.04). Twelve-month freedom from cerebral infarction, myocardial infarction, and cardiovascular death was significantly higher in the DAPT plus DOAC group than in the DAPT plus warfarin group [100% vs. 93.4%, P=0.009].Conclusions: DOAC might be an optimal selection as an oral anticoagulant for Japanese AF patients who are receiving DAPT after PCI. A larger, longitudinal follow-up should be performed to clarify the clinical advantage of DOAC over warfarin, including among patients who receive single antiplatelet after coronary stent implantation.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":"68 2","pages":"97-106"},"PeriodicalIF":0.0,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9797853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endovascular Aortic Repair for Heavily Calcified Abdominal Aortic Stenosis Using the Gore Viabahn Vbx Balloon-Expandable Covered Stent. 使用Gore Viabahn vx球囊可膨胀覆膜支架修复严重钙化的腹主动脉狭窄。

Kurume Medical Journal Pub Date : 2023-07-03 DOI: 10.2739/kurumemedj.MS682014

Takanori Kono, Hiroyuki Otsuka, Tomoyuki Anegawa, Atsunobu Oryoji, Yusuke Shintani, Eiji Nakamura, Shinichi Hiromatsu, Eiki Tayama

引用次数: 0

Discontinuation of Intravenous Catecholamine by Oral Ivabradine in a Patient with Decompensated Heart Failure with Low Cardiac Output Syndrome. 低心输出量综合征失代偿性心力衰竭患者口服伊伐布雷定停用静脉儿茶酚胺

Kurume Medical Journal Pub Date : 2023-07-03 DOI: 10.2739/kurumemedj.MS682007

Ryo Shibata, Jinya Takahashi, Hiromi Sato, Munehisa Bekki, Kodai Shibao, Hideya Sato, Shoichiro Nohara, Akihiro Honda, Naoki Itaya, Hidetoshi Chibana, Yoshihiro Fukumoto

引用次数: 0

Correlation of Celiac Diseases with Candida Spp. Based on Anti-gliadin Antibodies. 基于抗麦胶蛋白抗体的乳糜泻与念珠菌的相关性

Kurume Medical Journal Pub Date : 2023-07-03 DOI: 10.2739/kurumemedj.MS682018

Ali Abdul Hussein S Al-Janabi, Maitham Jassim Mohammed

引用次数: 0

A Case of Urinary Extravasation and Urolithiasis During Pregnancy. 妊娠期尿外渗及尿石症1例。

Kurume Medical Journal Pub Date : 2023-04-04 DOI: 10.2739/kurumemedj.MS681006

Masato Ishimatsu, Toshiyuki Yoshizato, Yusuke Kurokawa, Kosuke Kawakami, Naofumi Okura

引用次数: 0

Impact of Interferon on the Prognosis of Hepatitis C Virus-Related Hepatocellular Carcinoma Patients with a Sustained Virological Response -An Additional Comparison Between Preoperative and Postoperative Sustained Virological Response. 干扰素对持续病毒学应答的丙型肝炎病毒相关肝细胞癌患者预后的影响——术前和术后持续病毒学应答的额外比较

Kurume Medical Journal Pub Date : 2023-04-04 DOI: 10.2739/kurumemedj.MS681001

Daisuke Muroya, Taro Nishimura, Hiroki Kanno, Satoki Kojima, Shogo Fukutomi, Masanori Akashi, Yoriko Nomura, Yuichi Goto, Toshihiro Sato, Hisamune Sakai, Toru Hisaka, Yoshito Akagi, Koji Okuda

{"title":"Impact of Interferon on the Prognosis of Hepatitis C Virus-Related Hepatocellular Carcinoma Patients with a Sustained Virological Response -An Additional Comparison Between Preoperative and Postoperative Sustained Virological Response.","authors":"Daisuke Muroya, Taro Nishimura, Hiroki Kanno, Satoki Kojima, Shogo Fukutomi, Masanori Akashi, Yoriko Nomura, Yuichi Goto, Toshihiro Sato, Hisamune Sakai, Toru Hisaka, Yoshito Akagi, Koji Okuda","doi":"10.2739/kurumemedj.MS681001","DOIUrl":"https://doi.org/10.2739/kurumemedj.MS681001","url":null,"abstract":"Background: Several studies have reported that interferon (IFN) therapy improves the prognosis of patients with hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), especially for patients who have achieved a sustained virological response (SVR). We retrospectively evaluated the clinicopathological outcomes of patients who acquired an SVR through IFN therapy pre- or post-hepatectomy for treatment naïve HCC.Method: Among the 305 HCV-related HCC patients entered in this study, 59 patients (SVR group) achieved an SVR after IFN therapy and received hepatectomy either after or before achieving an SVR (n=36 and n=23, respectively), while the remaining 179 patients (control group) did not receive IFN therapy, or did not achieve an SVR through IFN therapy (n=67).Results: In the SVR group, the overall survival (OS) and disease-free survival (DFS) rates were significantly higher than in the control group. We evaluated the prognosis of patients with an SVR achieved pre- or post-hepatectomy separately. There were no significant differences in OS and DFS.Conclusion: This result suggests that the prognosis of naïve HCC may be improved by additional INF therapy to achieve SVR status after hepatectomy.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":"68 1","pages":"9-18"},"PeriodicalIF":0.0,"publicationDate":"2023-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9255628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute Mitral Regurgitation After Blunt Chest Trauma: A Case Report. 钝性胸外伤后急性二尖瓣返流1例报告。

Kurume Medical Journal Pub Date : 2023-04-04 DOI: 10.2739/kurumemedj.MS681002

Shigeaki Aoyagi, Satoru Tobinaga, Kumiko Wada, Shin-Ichi Nata, Hiroshi Yasunaga

{"title":"Acute Mitral Regurgitation After Blunt Chest Trauma: A Case Report.","authors":"Shigeaki Aoyagi, Satoru Tobinaga, Kumiko Wada, Shin-Ichi Nata, Hiroshi Yasunaga","doi":"10.2739/kurumemedj.MS681002","DOIUrl":"https://doi.org/10.2739/kurumemedj.MS681002","url":null,"abstract":"Myocardial contusion is the most common cardiac injury from blunt chest trauma (BCT), whereas isolated valve injury is uncommon. We report a case of acute mitral regurgitation (MR) due to isolated valve injury after BCT. A 60-year-old man received an impact on his left chest by a car wheel three weeks prior to visiting our hospital. At the time a diagnosis of contusion of the chest wall without rib and sternal fractures was made. Thereafter, the patient had progressive worsening of heart failure symptoms. Eventually he developed dyspnea on slight exertion but echocardiographic evaluation was not performed at the time of diagnosis or during the three weeks prior to admission. At admission a holosystolic murmur was heard. Transthoracic echocardiography revealed prolapse of the posterior mitral leaflet due to torn chordae tendineae with severe MR and normal left ventricular wall motion. At surgery, torn chordae tendineae and a leaflet tear of the posterior leaflet were detected, and mitral valve repair was achieved without residual MR. Pathological examination of the torn chordae showed no findings of endocarditis or myxomatous degeneration. Echocardiography may play an important role for accurate and prompt diagnosis of cardiac lesions in patients with recent or a history of high-energy BCT.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":"68 1","pages":"39-42"},"PeriodicalIF":0.0,"publicationDate":"2023-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9255627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of the Gerdq Questionnaire for Diagnosing Gastroesophageal Reflux Disease After Esophagectomy for Esophageal Cancer. Gerdq问卷对食管癌术后胃食管反流病的诊断价值

Kurume Medical Journal Pub Date : 2023-04-04 DOI: 10.2739/kurumemedj.MS681004

Kohei Saisho, Naoki Mori, Toshiaki Tanaka, Satoru Matono, Haruhiro Hino, Kazutaka Kadoya, Ryosuke Nishida, Masahiro Fujisaki, Masashi Nakagawa, Fumihiko Fujita, Masahiro Fujii, Takashi Yanagawa, Masahiro Mitsuoka, Yoshito Akagi

{"title":"Effectiveness of the Gerdq Questionnaire for Diagnosing Gastroesophageal Reflux Disease After Esophagectomy for Esophageal Cancer.","authors":"Kohei Saisho, Naoki Mori, Toshiaki Tanaka, Satoru Matono, Haruhiro Hino, Kazutaka Kadoya, Ryosuke Nishida, Masahiro Fujisaki, Masashi Nakagawa, Fumihiko Fujita, Masahiro Fujii, Takashi Yanagawa, Masahiro Mitsuoka, Yoshito Akagi","doi":"10.2739/kurumemedj.MS681004","DOIUrl":"https://doi.org/10.2739/kurumemedj.MS681004","url":null,"abstract":"Background: Gastroesophageal reflux disease (GERD) is a common complication after esophagectomy with gastric tube reconstruction. The GerdQ questionnaire was developed for diagnosing GERD in primary care patients. Its effectiveness in patients after esophagectomy remains unknown. In this study, we evaluated the usefulness of the GerdQ questionnaire for diagnosing GERD after esophagectomy for esophageal cancer.Materials and methods: A total of 124 patients with esophageal cancer underwent right transthoracic esophagectomy with gastric tube reconstruction between January 2010 and December 2016. Esophagogastroduodenoscopy and 24-hour esophageal pH-metry were performed at 1 month, 1 year, and 2 years postoperatively. The GerdQ questionnaire was administered at the same postoperative time points. We assessed any correlation between the GerdQ scores and the endoscopy and pH-metry findings.Results: The incidence rates of GERD at 1 month, 1 year and 2 years post-surgery were 31.6%, 46.9%, and 49.2%, respectively. The GerdQ questionnaire showed 77% sensitivity and 56% specificity for diagnosing GERD at 2 years after esophagectomy when the cutoff point was 7. However, the optimal cutoff points were different at each postoperative time, and the scores showed some imbalance between sensitivity and specificity. Regurgitation may be a useful indicator, as the frequency of regurgitation was significantly higher in patients with GERD than in patients without GERD at 1 year (P = 0.046) and 2 years postoperatively (P = 0.048).Conclusion: The GerdQ questionnaire is not a useful diagnostic tool for GERD in patients who have undergone esophagectomy for esophageal cancer.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":"68 1","pages":"25-31"},"PeriodicalIF":0.0,"publicationDate":"2023-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9255625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Kurume Medical Journal Pub Date : 2023-04-04 DOI: 10.2739/kurumemedj.MS681005

Yusuke Kurokawa, Toshiyuki Yoshizato, Hitoshi Obara, Takuya Shimomura, Yutaka Kozuma, Tatsuyuki Kakuma, Daizo Hori, Kimio Ushijima

{"title":"Related Factors for Abnormal Umbilical Cord Insertion: A Preliminary Study Based on Two Regional Tertiary Hospitals in Japan.","authors":"Yusuke Kurokawa, Toshiyuki Yoshizato, Hitoshi Obara, Takuya Shimomura, Yutaka Kozuma, Tatsuyuki Kakuma, Daizo Hori, Kimio Ushijima","doi":"10.2739/kurumemedj.MS681005","DOIUrl":"https://doi.org/10.2739/kurumemedj.MS681005","url":null,"abstract":"Objective: We elucidated maternal background, perinatal complications and outcomes as potential related factors for abnormal umbilical cord insertion (ACI) -velamentous and marginal- based on data from two tertiary perinatal hospitals in Japan.Materials and methods: The subjects were 3,741 women with singleton pregnancies who delivered at ≥ 22 weeks' gestation in Kurume University Hospital and St. Mary's Hospital, Kurume, Japan from January 2013 to December 2015. They were divided into two groups, with and without ACI. Related factors were extracted from the medical registry database of the perinatal committee in the Japan Society of Obstetrics and Gynecology. Random Forest and stepwise logistic regression models were employed to evaluate their impact on ACI.Results: Related factors for ACI in terms of maternal background and perinatal complications and outcomes were: pre-pregnancy smoking habit (adjusted odds ratio, OR, 3.38; 95% confidence interval, CI, 2.20-5.20; P < 0.0001); conception using assisted reproductive technology (adjusted OR, 2.00; 95% CI, 1.11-3.60; P = 0.021); placenta previa (adjusted OR, 4.74; 95% CI, 2.06-10.90; P < 0.0001); fetal growth restriction (adjusted OR, 2.43; 95% CI, 1.49-3.97; P < 0.0001); and non-reassuring fetal status during labor (adjusted OR, 2.74; 95% CI, 1.71-4.38; P < 0.0001).Conclusion: This was a preliminary study attempting to elucidate related factors for ACI in a Japanese population. However, further large-scale studies are needed in Japan.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":"68 1","pages":"19-23"},"PeriodicalIF":0.0,"publicationDate":"2023-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9255626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patient-Specific Femoral Guide with 3-Dimensional Support Software in Anterolateral Supine Approach of Total Hip Arthroplasty: A Single-Arm Trial. 在全髋关节置换术的仰卧前外侧入路中，带三维支持软件的患者专用股骨导向器:单臂试验。

Kurume Medical Journal Pub Date : 2023-04-04 DOI: 10.2739/kurumemedj.MS681003

Daihei Kida, Hiroya Hashimoto, Noriko Ito, Yukari Kito, Kouichi Mori, Yosuke Hattori, Nobunori Takahashi, Masaaki Matsubara

{"title":"Patient-Specific Femoral Guide with 3-Dimensional Support Software in Anterolateral Supine Approach of Total Hip Arthroplasty: A Single-Arm Trial.","authors":"Daihei Kida, Hiroya Hashimoto, Noriko Ito, Yukari Kito, Kouichi Mori, Yosuke Hattori, Nobunori Takahashi, Masaaki Matsubara","doi":"10.2739/kurumemedj.MS681003","DOIUrl":"https://doi.org/10.2739/kurumemedj.MS681003","url":null,"abstract":"Currently, there is no surgical assistance system that can perform a three-dimensional (3D) planned total hip arthroplasty (THA) by methods other than surgical assistance navigation or robots. However, they are expensive, cumbersome, and subject to additional invasiveness, so there is a need for a simpler and less expensive 3D surgical support system. In this study, THA was performed using the anterolateral approach (Watson-Jones) in the supine position in 23 subjects to examine the efficacy and safety of a patient-specific femoral guide linked to 3D surgery support software. In 48% of the subjects, the difference in anterior torsion angle from the preoperative plan was within ±5 degrees, while in 83% of the subjects, the difference was within ±10 degrees. The 95% confidence interval (4.61-8.70) of the absolute difference did not fall below the pre-defined threshold of 7.2 degrees (p = 0.293). No adverse events were observed other than 2 cases (8.7%) of hemorrhage that required a blood transfusion. We confirmed the efficacy and safety of the patient-specific femoral guide in anterolateral supine approach THA.","PeriodicalId":39559,"journal":{"name":"Kurume Medical Journal","volume":"68 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2023-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9255629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0