Polski Merkuriusz Lekarski最新文献

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Enterosorption therapy of chronic obstructive pulmonary disease against the background of endogenous intoxication. 内源性中毒背景下慢性阻塞性肺疾病的肠吸收治疗。
Polski Merkuriusz Lekarski Pub Date : 2026-01-01 DOI: 10.36740/Merkur202602108
Larysa Ya Fedoniuk, Svitlana V Kucher, Olena V Lototska
{"title":"Enterosorption therapy of chronic obstructive pulmonary disease against the background of endogenous intoxication.","authors":"Larysa Ya Fedoniuk, Svitlana V Kucher, Olena V Lototska","doi":"10.36740/Merkur202602108","DOIUrl":"10.36740/Merkur202602108","url":null,"abstract":"<p><strong>Objective: </strong>Aim: improve the effectiveness of treatment for patients with COPD in the acute phase with clinical and laboratory manifestations of endogenous intoxication by including carbon or organosilicon sorbents in complex therapy.</p><p><strong>Patients and methods: </strong>Materials and Methods: To evaluate the effectiveness of enterosorption therapy in the complex treatment of patients with COPD in the acute phase with clinical and laboratory manifestations of endogenous intoxication, patients were divided into three groups according to severity. The first group consisted of 34 patients (21.9%) with mild bronchial obstruction (GOLD 1), the second group included 64 patients (41.3%) with moderate bronchial obstruction (GOLD 2), and the third group included 57 patients (36.8%) with severe bronchial obstruction (GOLD 3). The control group consisted of 20 healthy people aged 40 to 78 years. The following exclusion criteria were used: the presence of diabetes mellitus, acute coronary syndrome, previous myocardial infarction, rheumatological pathology, oncological and infectious diseases, acute inflammatory processes of any localization in patients.</p><p><strong>Results: </strong>Results: COPD in the exacerbation phase is accompanied by clinical and laboratory manifestations of endotoxicosis, more pronounced in patients with severe broncho-obstruction. This is manifested by an increase in the content of endogenous intoxication indicators in blood serum (molecules of medium weight by 84% and 126% (p<0.001) and erythrocyte intoxication index by 86% (p<0.001)). There is a direct correlation of mean strength between the severity of the disease and the level of MSM254 and MSM280 (r=0.496 and r=0.557, p<0.01) and weak strength - with an erythrocyte index of intoxication (r=0.253, p<0.01). COPD in the exacerbation phase is accompanied by the activation of free radical processes, most pronounced in patients with severe broncho-obstruction, manifested by a probable increase in malondialdehyde - by 116% (p<0.001) and a decrease in the activity of superoxide dismutase - by 59% (p<0.01) compared to the control. There is a direct mean strength correlation between severity and malondialdehyde levels (r=0.486, p<0.01) and inverse with serum superoxide dismutase (r=-0.500, p<0.01). MDA content in blood serum increases, SOD activity decreases with increasing age of patients.</p><p><strong>Conclusion: </strong>Conclusions: COPD exacerbation accompanied by clinical and laboratory manifestations of endogenous intoxication, namely increasing concentrations of malondialdehyde and superoxide dismutase activity decrease depending on the severity and age of bronchial patients. With the progression of the disease also increases the content of interleukin 1β and 10, tumor necrosis factor α, circulating immune complexes, immunoglobulin E and reduced lysozyme activity in serum, in proportion to the increase in the severity of the disease. The use in treat","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"54 2","pages":"151-157"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147784219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fibromuscular dysplasia as a rare cause of ischaemic stroke - a case report. 纤维肌肉发育不良是缺血性中风的罕见病因- 1例报告。
Polski Merkuriusz Lekarski Pub Date : 2026-01-01 DOI: 10.36740/Merkur202602120
Krystian Kansik, Jakub Sadowski, Julia Pawłowska, Małgorzata Otwinowska, Mateusz Roszak, Beata Łabuz-Roszak
{"title":"Fibromuscular dysplasia as a rare cause of ischaemic stroke - a case report.","authors":"Krystian Kansik, Jakub Sadowski, Julia Pawłowska, Małgorzata Otwinowska, Mateusz Roszak, Beata Łabuz-Roszak","doi":"10.36740/Merkur202602120","DOIUrl":"10.36740/Merkur202602120","url":null,"abstract":"<p><p>Fibromuscular dysplasia (FMD) is a rare cause of ischemic stroke. It is an important element of differential diagnosis that should be considered, especially in patients who do not have common cardiovascular risk factors. A 65-year-old man was admitted with transient left arm weakness and drooping of the mouth, asting about 3 minutes, followed by left-sided paresthesia. A similar episode had occurred a week earlier. On admission, the patient was alert and oriented. Neurological exam showed subtle flattening of the left nasolabial fold and a tendency to a positive ipsilateral Babinski sign, with no other abnormalities. Brain MRI revealed a subacute ischemic lesion in the anterior deep structures and a hyperacute focus at the right temporo-occipital border. CT angiography showed bilateral internal carotid artery changes suggestive of FMD, critical stenosis of the right MCA (M1), and aneurysmal dilation of the left ophthalmic artery origin. Digital subtraction angiography (DSA) confirmed a wide-neck saccular aneurysm of the left internal carotid artery (ICA). Rehabilitation and multidisciplinary consultations were undertaken. The patient was discharged in good condition without significant neurological deficits. Regular blood pressure control, atherosclerotic diet, physical activation and taking medications (antihypertensive drugs, acetylsalicylic acid and statin) regularly were recommended. Due to the diagnosis of a saccular aneurysm of the left ICA, a referral was issued to the neurosurgery department. The described case illustrates the need for a comprehensive and interdisciplinary approach to a patient with stroke in order to determine the etiology of the stroke and implement secondary prevention.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"54 2","pages":"236-240"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147784300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Features of cerebral blood flow in patients with dyscirculatory encephalopathy and concomitant hypothyroidism at long-term follow-up. 长期随访循环障碍性脑病伴甲状腺功能减退患者的脑血流特征。
Polski Merkuriusz Lekarski Pub Date : 2026-01-01 DOI: 10.36740/Merkur202603102
Olena V Lytvyn, Olha Y Kovalenko, Kyrylo O Mikhaliev
{"title":"Features of cerebral blood flow in patients with dyscirculatory encephalopathy and concomitant hypothyroidism at long-term follow-up.","authors":"Olena V Lytvyn, Olha Y Kovalenko, Kyrylo O Mikhaliev","doi":"10.36740/Merkur202603102","DOIUrl":"https://doi.org/10.36740/Merkur202603102","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To evaluate cerebral blood flow characteristics in patients with dyscirculatory encephalopathy (DE) and concomitant hypothyroidism in the long-term follow-up period.</p><p><strong>Patients and methods: </strong>Materials and Methods: A single-center cohort study consecutively included 60 patients with hypertensive DE and concomitant hypothyroidism (mean age 61±6 years; 95% women). In the long-term follow-up period (mean duration - 10 years), results of repeated clinical-neurological and instrumental examinations of 52 patients were analysed. Duplex scanning of extra- and intracranial vessels assessed peak systolic velocity (Vps) and end-diastolic velocity (Ved), and resistive index (RI) and pulsatility index (PI) were calculated.</p><p><strong>Results: </strong>Results: At baseline, patients with DE and concomitant hypothyroidism predominantly presented with cephalgic (67.3%), vestibular (61.5%), and cerebroasthenic (63.5%) syndromes. In the long-term follow-up period, an increase in the frequency of vestibular syndrome was observed, reaching 80.8% (p=0.034). Duplex scanning demonstrated an increase in Vps in the left common carotid artery (CCA) and bilateral internal carotid arteries (ICA), accompanied by a decrease in Ved in the middle cerebral artery (MCA) on both sides. Additionally, an increase in RI was observed in the right CCA and left MCA. At the same time, in the vertebrobasilar system, a decrease in flow velocity parameters was noted in the right vertebral artery (V4 segment) and basilar artery (BA), along with an increased RI in the right V4 segment of the vertebral artery.</p><p><strong>Conclusion: </strong>Conclusions: Long-term follow-up demonstrated an increased frequency of vestibular syndrome, deterioration of cerebral blood flow predominantly in the carotid circulation due to reduced vascular elasticity, and decreased flow velocity in the vertebrobasilar system in patients with DE and concomitant hypothyroidism. These findings justify the need for timely diagnosis and correction of thyroid dysfunction in patients with chronic cerebral ischemia to optimize therapeutic, preventive, and rehabilitation strategies.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"54 3","pages":"245-250"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148425353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peculiarities of security-sector specialists' psychological adaptation to stressful conditions of professional activities. 安全部门专家对专业活动压力条件的心理适应特点。
Polski Merkuriusz Lekarski Pub Date : 2026-01-01 DOI: 10.36740/Merkur202603108
Olena G Babchuk, Olha M Pasko, Tetyana V Matiienko, Natalia T Zhuk, Zoia A Dmytruk, Inha A Serednytska, Ivan M Okhrimenko
{"title":"Peculiarities of security-sector specialists' psychological adaptation to stressful conditions of professional activities.","authors":"Olena G Babchuk, Olha M Pasko, Tetyana V Matiienko, Natalia T Zhuk, Zoia A Dmytruk, Inha A Serednytska, Ivan M Okhrimenko","doi":"10.36740/Merkur202603108","DOIUrl":"https://doi.org/10.36740/Merkur202603108","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To investigate indicators of psychological adaptation among security-sector specialists to the stressful conditions of professional activities during wartime.</p><p><strong>Patients and methods: </strong>Materials and Methods: The research, which lasted from 2023 to 2025, involved 120 male security-sector specialists: experimental group (EG, n=60) - specialists who performed their service duties in combat conditions; control group (CG, n=60) - specialists whose activities took place in conditions of relative safety. Research methods: theoretical analysis and generalization of literature, psychological methods, and statistical methods.</p><p><strong>Results: </strong>Results: A significantly higher level of both reactive (by 7.06 points; p<0.01) and personal (by 4.29 points; p<0.05) anxiety has been found in the CG specialists compared to the EG. It has been found that specialists in the EG, compared to the CG, demonstrated significantly worse indicators of satisfaction: with themselves, their mental state - by 7.32 points; the situation and its dynamics - by 6.19 points; the sphere of interpersonal relationships - by 2.37 points; their functional state - by 2.47 points; their life-sustaining activities in general - by 7.23 points.</p><p><strong>Conclusion: </strong>Conclusions: It has been proven that unfavorable factors of combat conditions and excessive physical and mental stress in wartime lead to a gradual loss of satisfaction with life-sustaining activities, an increased risk of developing stress disorders accompanied by symptoms of avoidance, distress, exhaustion, and reexperiencing trauma. The intensity and excessiveness of psycho-traumatic influences, the inability to form psychological defense mechanisms, and the severity of psychosomatic components of the stress response significantly alter the adaptive capabilities of security-sector specialists.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"54 3","pages":"293-299"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148425391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modern technological innovations in the management of Prader-Willi syndrome: From restrictive supervision to digital autonomy. 普瑞德-威利综合征管理中的现代技术创新:从限制性监督到数字自治。
Polski Merkuriusz Lekarski Pub Date : 2026-01-01 DOI: 10.36740/Merkur202603116
Iga Maria Owczarek-Danowska, Agnieszka Wiktoria Paluszek, Filip Jasiński, Magdalena Bieniak, Maja Kubiaczyk, Maria Mamczak, Martyna Michalik
{"title":"Modern technological innovations in the management of Prader-Willi syndrome: From restrictive supervision to digital autonomy.","authors":"Iga Maria Owczarek-Danowska, Agnieszka Wiktoria Paluszek, Filip Jasiński, Magdalena Bieniak, Maja Kubiaczyk, Maria Mamczak, Martyna Michalik","doi":"10.36740/Merkur202603116","DOIUrl":"10.36740/Merkur202603116","url":null,"abstract":"<p><strong>Objective: </strong>Aim: The study evaluates the effectiveness of wearable biometric devices, geofencing systems, and artificial intelligence algorithms in improving the quality of life and autonomy of individuals with Prader-Willi syndrome. It analyses the impact of digital ecosystems on reducing caregiver burden and personalizing therapy through objective data analysis.</p><p><strong>Patients and methods: </strong>Materials and Methods: A systematic literature review was conducted in PubMed, Web of Science, and the Cochrane Library databases since 2019. Research focused on metabolic monitoring, the use of gamification and virtual reality in rehabilitation, and the implementation of smart home technologies for patients with rare genetic syndromes. Analysis indicates that data from wearable devices enables the detection of prodromal states, mitigating episodes of hyperphagia and aggression. Geofencing systems provide a safe environment for autonomous physical activity, improving cardiovascular fitness and reducing caregiver anxiety. Artificial intelligence algorithms, by personalizing the energy balance with a precision of 10 kilocalories, significantly optimize weight reduction.</p><p><strong>Conclusion: </strong>Conclusions: The digital support ecosystem redefines the care paradigm for Prader-Willi syndrome. Replacing human supervision with autonomous algorithmic control promotes behavioural stabilization and allows for greater patient self-determination. This process increases biological safety and significantly reduces the burden on caregivers, forming the basis of modern, individualized therapy.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"54 3","pages":"362-367"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148425327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structural remodeling of the glomerular filtration barrier and renal tubular structures during experimental alcohol intoxication. 实验性酒精中毒期间肾小球滤过屏障和肾小管结构的结构重塑
Polski Merkuriusz Lekarski Pub Date : 2026-01-01 DOI: 10.36740/Merkur202604117
Vasyl M Ivanochko, Andrii O Yurakh, Iryna M Ananevych, Oksana H Popadynets, Liliia V Sobol, Larysa Ya Fedoniuk
{"title":"Structural remodeling of the glomerular filtration barrier and renal tubular structures during experimental alcohol intoxication.","authors":"Vasyl M Ivanochko, Andrii O Yurakh, Iryna M Ananevych, Oksana H Popadynets, Liliia V Sobol, Larysa Ya Fedoniuk","doi":"10.36740/Merkur202604117","DOIUrl":"https://doi.org/10.36740/Merkur202604117","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To study changes in the structural components of the glomerular filtration barrier and renal tubular structures following exposure to alcoholic beverages of varying strength and quality in an experimental model.</p><p><strong>Patients and methods: </strong>Materials and Methods: This experimental study was conducted on 130 sexually mature male Wistar albino rats. The animals were divided into four experimental groups of 30 each, according to the type of alcoholic beverage administered: vodka (40% alcohol by volume, ABV), home-distilled spirits (40% and 50% ABV), and wine (17% ABV). Each group was further subdivided into three subgroups of 10 animals according to the first (5 days), second (9 days), and third (12 days) stages of alcohol administration. Ten animals served as controls. All procedures involving animals were performed in accordance with bioethical standards. Morphological analysis was carried out using histological, electron microscopic, and morphometric methods.</p><p><strong>Results: </strong>Results: Administration of 40% ABV vodka, 40% ABV home-distilled spirits, and 17% ABV wine for 5 days did not induce noticeable morphological changes in the components of the glomerular filtration barrier or renal tubular structures. At this stage, administration of 50% ABV home-distilled spirits induced functional stress. On day 9, administration of 40% ABV vodka and 17% ABV wine resulted in hypertrophy and hyperplasia of both the components of the glomerular filtration barrier and renal tubular structures. Administration of 40% ABV home-distilled spirits during this period induced initial signs of destruction. Administration of 50% ABV home-distilled spirits over the same period led to an overload of adaptive and protective mechanisms. By day 12, administration of 40% ABV and 50% ABV home-distilled spirits caused pronounced destructive changes, whereas 40% ABV vodka and 17% ABV wine induced functional stress.</p><p><strong>Conclusion: </strong>Conclusions: The most pronounced destructive changes in the components of the glomerular filtration barrier and renal tubular structures were observed in animals administered 50% ABV home-distilled spirits, whereas the least pronounced changes were associated with 17% ABV fortified wine. The severity of destructive changes progressively increased with the duration of alcohol administration. Keyword s:, , , ,.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"54 4","pages":"500-507"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148945885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adaptive swimming as a means of physical and sports rehabilitation for people with musculoskeletal disorders. 适应性游泳作为肌肉骨骼疾病患者身体和运动康复的一种手段。
Polski Merkuriusz Lekarski Pub Date : 2026-01-01 DOI: 10.36740/Merkur202602110
Kostiantyn V Prontenko, Valentyn V Bondarenko, Anton M Chernikov, Oleksandr A Tomenko, Halyna D Kondratska, Olha H Bashtova, Valerii O Gavryliuk
{"title":"Adaptive swimming as a means of physical and sports rehabilitation for people with musculoskeletal disorders.","authors":"Kostiantyn V Prontenko, Valentyn V Bondarenko, Anton M Chernikov, Oleksandr A Tomenko, Halyna D Kondratska, Olha H Bashtova, Valerii O Gavryliuk","doi":"10.36740/Merkur202602110","DOIUrl":"10.36740/Merkur202602110","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To investigate the impact of adaptive swimming training sessions on the psycho-emotional and functional state of individuals with musculoskeletal disorders.</p><p><strong>Patients and methods: </strong>Materials and Methods: The research was conducted in 2025, with 32 male service members aged 26-58 who underwent rehabilitation for musculoskeletal injuries over 6 weeks. The research used a combination of theoretical, empirical, and mathematical statistical methods. The psycho-emotional state was assessed using the Wessman-Ricks technique, and the functional state was assessed using a 100 m swimming test and the duration of heart rate recovery after exercise.</p><p><strong>Results: </strong>Results: Data analysis showed that adaptive swimming training sessions have a pronounced rehabilitative effect: they normalize the psycho-emotional state, reduce stress levels, and increase the body's adaptive capabilities. The integral indicator of emotional state after 6 weeks of training increased by 1.15 points (p≤0.001) and reached a good level, reflecting the restoration of emotional balance. Functional indicators also improved: the time to cover a distance of 100 meters was reduced by 51 seconds (p≤0.001); the duration of heart rate recovery was reduced by 3.65 beats per minute (p≤0.001).</p><p><strong>Conclusion: </strong>Conclusions: It has been established that adaptive swimming training sessions contribute to improving the psycho-emotional state and functional capabilities of individuals with musculoskeletal disorders. A significant improvement in the integral indicators of the cardiovascular system's emotional and functional states has been observed.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"54 2","pages":"163-168"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147784374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative effects of intravenous furosemide and torsemide on survival and length of hospital stay in acute heart failure. 静脉滴注速尿和托塞米对急性心力衰竭患者生存和住院时间的影响。
Polski Merkuriusz Lekarski Pub Date : 2026-01-01 DOI: 10.36740/Merkur202602103
Małgorzata Małek-Elikowska, Andrzej Szyszka, Julita Fedorowicz, Cyntia Szymańska-Łyczkowska, Rafał Dankowski, Artur Baszko
{"title":"Comparative effects of intravenous furosemide and torsemide on survival and length of hospital stay in acute heart failure.","authors":"Małgorzata Małek-Elikowska, Andrzej Szyszka, Julita Fedorowicz, Cyntia Szymańska-Łyczkowska, Rafał Dankowski, Artur Baszko","doi":"10.36740/Merkur202602103","DOIUrl":"10.36740/Merkur202602103","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To investigate the impact of the initial choice between intravenous furosemide and torsemide on mortality outcomes and duration of hospital stay.</p><p><strong>Patients and methods: </strong>Materials and Methods: The prospective, open-label, comparative study included 68 adult patients hospitalized with acute heart failure (AHF). Furosemide was administered to 35 patients (51.5%) and torsemide to 33 patients (48.5%) during the first 48 hours after admission. Diuretic dosing was titrated according to urinary sodium concentration. After the initial 48 hours, further diuretic therapy was administered at the discretion of the attending physician. The primary endpoint was all-cause mortality, and the secondary endpoints were length of hospital stay and in-hospital mortality.</p><p><strong>Results: </strong>Results: All-cause mortality was 51.4% in patients treated with furosemide and 42.4% in those treated with torsemide (p=0.478). The median survival time was 633 days (95% CI 178-1,259) in the furosemide group and 1,093 days (95% CI 541-1,239) in the torsemide group, with no statistically significant difference in survival between the two treatment groups (p=0.44). No in-hospital deaths occurred in the torsemide group, whereas four in-hospital deaths (11.4%) were observed in the furosemide group (p=0.115). The mean length of hospital stay was 12±7 days in both groups (p=0.551).</p><p><strong>Conclusion: </strong>Conclusions: Both furosemide and torsemide showed no statistically significant differences in all-cause mortality, in-hospital mortality, and length of hospital stay.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"54 2","pages":"105-112"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147784394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resilience as a factor of psychological stability of modern police officers in crisis situations of their professional activities. 弹性作为现代警察在职业活动危机情境中的心理稳定因素。
Polski Merkuriusz Lekarski Pub Date : 2026-01-01 DOI: 10.36740/Merkur202602116
Olena O Yevdokimova, Serhii S Boichuk, Yana S Ponomarenko, Alla A Shylina, Viktoriia A Pavlovska-Kravchuk, Olena M Mokhorieva, Ivan M Okhrimenko
{"title":"Resilience as a factor of psychological stability of modern police officers in crisis situations of their professional activities.","authors":"Olena O Yevdokimova, Serhii S Boichuk, Yana S Ponomarenko, Alla A Shylina, Viktoriia A Pavlovska-Kravchuk, Olena M Mokhorieva, Ivan M Okhrimenko","doi":"10.36740/Merkur202602116","DOIUrl":"10.36740/Merkur202602116","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To investigate the psychological characteristics of resilience among modern police officers in wartime crises.</p><p><strong>Patients and methods: </strong>Materials and Methods: The research, which lasted from 2023 to 2025, involved 120 employees of the National Police of Ukraine: experimental group (EG, n=60) - police officers performing their duties in combat conditions; control group (CG, n=60) - police officers whose activities took place in relatively safe conditions. The resilience of police officers was assessed using three methods: the Connor-Davidson Resilience Scale, the Wagnild and Young Resilience Scale, and the Posttraumatic Growth Inventory.</p><p><strong>Results: </strong>Results: It has been established that resilience in police officers not only provides a basic ability to cope with the negative consequences of traumatic experiences, but also acts as a mechanism that helps transform these experiences into a source of development. It has been determined that police officers' resilience in combat conditions serves a protective function, helping maintain stability and minimize the destructive effects of stress. Overcoming extreme situations in such an environment contributes to rethinking life values, the formation of new meanings, and spiritual growth, thereby enhancing the ability to adapt.</p><p><strong>Conclusion: </strong>Conclusions: It has been shown that, under relatively safe conditions, resilience contributes to the internal restructuring of a police officer's personality and promotes personal growth. However, in combat situations, it tends to become a resourcee for preservation, minimizing the impact of traumatic events but not stimulating development through posttraumatic growth. This underscores the need for a comprehensive approach to developing resilience among police officers, whose work involves high levels of danger and psychological stress.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"54 2","pages":"205-212"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147784548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Academic performance and preclinical skills in the dental students of Ukrainian University. 乌克兰大学牙科专业学生的学习成绩和临床前技能。
Polski Merkuriusz Lekarski Pub Date : 2026-01-01 DOI: 10.36740/Merkur202601106
Lyudmyla Kaskova, Nataliia V Yanko, Irena Vashchenko, Marina Sadovski, Svitlana Novikova, Natalia Morhun
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