Polski Merkuriusz Lekarski最新文献

{"title":"Causes and management of Pica disorder among central Iraqi peoples.","authors":"Mohammed Rasool, Mahmood Jawad, Shathel Khalaf Noman, Mohammed Ejerish","doi":"10.36740/Merkur202402112","DOIUrl":"10.36740/Merkur202402112","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To find the causes and factors behind the Pica disorder, which helps in early diagnosis and appropriate treatments..</p><p><strong>Patients and methods: </strong>Materials and Methods: A retrospective cross-section study was carried out between July 1, 2022, and April 20, 2023, enrolling 300 patients from different provinces of central and south Iraq with Pica disease whose diagnosis depended on specialized physicians according to WHO guidelines. The participants were following up for three to six months in private clinics.</p><p><strong>Results: </strong>Results: 92.4% of the patients were female, and 41% of patients were under 20 years old, with low ferritin, HB, and vitamin D levels (80% of cases), and these markers showed a negative correlation with the number of Pica. Chowing of ice and clay were the common types of Pica, which represent about 30% each, while 34% of cases had multiple types, which had signs and symptoms of fever, palpitation, vomiting, abdominal pain, paleness, headaches, and hair loss. Six-month flows were better than three months.</p><p><strong>Conclusion: </strong>Conclusions: Pica was a disorder that could lead to behavior and emotional abnormalities that caused the patients to eat some things that were eaten by healthy people. This may be, as concluded from our results, due to reduced levels of ferritin, hemoglobin (Hb), and vitamin D that caused these psychological problems.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 2","pages":"226-232"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peculiarities of physical therapy of chronic obstructive pulmonary disease: practical experience.","authors":"Valeriy O Zhamardiy, Liudmyla V Kletsenko, Yevheniia V Vyshar, Sergii V Harkusha, Viktoriia Donchenko, Oksana V Hordiienko, Vadym B Voronetskyi","doi":"10.36740/Merkur202403105","DOIUrl":"https://doi.org/10.36740/Merkur202403105","url":null,"abstract":"<p><strong>Objective: </strong>Aim: The aim of the study is todetermine the feasibility of using a home pulmonary rehabilitation program and evaluate its impact on patients with COPD in the GOLD B group.</p><p><strong>Patients and methods: </strong>Materials and Methods: The study was conducted on the basis of the «Healthy Movements» studio (Poltava). Patients were involved in the study after receiving secondary (specialized) medical care, the basis of which was physical therapy treatment and exercise therapy in accordance with the clinical protocol approved by the internal order of the health care institution. A total of 30 people (aged 59 to 68.4 years) with II degree chronic obstructive pulmonary disease (50 % ≤ FEV1 < 80 % of normal) in remission took part in the study. Research methods: pedagogical, medical and biological , methods of mathematical statistics.</p><p><strong>Results: </strong>Results: Each patient confirmed the achievement of the general goal, namely, increasing the number of therapeutic exercises from 3 to 5 times a week, improving the quality of life, more active participation in improving their health and awareness of the disease. The patients considered self-management training to be the most valuable.</p><p><strong>Conclusion: </strong>Conclusions: Pulmonary rehabilitation is indicated for all patients, regardless of the degree of the disease. The most ef f ective are 6-12 week programs that include breathing exercises, self-management training and training of the patient's environment, strengthening exercises, psychological support, diet therapy.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 3","pages":"292-299"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141617353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peculiarities of leadership qualities manifestation by modern managers of police organizations: psychological aspect.","authors":"Ivan M Vyhivskyi, Ivan М Okhrimenko, Dmytro V Shvets, Maksym V Korniienko, Oleksandr H Komisarov, Olga M Smirnova","doi":"10.36740/Merkur202405112","DOIUrl":"https://doi.org/10.36740/Merkur202405112","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To study the psychological peculiarities of the manifestation of leadership qualities by modern managers of police organizations..</p><p><strong>Patients and methods: </strong>Materials and Methods: The research conducted in 2022-2024 involved 64 mid-level managers of police organizations and 462 officers from police units directly subordinated to these managers. Research methods: bibliosemantic, psychological and diagnostic, system analysis and generalization method, statistical.</p><p><strong>Results: </strong>Results: It has been found that a significant number of modern mid-level managers of police organizations are not inclined to show leadership in their units. It has been found that 15,6% of today's mid-level managers demonstrate low leadership. The average level of leadership qualities was recorded in 50,0% of managers, and this result generally coincides with the opinion of officers (51,1%). A sufficient level of leadership qualities of managers, which ensures the effectiveness of their management activities, was identified in 34,4% of respondents. It has been determined that a third of the respondents in both groups (35,9% of managers; 33,3% of officers) believe that the efficiency of management activities is above average and can be improved through various measures and means.</p><p><strong>Conclusion: </strong>Conclusions: The obtained results indicate the practicality of using an integrated approach to developing leadership qualities and skills of successful team management (at the subsequent stages of work with personnel). Also this indicates problems in the organization of professional selection and psychological support of police managers.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 5","pages":"557-561"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The modern view of the use of extracorporeal detoxification in the treatment of drug poisoning (overdose).","authors":"Natalia V Kurdil, Vladislava V Andriushchenko, Oleh V Ivashchenko, Anton O Volosovets, Borys S Sheyman, Kateryna O Bobkovych, Borys I Palamar","doi":"10.36740/Merkur202405107","DOIUrl":"https://doi.org/10.36740/Merkur202405107","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To analyze the results of the application of extracorporeal detoxification methods in the treatment of drug poisoning and their complications..</p><p><strong>Patients and methods: </strong>Materials and Methods: The studied data of 129 patients aged 18-46 years with severe drug poisoning treated at the Kyiv toxicological center in 2010-2020. Statistical analysis was performed using the IBM SPSS Statistics 29.0.0.0 program; Kaplan-Meier method, log-rank test, p<0,05.</p><p><strong>Results: </strong>Results: Patients who started receiving renal replacement therapy 24-36 hours after hospitalization had the highest Kaplan-Meier survival rates. The Kaplan-Meier hazard ratio for death shows that the chances of survival progressively decrease from the 48th to the 72nd hour from the moment of admission of patients to hospital, and this trend is observed in patients with both anuria and oliguria. There was a statistically significant difference in Kaplan-Meier survival in patients receiving selective hemoperfusion on the background of renal replacement therapy (p=0,017); ozone therapy (p=0,051) and plasmapheresis (p=0,131) did not show statistical significance.</p><p><strong>Conclusion: </strong>Conclusions: The combination of various methods of extracorporeal detoxification helps to increase the effectiveness of treatment of patients with drug poisoning due to the acceleration of the elimination of toxic substances and reduces the degree of manifestation of organotoxic effects.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 5","pages":"522-528"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indicators of oxidative stress in the organs of the reproductive system of rats under conditions of long-term ethanol exposure.","authors":"Sergiy O Nesteruk, Yaroslav O Bilyk, Ivan M Klishch, Oksana M Matolinets, Olena A Yakymchuk, Viktor V Tverdochlib","doi":"10.36740/Merkur202405104","DOIUrl":"https://doi.org/10.36740/Merkur202405104","url":null,"abstract":"<p><strong>Objective: </strong>. Aim: To investigate changes in oxidative stress indicators in rats under conditions of long-term ethanol exposure.</p><p><strong>Patients and methods: </strong>Materials and Methods: We studied the effect of prolonged exposure to ethanol on the activity of free radical processes in the gonads of rats of both sexes. Experimental animals were divided into 2 groups: Group I (control group) rats, which were injected with distilled water orally for 28 days; II group - which for 28 days were injected intragastrically with a 30% ethanol solution at the rate of 2ml/100g of body weight once a day.</p><p><strong>Results: </strong>Results: The conducted experimental studies showed that the level of free radicals increases in animals that were injected with ethanol for 28 days, as indicated by an increase in the ROS index by 1.6 times in males and 1.7 times in females. Lipid peroxidation processes are also activated, as evidenced by an increase in the level of initial products of the lipoperoxidation chain - HPL by 54.6%, intermediate products - TBP by 57.9% and final products - SHO - by 80.3% in males and by 68.2%, respectively , 80.9% and 84.6% in females. Along with this, the activity of oxidative modification of proteins in the organs of the reproductive system of the experimental group of animals also increased. In particular, the level of OMР370 in the testes of male rats increased by 89.1%, and OMР430 increased by 56.4% from the level of animals that were not given ethanol. In the ovaries of female rats, the level of OMР370 increased by 112.%, and OMР430 increased by 60.7% from the level of animals without simulating ethanol intoxication. Therefore, we were able to establish significant changes and disturbances in the processes of free radical oxidation in the organs of the reproductive system of animals under the toxic effect of ethanol, which can negatively affect the reproductive function and quality of offspring in animals that were simulated ethanol intoxication.</p><p><strong>Conclusion: </strong>Conclusions: In animals of both sexes, under the conditions of chronic ethanol exposure, there is an increase in free radical oxidation indicators, namely ROS, lipid peroxidation, oxidative modification of proteins, and the growth indicators in females are more significant than in males. This indicates a negative effect of chronic ethanol intoxication on the state of the membrane structures of germ cells, with DNA damage, which can lead to a violation of the function of the genital organs.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 5","pages":"500-504"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of the COVID-19 pandemic and martial law on the health and physical fitness of Ukrainian students.","authors":"Grygoriy P Griban, Nataliia Liakhova, Mykola O Nosko, Yuliia M Nosko, Oksana P Kanishcheva, Halyna Yu Kurtova, Tеtiana O Stechenko","doi":"10.36740/Merkur202406106","DOIUrl":"https://doi.org/10.36740/Merkur202406106","url":null,"abstract":"<p><strong>Objective: </strong>Aim: The aim is to study the impact of prolonged quarantine related to COVID-19 and martial law on the health and physical fitness of students in Ukrainian higher educational institutions..</p><p><strong>Patients and methods: </strong>Materials and Methods: Research methods: literature analysis, surveys, testing of students' health and physical fitness, methods of mathematical statistics. The research was conducted in 2019-2023. The survey involved 462 (143 males and 319 females) students. Health assessments and physical fitness tests were conducted with second-year students (before quarantine (2019): males - n = 63; females - n = 78; after quarantine (2023): males - n = 51; females - n = 67).</p><p><strong>Results: </strong>Results: The negative attitude of the majority of students (66.4 % of men and 76.5 % of women) to distance learning in physical education was revealed. A significant deterioration of all studied indicators of students' health and physical fitness during the quarantine period related to COVID-19 and martial law in Ukraine was revealed.</p><p><strong>Conclusion: </strong>Conclusions: Since the state of health and level of physical fitness of students is the main criterion for the effectiveness of physical education in higher educational institutions of Ukraine, physical education departments should focus their work on modernizing traditional and developing new forms and methods of physical education, shaping students' civic consciousness and behavior, their readiness to serve society and protect the state with dignity.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 6","pages":"654-659"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143417109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biological treatment in chronic disease management: from asthma to ulcerative colitis. A review paper.","authors":"Karolina Szczygieł, Kacper Sukiennicki, Iwon Grys","doi":"10.36740/Merkur202404109","DOIUrl":"https://doi.org/10.36740/Merkur202404109","url":null,"abstract":"<p><strong>Objective: </strong>Aim: The purpose of this article is to review the literature on the applicability of biologic agents, their mechanism of action, safety and factors affecting their choice in selected chronic conditions: asthma, psoriasis, ankylosing spondylitis and ulcerative colitis.</p><p><strong>Patients and methods: </strong>Materials and Methods: The electronic databases MEDLINE/PubMed and ScienceScholar were searched for studies published in English and Polish and indexed from 2018 to April 2024. Dodatkowo uwzględniono Stanowisko Polskiego Towarzystwa Alergologicznego i Polskiego Towarzystwa Chorób Układu Oddechowego, rekomendacje Polskiego Towarzystwa Dermatologicznego, wytyczne Polskiego Towarzystwa Gastroenterologii i konsultanta krajowego w dziedzinie gastroenterologii oraz wytyczne Global Initiative for Asthma (GINA).</p><p><strong>Conclusion: </strong>Conclusions: 1. Biological therapy demonstrates a significant reduction in the severity of clinical symptoms and complications associated with a variety of disease entities. An additional value of this therapy is its effectiveness among patients who do not respond to traditional treatment strategies. 2. In the perspective of the future of biologic treatment, it is important to study potential interactions between biologic drugs and other therapeutic methods. 3. To maximize benefits while minimizing complications, requires an individualized approach for each patient.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 4","pages":"439-444"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142366846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Youth's internet dependence forming factors as a global public health problem.","authors":"Ivan М Okhrimenko, Svitlana S Okhrimenko, Alla V Marchuk, Vadym A Kudinov, Oleksandr Ye Pakrysh, Valentyna O Tyurina, Nataliia Liakhova","doi":"10.36740/Merkur202404106","DOIUrl":"https://doi.org/10.36740/Merkur202404106","url":null,"abstract":"<p><strong>Objective: </strong>Aim: The aim is to study the main factors of youth's Internet dependence formation.</p><p><strong>Patients and methods: </strong>Materials and Methods: We conducted psychodiagnostic examination of students in the National Academy of Internal Affairs. The research involved 154 students: full-time students aged 18-25 (n = 78) and part-time students aged 26-35 (n = 76).</p><p><strong>Results: </strong>Results: The degree of prevalence of various types of Internet dependence among young people was determined. It was determined that the problem of Internet dependence requires consideration of socio-demographic, socio-psychological, individual, and psychological, as well as organizational factors.</p><p><strong>Conclusion: </strong>Conclusions: It was found that the number of Internet-dependent people among youth is currently growing rapidly. The most favorable individual-typological properties of a personality for the development of Internet dependence are introversion, anxiety, sensitivity, and aggressiveness. Internet dependence is a type of social dependence. An Internet-dependent individual suffers from the inability to maintain harmonious interpersonal contacts and resolve personal issues that are distorted by the virtual environment. Deviations from normal behavior in society change the peaceful way of life and affect public health.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 4","pages":"421-426"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142366857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Annual survival of patients with end-stage chronic kidney disease on supportive hemodialysis and its correlates.","authors":"Saule Bodessova, Bagdat Sultanova, Nazira Bekenova, Zhanar Mursalova","doi":"10.36740/Merkur202404102","DOIUrl":"10.36740/Merkur202404102","url":null,"abstract":"<p><strong>Objective: </strong>Aim: The aim of the study was to determine the relationship of residual renal function, markers of inflammation and protein-energy expenditure with annual survival in patients undergoing hemodialysis.</p><p><strong>Patients and methods: </strong>Materials and Methods: The work was a prospective cohort study and included 299 patient data. Residual kidney function was determined by urine volume of more than 250 ml per day to assess the effect. According to this criterion, the patients were divided into two groups. The degree of chronic inflammation was assessed by the content of acute phase proteins (ferritin and C-reactive protein) in the blood serum. The serum albumin level was chosen as a marker of protein-energy expenditure. The survival rate of patients with residual renal function was higher as compared to patients without it (p<0.001).</p><p><strong>Results: </strong>Results: In the current study, the absence of residual kidney function increased the risk of mortality from all causes in patients who had recently undergone hemodialysis by almost 30 times during the first year of substitution therapy. C-reactive protein was also associated with poorer survival in these patients (HR=1.01; 95% CI: 1-1.02), while albumin was inversely associated with mortality (HR=0.92; 95% CI: 0.87-0.98).</p><p><strong>Conclusion: </strong>Conclusions: Thus, residual renal function and higher serum albumin levels by the time maintenance hemodialysis begins are independent predictors of the best survival during the first year of replacement therapy. The presence of residual kidney function of less than 250 ml and a higher level of C-reactive protein correlated with an increased risk of mortality in these patients.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 4","pages":"392-399"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142366845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abnormal uterine bleeding and its causes. Literature review.","authors":"Liudmyla A Vygivska, Lesia A Rudenko, Olesia O Pliekhova, Igor Yu Rakytianskyi","doi":"10.36740/Merkur202404112","DOIUrl":"10.36740/Merkur202404112","url":null,"abstract":"<p><p>Based on the analysis of information from available sources of scientific literature, the article provides an overview of the problem of abnormal uterine bleeding and its causes. Preservation of women's reproductive health is an urgent problem of the whole world. AUB is a debilitating symptom that affects a large number of women and one of the most common gynecological abnormalities. АUB, as a rule, does not threaten a woman's life, but significantly decreases its quality. Menstrual disorders affect all aspects of a woman's life, even increasing the risk of premature death. Women with AUB are more likely to seek medical care due to social and physical factors, while 50% of female patients have mental health problems due to anxiety and depression. Structural causes of uterine bleeding increase as a woman ages, which can affect reproductive health. Extragenital disorders are considered one of the most frequent causes of AUB. This is explained by the features of the endometrium, the state of which is influenced by general changes in a woman's hormonal status and the functional state of some organs and systems. AUB can be caused by diseases of the thyroid gland, uncorrected diabetes, obesity, blood coagulation disorders (most often von Willebrand's disease), infectious diseases, certain drugs (corticosteroids, antipsychotic or antiepileptic drugs), climate change and diet, psychological stress, etc. Management of patients with abnormal uterine bleeding is a complex problem that should include assessment of gynecological status and consultation of related specialists (endocrinologists, cardiologists, etc.).</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"52 4","pages":"457-461"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142366844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}