Polski Merkuriusz Lekarski最新文献

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Conflict-induced increase in viral hepatitis and human immunodeficiency virus infection among internally displaced persons: a retrospective study in Volodymyr community, Ukraine. 冲突引起的国内流离失所者病毒性肝炎和人类免疫缺陷病毒感染的增加:乌克兰Volodymyr社区的回顾性研究。
Polski Merkuriusz Lekarski Pub Date : 2025-01-01 DOI: 10.36740/Merkur202503115
Ivan S Chervynskyy, Nataliia Yu Kondratiuk
{"title":"Conflict-induced increase in viral hepatitis and human immunodeficiency virus infection among internally displaced persons: a retrospective study in Volodymyr community, Ukraine.","authors":"Ivan S Chervynskyy, Nataliia Yu Kondratiuk","doi":"10.36740/Merkur202503115","DOIUrl":"https://doi.org/10.36740/Merkur202503115","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To study the trends in the prevalence of hepatitis B (HBV), hepatitis C (HCV), and human immunodeficiency virus (HIV) infection during 2020-2024 in the rear region of Ukraine, in the city of Volodymyr, and assess the impact of internal displacement on the spread of infectious diseases.</p><p><strong>Patients and methods: </strong>Materials and Methods: A retrospective analysis in Volodymyr Hospital (Volodymyr, Ukraine) was conducted using data from the official clinical registry and ELISA (enzyme-linked immunosorbent assay) for 2020-2024. Comparative literature and statistical data from infection prevention programmes were also analyzed.</p><p><strong>Results: </strong>Results: The decline in officially reported new HIV infections (from 29 in 2020 to 7 in 2024) contrasted with a marked increase in the number of ELISA-tested cases of hepatitis B and C (7,974 and 6,705 in 2024, respectively). Internally displaced persons (IDPs) accounted for a significant proportion of new diagnoses after 2022, including 22 HBV and 17 HCV cases in 2022. The discrepancy between laboratory results and official reporting suggests underdiagnosis. Additionally, Poisson regression analysis demonstrated that IDP status was a significant factor for increased risk of blood-borne infections.</p><p><strong>Conclusion: </strong>Conclusions: Military conflict and population displacement significantly exacerbate the problem of blood-borne infections. Countries with successful infection control systems, such as Canada and the Netherlands, have implemented universal HBV vaccination, national HCV elimination strategies, and mobile care for vulnerable populations. These examples highlight the need to replicate such models in conflict-affected regions. National plans should be based on international recommendations, such as the WHO Global Health Strategy 2022 and the US Centers for Disease Control and Prevention's viral hepatitis elimination roadmap.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 3","pages":"395-402"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single and combined effects of lead and piroxicam on the structural and functional profiles of the liver and kidney. 铅和吡罗昔康对肝脏和肾脏的结构和功能的单一和联合影响。
Polski Merkuriusz Lekarski Pub Date : 2025-01-01 DOI: 10.36740/Merkur202503105
Iqbal A Ai-Rufaei, Sawsan A Ali, Dhuha Adel Kareem, Majdy Faisal Majeed
{"title":"Single and combined effects of lead and piroxicam on the structural and functional profiles of the liver and kidney.","authors":"Iqbal A Ai-Rufaei, Sawsan A Ali, Dhuha Adel Kareem, Majdy Faisal Majeed","doi":"10.36740/Merkur202503105","DOIUrl":"https://doi.org/10.36740/Merkur202503105","url":null,"abstract":"<p><strong>Objective: </strong>Aim: Our study investigated the harmful synergistic effect of lead and piroxicam treatment on liver and kidney tissue functions and morphology.</p><p><strong>Patients and methods: </strong>Materials and Methods: 24 male Wister rats were allocated randomly in equal numbers n=6 into four groups: (Group1): was used as the control animal group. In the control group, 0.5 mL of distilled water was given by an orogastric tube. (Group2): for 21 days, lead acetate was administered via an orogastric tube at a dose of 4 mg/kg/day according to body weight. (Group3): is given peroxicam (0.3 mg/kg/day) by the same route and dose for 21 days. Group 4: (Group4), a synergistic mixture of piroxicam (1 mg/kg/day) and lead acetate (4 mg/kg/day) was given by an orogastric tube. Liver functions were evaluated by measuring activity of alanine aminotransferase aspartate aminotransferase and alkaline phosphatase. Kidney functions were represented by assays of blood urea nitrogen, creatinine, and urea, while antioxidant status determined by malondialdehyde catalase activity and reduced-glutathione level.</p><p><strong>Results: </strong>Results: Liver and renal function data were estimated in serum and organs. Group2 and Group3 caused elevated serum levels of MDA, BUN, and Cre while decreasing levels of SOD and GSH in serum and liver and kidney tissue. Group4: Administration of a synergistic mixture of lead and piroxicam caused severe elevated serum levels of MDA, BUN, and Cre, while acutely decreasing levels of SOD and GSH were found in serum and liver and kidney tissue. Generally, data supported by histological examination indicated severe damage following induced oxidative stress by a synergistic mixture of piroxicam and lead compared with other groups.</p><p><strong>Conclusion: </strong>Conclusions: The synergistic treatment (group 4) resulted in the most significant effects compared to the control group, as evidenced by both biochemical and histopathological measurements. Additionally, groups 2 and 3 showed negative changes in these measurements relative to the control group, but these changes were less pronounced than those observed in group 4.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 3","pages":"328-335"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Applications of magnetic resonance imaging in the diagnosis of posttraumatic stress disorder. 磁共振成像在创伤后应激障碍诊断中的应用。
Polski Merkuriusz Lekarski Pub Date : 2025-01-01 DOI: 10.36740/Merkur202502117
Barbara Paraniak-Gieszczyk
{"title":"Applications of magnetic resonance imaging in the diagnosis of posttraumatic stress disorder.","authors":"Barbara Paraniak-Gieszczyk","doi":"10.36740/Merkur202502117","DOIUrl":"10.36740/Merkur202502117","url":null,"abstract":"<p><p>The application of magnetic resonance imaging (MRI) techniques in diagnosing posttraumatic stress disorder (PTSD) represents a significant research focus, providing deeper insights into trauma-related psychological disorders. PTSD often arises from chronic stress, a state in which the body struggles to adapt to overwhelming stimuli. Patients frequently experience persistent flashbacks (intrusive memories or sensory recollections of the traumatic event) and nightmares, which evoke intense emotional responses and disrupt daily life. These recurring episodes of stress and anxiety severely impact behavior and functioning. Understanding the brain changes associated with PTSD has become possible through advancements in MRI studies. This article aims to review the scientific literature on the use of magnetic resonance imaging techniques in diagnosing posttraumatic stress disorder. The review is based on scientific literature from medical databases, including Web of Science and Scopus, covering publications up to October 30, 2024. The findings from this analysis may contribute to a better understanding of the neurobiological mechanisms underlying PTSD.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 2","pages":"273-276"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The prediction power of thymidine phosphorylase and IL-6 in the relapse of breast cancer. 胸苷磷酸化酶和IL-6对乳腺癌复发的预测能力。
Polski Merkuriusz Lekarski Pub Date : 2025-01-01 DOI: 10.36740/Merkur202501112
Ahmed Hussein Zwamel, Hind Mizhir Mousa, Bushra A M Abdul Azeez, Ali A Al-Fahham
{"title":"The prediction power of thymidine phosphorylase and IL-6 in the relapse of breast cancer.","authors":"Ahmed Hussein Zwamel, Hind Mizhir Mousa, Bushra A M Abdul Azeez, Ali A Al-Fahham","doi":"10.36740/Merkur202501112","DOIUrl":"10.36740/Merkur202501112","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To investigate the role of thymidine phosphate and IL-6 in the pathogenesis and survival rate in women with breast cancer..</p><p><strong>Patients and methods: </strong>Materials and Methods: Sixty women diagnosed with breast cancer (with age ranging between 25-65 years) were included in the current study. Of these, 40 women relapse after 6 months of follow up, while 40 patients were non-relapsed.</p><p><strong>Results: </strong>Results: Statistical analysis pointed out that thymidine phosphorylase may be significantly increased in relapsed women comparing to non-relapsed women (4.48±0.24 ng/ml and 1.12±0.18 ng/ml respectively, p value <0.0001). Regarding IL-6, the current study also found that IL-6 tends to be increased in relapse BC comparing to non-relapsed BC (8.6±0.92 pg/ml vs. 6.82±1.14 pg/ml respectively, p-value<0.0001. There was a high significant positive correlation between thymidine phosphorylase and IL-6 (r=0.368; p-value <0.01). The sensitivity and specificity in predicting relapse in breast cancer were 0.83 and 0.64 for TP and 0.78, and 0.65 respectively.</p><p><strong>Conclusion: </strong>Conclusions: It is suggested that thymidine phosphate activity and IL-6 serum levels after six months of follow up, have a dual synergistic impact on the pathogenesis of relapse for BC. These biomarkers can also be used in the prediction of relapse rate in women diagnosed with BC.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 1","pages":"88-93"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive approach to the rehabilitation of professionals with high levels of psychophysical stress, pain syndromes and type 2 diabetes mellitus during the war Lidiia V. Butska1,2,3, Oksana O. Drevitska1,2,3, Sergei V. Dybkalyuk4, Valentyn O. Ryzhak 5 1TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV, KYIV, UKRAINE 2INTERREGIONAL ACADEMY OF PERSONNEL MANAGEMENT, KYIV, UKRAINE 3STATE INSTITUTION «KUNDIIEV INSTITUTE OF OCCUPATIONAL HEALTH OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE», KYIV, UKRAINE 4SHUPYK NATIONAL HEALTHCARE UNIVERSITY OF UKRAINE, KYIV, UKRAINE 5OPTIMUM MEDIA UKRAINE, KYIV, UKRAINE. 对战争期间患有高水平心理生理压力、疼痛综合征和2型糖尿病的专业人员的综合康复方法Lidiia V. Butska1、2,3、Oksana O. Drevitska1、2,3、Sergei V. Dybkalyuk4、Valentyn O. Ryzhak 5、taras SHEVCHENKO乌克兰基辅国立大学2乌克兰基辅地区间人事管理学院3国立机构“乌克兰国家医学科学院KUNDIIEV职业健康研究所”乌克兰基辅4shupyk乌克兰国立卫生保健大学,乌克兰基辅5乌克兰最佳媒体,乌克兰基辅。
Polski Merkuriusz Lekarski Pub Date : 2025-01-01 DOI: 10.36740/Merkur202501105
{"title":"Comprehensive approach to the rehabilitation of professionals with high levels of psychophysical stress, pain syndromes and type 2 diabetes mellitus during the war Lidiia V. Butska1,2,3, Oksana O. Drevitska1,2,3, Sergei V. Dybkalyuk4, Valentyn O. Ryzhak 5 1TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV, KYIV, UKRAINE 2INTERREGIONAL ACADEMY OF PERSONNEL MANAGEMENT, KYIV, UKRAINE 3STATE INSTITUTION «KUNDIIEV INSTITUTE OF OCCUPATIONAL HEALTH OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE», KYIV, UKRAINE 4SHUPYK NATIONAL HEALTHCARE UNIVERSITY OF UKRAINE, KYIV, UKRAINE 5OPTIMUM MEDIA UKRAINE, KYIV, UKRAINE.","authors":"","doi":"10.36740/Merkur202501105","DOIUrl":"10.36740/Merkur202501105","url":null,"abstract":"<p><strong>Objective: </strong>. Aim: To evaluate the effectiveness of a multilevel rehabilitation program integrating physiotherapy (PT), transcranial electrical stimulation (TES), and endonasal breathing of a singlet-oxygen mixture (EBSO) on pain syndromes (PS), quality of life (QL), and levels of depression in professionals with type 2 diabetes mellitus (T2DM) and high psychophysical stress.</p><p><strong>Patients and methods: </strong>Materials and Methods: Sixty professionals with high psychophysical stress were randomly divided into three groups (n=20 each). Group 1 received standard rehabilitation. Group 2 underwent targeted PT, including ultrasound therapy for the pancreas projection and magneto-laser therapy for the liver projection and Th5-Th7 zones. Group 3 received the same PT as Group 2, supplemented with TES (alpha rhythm frequency) and EBSO. The rehabilitation program lasted two weeks, comprising 10 sessions. Outcomes were assessed using the QL questionnaire - SF-36 and Beck Depression Inventory-II (BDI-II).</p><p><strong>Results: </strong>Results: Group 3 demonstrated significant improvements in QL by SF-36 score, particularly in Physical Functioning (from 49,2 ± 2,6 to 70,3 ± 3,8), Bodily Pain (from 48,1 ± 2,6 to 69,3 ± 3,1), and Mental Health (from 38,0 ± 3,3 to 59,3 ± 3,6; p < 0,01). Depression score decreased from 30,6 ± 2,1 to 18,2 ± 2,0 (p < 0,01), with notable improvements in cognitive-affective and somatic subscales. Group 2 showed moderate improvements, while Group 1 exhibited minimal changes.</p><p><strong>Conclusion: </strong>Conclusions: Combining targeted PT with TES and EBSO significantly improves somatic and psychological outcomes in T2DM patients compared to standard rehabilitation or PT alone.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 1","pages":"34-39"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The efficacy of novel antibiotics against multi-drug-resistant Staphylococcus aureus: a preclinical in vitro study. 新型抗生素对多重耐药金黄色葡萄球菌的疗效:临床前体外研究。
Polski Merkuriusz Lekarski Pub Date : 2025-01-01 DOI: 10.36740/Merkur202502108
Baraa Bahaa Aldin, Safa Nihad Abed Shubar, Hiba Khalaf
{"title":"The efficacy of novel antibiotics against multi-drug-resistant Staphylococcus aureus: a preclinical in vitro study.","authors":"Baraa Bahaa Aldin, Safa Nihad Abed Shubar, Hiba Khalaf","doi":"10.36740/Merkur202502108","DOIUrl":"https://doi.org/10.36740/Merkur202502108","url":null,"abstract":"<p><strong>Objective: </strong>Aim: This preclinical study was oriented towards evaluating the efficiency of newly developed antibiotics against a selection of multi-drug-resistant Staphylococcus aureus strains, with the broader aim of finding a potent candidate to counteract the increasing resistance issue.</p><p><strong>Patients and methods: </strong>Materials and Methods: The study utilized four distinct strains of multi-drug-resistant Staphylococcus aureus (SA-1 to SA-4) and three novel antibiotics (NA-1 to NA-3) under controlled laboratory conditions. The bacterial strains were cultured in vitro, and a series of tests including drug susceptibility testing and the determination of minimum inhibitory concentrations (MIC) were conducted. Statistical analysis was carried out using two-way ANOVA and Bonferroni post-hoc tests to analyze the significance of the observed results.</p><p><strong>Results: </strong>Results: Our data showcased variations in the growth characteristics and resistance profiles of the different strains, helping in identifying the most potent antibiotic among the tested compounds. Notably, antibiotic NA-1 manifested the lowest MIC values against the strains SA-1 and SA-3, indicating a higher potency (p < 0.01). Moreover, NA-1 exhibited significantly lower MIC₅₀ and MIC₉₀ values (0.56 μg/mL and 0.95 μg/mL, respectively), suggesting that it had the best inhibitory power amongst the antibiotics tested against a majority of the strains (p < 0.05).</p><p><strong>Conclusion: </strong>Conclusions: The findings from this preclinical in-vitro study accentuate the potential of novel antibiotic NA-1 as a promising candidate in combatting multidrug- resistant Staphylococcus aureus strains. However, further research, including in-vivo studies, is requisite to substantiate the efficacy of this antibiotic in a clinical setting.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 2","pages":"203-211"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of colectomy on the quality of life in patients with chronic slow-transit constipation according to the pac-qol scale, depending on the histological subtype of the colonic wall. 根据pac-qol量表,结肠切除术对慢性慢传输型便秘患者生活质量的影响,取决于结肠壁的组织学亚型。
Polski Merkuriusz Lekarski Pub Date : 2025-01-01 DOI: 10.36740/Merkur202503111
Ivan M Leshchyshyn, Leonid Yu Markulan, Olga I Okhotska, Pavlo L Byk
{"title":"The impact of colectomy on the quality of life in patients with chronic slow-transit constipation according to the pac-qol scale, depending on the histological subtype of the colonic wall.","authors":"Ivan M Leshchyshyn, Leonid Yu Markulan, Olga I Okhotska, Pavlo L Byk","doi":"10.36740/Merkur202503111","DOIUrl":"https://doi.org/10.36740/Merkur202503111","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To assess the quality of life using the PAC-QOL scale in patients with chronic slow-transit constipation depending on the histological subtypes of the colonic wall after colectomy.</p><p><strong>Patients and methods: </strong>Materials and Methods: The dynamics of quality-of-life scores were studied in 107 patients with slow-transit constipation resistant to conservative treatment after colectomy using PAC-QOL questionnaire.</p><p><strong>Results: </strong>Results: Significant improvement in quality of life was observed for all PAC-QOL subscales one year after surgery: physical discomfort improved by 58.7% to 67.7%, psychological discomfort - by 50.5%-67.2%, worries and concerns - by 53.3%- 67.6%, satisfaction with treatment - by 80.7%-82.6%, the PACQOL score - by 54-67.9%. The best outcomes for the PAC-QOL scale were demonstrated in patients with cajal subtype - 67,9% compared to the neuropathic (54,0%), myopathic inflammatory (56,1%), histologically intact (61,2%). Cajal histological subtype showed a greater improvement in the physical discomfort score - 67,7%, compared to the histologically intact subtype (58,7%), and the neuropathic subtype (58,9%); for Psychosocial discomfort - 67,2% compared to the dystrophic myopathic (55,5%), the neuropathic (50,7%), and the myopathic inflammatory subtype (50,5%); for the worries and concerns - 67,6% compared to the neuropathic subtype (53,3%).</p><p><strong>Conclusion: </strong>Conclusions: In patients with STC resistant to conservative treatment, colectomy leads to significant improvement in quality of life according to the Pac-Qol questionnaire, one year after surgery with the best improvement for the Cajal subtype.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 3","pages":"367-377"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interactions between Covid-19 and chronic disease: A multilevel analysis of treatment strategies and outcomes. Covid-19与慢性疾病之间的相互作用:治疗策略和结果的多水平分析
Polski Merkuriusz Lekarski Pub Date : 2025-01-01 DOI: 10.36740/Merkur202503102
Yerzhan Zhunussov, Yevgeniya Li, Bakhyt Kosherova, Gheorghe Placinta, Xeniya Mkhitaryan
{"title":"Interactions between Covid-19 and chronic disease: A multilevel analysis of treatment strategies and outcomes.","authors":"Yerzhan Zhunussov, Yevgeniya Li, Bakhyt Kosherova, Gheorghe Placinta, Xeniya Mkhitaryan","doi":"10.36740/Merkur202503102","DOIUrl":"https://doi.org/10.36740/Merkur202503102","url":null,"abstract":"<p><strong>Objective: </strong>Aim: The purpose of study was to analyse the interaction between COVID-19 and chronic diseases, with a focus on evaluating the effectiveness of treatment strategies.</p><p><strong>Patients and methods: </strong>Materials and Methods: The study, conducted at the Infectious Disease Centre of the Regional Clinical Hospital of Karaganda, aimed to determine factors influencing therapy effectiveness in 236 COVID-19 patients. It assessed the dynamics of laboratory indicators and their relationship with chronic diseases like diabetes, hypertension, cardiovascular conditions, chronic respiratory diseases, and cancer. Demographic data, including age and gender, were also considered.</p><p><strong>Results: </strong>Results: The study revealed no significant age difference between patients with moderate and severe COVID-19 courses, with both groups averaging a similar age of 66 years. The duration of hospitalization was significantly longer for patients with severe disease, who required an average of 15 days, compared to 11 days for patients with moderate disease (p<0.001). Comorbidities, especially arterial hypertension and coronary artery disease, were common in patients with moderate disease but had less impact on outcomes compared to severe cases, where multiple chronic conditions were linked to higher mortality. Some treatments had a more pronounced effect in this group of patients, while others may have been less effective or had negative effects.</p><p><strong>Conclusion: </strong>Conclusions: The study highlights the critical impact of chronic diseases on the severity and outcomes of COVID-19, emphasizing the need for personalized, multidisciplinary treatment strategies that consider comorbidities to optimize patient outcomes.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 3","pages":"302-311"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of stress levels based on the type of behaviour in stressful situation among internally displaced persons after relocation from areas of active hostilities. 根据国内流离失所者从敌对行动活跃地区迁出后在紧张情况下的行为类型调查其紧张程度。
Polski Merkuriusz Lekarski Pub Date : 2025-01-01 DOI: 10.36740/Merkur202503103
Viacheslav V Stepanenko, Liudmyla M Romanets, Lyudmyla Y Petryshyn, Viktoriia І Stepanenko, Taras R Kulchytskyi, Nadiya O Fedchyshyn, Larysa Ya Fedoniuk
{"title":"Investigation of stress levels based on the type of behaviour in stressful situation among internally displaced persons after relocation from areas of active hostilities.","authors":"Viacheslav V Stepanenko, Liudmyla M Romanets, Lyudmyla Y Petryshyn, Viktoriia І Stepanenko, Taras R Kulchytskyi, Nadiya O Fedchyshyn, Larysa Ya Fedoniuk","doi":"10.36740/Merkur202503103","DOIUrl":"https://doi.org/10.36740/Merkur202503103","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;Aim: To compare indicators of the level of stress and the tendency to be exposed to stressogenic factors in internally displaced persons who moved from regions of active hostilities in the first three months after the full-scale Russian invasion.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Patients and methods: &lt;/strong&gt;Materials and Methods: The following diagnostic tools were used in the study: 1. \"Test for determining the level of stress\" (according to V. Shcherbatykh, adapted by H. Kharko ), the essence of which is to determine the level of stress of a person. The test contains several sections that are responsible for a certain sign of stress - intellectual, behavioral signs, emotional and physiological symptoms. 2. \"Questionnaire for self-diagnosis of the type of behavior in a stressful situation\" (according to V. Boyko), which allows you to identify reactions to stress and the tendency to be influenced by stressogenic factors depending on the type of behavior in a stressful situation. Analysis, synthesis, generalization, concretization, systematization, comparison, forecasting, and mathematical statistics were used to process, compare, evaluate, and interpret the obtained research results. Data processing was carried out using Jamovi 2.2.5 and RStudio 2024.04.1.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Results: The relevance of the topic deals with the importance of the need to preserve, develop and strengthen the health of the individual, in particular in the conditions of war, which appears as a serious stress factor that tests a person. A special category that requires research on the level of stress and the tendency to be influenced by stress factors are internally displaced persons who have moved from regions of active hostilities and have a whole set of problems related to the lack of housing, work, adaptation in a new place, establishing communication, finding new resources of existence, etc. Long-term stress has a negative effect on the human body, in particular on intellectual, behavioral, emotional, and physiological manifestations. Among 134 respondents, 92 women, 29 men and 13 respondents did not indicate their gender participated in the study. The average age of the respondents was: Me=36, Q 1=32, Q 3=44 (N =118); 16 respondents did not indicate their age. The distribution of respondents' age indicators was not subject to a normal distribution according to the Gaussian curve.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Conclusions: During the study of groups of internally displaced persons (hereinafter IDPs), which were formed according to time, gender and age criteria, moderate direct correlations were found between indicators of the level of stress and indicators of the tendency to be influenced by stressogenic factors, depending on the type of behavior in a stressful situation. Correlation is observed both for general indicators and component blocks of stress manifestations (intellectual, behavioral, emotional and physiological), which conf","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 3","pages":"312-320"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex features of chewing pressure in youth of the Ukrainian ethnic group. 乌克兰族青年咀嚼压力的性别特征。
Polski Merkuriusz Lekarski Pub Date : 2025-01-01 DOI: 10.36740/Merkur202503109
Rostyslav O Ivanov, Larysa A Sarafyniuk, Petro V Sarafyniuk, Natalia M Bandurka, Svitlana Yu Nesterova
{"title":"Sex features of chewing pressure in youth of the Ukrainian ethnic group.","authors":"Rostyslav O Ivanov, Larysa A Sarafyniuk, Petro V Sarafyniuk, Natalia M Bandurka, Svitlana Yu Nesterova","doi":"10.36740/Merkur202503109","DOIUrl":"https://doi.org/10.36740/Merkur202503109","url":null,"abstract":"<p><strong>Objective: </strong>Aim: Determin the magnitude of chewing pressure between different teeth on the right and left parts of the dental arches between young people of different sex of general groups and individual craniotypes.</p><p><strong>Patients and methods: </strong>Materials and Methods: The study used a quantitative approach, in particular, Fuji technology, Prescale MS. The system consists of a film, a scanner and special software, which allows you to obtain data on the distribution of pressure and its exact values. The participants were divided by gender - 118 girls and 104 boys, in whom one of the physiological bite types was detected. The determination of craniotypes was carried out using a cranial index. The following distribution of craniotypes among adolescents was established: dolichocephalyc, mesocephalyc, brachycephalyc.</p><p><strong>Results: </strong>Results: We found a significant difference between youth in chewing efficiency, there were sex differences in the values of occlusal load between the first, second, third, fourth and fifth teeth of the left and right parts of the dental arches. We analyzed the value of chewing pressure in boys and girls belonging to different craniotypes, but significant sex differences were not found in all craniometric groups.</p><p><strong>Conclusion: </strong>Conclusions: Gender differences were established in the magnitude of chewing pressure of incisors, canines, and premolars of the left and right parts of the dental arches when comparing groups of girls aged 16-20 and boys aged 17-21. The most significant sex differences were found in individuals with mesocephaly, the smallest in dolichocephaly.</p>","PeriodicalId":39518,"journal":{"name":"Polski Merkuriusz Lekarski","volume":"53 3","pages":"352-360"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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