Medicine Today最新文献

{"title":"Keratoacanthoma, Verruca Vulgaris Arising over Porokeratosis of Mibelli : A New Association","authors":"A. Asaduzzaman, Mohammad Lutfur Rahman Rahat, M. J. Uddin, Mohammod Abu Hena Chowdhury, Akm Rejaul Haque","doi":"10.3329/medtoday.v33i2.56068","DOIUrl":"https://doi.org/10.3329/medtoday.v33i2.56068","url":null,"abstract":"Introduction: This case report highlighting the presence of keratoacanthoma and verruca vulgaris over the lesion of porokeratosis of mibelli.\u0000Case Report: In this case a 50-year-old housewife came with large well-defined asymptomatic plaque over the upper part of back of the trunk for last 10 years. After evaluation we got the presence of keratoacanthoma and verruca vulgaris on the plaque of porokeratosis of mibelli.\u0000Discussion: Porokeratosis is a clonal expansion of keratinocytes. Among the neoplasm squmous cell carcinoma (SCC) is the most commonly reported malignancy in porokeratosis. But in our case we didn’t find lesion of SCC. Porokeratosis of Mibelli, Keratoacanthoma and Verruca vulgaris have an association with human papilloma virus(HPV). This eithopathogenesis may be related to our clinical finding.\u0000Conclusion: There were reporting of squmous cell carcinoma or keratoacanthoma on Porokeratosis of Mibelli. But in our case we found both Keratoacanthoma and Verruca Vulgaris over Porokeratosis of Mibelli.\u0000Medicine Today 2021 Vol.33(2): 172-175  ","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"96 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87522684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Space Closure Rate in Mandibular Canine Retraction by Ni-Ti Closed Coil Spring: A Clinical Trial","authors":"Md Kamrul Hasan, G. Hassan, S. Rahman, Md Sher Ali, Md Azizur Rahman, M. Hasan, Rokeya Rahman Tani","doi":"10.3329/medtoday.v33i2.56050","DOIUrl":"https://doi.org/10.3329/medtoday.v33i2.56050","url":null,"abstract":"Introduction: In Majority of patients seeking orthodontic treatment, teeth must be extracted in order to obtain proper esthetics, occlusion, and stability as well as extraction of teeth is often a need to close residual space, after the initial decrowding and aligning. Pre adjusted fixed orthodontic appliances commonly utilize sliding mechanics for space closure with different types of force delivery systems. A variety of materials have been used as force delivery systems to close spaces between teeth as in the case of canine retraction after the extraction of premolars. Among all sliding or frictionless methods of canine retraction, super-elastic nickel titanium coil spring has a particular property in producing light continuous force at a long range of action, compared with previously available materials. Nickel-titanium closed coil spring, with a continuous action, might have some advantages in fixed appliance space closure mechanics.\u0000Materials and Methods: Over the period of one year from May 2015 to April 2016, this clinical trial was carried out and A total number of 20 patients (40 quadrants), who required canine retraction into first premolar extraction sites as part of their orthodontic treatment in the Department of Orthodontics of BSMMU selected as study population. The quadrants were affixed by nickel titanium closed coil springs (medium force, Ni-Ti extension spring, Ormco) with 200gm force measured by Correx Tension Gauge. Space closure was measured by means of direct measurement from the mesial surface of mesial wing of the 2nd premolar bracket and the distal surface of distal wing of the canine bracket with digital Vernier Calipers.\u0000Results: Mean space closer rate in mandibular canine retraction was 1.07 ± 0.12 mm/month by nickel-titanium (Ni-Ti) closed coil spring method with p value<0.001.\u0000Conclusion: This study revealed that space closer rate in mandibular canine retraction by nickel-titanium (Ni-Ti) closed coil spring is 1.07 ± 0.12 mm/month.\u0000Medicine Today 2021 Vol.33(2): 90-93","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85187376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Profile and Outcome of Acute Poisoning Cases in Children Living in a Rapidly Urbanizing Area","authors":"M. N. Islam, Naimur Rahman Ringku, Md. Saiful Islam","doi":"10.3329/medtoday.v33i2.56064","DOIUrl":"https://doi.org/10.3329/medtoday.v33i2.56064","url":null,"abstract":"Introduction: Acute poisoning is a common childhood emergency in Bangladesh. In many cases history and clinical features fail to identify the offending agent. This study was done to identify the specific clinical findings related with the source of poisoning and assess the outcome.\u0000Materials and Methods: It was a prospective study done from January to June 2020, among 75 indoor children of Tangail District Hospital. A preformed structured questionnaire was filled up by data collected from direct interview with the parents or caregivers, hospital records, during clinical examination.\u0000Results: We found the mean age of the study population 5.5±1.5 years having male preponderance 1.6:1 in ratio. Kerosene 16(21.33%) and organophosphorus compound 15(20%) were the most common etiological agents and accidental (85%) was the most common mode of poisoning. Most of the cases were asymptomatic 25(33.3%). We encountered only 5(6.6%) death having 62(82.6%) complete recovery.\u0000Conclusion: Acute poisoning still remains a major cause of child death in Bangladesh. History remains the main information for early diagnosis. We should take necessary steps to prevent exposure to poisonous material in children to reduce related burden of hospitalization, mortality and morbidity.\u0000Medicine Today 2021 Vol.33(2): 156-159","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91128386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of Red Blood Cell Distribution Width in Patients with Primary Cutaneous Vasculitis Compared to Systemic Vasculitis","authors":"Farhana Wahab, M. J. Uddin, A. Asaduzzaman, Mohammod Abu Hena Chowdhury, H. Mahmud, Rehnuma Nasim","doi":"10.3329/medtoday.v33i2.56049","DOIUrl":"https://doi.org/10.3329/medtoday.v33i2.56049","url":null,"abstract":"Introduction: Red blood cell distribution width (RDW) has been considered as an inflammatory marker in various disorders. Evaluation of RDW value can also be used as a novel and additional marker for differentiating systemic vasculitis from primary cutaneous vasculitis. Objective: To compare RDW value between patients with cutaneous vasculitis with systemic vasculitis, thereafter to find out it's role as an effective indicator to distinguish both forms of vasculitis.\u0000Materials and Methods: This cross sectional observational study was conduct between from July 2016 to December 2017. Total of 48 patients were divided into primary cutaneous vasculitis and systemic vasculitis. Blood was collected in EDTA tube to measure RDW value. Patient’s disease activity also scored and plotted according to Birmingham vasculitis activity score. Statistical analysis was performed by using SPSS.\u0000Results: Significantly high mean RDW were found in patients with systemic vasculitis compared to primary cutaneous vasculitis (15.09±0.92 vs. 13.48±1.1, p = 0.000). BVAS was significantly greater (13.93±5.10 vs. 4.87±2.69, p = < 0.001) in systemic vasculitis as well as in patients with high RDW group (11.73±5.71 vs. 5.37±3.96, p = < 0.001). Optimal RDW cut off point for differentiating systemic vasculitis from cutaneous vasculitis was 14.2 with 81.3% sensitivity and 81.2% specificity.\u0000 Conclusion: Present study revealed importance of RDW monitoring along with disease activity in patients with any form of vasculitis. Systemic vasculitis had higher level of RDW. So RDW can be considered as a marker to discriminate systemic vasculitis from primary cutaneous vasculitis.\u0000Medicine Today 2021 Vol.33(2): 84-89","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80332409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coexistence of Pelviureteric Junction Obstruction and Vesicoureteral Reflux","authors":"M. Asaduzzaman, S. Abdullah, M. Hanif, M. Hasanuzzaman, Rifat Islam, S. Islam","doi":"10.3329/medtoday.v33i2.56051","DOIUrl":"https://doi.org/10.3329/medtoday.v33i2.56051","url":null,"abstract":"Introduction: The most common upper urinary tract problem in children is obstruction at the pelviureteric junction. It happens with varying degrees of seriousness. Ultrasonography and DTPA (Diethylene Triamine Penta-acitic Acid) renography are commonly used to detect it. Objective: To find out the coexistence of ipsilateralpelviureteric junction obstruction with vesicourenteral reflux.\u0000Materials and Methods: This prospective study was conducted in the Department of Paediatric Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from January 2006 to May 2007 over a period of 1 year 5 months. Thirty-five patients with unilateral hydronephrosis due to PUJ obstruction were included in this study (age: 1 month-15 years). Results were analyzed using Statistical Package for Social Science (SPSS).\u0000Results: Incidence of Vesicoureteral reflux (VUR) among pelviureteric junction (PUJ) obstruction patients was 8.6%. Of them Grade-I VUR was 33.3% and grade-II VUR was 66.7%. Mean age of the patients was 4.71 ± 1.97 years and with VUR was 9.33 ± 4.93 years. Male to female ratio was 4:1. Only 5.7% mothers had regular antenatal checkup and 28.5% had irregular. Majority of the patients 28 (80%) were presented with painless loin mass, 6 (17.1%) with fever, 8 (22.9%) with loin pain and 8 (22.9%) with failure to thrive. Three patients (8.6%) showed abnormal R/M/E and all of the abnormal R/M/E samples showed positive culture.\u0000Conclusions: Incidence of Vesicoureteral reflux (VUR) among pelviureteric junction (PUJ) obstruction patients was 8.6%.\u0000Medicine Today 2021 Vol.33(2): 94-97","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"314 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91313484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Covid-19 Pandemic on Mental Health","authors":"S. Akhter, A. Rizwan","doi":"10.3329/medtoday.v33i2.56067","DOIUrl":"https://doi.org/10.3329/medtoday.v33i2.56067","url":null,"abstract":"Introduction: The year 2019 will be remembered in the human history by the mark of an unknown diseases plaguing the whole world with its devastation, namely coronavirus disease 2019 (COVID-19). This pandemic caused by a novel strain of RNA virus has caused a catastrophic health outcome for millions of world citizens but in many cases only the physical aspect of the disease came under consideration.\u0000Materials & Methods: This review is based on ample literature search of Medline, the Cochrane Database of Systemic Reviews, and citation lists of relevant publications.\u0000Discussion: COVID-19 pandemic has caused a variety of health problems including mental health issues. Initial panic about the completely unknown (Novel) virus plaguing the world was soon joined by an array of mental health problems like anxiety, depression, combined anxiety and depression, traumatic stress etc. Amidst the chaos of unpredictability, mortality, overstretched health facilities etc. we often downplay the importance of paying attention to the mental side of the disease spectrum. As a result, outcomes like child abuse, domestic violence and suicide can increase.\u0000Conclusion: It is of utmost importance to educate mass people about the coping strategies to go through this hard time, to ensure proper news sharing, to screen people who are at risk of developing mental health problems and to provide support to those who are in need. Local and International consensus guideline should be planned to deal with this issue.\u0000Medicine Today 2021 Vol.33(2): 169-171","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90339093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Outcome and Operative Findings with Ectopic Pregnancy at Tertiary Medical College & Hospital","authors":"F. Sultana, G. Ara, Sayma Afroz, Rokshana Parvin Nupur, Mashah Binte Amin","doi":"10.3329/medtoday.v33i2.56065","DOIUrl":"https://doi.org/10.3329/medtoday.v33i2.56065","url":null,"abstract":"Introduction: An ectopic pregnancy is an emergency condition worldwide now a days which defined as a pregnancy that progresses after implantation of the blastocyst anywhere other than the endometrium lining the uterine cavity. Objective: In this study our main goal is to identify clinical outcome and operative situation in patients.\u0000Materials and Methods: This descriptive study was performed from January 2015 to December, 2018 at tertiary medical College & Hospital. During the study 200 patients were evaluated and data was extracted from socio-demographic, menstrual, obstetric and clinical history of the patients.\u0000Results: most of the patients belong to 30 years (19.7%) age group and history of pelvic infection (26.26%), induced abortion (17.4%), previous MR (16.26%) and sub fertility (11.25%) were common risk factor in ectopic pregnancy found in the study. Also majority of the patients faced laparotomy followed by right sided salphinogectomy (40.40%) which was the most common operation.\u0000Conclusion: quick diagnosis, classifying of risk factors and timely intervention in the form of surgical treatment is necessary for reduction mortality rate in ectopic pregnancy.\u0000Medicine Today 2021 Vol.33(2): 160-164","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"16 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89925561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and Safety of Gabapentine and Duloxetine in Diabetic Peripheral Neuropathic Pain","authors":"Hussain Ahmad, K. H. Rahman, Mifta Chowdhury, Monharul Islam Bhuiya, Nurjahan Ferdous, Md Abu Nayeem Chowdhury","doi":"10.3329/medtoday.v33i2.56054","DOIUrl":"https://doi.org/10.3329/medtoday.v33i2.56054","url":null,"abstract":"Introduction: Diabetic peripheral neuropathy (DPNP) is not uncommon now a days. As the pathophysiology is not completely understood, symptoms relief is still the main goal of treatment. Gabapentine and Duloxetine are being using around the world for this purpose. But clinical data regarding its efficacy and safety are not sufficiently available.\u0000Materials and Methods: This prospective comparative clinical study conducted in Sylhet MAG Osmani Medical College and Sylhet Diabetic Hospital, Bangladesh from January 2013 to December 2013. Diagnosis of DPNP confirmed by Michigan Neuropathy Screening Instrument (MNSI) and Douleur Neuropathic en-4 (DN4). Patients were treated by Gabapentine (Group-A) and Duloxetine (Group-B); and followed up at 4th, 8th and 12th week of treatment using 11-point numerical pain rating scale (NRS), clinical global impression of change (CGIC) score and patient’s global impression of change (PGIC) score.\u0000Results: A total of 72 patients with DPNP were recruited. Final comparison was done in 64 patients – 33 in Group-A and 31 in Group-B. Changes in NRS (p = <0.001), CGIC (p = <0.001) and PGIC (p = <0.001) were statistically significant during the course of treatment. However, inter-group variation of NRS, CGIC and PGIC were not statistically significant at the beginning and 4th, 8th and 12th week of treatment. Insignificant adverse effects were noted between the groups in this study except constipation (p = 0.022) and nausea-vomiting (p = 0.01) of Duloxetine taking group.\u0000Conclusion: Gabapentine and Duloxetine are equally effective in the treatment of DPNP with good safety profile.\u0000Medicine Today 2021 Vol.33(2): 108-113","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87226390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome of Preterm Labour in SSMC Mitford Hospital, Dhaka.","authors":"Mamata Manjari, Lipika Ghosh, R. Khatun, Jahanara Akter, Md Mohim Ibn Sina, M. M. Rahman","doi":"10.3329/medtoday.v33i2.56061","DOIUrl":"https://doi.org/10.3329/medtoday.v33i2.56061","url":null,"abstract":"Introduction: : Preterm birth as a consequence of preterm labour is the major clinical problem associated with perinatal mortality, serious neonatal morbidity and moderate to severe childhood disability and two-thirds of all perinatal deaths. Moreover, preterm labour comprises a large number of low birth weight babies. Global incidence of preterm labour is 5-10% of all births. The aim of this study was to determine the clinical profile and to find out pregnancy outcomes of preterm labour.\u0000Materials & Methods: This cross-sectional study was conducted in Sir Salimullah Medical College Mitford Hospital, Dhaka from January 2005 to December 2005. A total 103 gravid women who got admitted with established premature labour pain were included as study patients. Preterm labour associated with severe pre-eclampsia, eclampsia, antepartum haemorrhage and intrauterine fetal death were excluded. Data were collected in a pre-designed questionnaire and analyzed by SPSS software.\u0000Results: Incidence of preterm labour was found 6.3%. Among maternal morbidities, puerperal sepsis found to be highest (14.56%) followed by UTI (7.77%), PPH (6.80%), wound infection (5.83%) and retained placenta (3.88%). This study found perinatal mortality 32.0% and morbidity 49.5% of which RDS contributed highest (24.27%) followed by neonatal jaundice (11.65%), septicemia (8.73%), neonatal convulsion (2.91%) and umbilical sepsis (1.94%).\u0000Conclusion: Preterm labor followed by preterm birth significantly contributes to maternal morbidity and perinatal morbidity and mortality.\u0000Medicine Today 2021 Vol.33(2): 143-146","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84162161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colonoscopic Yield in Patients with Lower Gastrointestinal Bleeding – A Study of 309 Cases","authors":"M. Saha, Md. Anisur Rahman, M. Zakaria, Musammat Aklima Akter Hely, N. Aktar, Habib Ullah Abir","doi":"10.3329/medtoday.v33i2.56056","DOIUrl":"https://doi.org/10.3329/medtoday.v33i2.56056","url":null,"abstract":"Introduction: This retrospective study was done to see colonoscopic yields in patients presenting with lower gastrointestinal bleeding.\u0000Materials & Methods: Reports of patients undergoing colonoscopy due to bleeding per rectum were retrieved from endoscopy records. Patients’ particulars and colonoscopic findings were recorded in a data sheet. Analysis was done using SPSS 20 version.\u0000Results: A total of 309 patients (male 211 (68.3%) and female 98 (31.7) with mean age 40.3 years %)) were included in this study. According to colonoscopic yield, causes of LGIB were haemorrhoids 137 (44.33% ), rectal and colonic growth 58(18.77% ) rectal and colonic polyps 54 (17.47% ), anal fissure 38 (12.29% ), proctitis 18 (5.82%), colitis 18(5.82%), ileal ulcer and ileitis 34(11.0%). Colorectal growth was more common among patients age 26 to 60years. Among male rectal growth was slightly higher than female.\u0000Conclusion: Lower gastrointestinal bleeding is more common among males. Commonest cause of LGIB are internal haemorrhoids, rectal growth, rectal and colonic polyps and anal fissure. Colorectal neoplasm, proctitis, colitis and ileal inflammation and ulcers constitute small part.\u0000Medicine Today 2021 Vol.33(2): 120-122","PeriodicalId":39348,"journal":{"name":"Medicine Today","volume":"216 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85883648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}