Nicholas Looby, Cole D Tessendorf, Jack Hagen, Michelle Looby, Benjamin Liscano
{"title":"Recurrent Venous Thromboembolism in a Young Adult: A Case Report and Comprehensive Review of Diagnostic Approaches.","authors":"Nicholas Looby, Cole D Tessendorf, Jack Hagen, Michelle Looby, Benjamin Liscano","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Primary lung adenocarcinoma is a rare but critical diagnosis in young adults, often presenting with atypical symptoms. We report the case of a 29-year-old male with no significant medical history who initially presented with deep vein thrombosis (DVT) and recurrent pulmonary emboli (PE) despite appropriate anticoagulation. Further workup ultimately revealed metastatic lung adenocarcinoma, diagnosed post-mortem. This case underscores the importance of considering occult malignancy in young patients with unprovoked or recurrent venous thromboembolism. Early recognition of underlying cancer in such atypical presentations may facilitate earlier diagnosis and intervention, potentially improving patient outcomes.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 8","pages":"367-372"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prenatal Diagnosis of Placental Mesenchymal Dysplasia and Its Association with Hepatic Mesenchymal Hamartoma in Beckwith-Wiedemann Syndrome: A Case Report.","authors":"Haley S Jerman, Rachel L Rodel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Placental mesenchymal dysplasia (PMD) and hepatic mesenchymal hamartomas are rare diseases associated with Beckwith-Wiedemann Syndrome (BWS). We present the case of a 22-year-old diagnosed with PMD at 24 weeks gestation who required emergent delivery secondary to fetal distress and preeclampsia at 30 weeks' gestation. The neonate was diagnosed with a hepatic mesenchymal hamartoma following delivery. While genetic testing returned negative, a clinical diagnosis was made for BWS due to persistent hypoglycemic episodes, left lower extremity hyperplasia, an umbilical hernia, nephromegaly, bilateral ear creases, and periorbital creases. This case demonstrates that PMD may be the only prenatal indicator of BWS.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 8","pages":"342-344"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Polyarteritis Nodosa with Concurrent CMV Infection: A Case Report and Brief Literature Review.","authors":"Lauren Schild, Matthew Schaffer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A previously healthy 36-year-old male presented to the ED with a six-week history of severe migratory abdominal pain, nightly fevers, fatigue, and weight loss. Labs showed elevated LFTs, CRP, D-dimer, and lymphocytosis along with positive serology for cytomegalovirus (IgM, IgG, DNA). Abdominal CT showed a superior mesenteric venous thrombosis, portal mesenteric venous thrombosis, and multiple splenic infarcts. Diagnostic angiography revealed numerous arterial microaneurysms consistent with polyarteritis nodosa. CMV infection is typically self-limited with complete recovery within days to weeks and in exceedingly rare cases has been reported to cause venous thromboses and splenic infarctions. Polyarteritis nodosa is an ANCA-negative necrotizing vasculitis of medium muscular arteries that typically presents with systemic symptoms and can affect any organ but typically spare the lungs.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 8","pages":"362-364"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sena Uzunlar, Alexander Haitham Turaihi, Hassan Turaihi
{"title":"Endoscopic Treatment of Iatrogenic Colon Perforation: Literature Review and Case Report.","authors":"Sena Uzunlar, Alexander Haitham Turaihi, Hassan Turaihi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Colonoscopic perforation is a severe but rare complication of lower gastrointestinal endoscopies, linked to high morbidity and mortality rates. Iatrogenic perforation during colonoscopy can lead to serious outcomes including extended hospital stays, need for surgical intervention, intra-abdominal sepsis, or death. While perforations have traditionally required surgical or interventional radiology management, use of over-the-scope clipping has offered the option of endoscopic management. Herein we report the case of a 79-year-old woman who presented with concern for colonic perforation after endoscopic polypectomy. Colonic perforation was detected at a follow up colonoscopy. Further investigation with CT revealed findings of perforation with pneumoperitoneum. Repeat colonoscopy was performed revealing the perforation in the distal colon. During the procedure, hemostatic over-the-scope clips were placed, and the defect was successfully closed. This paper aims to highlight the incidence of perforation during colonoscopy and to discuss the role endoscopic management in bowel perforation.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 8","pages":"353-355"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alyssa L Reinschmidt, Kianna Thelen, Samantha Halverson, Karah White, Marcus L Frohm
{"title":"The Development of Malignant Melanoma Concurrent to Encorafenib and Cetuximab Therapy for Gastrointestinal Cancer With Neuroendocrine Features.","authors":"Alyssa L Reinschmidt, Kianna Thelen, Samantha Halverson, Karah White, Marcus L Frohm","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>BRAF inhibitors, among other targeted therapies, have transformed the treatment of many cancers in recent years. While cutaneous malignancies are a known adverse effect of BRAF inhibitors, the following case description highlights the importance of regularly monitoring patients on these therapies for new or changing skin lesions. A female in her 70s presented to the dermatology clinic with the sudden development of several new, dark nevi one month after the initiation of encorafenib with cetuximab for neuroendocrine carcinoma. Biopsy results were positive for a superficial spreading melanoma and a separate lesion demonstrating severe histologic atypia. Procedural dermatology performed a complete excision of both lesions.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 8","pages":"357-360"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sena Uzunlar, Alexander Haitham Turaihi, Hassan Turaihi
{"title":"Anastomotic Leak of Colon Successfully Treated With Double Pig Tail Stent Placed Endoscopically: Literature Review and Case Report.","authors":"Sena Uzunlar, Alexander Haitham Turaihi, Hassan Turaihi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Anastomotic leakage after colorectal surgery is a serious complication , leading to higher morbidity and mortality, permanent stoma formation, and cancer recurrence. Management of anastomotic leaks is patient-specific and surgical management is dictated by the degree of contamination, inflammation, and patient risk factors. Internal drainage with double pigtail stents - initially used for managing leaks after bariatric surgery - has recently been applied to anastomotic leaks following resection of colorectal malignancies. Herein we report the case of a 65-year-old male with a history of sigmoid resection and colosostomy with subsequent ostomy takedown who presented for follow-up. Imaging at this visit showed concern for possible anastomotic leak at the ostomy takedown site. Further endoscopic investigation revealed a small area of anastomotic dehiscence which was therapeutically addressed with stent placement. The patient later presented with concerns of stent migration confirmed with imaging. A larger caliber secondary stent was then successfully placed, and placement and therapeutic effect were confirmed at follow-up. This paper aims to highlight the role of endoscopic management of colorectal anastomotic leak.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 8","pages":"347-350"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mission Impossible: Fighting Burnout.","authors":"Alan Sazama","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 7","pages":"290-291"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aorto-Atrial Fistula Case Report with Discussion on Gerbode Defect.","authors":"Owen Alvine, Joshua Mohs, Samuel Jensen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This case report describes a 62-year-old female with a history of heart failure with preserved ejection fraction (HFpEF) who presented to the emergency department with heart failure exacerbation. She was initially diagnosed with bilateral pleural effusions and treated with thoracentesis and diuretics. When follow-up indicated a lack of improvement, an ischemic workup was ordered. A transesophageal echocardiogram (TEE) revealed an abnormal connection between the right atrium and proximal aorta (aorto-atrial fistula), which was promptly fixed with surgical patching. This report also discusses the Gerbode defect, an abnormal congenital or acquired connection between the left ventricle and right atrium. Both conditions can significantly impact patients undergoing anesthesia. Further research on these abnormalities is essential to prevent poor outcomes.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 7","pages":"295-297"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicholas Looby, Cole D Tessendorf, Jack Hagen, Michelle Looby, Jenny Guido
{"title":"A Potential Unrecognized Risk for Acute Hepatotoxicity: A Case Report of Fulminant Liver Failure Following Recent Initiation of Allopurinol and Colchicine.","authors":"Nicholas Looby, Cole D Tessendorf, Jack Hagen, Michelle Looby, Jenny Guido","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Drug-induced liver injury (DILI) is a leading cause of acute liver failure in the U.S., though allopurinol and colchicine have not been widely associated with fulminant hepatic failure. We present the case of a male in his 50s with chronic kidney disease (CKD) stage III who developed rapid hepatic decompensation shortly after starting allopurinol and colchicine for gout. Within days, he experienced worsening liver function, renal failure, and respiratory distress, ultimately progressing to multiorgan failure and death within 24 hours of hospital admission. A 6 cm esophageal mass was incidentally found on imaging, though its significance remains unclear. Given the temporal relationship between drug initiation and fulminant hepatic failure, this case raises concerns regarding the potential hepatotoxicity of allopurinol and colchicine, particularly in patients with preexisting renal impairment. Increased awareness and early liver function monitoring may be warranted in high-risk patients starting these medications.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 7","pages":"304-309"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Narysse Nicolet, Tiffany Bender, Andrew L Guymon, Lindsey A Kroboth, Cole Tessendorf, Sena Uzunlar, J S Vassar, Suzanne Reuter
{"title":"Medicaid in South Dakota Since Expansion.","authors":"Narysse Nicolet, Tiffany Bender, Andrew L Guymon, Lindsey A Kroboth, Cole Tessendorf, Sena Uzunlar, J S Vassar, Suzanne Reuter","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 2023, South Dakota expanded the Medicaid program, providing health coverage to an additional 29,500 residents who were previously ineligible. Prior to expansion, Medicaid eligibility was limited leaving many South Dakotans without affordable health insurance. This gap in care contributed to significant disparities in healthcare access and outcomes across the state. Medicaid expansion was initially proposed under Senate Bill 186 and later passed during state elections under Amendment D in 2022. The rollout of the expansion program has faced challenges since its initiation with lower enrollment than expected, potentially due to less marketing and an outdated application system. Further the COVID \"churning\" effect, where thousands of individuals were disenrolled due the cessation of COVID-19 emergency protections, occurred in the spring before the Medicaid expansion start date of July 1, 2023, leading to confusion for many enrollees. Despite these challenges, Medicaid expansion has already provided crucial healthcare access to vulnerable populations, including Native American, Black, Hispanic, and Asian communities. However, the recent passing of work requirements under Amendment F, could impact the future of the program. As South Dakota continues to navigate the complexities of Medicaid expansion, ongoing evaluation will be crucial in ensuring the state maximizes the potential of the program.</p>","PeriodicalId":39219,"journal":{"name":"South Dakota medicine : the journal of the South Dakota State Medical Association","volume":"78 7","pages":"299-302"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}