Biologie Aujourd''hui最新文献

{"title":"[Treatment of lupus nephritis].","authors":"Frédéric A Houssiau","doi":"10.1051/jbio/2024006","DOIUrl":"https://doi.org/10.1051/jbio/2024006","url":null,"abstract":"<p><p>Lupus nephritis remains the most frequent severe complication of systemic lupus erythematosus, leading to chronic renal impairment in 20 to 25% of cases. Current treatment is based on the combined use of immunosuppressive treatment and targeted biotherapies to optimize the chances of promptly obtaining and maintaining a complete renal response over the long term. The author discusses these recent advances.</p>","PeriodicalId":39068,"journal":{"name":"Biologie Aujourd''hui","volume":"218 1-2","pages":"25-31"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141617321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COMPTE RENDU DE L’ASSEMBLÉE GÉNÉRALE DU 5 FEVRIER 2024.","authors":"","doi":"10.1051/jbio/2024008","DOIUrl":"https://doi.org/10.1051/jbio/2024008","url":null,"abstract":"","PeriodicalId":39068,"journal":{"name":"Biologie Aujourd''hui","volume":"218 1-2","pages":"73-82"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141617322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Allelopathy: chemical communication between plants].","authors":"Oumayma Mhamdi, Sophie Jasinski, Alexandre de Saint Germain","doi":"10.1051/jbio/2024017","DOIUrl":"https://doi.org/10.1051/jbio/2024017","url":null,"abstract":"<p><p>Today, weed control in agricultural systems is largely based on the use of synthetic pesticides. However, the use of these compounds is increasingly controversial among farmers and consumers, who point to their harmful properties for human health and the environment. In this context, the development of eco-friendly agricultural approaches and practices is becoming essential, and allelopathy represents a promising solution. Allelopathy is the process by which plants release chemical compounds into the environment that alter the development of neighbouring plants. This process has been described since antiquity, but it was not until the 20^th century that the first mechanisms were described and a definition given. Allelopathic compounds are mainly specialised metabolites belonging to three main classes: phenolic compounds, terpenoids and nitrogen containing compounds. They are generally specific to a botanical family or even a plant species. Depending on their chemical nature and the site of biosynthesis, they are released into the environment by volatilisation, leaching, exudation or degradation of plant tissues. The synthesis of these compounds is influenced by biotic and abiotic environmental factors. Allelopathic compounds can affect various plant physiological processes such as photosynthesis, mitochondrial activity, cell division and elongation, membrane transport and certain enzymatic activities. Agricultural practices such as crop rotation, intercropping and mulching already exploit the allelopathic properties of plants. Current research aims to gain a deeper understanding of the molecular and biochemical mechanisms of allelopathy by identifying the genes and metabolites involved in this process. Such knowledge improvements will allow the development of innovative and ecological agricultural approaches based on allelopathy to optimise weed management and thus reduce the use of chemical products, while preserving biodiversity within agro-ecosystems.</p>","PeriodicalId":39068,"journal":{"name":"Biologie Aujourd''hui","volume":"218 3-4","pages":"145-164"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Exploring protein degradation pathways as therapeutic innovations].","authors":"Marie Cornu, Thomas Lemaitre, Florian Schwalen, Charline Kieffer, Anne Sophie Voisin-Chiret","doi":"10.1051/jbio/2024010","DOIUrl":"https://doi.org/10.1051/jbio/2024010","url":null,"abstract":"<p><p>The disruption of proteostasis provides a favourable context for the emergence of therapeutic innovations, in particular by exploiting technologies such as the PROTAC (Proteolysis Targeting Chimera) approach. These technologies aim to selectively target proteins involved in various diseases, including cancer and neurodegenerative diseases, by inducing their specific degradation via the ubiquitin-proteasome system. The PROTAC approach opens new opportunities for restoring altered protein homeostasis and modulating the pathological consequences of proteostasis deregulation. In addition, by targeting proteins that are resistant to conventional therapeutic approaches, this new strategy offers a hope of treatment. By degrading target proteins, regardless of their structure or of mutations, the PROTAC approach opens the way to reaching previously inaccessible targets and reducing resistance to treatment.</p>","PeriodicalId":39068,"journal":{"name":"Biologie Aujourd''hui","volume":"218 3-4","pages":"105-113"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The role of volatile organic compounds in plant-insect communication].","authors":"Nicolas Montagné","doi":"10.1051/jbio/2024016","DOIUrl":"https://doi.org/10.1051/jbio/2024016","url":null,"abstract":"<p><p>Insects and flowering plants are the most abundant and diverse multicellular organisms on Earth, accounting for 75% of known species. Their evolution has been largely interdependent since the so-called Angiosperm Terrestrial Revolution (100-50 Mya), when the explosion of plant diversity stimulated the evolution of pollinating and herbivorous insects. Plant-insect interactions rely heavily on chemical communication via volatile organic compounds (VOCs). These molecules are synthesised by the secondary metabolism of plants through various pathways and include terpenes, benzenoids and aliphatic compounds. As of today, more than 1,700 of these VOCs have notably been identified in flowers. Plants use these molecules to attract pollinators or repel herbivorous insects. VOCs also act as chemical signals for insects, helping them to find food or egg-laying sites. Chemical communication has thus played an important role in the evolutionary history of insects and flowering plants. Tritrophic interactions are a fascinating example of VOC-driven communication. When plants are attacked by herbivores, they emit herbivore-induced volatiles, such as green leaf volatiles and specific terpenes. These signals attract predators or parasitoids of the herbivores, acting as a chemical distress call. For example, parasitoid wasps can identify plants that have been attacked by their host herbivores, even in the absence of the herbivores themselves, thanks to the plant's odour profile. But herbivore-induced volatiles also affect the herbivores themselves. Female moths, for example, use these olfactory cues to avoid laying eggs on plants that have already been attacked. Insects detect VOCs using highly sensitive odorant receptors on their antennae. Herbivorous insects, such as the model moth species S. littoralis, have receptors specific for floral VOCs and herbivore-induced volatiles. Current research aims to understand how the evolution of these receptors has contributed to the adaptation of insects to plant volatiles. In moths, receptors for benzenoids appear to be more ancient and conserved, whereas receptors for terpenes and aliphatic molecules show more recent diversification in response to plant evolution. Research into plant-insect communication also opens up avenues for sustainable agriculture, as VOCs can be used to attract natural pest predators or deter herbivores, reducing the need for chemical pesticides.</p>","PeriodicalId":39068,"journal":{"name":"Biologie Aujourd''hui","volume":"218 3-4","pages":"141-144"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Thousands of years of human-dog relationship].","authors":"Morgane Ollivier","doi":"10.1051/jbio/2024011","DOIUrl":"https://doi.org/10.1051/jbio/2024011","url":null,"abstract":"<p><p>During recent years, much progress has been made in understanding the origin and evolution of the dog. Thanks to the collaboration between zooarchaeology, genomics and paleogenetics, researchers were able to hypothesize scenarios regarding the origins of the canine lineages present in Europe at the end of the Pleistocene and the beginning of the Holocene. Research has also shown a correlation between human and canine migration across time and space, highlighting a strong relationship between man and his best friend. This proximity between the two species is also illustrated by the adaptation of this species to anthropogenic selective pressures, particularly in parallel with cultural transitions. Although the history of this species still requires much exploration to be fully understood, these results provide new theoretical bases for understanding the interplay between humans and dogs.</p>","PeriodicalId":39068,"journal":{"name":"Biologie Aujourd''hui","volume":"218 3-4","pages":"115-127"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Phytoplankton population dynamics along the Casablanca - El Jadida Atlantic coast].","authors":"Soumia Tahraoui, Btissam Ennaffah, Steve L Morton, Fatima Souilmi, Karima Chaira, Requia Sagou, Abdeltif Reani, Brahim Sabour","doi":"10.1051/jbio/2023037","DOIUrl":"https://doi.org/10.1051/jbio/2023037","url":null,"abstract":"<p><p>Our taxonomic study from March 2014 to November 2015 along the atlantic coast between Casablanca and El Jadida revealed that phytoplanktonic structure is mainly represented by Diatoms (Bacillariophyceae), Dinoflagellates (Dinophyceae), Silicoflagellates (Dictyophyceae) and Euglenophyceae with a clear dominance of Diatoms and Dinoflagellates. A total of 101 taxa of planktonic algae have been identified revealing a relatively diversified taxocenosis. In terms of respective diversity, the Diatoms are represented by 62 taxa (61.4%), the Dinoflagellates by 36 taxa (35.6%) whereas the other two groups of Silicoflagellates and Euglenophyceae are only represented by 3 species (3.0%). Regarding potentially toxic species, more than fifteen taxa have been identified, most of which were Dinoflagellates and Diatoms (Pseudo-nitzschia australis and Pseudo-nitzschia cuspidata). The total phytoplankton densities exhibited great spatial and temporal variations as shown by analyses of diversity (H') and equitability (E) indices at the different coast sites investigated throughout the 2014-2015 years. Massive proliferation of some toxic species (e.g. Pseudo-nitzschia australis and Pseudo-nitzschia cuspidata, Lingulodinium polyedrum, Karenia mikimotoi) was also noticed. In addition, our study revealed the presence of opportunistic species (e.g. Eutreptiella, Thalassiosira, Prorocentrum scutellum) and of the new ectoparasite Dinoflagellate Amyloodinium ocellatum for the first time in Morocco. The detection of such diversity of toxic species, sometimes with alarming concentrations, should prompt the competent authorities to broaden the spectrum and frequency of biomonitoring to uncontrolled seafood harvesting sites.</p>","PeriodicalId":39068,"journal":{"name":"Biologie Aujourd''hui","volume":"218 1-2","pages":"63-72"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141617316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Marine trophic and socio-ecological networks under pressure: study of the cumulative impact of climate change and offshore wind farm development].","authors":"Nathalie Niquil, Aurore Raoux, Maud Thermes, Rhoda Fofack-Garcia, Quentin Noguès","doi":"10.1051/jbio/2024012","DOIUrl":"https://doi.org/10.1051/jbio/2024012","url":null,"abstract":"<p><p>In the anthropocene era, one of the greatest challenges facing trophic modeling applied to the marine environment is its ability to couple the multiple effects of both climate change and local anthropogenic activities, notably the development of offshore wind farms. The major challenge is to create scenarios to characterize their cumulative effects on the functioning of the entire socio-ecological system, in order to propose appropriate management plans. Although modeling cumulative impact on socio-ecological networks is not yet widely used, data reported in the present review article show that the relevance of this approach could be established in the context of offshore wind power. Two modeling procedures are herein described: quantitative mathematical modelling to simulate the effect of two simultaneous pressures on food network properties, and qualitative modelling, which can be based on a participatory approach to more finely characterize feedback loops between governance and ecological systems. These two quantitative and qualitative scenarios modeling methods, based on interaction network analyses, were applied to the future Courseulles-sur-Mer offshore wind farm (eastern Channel), and to the Groix-Belle-Ile pilot wind farm (Atlantic). Finally, we present a research perspective, based on the Sato-Umi concept, which focuses on modeling frameworks combining ecosystem network evolution scenarios and an increased capacity for collective action.</p>","PeriodicalId":39068,"journal":{"name":"Biologie Aujourd''hui","volume":"218 3-4","pages":"99-103"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Collective memory and social memory: contributions of sociology to a general theory of memory].","authors":"Jean-François Orianne","doi":"10.1051/jbio/2023003","DOIUrl":"https://doi.org/10.1051/jbio/2023003","url":null,"abstract":"Is a general theory of memory possible? What contribution can sociology make to this vast scientific project? Two original contributions are presented and discussed in this article: (1) the concept of collective memory (Maurice Halbwachs); (2) the concept of social memory (Niklas Luhmann). The author proposes some important theoretical clarifications. First, memory is neither a stock nor a collection (of past states or events) but rather a continuous operation of sorting between remembering and forgetting. Secondly, collective memory is not social memory: indeed, the former is a specific operation of psychic systems whereas the latter is an operation of communication, specific to social systems. In the particular case of the attacks of November 13, 2015 in Paris, the author shows the function of social memory that the mass media system fulfills and how these operations of filtering meaning condition the construction of traumatic memories.","PeriodicalId":39068,"journal":{"name":"Biologie Aujourd''hui","volume":"217 1-2","pages":"65-72"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9807891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The Programme 13-Novembre between individual memory and collective memory].","authors":"Francis Eustache,&nbsp;Denis Peschanski","doi":"10.1051/jbio/2023016","DOIUrl":"https://doi.org/10.1051/jbio/2023016","url":null,"abstract":"<p><p>The purpose of this article is to present the evolution of scientific work on human memory from the end of the 19th century. The work of experimental psychology and neuropsychology first dominated the scientific scene. Research in the humanities and social sciences was established in the interwar period, but without any real interaction with psychology and neurosciences. We recall the most emblematic historical works of two distinct visions of memory: those of the experimental psychologist Hermann Ebbinghaus who measured memory, on himself, from lists of meaningless syllables, and those of the sociologist Maurice Halbwachs for whom any act of memory is a social act. This disciplinary closure persisted until the end of the 20th century. A real social shift has taken place since the 2000s, with a desire to studying and understanding the interactions between individual and collective memories. In this article, the authors argue for the emergence of \"sciences of memory\" based on dialectic and transdisciplinarity. They draw on the Programme 13-Novembre that is emblematic of this evolution. The Programme 13-Novembre has seized upon a diversity of research tools on memory by applying them to a traumatic event in French society: the attacks of 13 November 2015 in Paris and its immediate suburbs. Its genesis, its overall architecture and several of its components are presented here, as well as a few results already published. In addition to its theoretical scope, this work has many possible applications, particularly in the understanding and management of various pathologies, post-traumatic stress disorder being the most demonstrative in this respect.</p>","PeriodicalId":39068,"journal":{"name":"Biologie Aujourd''hui","volume":"217 1-2","pages":"39-48"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9807892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}