Daniel Giaretta Fangueiro, D. Garib, Ana Claudia Ferreira de Castro Conti, Lucila Largura
{"title":"Evaluation of facial pleasantness in patients with complete and unilateral cleft lip and palate rehabilitated and submitted to orofacial harmonization","authors":"Daniel Giaretta Fangueiro, D. Garib, Ana Claudia Ferreira de Castro Conti, Lucila Largura","doi":"10.1590/2177-6709.29.1.e2423115.oar","DOIUrl":"https://doi.org/10.1590/2177-6709.29.1.e2423115.oar","url":null,"abstract":"ABSTRACT Objective: The objective of the present prospective case control study was to evaluate the facial pleasantness of patients with complete and unilateral cleft lip and palate at the end of interdisciplinary rehabilitation, submitted to facial fillers based on hyaluronic acid. Methods: The study group consisted of 18 individuals with complete unilateral cleft lip and palate, aged between 18 and 40 years (mean age 29 years) of both sexes. The patients presented a concave profile with mild to moderate maxillary deficiency, with completed orthodontic treatment and conducted by means of dentoalveolar compensations without orthognathic surgery. Participants underwent facial filling procedures with hyaluronic acid (HA) in the midface, inserted by a single operator. Standard photographs in frontal norm at rest, right profile at rest, and left profile at rest were obtained from each patient at the following operative times: (T1) pre-filler and (T2) and one-month post-filler. The photographs in T1 and T2 were randomly placed on a page of a virtual album. A 5-point Likert scale was used to assess facial pleasantness. The photographs were evaluated by two groups of evaluators consisting of 18 individuals with cleft lip and palate (CLPG=18) and 18 orthodontists with experience in the treatment of clefts (OG=18). For comparison between phases T1 and T2, and between evaluators with orofacial clefts and orthodontists, the Wilcoxon test was used (p<0,05). Results: People with cleft lip and palate rated their face as more pleasant after the midface filling procedure. In the perception of the orthodontists, on the other hand, the facial pleasantness remained similar after the facial filling procedure. Conclusions: The filling of the middle third of the face in patients with cleft lip and palate treated without orthognathic surgery increased the pleasantness of the face in the opinion of laypeople with cleft lip and palate.","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"40 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140367527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melany Clarissa Gámez Medina, Cibelle Cristina Oliveira Dos Santos, Beatriz Oliveira Lima, Marina Bosi Ferreira, David Normando
{"title":"Impact of fixed orthodontic retainers on oral health-related quality of life: a longitudinal prospective study.","authors":"Melany Clarissa Gámez Medina, Cibelle Cristina Oliveira Dos Santos, Beatriz Oliveira Lima, Marina Bosi Ferreira, David Normando","doi":"10.1590/2177-6709.29.1.e242317.oar","DOIUrl":"10.1590/2177-6709.29.1.e242317.oar","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the present study was to assess the impact of orthodontic retainers on oral health-related quality of life (OHRQoL) in the short and long terms after orthodontic treatment.</p><p><strong>Methods: </strong>Data from 45 patients up to three years after orthodontic treatment (T0) were analyzed. Patients were reassessed four years (T1) after T0. OHRQoL was measured using the OHIP-14 (Oral Health Impact Profile-14) questionnaire. The presence of a fixed retainer in the upper and/or lower arches, sex, and age were the predictive variables evaluated at T0 and T1. The occurrence of retainer fracture at T0 was clinically evaluated. Due to the COVID-19 pandemic, clinical examination on T1 was not possible, so the OHIP-14 and the self-perception of changes in teeth position and fracture of retainers were examined using an on-line questionnaire.</p><p><strong>Results: </strong>At the initial examination, the presence of upper retainers had a negative impact on quality of life (p=0.018). The OHIP-14 value increased significantly from T0 to T1 (p=0.014), regardless of the presence of retainers. The fracture or debonding of the retainer reported by the patient was the only variable that had a negative impact on OHRQoL (p=0.05).</p><p><strong>Conclusion: </strong>The use of fixed upper retainers suggests a negative impact on the quality of life of the orthodontic patient after the end of orthodontic treatment. This impact, however, is negligible in the long term, except when associated with fracture or debonding. This study emphasizes the need for continuous follow-up of orthodontic patients during the retention period.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"29 1","pages":"e242317"},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10914318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patricia Nadelman, Eduardo Otero Amaral Vargas, Guido Artemio Marañón-Vásquez, Ana Lúcia Vollú, Matheus Melo Pithon, Amanda Cunha Regal de Castro, Lucianne Cople Maia
{"title":"Occlusion development after premature loss of deciduous anterior teeth: preliminary results of a 24-month prospective cohort study.","authors":"Patricia Nadelman, Eduardo Otero Amaral Vargas, Guido Artemio Marañón-Vásquez, Ana Lúcia Vollú, Matheus Melo Pithon, Amanda Cunha Regal de Castro, Lucianne Cople Maia","doi":"10.1590/2177-6709.29.1.e2423285.oar","DOIUrl":"10.1590/2177-6709.29.1.e2423285.oar","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate occlusion development after premature loss or extraction of deciduous anterior teeth, by means of a prospective cohort study.</p><p><strong>Methods: </strong>Fifteen infants and children aged 1 to 5 years old were longitudinally assessed (with loss or extraction of deciduous anterior teeth [n = 9], and without tooth losses [n = 6]). Photographs and dental casts at the baseline and after 24 months of follow-up were performed. Dental casts were scanned, and linear measurements were made on the digitalized models (missing tooth space, arch perimeter, arch length, arch width, intercanine length and intercanine width). The t-test was used for groups comparisons (α = 0.05).</p><p><strong>Results: </strong>Individuals' mean age at baseline was 2.93 (± 1.18) years. No statistically significant differences were observed in the missing tooth space in the group with tooth loss during the 24 months of follow-up (p > 0.05). Arch perimeter, arch length, arch width, intercanine length and intercanine width did not show differences between the groups (p > 0.05). Qualitative photographic evaluation revealed other changes in the dental arches and occlusion, such as exfoliation and eruption of deciduous teeth, eruption of permanent teeth, self-correction or establishment of malocclusion, among others.</p><p><strong>Conclusion: </strong>The results suggest that the premature loss of deciduous anterior teeth does not affect the perimeter, length and width of the dental arches; however, other alterations that lead to malocclusion could be established.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"29 1","pages":"e2423285"},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10914317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of different palatal expanders with miniscrews in surgically assisted rapid palatal expansion: A non-linear finite element analysis.","authors":"Osman Koç, Nagihan Koç, Helder Baldi Jacob","doi":"10.1590/2177-6709.29.1.e2423195.oar","DOIUrl":"10.1590/2177-6709.29.1.e2423195.oar","url":null,"abstract":"<p><strong>Introduction: </strong>Surgically assisted rapid palatal expansion (SARPE) has been the treatment of choice in subjects presenting skeletally mature sutures.</p><p><strong>Objective: </strong>The purpose of this study was to analyze stress distribution and displacement of the craniofacial and dentoalveolar structures resulting from three types of palatal expanders with surgical assistance using a non-linear finite element analysis.</p><p><strong>Material and methods: </strong>Three different palatal expanders were designed: Model-I (tooth-bone-borne type containing four miniscrews), Model-II (tooth-bone-borne type containing two miniscrews), and Model-III (bone-borne type containing four miniscrews). A Le Fort I osteotomy was performed, and a total of 5.0 mm palatal expansion was simulated. Nonlinear analysis (three theory) method (geometric nonlinear theory, nonlinear contact theory, and nonlinear material methods) was used to evaluate stress and displacement of several craniofacial and dentoalveolar structures.</p><p><strong>Results: </strong>Regardless of the maxillary expander device type, surgically assisted rapid palatal expansion produces greater anterior maxillary expansion than posterior (ANS ranged from 2.675 mm to 3.444 mm, and PNS ranged from 0.522 mm to 1.721 mm); Model-I showed more parallel midpalatal suture opening pattern - PNS/ANS equal to 54%. In regards to ANS, Model-II (1.159 mm) and Model-III (1.000 mm) presented larger downward displacement than Model-I (0.343 mm). PNS displaced anteriorly more than ANS for all devices; Model-III presented the largest amount of forward displacement for PNS (1.147 mm) and ANS (1.064 mm). All three type of expanders showed similar dental displacement, and minimal craniofacial sutures separation. As expected, different maxillary expander designs produce different primary areas and levels of stresses (the bone-borne expander presented minimal stress at the teeth and the tooth-bone-borne expander with two miniscrews presented the highest).</p><p><strong>Conclusions: </strong>Based on this finite element method/finite element analysis, the results showed that different maxillary expander designs produce different primary areas and levels of stresses, minimal displacement of the craniofacial sutures, and different skeletal V-shape expansion.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"29 1","pages":"e2423195"},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10914319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of orthodontic treatment on OHRQoL of adolescents: a longitudinal study.","authors":"Paula Guerino, Fernanda Ruffo Ortiz, Mariana Marquezan, Thiago Machado Ardenghi, Vilmar Antônio Ferrazzo","doi":"10.1590/2177-6709.29.1.e2423136.oar","DOIUrl":"10.1590/2177-6709.29.1.e2423136.oar","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to evaluate the extent to which orthodontic treatment need is perceived by the patients and by the orthodontist, as well as the possible impacts on the OHRQoL (Oral Health-Related Quality of Life) over the course of conventional orthodontic treatment in adolescent patients.</p><p><strong>Methods: </strong>The sample consisted of 55 adolescents. The perception of patients and orthodontists relative to the malocclusion was evaluated by the IOTN (Index of Orthodontic Treatment Need). The OHRQoL was evaluated by the Child-OIDP (Child-Oral Impacts on Daily Performances) questionnaire before the conventional orthodontic appliance was bonded (T0); and at the following time intervals: after one week (T1), one month (T2), three months (T3), six months (T4), and after the end of orthodontic treatment (T5).</p><p><strong>Results: </strong>Adolescents who had large orthodontic treatment needs had a poor OHRQoL, according to their self-perception (p=0.003) and according to the orthodontist's perception (p<0.001), when compared with patients with small and moderate needs. There was statistically significant difference in the OHRQoL between the time intervals T0 and T1 (p=0.021), T2 and T3 (p<0.001), T3 and T4 (p=0.033), and T0 and T5 (p<0.002). At the end of treatment, all evaluated participants reported an improvement in OHRQoL.</p><p><strong>Conclusions: </strong>It was concluded that adolescents and orthodontists agreed with regard to the perception of orthodontic treatment need. In the first week and in the first month of orthodontic treatment, there was a negative impact on the OHRQoL. After three months, an improvement of OHRQoL was detected, which has progressed over time.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"29 1","pages":"e2423136"},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10871072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139742252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isabela Sales Pinheiro, Cleverson Raymundo Sbarzi Guedes, Analina Braga Apolinário, Fernanda Ramos de Faria, Sergio Luiz Mota Júnior, Matheus Melo Phiton, Marcio José da Silva Campos, Robert Willer Farinazzo Vitral
{"title":"Civil liability of orthodontists and aligner manufacturers in the treatment with orthodontic aligners.","authors":"Isabela Sales Pinheiro, Cleverson Raymundo Sbarzi Guedes, Analina Braga Apolinário, Fernanda Ramos de Faria, Sergio Luiz Mota Júnior, Matheus Melo Phiton, Marcio José da Silva Campos, Robert Willer Farinazzo Vitral","doi":"10.1590/2177-6709.29.1.e24spe1","DOIUrl":"10.1590/2177-6709.29.1.e24spe1","url":null,"abstract":"<p><strong>Introduction: </strong>The use of clear aligners as an alternative to fixed orthodontic appliances has become popular due to the aesthetic demands of adult patients seeking orthodontic treatment. However, orthodontists' lack of knowledge about the legal consequences of their activities, and the lack of solid scientific evidence raise concerns regarding civil liability in this type of treatment. Marketing campaigns of manufacturing companies often exaggerate promises of results, and ignore the lack of scientific evidence. Patients, as consumers, are protected by the Consumer Protection Code, whereas orthodontists are considered treatment providers. Therefore, they can be held liable for damage caused to patients, whether by subjective or objective fault.</p><p><strong>Objective: </strong>This article aims to identify the civil responsibilities of orthodontists and aligner manufacturing companies, by means of a literature review, providing basic legal guidance to help professionals protect themselves from possible lawsuits related to treatment with orthodontic aligners.</p><p><strong>Conclusions: </strong>The study highlights the importance of knowledge of legal notions in treatments with orthodontic aligners by orthodontists, who should legally safeguard themselves through individual written contracts, avoiding obligation of results. In addition, in cases of legal claims, it is possible that the manufacturing companies are jointly and severally liable for possible damages claimed by the patient.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"29 1","pages":"e24spe1"},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10871073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139742251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diogo Marques Sapata, Cléverson de Oliveira E Silva, Renata Corrêa Pascotto, Thais Maria Freire Fernandes Poleti, Maristela Sayuri Inoue Arai, Adilson Luiz Ramos
{"title":"Periodontal indexes of two types of 3 x 3 retainers: 0.032-in SS V-loop versus 0.0215-in SS coaxial - a randomized crossover trial.","authors":"Diogo Marques Sapata, Cléverson de Oliveira E Silva, Renata Corrêa Pascotto, Thais Maria Freire Fernandes Poleti, Maristela Sayuri Inoue Arai, Adilson Luiz Ramos","doi":"10.1590/2177-6709.28.6.e2323175.oar","DOIUrl":"10.1590/2177-6709.28.6.e2323175.oar","url":null,"abstract":"<p><strong>Objective: </strong>This randomized crossover trial evaluated periodontal indexes of two types of 3 x 3 retainers (a modified 0.032-in SS V-loop retainer and a conventional 0.0215-in SS coaxial wire retainer) after bonded for six months. Also, bonded failure rate, and a questionnaire about comfort, ease of cleaning and overall preference were recorded.</p><p><strong>Material and methods: </strong>15 patients were enrolled in this study who used both retainers for six months each, having a 15-day wash-out interval between each bonded retainer usage. The following periodontal index were recorded: Plaque Index (PI), Calculus Index (CI) and Gingival Index (GI). Patients answered a questionnaire to assess comfort, ease of cleaning and overall retainer-type preference. Rate of bonding failure was also evaluated.</p><p><strong>Results: </strong>V-Loop retainer showed higher PI (P<0.05) as compared to conventional 0.0215-in coaxial wire retainer. However, CI and GI presented no statistically significant differences between both types of retainers. The conventional 0.0215-in coaxial wire retainer was chosen as the most comfortable (p<0.05), although no statistically significant differences were found for all other questionnaire answers. Bonding failure events were more observed in the 3x3 V-Loop retainer (p<0.002), as compared to the conventional 0.0215-in coaxial retainer.</p><p><strong>Conclusion: </strong>V-Loop retainer showed higher PI (p<0.05), higher bonding failure rate and less comfortable, as compared to conventional 0.0215-in coaxial wire.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"28 6","pages":"e2323175"},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10773445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139418276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Navleen Kaur Bhatia, Vinay Kumar Chugh, Sam Prasanth Shankar, Ritvik Vinay A P, Surjit Singh, Priyawati Moungkhom, Rinkle Sardana
{"title":"Alignment efficiency and three-dimensional assessment of root resorption after alignment with conventional and copper-nickel-titanium archwires: A randomized controlled trial.","authors":"Navleen Kaur Bhatia, Vinay Kumar Chugh, Sam Prasanth Shankar, Ritvik Vinay A P, Surjit Singh, Priyawati Moungkhom, Rinkle Sardana","doi":"10.1590/2177-6709.28.6.e2323177.oar","DOIUrl":"10.1590/2177-6709.28.6.e2323177.oar","url":null,"abstract":"<p><strong>Objective: </strong>To compare alignment efficiency and root resorption between nickel-titanium (NiTi) and copper-nickel-titanium (CuNiTi) archwires after complete alignment in mandibular anterior region.</p><p><strong>Methods: </strong>In this two-arm parallel single-blind randomized controlled trial, forty-four patients with Class I malocclusion with mandibular anterior crowding were recruited form orthodontic clinic of All India Institute of Medical Sciences (Jodhpur, India). Patients were randomly allocated into NiTi and CuNiTi groups, with a 1:1 allocation. Alignment was performed using 0.014-in, 0.016-in, 0.018-in, 0.019x0.025-in archwire sequence in the respective groups, which terminated in 0.019 x 0.025-in stainless-steel working archwire. The primary outcome was alignment efficiency, measured on study models from baseline (T0) to the first, second, third, fourth and fifth-month (T5). Secondary outcome was root resorption, measured from CBCT scans taken at T0 and T5. Mixed-factorial ANOVA was used to compare Little's Irregularity Index (LII). For assessing the proportion of patients with complete alignment at the end of each month, Kaplan-Meier survival curve was built and time to treatment completion was compared between groups using log rank test. Paired t-test was used to assess external apical root resorption (EARR) within groups, whereas independent t-test was used to evaluate LII and EARR between the groups.</p><p><strong>Results: </strong>Twenty-two patients were recruited in each group. One patient was lost to follow-up in the CuNiTi group. No statistically significant differences were observed in alignment efficiency between the groups (p>0.05). Intergroup comparison revealed that the changes in root measurement in three-dimensions were not statistically significant (p>0.05), except for mandibular right central incisor, which showed increased resorption at root apex in NiTi group (p<0.01).</p><p><strong>Conclusion: </strong>The two alignment archwires showed similar rate of alignment at all time points. Root resorption measurement did not differ between the NiTi and CuNiTi groups, except for the mandibular right central incisor, which showed more resorption in NiTi group.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"28 6","pages":"e2323177"},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10773444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139418273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karla Lorene de França Leite, Mariana Leonel Martins, Amanda Souza Nunes Monteiro, Thiago Isidro Vieira, Adílis Kalina Alexandria, Gustavo Miranda Rocha, Andréa Fonseca-Gonçalves, Matheus Melo Pithon, Yuri Wanderley Cavalcanti, Lucianne Cople Maia
{"title":"In-vitro effect of a single application of CPP-ACP pastes and different fluoridated solutions on the prevention of dental caries around orthodontic brackets.","authors":"Karla Lorene de França Leite, Mariana Leonel Martins, Amanda Souza Nunes Monteiro, Thiago Isidro Vieira, Adílis Kalina Alexandria, Gustavo Miranda Rocha, Andréa Fonseca-Gonçalves, Matheus Melo Pithon, Yuri Wanderley Cavalcanti, Lucianne Cople Maia","doi":"10.1590/2177-6709.28.6.e2321383.oar","DOIUrl":"10.1590/2177-6709.28.6.e2321383.oar","url":null,"abstract":"<p><strong>Objective: </strong>To assess the in-vitro effect of single applications of CPP-ACP pastes and different fluoridated solutions on the prevention of dental caries around orthodontic brackets.</p><p><strong>Material and methods: </strong>Tooth/bracket sets (n=65) were immersed in artificial saliva (1h at 37ºC) and randomly subjected to single applications (100µL; 1min) of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP emulsion), CPP-ACP with fluoride (CPP-ACPF emulsion), solutions of titanium tetrafluoride (TiF4) or sodium fluoride (NaF), or no treatment (CG). Multispecies biofilm (5 x 105 CFU/mL) was formed in the presence of 2% sucrose. After 24 h, the pH and the concentration of total soluble fluoride (TSF) were analyzed by culture medium. The presence of active white spot lesions (WSL) evaluated by macroscopic examination and the percent surface mineral loss (%SML) were analyzed. Also, the topography of enamel was detected by analysis of scanning electron microscopy (SEM). The data was assessed by chi-square, Kruskal-Wallis, and Mann-Whitney tests (p < 0.05).</p><p><strong>Results: </strong>Fluoride-containing compounds led to a smaller pH reduction than did CPP-ACP and CG (p<0.05). There was difference in TSF between the groups (p<0.05), denoted as TiF4> NaF > CPP-ACPF > CPP-ACP > CG. Regarding the presence of WSL and %SML, the NaF group obtained lower values (p<0.05), while TiF4 and CPP-ACPF were similar (p>0.05). SEM demonstrated that fluoride-free groups had a larger surface dissolution.</p><p><strong>Conclusion: </strong>Fluoridated groups including solutions and CPP-ACPF were more effective than CPP-ACP in reducing enamel demineralization around orthodontic brackets after a single application.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"28 6","pages":"e2321383"},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10773443/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139418275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roberta Magalhães Miranda, Juliana Lourdes Fernandes, Mariana de Souza Santos, Humberto Jácome-Santos, Roselaine Moreira Coelho Milagres, Henrique Pretti, Lucas Guimarães Abreu, Soraia Macari
{"title":"Influence of risedronate on orthodontic tooth movement in rodents: a systematic review and case report.","authors":"Roberta Magalhães Miranda, Juliana Lourdes Fernandes, Mariana de Souza Santos, Humberto Jácome-Santos, Roselaine Moreira Coelho Milagres, Henrique Pretti, Lucas Guimarães Abreu, Soraia Macari","doi":"10.1590/2177-6709.28.6.e2322280.oar","DOIUrl":"10.1590/2177-6709.28.6.e2322280.oar","url":null,"abstract":"<p><strong>Introduction: </strong>Bisphosphonates have an inhibitory impact on osteoclastic activity, reducing bone resorption. However, the influence of risedronate on tooth movement is not well-defined.</p><p><strong>Objective: </strong>This systematic review assessed the effect of risedronate intake on orthodontic tooth movement. A case report was also provided.</p><p><strong>Methods: </strong>Two independent reviewers searched six databases (PubMed, Web of Science, Ovid, Lilacs, Scopus, and Open Grey). The searches were carried out in April/2020, and an update was set in place in June/2023. Therefore, the searches considered a timeline from the databases' inception date until June/2023, with no publication date and/or language restrictions. The clinical question focused on evaluating the orthodontic tooth movement and relapse movement (Outcome) in animals (Population) exposed to risedronate (Exposure), compared to control groups (Comparison). The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines were applied, and the protocol was registered in PROSPERO (CRD42020168581). The risk of bias was determined using the Systematic Review Centre for Laboratory Animal Experimentation protocol (SYRCLE).</p><p><strong>Results: </strong>Two studies in rats and one in guinea pigs were included in the systematic review. The studies reported a decrease in orthodontic tooth movement, a reduction in the relapse movement, and a reduced number of positive tartrate-resistant acid phosphatase (TRAP) cells, with a significantly reduced number of bone gaps after the administration of risedronate in rats. A case report illustrated the effects of risedronate administration in one patient.</p><p><strong>Conclusion: </strong>Based on the systematic review, risedronate seems to impair orthodontic tooth movement and relapse due to a decrease in bone resorption cells.</p>","PeriodicalId":38720,"journal":{"name":"Dental Press Journal of Orthodontics","volume":"28 6","pages":"e2322280"},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10773446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139418274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}