{"title":"A new model-based ectopic beat correction algorithm for heart rate variability","authors":"M. Brennan, M. Palaniswami, P. Kamen","doi":"10.1109/IEMBS.2001.1018996","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1018996","url":null,"abstract":"We propose a new ectopic beat correction algorithm for Heart Rate Variability (HRV) that is based on the Integral Pulse Frequency Modulation (IPFM) model. The model is used to infer the modulation signal that has generated the beats surrounding the ectopic beat. The ectopic beat is then removed and replaced with a normal beat at the time which least disturbs the rhythm identified with the IPFM model. We test the performance of the technique by removing simulated ectopy from real heart rate data from human subjects using a number of previously published correction techniques as well as our own. We show that our new technique performs significantly better than existing: techniques for low and high levels of ectopy.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114727600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Open ended coaxial line for electrical characterization of human blood","authors":"F. Jaspard, M. Nadi","doi":"10.1109/IEMBS.2001.1017463","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1017463","url":null,"abstract":"An open-ended coaxial line was used for measurement of the complex permittivity of human blood. In dielectric characterization, modelling of the probe is a fundamental step, which permits the relationship between the complex electric admittance and the complex permittivity to be obtained. The electrical equivalent circuit model was investigated and the performances for blood measurement were estimated. In this paper we present the evaluation of a probe configuration as regards the frequency and the permittivity range measurement. The proposed model permits us to obtained result on fresh heparined human blood close to the literature value.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"134 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124444271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Farina, L. Arendt-Nielsen, R. Merletti, T. Graven‐Nielsen
{"title":"A spike triggered averaging technique for high resolution assessment of single motor unit conduction velocity changes during fatiguing voluntary contractions","authors":"D. Farina, L. Arendt-Nielsen, R. Merletti, T. Graven‐Nielsen","doi":"10.1109/IEMBS.2001.1020381","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1020381","url":null,"abstract":"In this paper we propose an improved spike triggered averaging technique for the assessment of control properties and conduction velocity (CV) of single motor units (MUs) during voluntary sub-maximal muscle contractions. The method is based on the detection of multi-channel surface EMG signals (with linear electrode arrays) and intramuscular recorded single MU action potentials (MUAPs). Intramuscular electrodes are inserted taking into account the MU structural properties (innervation zone and tendon locations, length of the fibers), assessed by the linear array surface EMG detection. A technique for intramuscular EMG signal decomposition is used to identify single MUAP trains. The MUAPs obtained from the intramuscular EMG decomposition algorithm are used to trigger and average the multi-channel EMG signals. CV of single averaged surface MUAPs is estimated by the use of advanced signal processing methods based on multi-channel recordings which allow to consistently reduce the variance of CV estimates with respect to traditional two channel delay estimators. The number of averaged potentials can thus be reduced, improving temporal resolution. The technique proposed is tested with recordings from the tibialis anterior muscle of 11 volunteers. It is shown that the method allows the assessment of CV changes (fatigue) of single MUs as small as 0.1 m/s with a limited number of averages (temporal resolution of 1-2 seconds), leading to a consistent improvement with respect to traditional surface EMG spike triggered averaging techniques. The method has potential usefulness in a number of basic and applied research fields.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"161 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124512870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An integrated model of the human cardiopulmonary system","authors":"K. Lu, J. Clark, F. Ghorbel, D. Ware, A. Bidani","doi":"10.1109/IEMBS.2001.1018949","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1018949","url":null,"abstract":"We have developed a mathematical model of the human cardiopulmonary system that is able to simulate the normal functions of the cardiovascular and pulmonary systems, as well as their coupled interactions. Included in the model are descriptions of atrial and ventricular mechanics, the hemodynamics of the systemic and pulmonic circulations, baroreflex control of arterial pressure, airway and lung mechanics, as well as, gas transport at alveolar-capillary membrane. With the suitable parameter set, the integrated cardiopulmonary model yielded pressure, volume and flow waveforms that agree well with published data. In addition, The model demonstrated stability under large amplitude perturbations of the physiological variables, such as Valsalva Maneuver.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"282 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127552031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Domingo, P. Caminal, B. Giraldo, S. Benito, M. Vallverdú, D. Kaplan
{"title":"Respiratory pattern variability analysis based on nonlinear prediction methods","authors":"L. Domingo, P. Caminal, B. Giraldo, S. Benito, M. Vallverdú, D. Kaplan","doi":"10.1109/IEMBS.2001.1020506","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1020506","url":null,"abstract":"The traditional techniques of data analysis are often not sufficient to characterize the complex dynamics of respiration. In this study the respiratory pattern variability at different levels of pressure support ventilation (PSV) has been analyzed using nonlinear prediction methods. These methods use the volume signals generated by the respiratory system in order to construct a model of its dynamics, and then to estimate the deterministic level of the system from the quality of the predictions made with the model. Different methods of prediction evaluation and neighborhood definition have been considered. The incidence of different prediction depths and embedding dimensions have been analyzed. A group of 12 patients on weaning trials from mechanical ventilation have been studied at two different PSV levels. High statistically significant differences have been obtained when comparing the mean prediction error at two different PSV levels (p<0.002) with non-parametric analysis of variance test (Wilcoxon's signed rank test). The embedding dimension needed to model the system dynamics with low prediction error has also presented significant differences (p<0.005) between the complex dynamics of both PSV levels. Therefore, it may be concluded that the respiratory pattern variability depends on the level of pressure support ventilation.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126237147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The comparison of work of breathing methodologies on a patient model","authors":"E. Koumoundouros, J. Santamaria, J. Patterson","doi":"10.1109/IEMBS.2001.1018957","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1018957","url":null,"abstract":"Pressure volume curves were obtained from a surgical patient during the weaning period to determine the inspiratory Work Of Breathing (WOB). The methodologies of Otis (1950, 1977) and Campbell (1958, 1970) were used to derive the work per breath. There were differences recorded by these methods, which are explained with the use of an electrical RLC model of the respiratory system. The patient was spontaneously breathing during the ventilated support period and then breathing through the ET tube during an unsupported stage, just prior to extubation. The inspiratory work derived from: the airway pressures (Wpaw) were 0.23/spl plusmn/0.03 Joules per breath (Jpb) and 0.00 Jpb; transpulmonary pressures were 0.31/spl plusmn/0.04 Jpb and 0.27/spl plusmn/0.08 Jpb; Campbell Diagram were 0.30/spl plusmn/0.06 Jpm and 0.42/spl plusmn/0.14 Jpb; and a simplified Campbell's method (WcampRO) were 0.24 /spl plusmn/0.05 Jpb and 0.33 /spl plusmn/0.13 Jpb, during supported and unsupported periods, respectively. The simplistic approach of Wpaw and WcampRO methods produced work levels that were significantly lower than their standard methods during both phases (p<0.001). Otis methods show a decrease in the levels of work when the work should have increased due to imposed WOB during the unsupported period, as recorded by using Campbell's methods.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126269182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Martínez, J. Millet, J. Chorro, A. Cebrián, M. Arredondo, I. Garcia
{"title":"Medmap: a powerful multichannel ELG recordings analyzer","authors":"A. Martínez, J. Millet, J. Chorro, A. Cebrián, M. Arredondo, I. Garcia","doi":"10.1109/IEMBS.2001.1017211","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1017211","url":null,"abstract":"The study and analysis of multiple recording electrograms (ELG) in experimental models requires dedicated software for their processing. This software must be quick and efficient in manipulating the enormous amounts of recorded data. Furthermore, the software has to be easily extensible in order to introduce new work methods and analysis algorithms adapted to the needs of each research group. This has led us to develop a modular software package in which introduction of new functionalities will not require the development of a new program, resulting in considerable time savings. For development we chose MATLAB, an interactive program with high computing capabilities and powerful tools for graphic visualization. Being a standard platform, developed code can be easily modified and the functionality of any module can be optimised and/or altered at any time, allowing implementation of the latest scientific advances. This software has been conceived for many applications, although in this paper we focus our experience on the study of fibrillatory processes in experimental models where up to 256 electrograms have been recorded using a cardiac electrical system.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126370901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Sheridan, C. Heneghan, M. O'Malley, P. Nolan, W. McNicholas, J. Cullen, P. Nolan
{"title":"Characterization of autonomic nervous influences on PR and RR intervals in the electrocardiogram","authors":"E. Sheridan, C. Heneghan, M. O'Malley, P. Nolan, W. McNicholas, J. Cullen, P. Nolan","doi":"10.1109/IEMBS.2001.1018989","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1018989","url":null,"abstract":"RR and PR intervals were extracted from single channel electrocardiograms in normal human subjects using a wavelet based technique. RR and PR intervals were shown to be correlated with respiration due to common autonomic nervous activation of the sino-atrial and atrio-ventricular nodes. However, evidence for independent autonomic nervous activation of these nodes is also shown based on RR and PR interval spectra, and on RR vs. PR plots.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126433363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Hirao, T. Kuroda, D. Zhang, Y. Kinouchi, H. Yamaguchi, K. Yoshizaki
{"title":"Synchronized measurements of maximum blood flow velocities in carotid, brachial and femoral arteries, and ECG in human posture changes","authors":"Y. Hirao, T. Kuroda, D. Zhang, Y. Kinouchi, H. Yamaguchi, K. Yoshizaki","doi":"10.1109/IEMBS.2001.1018870","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1018870","url":null,"abstract":"In this research, a system has been developed to measure the maximum blood flow velocity simultaneously by an ultrasonic Doppler technique in three arteries during posture changes. As a peculiarity of this system, two semicircular transducers of 15.0 mm in diameter were used as a transmitter to irradiate a wide ultrasonic beam and a receiver. Because, the position relation between an artery and transducers change rapidly during exercise. This system could be applied to a human body changing from a sitting position to an erect position with voluntary muscle constriction. As a result of measurements, the maximum blood flow velocity in femoral artery has been increased significantly in posture changes like the above.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126488964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Tanaka, M. Yoshizawa, T. Yamada, K. Abe, H. Takeda, T. Yambe, S. Nitta
{"title":"In vivo evaluation of pressure head and flow rate estimation in a continuous-flow artificial heart","authors":"A. Tanaka, M. Yoshizawa, T. Yamada, K. Abe, H. Takeda, T. Yambe, S. Nitta","doi":"10.1109/IEMBS.2001.1017446","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1017446","url":null,"abstract":"To avoid using sensors with low biocompatibility and low durability in implantable TAH systems, the authors previously proposed a new method for estimating instantaneous values of flow rate and pressure head on the basis of voltage, current and rotational speed in a motor driven centrifugal pump. The previous in vitro experiments showed that the proposed estimator could automatically compensate for the effect of the change in blood viscosity on the estimation accuracy by employing two kinds of auto-regressive exogenous model. In this study, validity and reliability of this estimation method were ascertained in an acute animal experiment. In the experiment, two centrifugal blood pumps were implanted into an adult goat as a total artificial heart. Results of estimation were compared with true values when blood viscosity was changed by injecting physiological saline. The results indicated that the system could successfully estimate pressure head by compensating the change of viscosity although the estimation accuracy of the in vivo estimation was not so high as that of the previous in vitro tests.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"120 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128082035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}