{"title":"Statistical case study of extracorporeal shock wave lithotripsy","authors":"H. Amasha, B. Al-Eideh","doi":"10.1109/IEMBS.2001.1019703","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1019703","url":null,"abstract":"Extracorporeal shock wave lithotripsy (ESWL) is one of the recent, most common ways of treating patients with urinary (renal and ureteric) stones through non-invasive destruction of stones. Many reports and studies have shown its safety and success. It offers the patient less pain, much less discomfort and less severe complications usually associated with open surgery procedures. This study does not aim to only establish a few facts about this method or treatment; it, also, strives to suggest a statistical model of predicting and planning treatment, which, in turn, saves a great deal of staff's and patient's time. A whole list of factors was studied against each other, and distributions of these factors were deducted. Especially, we have studied the relationships between patient age and number of sessions through the knowledge of the stone size and number of stones.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117055314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Rijkhoff, G. Kurstjens, J. Vidal, A. Rodríguez, A. Borau, T. Sinkjær
{"title":"Intraoperative recording of ENG from human sacral nerve roots","authors":"N. Rijkhoff, G. Kurstjens, J. Vidal, A. Rodríguez, A. Borau, T. Sinkjær","doi":"10.1109/IEMBS.2001.1019040","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1019040","url":null,"abstract":"Intraoperative recoding of electroneurograms (ENG) from the S3 extradural sacral nerve roots was performed in 2 SCI patients. The goal of this work was to study the relation between mechanical stimulation of the urinary bladder, rectum and skin and the resulting ENC-signals. These signals could be used to detect the onset of a bladder contraction. This concept could be used in an implantable neuroprostheses to treat detrusor hyperreflexia. The recorded human signals are consistent with data from animal studies. However, more human studies are needed.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117164141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Properties of auditory temporal integration revealed by mismatch negativity","authors":"S. Kanoh, T. Arai, R. Futami, N. Hoshimiya","doi":"10.1109/IEMBS.2001.1019123","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1019123","url":null,"abstract":"The mismatch negativity (MMN), a component of event-related potentials (ERP), was recorded to investigate the properties of the storage of auditory temporal sequences in the sensory memory. First, the MMN elicited by the infrequent change in a pair of closely spaced tones was evaluated. In ignored condition, it was shown that the MMN was elicited only when the total duration of the tone pair was less than 400 ms. However in attended condition, MMN was also elicited when the duration was 500 ms. This result showed that the function of \"temporal integration\", which integrated the short time history by using a time window, existed in sensory memory, and its maximum period was between 300 ms-400 ms, but this period could be prolonged by the attention process. Second, the relationship between temporal configuration of tone sequence and elicited MMN was evaluated. Temporal configuration was changed by inserting additional tones between the two tones in the tone pair. From this experiment, it was suggested that the performance of auditory sensory memory was influenced by the temporal configuration of the tone sequence to be stored, as well as its total duration. These results may help to approach the neuronal mechanism of auditory scene analysis.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117182498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of Gaussian radial basis function network on protein secondary structures","authors":"T. Ibrikci, M. Guler, M. Açıkkar","doi":"10.1109/IEMBS.2001.1019680","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1019680","url":null,"abstract":"Studies of the radial basis function (RBF) network on protein secondary structures are presented. Secondary structure prediction is a useful first step in understanding how the amino acid sequence of protein determines the native-state. If the secondary structure is known, it is possible to derive a comparatively small number of tertiary structures using the secondary structural element pack. A study of the Gaussian-RBF with different window sizes on the dataset developed by Qian-Sejnowski, and also a dissimilar dataset by Chandonia is given. The RBF network predicts each position in turn-based on a local window of residues, by sliding this window along the length of the sequence. It is shown that the Gaussian RBF network is not an appropriate technique to be used in the prediction of secondary structure for sequence structural state.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"188 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121072322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Parameters and filters for low bit rate wavelet packet compression of magnetic resonance images","authors":"J. Azpiroz-Leehan, J. Lerallut","doi":"10.1109/IEMBS.2001.1017275","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1017275","url":null,"abstract":"We present an analysis of the characteristics of different filters for the compression of magnetic resonance images. Compression rates were 33:1 and 50:1. We compare the performance among different types of wavelets presented in the literature and provide quantitative (percentage of energy retained, peak signal to noise ratio) and qualitative (analysis by a group of seven experts) data to support our conclusions. Different types of coiflets, symlets and biorthogonal wavelets are analyzed, and we conclude that for the images under study (T1 weighed images in three planes), the best results are provided by the biorthogonal spline (Daubechies) wavelet 2,6. Several explanations for these results are mentioned.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127107657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Run-to-run control strategy for diabetes management","authors":"F. Doyle, B. Srinivasan, D. Bonvin","doi":"10.1109/IEMBS.2001.1019492","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1019492","url":null,"abstract":"An approach to insulin injection therapy is introduced that draws from recent ideas in run-to-run control of batch chemical reactors. The method relies on measurements of blood glucose and does not require a mathematical model. Results are shown for simulation case studies involving a detailed pharmacokinetic model.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127197655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The tissue transglutaminase activity does not strengthen cell adhesion during mechanical stretch","authors":"M. Karamanoglu","doi":"10.1109/IEMBS.2001.1017413","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1017413","url":null,"abstract":"Tissue transglutaminase activity (tTGA) has been shown to be important in cell adhesion to an extracellular matrix (EM). However, it is not well know if tTGA improves cell adhesion during mechanical strains imposed on the EM. We have compared the adherence properties of NIH 3T3-fibroblast cell line on fibronectin (FN) and on an EM that lacks the 42KD tTG-binding site. The cells were plated on silicone membranes and were stretched 10% also. Results indicate cell loose their morphology in the absence of tTG binding site and mechanical stretch exacerbates this poor response. The presence of tTGA is important in initial cell adhesion but does not strengthen the cell adhesion to EM.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124830749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hemodynamic aspects of the Berlin ventricle assist device","authors":"I. Avrahami, S. Einav, M. Rosenfeld, K. Affeld","doi":"10.1109/IEMBS.2001.1018968","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1018968","url":null,"abstract":"A new ventricle assist device (VAD), with an improved energy converter unit, was investigated both numerically and experimentally. An experimental continuous digital particle imaging velocimetry (CDPIV) was combined with a computational fluid dynamics (CFD) analysis. These tools complement each other to result in a comprehensive description of the complex 3D, viscous and time-dependent flow field inside the artificial heart ventricle. A 3D numerical model was constructed to simulate the VAD pump and a time-dependent CFD analysis with moving walls was performed to predict the flow field inside the VAD during the cardiac cycle. A commercial finite element package (FIDAP, Fluent Inc., Evanston) was used to solve the Navier-Stokes equations. In the experimental analysis, an optically clear elastic model of the VAD was placed inside a 2D CDPIV system. Continuous flow visualization and CDPIV calculations of the flow were used for validating the CFD simulations. Once validated, the CFD results provide a detailed 3D and time dependent description of the flow field, allowing the identification of stagnation or high shear stress regions.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125023173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Rizzo, G. Cattaneo, I. Castiglioni, M. Reni, D. Vanni, C. Pasquali, C. Landoni, M. Gilardi, S. Cerutti, F. Fazio
{"title":"Integration of CT/PET images for the optimization of radiotherapy planning","authors":"G. Rizzo, G. Cattaneo, I. Castiglioni, M. Reni, D. Vanni, C. Pasquali, C. Landoni, M. Gilardi, S. Cerutti, F. Fazio","doi":"10.1109/IEMBS.2001.1017355","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1017355","url":null,"abstract":"A procedure is presented, based on the combined use of two different tomographic imaging modalities (PET and CT), aimed at the optimization of radiotherapy planning. The combined use of functional PET and anatomical CT studies allows a better definition of the tumour mass with respect to the conventional CT based approach. The proposed procedure consists in: a) spatial registration of CT and PET studies; b) contour drawing based on the combined observation of PET and CT. The set of contours thus obtained, defining optimized volumes of interest for radiotherapy, can be exported to the treatment planning system for designing the radiation beam geometry. The accuracy of the image registration was evaluated by phantom studies and found to be less than 2 pixels in plane and less than slice thickness axially, with respect to CT. The application of the procedure to the case of a patient affected by pancreatic tumour is presented, showing how the treatment planning can be improved by multimodal CT/PET information.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125139037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Soderqvist, C. Carlsson, L. Brodin, H. Elmqvist, H. Kronander, A. Ericsson
{"title":"Design of a single segment conductance catheter for measurement of left ventricular volume","authors":"E. Soderqvist, C. Carlsson, L. Brodin, H. Elmqvist, H. Kronander, A. Ericsson","doi":"10.1109/IEMBS.2001.1018873","DOIUrl":"https://doi.org/10.1109/IEMBS.2001.1018873","url":null,"abstract":"The objective of this paper is to investigate how to best position the sensing electrodes on a single segment conductance catheter, and to calculate the expected performance. Using electrode potential data, obtained with the present five segment conductance catheter in pig experiments, we have interpolated the electrical field at any given point of time, and calculated what volume curve to expect with only two sensing electrodes. Comparison shows that the deviation between our calculated method and the present one is stable and small. Mean deviation with optimized electrode positions was 0.05% per sample, and the maximum deviation found for a single time sample was 2.57%. This indicates that it is possible to build a thin single segment catheter with as good performance as for the present five segment conductance catheter.","PeriodicalId":386546,"journal":{"name":"2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126116889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}