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Japanese Journal of Head and Neck Cancer最新文献

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In Their Words 用他们的话来说
Japanese Journal of Head and Neck Cancer Pub Date : 2020-01-01 DOI: 10.1007/978-3-030-27881-6_14
C. Fundakowski
{"title":"In Their Words","authors":"C. Fundakowski","doi":"10.1007/978-3-030-27881-6_14","DOIUrl":"https://doi.org/10.1007/978-3-030-27881-6_14","url":null,"abstract":"","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86369610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical features of death cases in human papillomavirus related oropharyngeal carcinoma 人乳头瘤病毒相关口咽癌死亡病例的临床特征
Japanese Journal of Head and Neck Cancer Pub Date : 2019-01-01 DOI: 10.5981/jjhnc.45.397
H. Kinjo, Y. Yamashita, T. Ikegami, Yuki Kayo, J. Uezato, S. Agena, Takayuki Uehara, H. Hirakawa, H. Maeda, Mikio Suzuki
{"title":"Clinical features of death cases in human papillomavirus related oropharyngeal carcinoma","authors":"H. Kinjo, Y. Yamashita, T. Ikegami, Yuki Kayo, J. Uezato, S. Agena, Takayuki Uehara, H. Hirakawa, H. Maeda, Mikio Suzuki","doi":"10.5981/jjhnc.45.397","DOIUrl":"https://doi.org/10.5981/jjhnc.45.397","url":null,"abstract":"","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71242904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical analysis for head and neck cancer cases treated with nivolumab in Osaka International Cancer Institute 大阪国际癌症研究所纳武单抗治疗头颈癌的临床分析
Japanese Journal of Head and Neck Cancer Pub Date : 2019-01-01 DOI: 10.5981/JJHNC.45.46
Tomoyuki Otsuka, Takayuki Kimura, R. Koike, Hironori Cho, S. Otozai, T. Yoshii, T. Yagi, T. Fujii
{"title":"Clinical analysis for head and neck cancer cases treated with nivolumab in Osaka International Cancer Institute","authors":"Tomoyuki Otsuka, Takayuki Kimura, R. Koike, Hironori Cho, S. Otozai, T. Yoshii, T. Yagi, T. Fujii","doi":"10.5981/JJHNC.45.46","DOIUrl":"https://doi.org/10.5981/JJHNC.45.46","url":null,"abstract":"要 旨 CheckMate 141 試験において,再発・転移性頭頸部扁平上皮癌に対してニボルマブは医師選択治療と比較して 全生存期間(OS)を有意に延長することが示された。しかし,同試験には扁平上皮癌以外の組織型および上咽頭 癌は含まれていない。今回我々は,当院でニボルマブを投与した頭頸部癌 28 例について後方視的に検討した。本 検討では,非扁平上皮癌が 2 例,上咽頭癌が 9 例含まれていた。全症例の無増悪生存期間(PFS)中央値 4.3 ヶ 月,OS 中央値は未到達であった。測定可能病変を有する 24 例の検討で,奏効率は 16.7%,病勢コントロール率は 54.2%であった。免疫関連有害事象(irAE)は 46.4%で発症し,Grade 3 の irAE は 7.1%で発症した。irAE 発症 群は未発症群と比較して有意な PFS の延長が示された。本検討では非扁平上皮癌や上咽頭癌の症例が含まれてい たが,ニボルマブの有効性が示されていた。","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71242975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Update on paraganglioma and pheochromocytoma based on WHO tumour classification 2017 基于2017年WHO肿瘤分类的副神经节瘤和嗜铬细胞瘤的最新进展
Japanese Journal of Head and Neck Cancer Pub Date : 2019-01-01 DOI: 10.5981/jjhnc.45.350
N. Kimura, K. Shiga, K. Kaneko, K. Takekoshi
{"title":"Update on paraganglioma and pheochromocytoma based on WHO tumour classification 2017","authors":"N. Kimura, K. Shiga, K. Kaneko, K. Takekoshi","doi":"10.5981/jjhnc.45.350","DOIUrl":"https://doi.org/10.5981/jjhnc.45.350","url":null,"abstract":"要 旨 褐色細胞腫(PCC)・パラガングリオーマ(PGL)はいずれも神経堤由来の腫瘍で,PCC は副腎髄質に,PGL は副 腎外に生ずるものを呼ぶ。さらに,PGL は頭頸部に生ずる副交感神経性 PGL(Head & Neck PGL:HNPGL)と,胸 腹部・骨盤内に生ずる交感神経性 PGL に分けられる。HNPGL は頸動脈小体腫瘍(CBT)60%,中耳 PGL 30%,迷 走神経 PGL 10%である。また,家族性 30%,両側性 10–25%,多発 17–37%,転移 4–8%である。PCC/PGL はいず れも転移する腫瘍であることから,WHO 第 4 版ではすべての PCC/PGL を悪性腫瘍と定義づけ,ICD-O3(コード) を付与した。PCC/PGL では現在 20 個ほどの腫瘍感受性遺伝子が判明しており,約 40%は胚細胞変異に伴う腫瘍で, 遺伝子と形質発現の関係が明らかになっている。特に SDHx 変異例では両側性・多発性・家族発生が高頻度である。","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of Vandetanib for unresectable medullary thyroid cancer 万德替尼治疗不可切除甲状腺髓样癌的疗效
Japanese Journal of Head and Neck Cancer Pub Date : 2019-01-01 DOI: 10.5981/jjhnc.45.71
Hiroyuki Yamada, Tomohito Fuke, Kohei Fukukita, Mamika Kaneko, Masahiro Sawa, K. Ueda, D. Kobayashi
{"title":"Effectiveness of Vandetanib for unresectable medullary thyroid cancer","authors":"Hiroyuki Yamada, Tomohito Fuke, Kohei Fukukita, Mamika Kaneko, Masahiro Sawa, K. Ueda, D. Kobayashi","doi":"10.5981/jjhnc.45.71","DOIUrl":"https://doi.org/10.5981/jjhnc.45.71","url":null,"abstract":"Surgical therapy is the main strategy for medullary thyroid cancer, but there is no effective therapy for resectable advanced cases. Vandetanib is a once-daily oral inhibitor of RET kinase, vascular endothelial growth factor receptor, and epidermal growth factor receptor signaling. We experienced a case medicated by Vandetanib for medullary thyroid cancer. A 55-year-old female was diagnosed with medullary thyroid cancer by aspiration cytology of a thyroid tumor and needle biopsy histology. Since FDG-PET showed multiple bone metastases, she was treated with Vandetanib. Serum calcitonin and carcinoembryonic antigen decreased after withdrawal of the medication, and US showed decreased size of the thyroid tumor and cervical lymph nodes similarly. Since PET-CT showed decreased accumulation into these nodules, she was judged to have responded to the treatment. Though Vandetanib is a first-line TKI for unresectable medullary thyroid cancer, the purpose of this therapy is to control progression of the cancer.","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3 Carcinoma of the Buccal Mucosa 3口腔粘膜癌
Japanese Journal of Head and Neck Cancer Pub Date : 2019-01-01 DOI: 10.1055/b-0039-171241
{"title":"3 Carcinoma of the Buccal Mucosa","authors":"","doi":"10.1055/b-0039-171241","DOIUrl":"https://doi.org/10.1055/b-0039-171241","url":null,"abstract":"","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74761915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
27 Surveillance of the Patient 27病人的监护
Japanese Journal of Head and Neck Cancer Pub Date : 2019-01-01 DOI: 10.1055/b-0039-171265
{"title":"27 Surveillance of the Patient","authors":"","doi":"10.1055/b-0039-171265","DOIUrl":"https://doi.org/10.1055/b-0039-171265","url":null,"abstract":"","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"76 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83830502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of double cancer performing total laryngectomy and transhiatal esophagectomy preserving hypopharyngeal mucosa 双癌行全喉切除及经食道切除，保留下咽黏膜1例
Japanese Journal of Head and Neck Cancer Pub Date : 2019-01-01 DOI: 10.5981/jjhnc.45.61
Tomohito Fuke, Hiroyuki Yamada, Kohei Fukukita, Mamika Kaneko, Masahiro Sawa, K. Ueda, D. Kobayashi
{"title":"A case of double cancer performing total laryngectomy and transhiatal esophagectomy preserving hypopharyngeal mucosa","authors":"Tomohito Fuke, Hiroyuki Yamada, Kohei Fukukita, Mamika Kaneko, Masahiro Sawa, K. Ueda, D. Kobayashi","doi":"10.5981/jjhnc.45.61","DOIUrl":"https://doi.org/10.5981/jjhnc.45.61","url":null,"abstract":"要 旨 頭頸部癌治療では重複癌の検索は必須であり,同時重複癌が判明した場合には原発巣や転移部のみならず,患 者の社会的背景や全身状態も考慮した上で治療方針を決定する必要がある。今回,食道癌を合併した喉頭癌症例 に対して同時手術を行った症例を提示する。症例は 72 歳男性で,既往歴として脊髄小脳変性症があった。左声門 T3N2bM0 の精査中に,食道表在癌(Mt,Pw,0-IIc,T1b-SM)が判明した。咽喉頭摘出および食道抜去,挙上胃 管による咽頭食道再建も考慮したが,リスク因子(脊髄小脳変性症の基礎疾患,高度喫煙による閉塞障害)を考慮 して,喉頭摘出・非開胸食道抜去術を行った。喉頭摘出時に可能な限り下咽頭粘膜を温存し,残存する咽頭食道粘 膜の血流障害がないことを確認し,咽頭縫合して縫合不全の軽減目的に甲状腺で被覆し,その尾側で挙上胃管と吻 合した。手術 13 日後より経口摂取を開始したが縫合不全はなく,再発転移はみられていない。","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71243024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
14 Carcinoma of the Hypopharynx 14下咽癌
Japanese Journal of Head and Neck Cancer Pub Date : 2019-01-01 DOI: 10.1055/b-0039-171252
{"title":"14 Carcinoma of the Hypopharynx","authors":"","doi":"10.1055/b-0039-171252","DOIUrl":"https://doi.org/10.1055/b-0039-171252","url":null,"abstract":"","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81782882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
29 The Vessel-Depleted Neck: Microvascular Reconstruction 血管衰竭的颈部:微血管重建
Japanese Journal of Head and Neck Cancer Pub Date : 2019-01-01 DOI: 10.1055/b-0039-171267
{"title":"29 The Vessel-Depleted Neck: Microvascular Reconstruction","authors":"","doi":"10.1055/b-0039-171267","DOIUrl":"https://doi.org/10.1055/b-0039-171267","url":null,"abstract":"","PeriodicalId":38497,"journal":{"name":"Japanese Journal of Head and Neck Cancer","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83454061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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