{"title":"Atrial fibrillation and myocardial infarction: a bidirectional relationship with more questions than answers","authors":"Alfredo Bardají, Gabriel Martín, Sandra Cabrera","doi":"10.1016/j.rec.2025.02.022","DOIUrl":"10.1016/j.rec.2025.02.022","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 9","pages":"Pages 765-767"},"PeriodicalIF":4.9,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Epicardial atrial flutter bridge. Not too deep to go.","authors":"Alejandro Carta-Bergaz, Ángel Arenal-Maíz","doi":"10.1016/j.rec.2025.04.003","DOIUrl":"10.1016/j.rec.2025.04.003","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144033029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roberto Barriales-Villa, Luis Escobar-López, David Vilanova Larena, Joel Salazar-Mendiguchía, Ainara Echeto, Ignacio Hernández, Elena Rebollo-Gómez, Juan Ramón Gimeno
{"title":"Clinical management and healthcare resource utilization among patients with obstructive hypertrophic cardiomyopathy in Spain: a real-world study.","authors":"Roberto Barriales-Villa, Luis Escobar-López, David Vilanova Larena, Joel Salazar-Mendiguchía, Ainara Echeto, Ignacio Hernández, Elena Rebollo-Gómez, Juan Ramón Gimeno","doi":"10.1016/j.rec.2025.04.004","DOIUrl":"10.1016/j.rec.2025.04.004","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Obstructive hypertrophic cardiomyopathy (oHCM), whose symptoms range from dyspnea to heart failure or sudden cardiac death, accounts for approximately 70% of all hypertrophic cardiomyopathy cases. This study aimed to analyze the lack of comprehensive data on oHCM management and determine its clinical and economic burden in Spain.</p><p><strong>Methods: </strong>This retrospective observational study, based on electronic medical records (BIG-PAC), enrolled adults from 1 January 2014, to 31 October 2022, from the time of HCM diagnosis. The analysis focused on epidemiology, patient characteristics and management, transitions between New York Heart Association (NYHA) functional classes, healthcare resource utilization (HCRU), and associated costs.</p><p><strong>Results: </strong>A total of 752 oHCM patients were included (mean age: 63 years; male: 57.6%). NYHA functional classification at diagnosis was as follows: 12% NYHA-I, 47.9% NYHA-II, 31.5% NYHA-III, and 8.6% NYHA-IV. The prevalence of HCM and oHCM was 28 and 7 per 10 000 individuals, respectively. Patients received a mean of 2.4 (SD 1.5) treatments, mainly beta-blockers. Only patients in NYHA classes III and IV underwent septal reduction therapies (SRT) (13.1% and 47.7%, respectively); 38.7% and 35.5% of NYHA-III and -IV patients who received SRT, respectively, improved to a lower NYHA class. Symptom severity, as measured by NYHA class, was associated with increased rates of hospitalization, cardiovascular events, mortality, and higher HCRU and costs. Mean annualized, direct, adjusted health care costs ranged from €4142 (95%CI: €3110-€5175) in NYHA-I to €16 677 (95%CI: €15 482-€17 872) in NYHA-IV.</p><p><strong>Conclusions: </strong>This is the first Spanish study to evaluate oHCM patient management and to demonstrate its impact in terms of increased hospitalizations, mortality, HCRU, and healthcare costs, trends that parallel the progression of symptoms by NYHA functional class. Patients who underwent SRT showed partial symptom improvement.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Òscar Miró , Olivier Peyrony , Joan Carles Trullàs , Aitor Alquézar-Arbé , Julio Núñez , Pedro López-Ayala , Javier Jacob , Héctor Bueno , Manuel Montero-Pérez-Barquero , José Carlos Arévalo-Lorido , Rafael de la Espriella , Gema Miñana , Juan Sanchis , Pere Llorens
{"title":"Identification of phenotypes in heart failure with preserved ejection fraction among 8161 patients from 3 Spanish cohorts","authors":"Òscar Miró , Olivier Peyrony , Joan Carles Trullàs , Aitor Alquézar-Arbé , Julio Núñez , Pedro López-Ayala , Javier Jacob , Héctor Bueno , Manuel Montero-Pérez-Barquero , José Carlos Arévalo-Lorido , Rafael de la Espriella , Gema Miñana , Juan Sanchis , Pere Llorens","doi":"10.1016/j.rec.2025.02.021","DOIUrl":"10.1016/j.rec.2025.02.021","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>To identify phenotypes in heart failure with preserved ejection fraction (HFpEF), compare mortality, and investigate whether treatments have different effects according to phenotype.</div></div><div><h3>Methods</h3><div>We performed a secondary analysis of 8161 patients with HFpEF included in Spanish cardiology (INCLIVA), internal medicine (RICA), and emergency (EAHFE) registries. Phenotypic clusters based on 16 baseline characteristics were identified using latent class analysis. We analyzed crude and treatment-adjusted 1-year survival, the associations between each treatment and mortality, and their interactions with phenotype.</div></div><div><h3>Results</h3><div>We identified 4 distinct clusters. One-year mortality was 18.7%. Cluster 4 (younger women with a valvular heart disease phenotype) had the lowest mortality (13.7%; reference category), which increased progressively in cluster 2 (cardiometabolic phenotype; mortality: 15.7%; adjusted HR, 1.28; 95%<span>C</span>I, 1.06-1.54), cluster 3 (very elderly female phenotype; mortality: 20.4%; adjusted HR, 1.63; 95%CI, 1.40-1.90), and cluster 1 (male phenotype with cardiomyopathy; mortality: 24.0%; adjusted HR, 1.81; 95%CI, 1.53-2.13). The results were very similar when each registry was analyzed individually. Treatment with renin-angiotensin system inhibitors was associated with better survival in all clusters, beta-blockers were beneficial in cluster 1, and anticoagulants in cluster 4. However, none of the treatments show</div><div>ed a differential association with prognosis according to phenotype.</div></div><div><h3>Conclusions</h3><div>This study defines 4 HFpEF phenotypes with significantly different prognoses. Among the treatments analyzed, only renin-angiotensin system inhibitors seemed to have a generalized survival benefit, and none demonstrated a differential effect based on phenotype.</div></div>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 10","pages":"Pages 896-905"},"PeriodicalIF":4.9,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prognostic benefit of percutaneous revascularization for chronic total coronary occlusions. Paradoxes and contradictions in an endless debate","authors":"Alfonso Jurado-Román , José M. Montero-Cabezas","doi":"10.1016/j.rec.2025.03.009","DOIUrl":"10.1016/j.rec.2025.03.009","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 10","pages":"Pages 860-862"},"PeriodicalIF":4.9,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Enrique Pérez-de la Sota, Andrea Eixerés-Esteve, Jorge Enrique Centeno-Rodríguez, María Jesús López-Gude, Christian Muñoz-Guijosa
{"title":"Impella implantation through the brachiocephalic artery: an alternative for left support in patients with small axillary access.","authors":"Enrique Pérez-de la Sota, Andrea Eixerés-Esteve, Jorge Enrique Centeno-Rodríguez, María Jesús López-Gude, Christian Muñoz-Guijosa","doi":"10.1016/j.rec.2025.02.020","DOIUrl":"https://doi.org/10.1016/j.rec.2025.02.020","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ilaria Dentamaro, Andrea Igoren Guaricci, Yassin Belahnech, Paolo Basile, Gianluca Pontone, José Fernando Rodríguez Palomares
{"title":"Feature tracking cardiovascular magnetic resonance to predict major adverse cardiovascular events in patients with cardiac amyloidosis.","authors":"Ilaria Dentamaro, Andrea Igoren Guaricci, Yassin Belahnech, Paolo Basile, Gianluca Pontone, José Fernando Rodríguez Palomares","doi":"10.1016/j.rec.2025.04.002","DOIUrl":"https://doi.org/10.1016/j.rec.2025.04.002","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roberto Pastor-Barriuso, Alicia Padrón-Monedero, Fernando J García López, Javier Almazán-Isla, Jesús de Pedro-Cuesta, Javier Damián
{"title":"Association of disability with cardiovascular mortality in the community-dwelling Spanish adult population.","authors":"Roberto Pastor-Barriuso, Alicia Padrón-Monedero, Fernando J García López, Javier Almazán-Isla, Jesús de Pedro-Cuesta, Javier Damián","doi":"10.1016/j.rec.2025.03.008","DOIUrl":"10.1016/j.rec.2025.03.008","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Adults with disability have higher risk of all-cause mortality, but evidence on their risk of cardiovascular mortality is scarce. This study aimed to evaluate the association between disability severity and mortality from cardiovascular causes among community-dwelling adults.</p><p><strong>Methods: </strong>A representative cohort of 105 743 community-dwelling Spanish adults aged 40 years or older was screened for disability severity within the framework of the international classification of functioning, disability, and health from 2007 to 2008 and was followed up for cardiovascular mortality until 2017. Five- and 10-year cardiovascular mortality risks in each disability category were standardized by sociodemographic characteristics using inverse probability weighting and corrected for competing causes of death. Bias analyses were performed to quantify residual confounding by unmeasured baseline cardiovascular conditions.</p><p><strong>Results: </strong>The baseline prevalence of disability was 16.2% (95%CI, 15.9-16.4), including 11.5% with mild, 3.5% with moderate, and 1.1% with severe/complete disability. Compared with no disability, the standardized 5-year risk ratios for cardiovascular mortality (95%CI) were 1.70 (1.49-1.93), 3.92 (3.23-4.76), and 4.77 (3.42-6.66) for mild, moderate, and severe/complete disability, respectively, corresponding to 11.7 (8.4-15.0), 49.0 (37.0-60.9), and 63.1 (37.0-89.3) excess cardiovascular deaths per 1000 persons. The positive confounding in these risk ratios by unmeasured prevalent cardiovascular conditions was 5.9%. Results were similar for ischemic heart disease and cerebrovascular mortality and were sustained after 10 years of follow-up.</p><p><strong>Conclusions: </strong>Adults with disability have higher mortality from cardiovascular causes. Conditions that increase cardiovascular risk in people with disability should be investigated. Preventive measures and health promotion initiatives are needed to reduce the risk of cardiovascular mortality in this population.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}