{"title":"Risk of severe cardiovascular events following COPD exacerbations: results from the EXACOS-CV study in Spain","authors":"Salud Santos , Nicolás Manito , Joaquín Sánchez-Covisa , Ignacio Hernández , Carmen Corregidor , Luciano Escudero , Kirsty Rhodes , Clementine Nordon","doi":"10.1016/j.rec.2024.06.003","DOIUrl":"10.1016/j.rec.2024.06.003","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>This real-world study—the first of its kind in a Spanish population—aimed to explore severe risk for cardiovascular events and all-cause death following exacerbations in a large cohort of patients with chronic obstructive pulmonary disease (COPD).</div></div><div><h3>Methods</h3><div>We included individuals with a COPD diagnosis code between 2014 and 2018 from the BIG-PAC health care claims database. The primary outcome was a composite of a first severe cardiovascular event (acute coronary syndrome, heart failure decompensation, cerebral ischemia, arrhythmia) or all-cause death following inclusion in the cohort. Time-dependent Cox proportional hazards models estimated HRs for associations between exposed time periods (1-7, 8-14, 15-30, 31-180, 181-365, and ><!--> <!-->365 days) following an exacerbation of any severity, and following moderate or severe exacerbations separately (vs unexposed time before a first exacerbation following cohort inclusion).</div></div><div><h3>Results</h3><div>During a median follow-up of 3.03 years, 18 901 of 24 393 patients (77.5%) experienced ≥ 1 moderate/severe exacerbation, and 8741 (35.8%) experienced the primary outcome. The risk of a severe cardiovascular event increased following moderate/severe COPD exacerbation onset vs the unexposed period, with rates being most increased during the first 1 to 7 days following exacerbation onset (HR, 10.10; 95%CI, 9.29-10.97) and remaining increased ><!--> <!-->365 days after exacerbation onset (HR, 1.65; 95%CI, 1.49-1.82).</div></div><div><h3>Conclusions</h3><div>The risk of severe cardiovascular events or death increased following moderate/severe exacerbation onset, illustrating the need for proactive multidisciplinary care of patients with COPD to prevent exacerbations and address other cardiovascular risk factors.</div></div>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 2","pages":"Pages 138-150"},"PeriodicalIF":7.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernando Alfonso , Jorge Salamanca , Iván Núñez-Gil , Náyade Del Prado , Nicolás Rosillo , Javier Elola
{"title":"Trends in hospital admissions and mortality for tako-tsubo syndrome in Spain","authors":"Fernando Alfonso , Jorge Salamanca , Iván Núñez-Gil , Náyade Del Prado , Nicolás Rosillo , Javier Elola","doi":"10.1016/j.rec.2024.08.013","DOIUrl":"10.1016/j.rec.2024.08.013","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 2","pages":"Pages 158-160"},"PeriodicalIF":7.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Revascularization in ischemic cardiomyopathy. Is viability testing still viable?","authors":"James F. Howick V , Bernard J. Gersh","doi":"10.1016/j.rec.2024.10.004","DOIUrl":"10.1016/j.rec.2024.10.004","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 2","pages":"Pages 78-81"},"PeriodicalIF":7.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142509854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ki Hong Choi , Sang Yoon Lee , Taek Kyu Park , Joo Myung Lee , Young Bin Song , Joo-Yong Hahn , Seung-Hyuk Choi , Chul-Min Ahn , Cheol Woong Yu , Ik Hyun Park , Woo Jin Jang , Hyun-Joong Kim , Jang-Whan Bae , Sung Uk Kwon , Hyun-Jong Lee , Wang Soo Lee , Jin-Ok Jeong , Sang-Don Park , Tae-Soo Kang , Hyeon-Cheol Gwon , Jeong Hoon Yang
{"title":"Cardiogenic shock complicating acute myocardial infarction and multivessel disease: revascularization strategy according to ischemic territory","authors":"Ki Hong Choi , Sang Yoon Lee , Taek Kyu Park , Joo Myung Lee , Young Bin Song , Joo-Yong Hahn , Seung-Hyuk Choi , Chul-Min Ahn , Cheol Woong Yu , Ik Hyun Park , Woo Jin Jang , Hyun-Joong Kim , Jang-Whan Bae , Sung Uk Kwon , Hyun-Jong Lee , Wang Soo Lee , Jin-Ok Jeong , Sang-Don Park , Tae-Soo Kang , Hyeon-Cheol Gwon , Jeong Hoon Yang","doi":"10.1016/j.rec.2024.05.005","DOIUrl":"10.1016/j.rec.2024.05.005","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>The association of revascularization strategy with clinical outcomes according to the ischemic territory of nonculprit lesion has not been documented in patients with acute myocardial infarction complicated by cardiogenic shock (AMI-CS). This study aimed to compare outcomes between culprit-only and immediate multivessel percutaneous coronary intervention (PCI) according to ischemic territory in patients with AMI-CS.</div></div><div><h3>Methods</h3><div>A total of 536 patients with AMI-CS and multivessel disease from the SMART-RESCUE registry were categorized according to ischemic territory (nonculprit left main/proximal left anterior descending artery [LM/pLAD] vs culprit LM/pLAD vs no LM/pLAD). The primary outcome was a patient-oriented composite endpoint (POCE) consisting of all-cause death, myocardial infarction, rehospitalization due to heart failure, or repeat revascularization at 1 year.</div></div><div><h3>Results</h3><div>Among the total population, 108 patients had nonculprit LM/pLAD, 228 patients had culprit LM/pLAD, and 200 patients had no LM/pLAD, with the risk of POCE being higher in patients with large ischemic territory lesions (53.6% vs 53.4% vs 39.6%; <em>P</em> = .02). Multivessel PCI was associated with a significantly lower risk of POCE compared with culprit-only PCI in patients with nonculprit LM/pLAD (40.7% vs 66.9%; HR, 0.52; 95%CI, 0.29-0.91; <em>P<!--> </em>=<!--> <!-->.02), but not in those with culprit LM/pLAD (<em>P<!--> </em>=<!--> <!-->.46) or no LM/pLAD (<em>P<!--> </em>=<!--> <!-->.47). A significant interaction existed between revascularization strategy and large nonculprit ischemic territory (<em>P<!--> </em>=<!--> <!-->.03).</div></div><div><h3>Conclusions</h3><div>Large ischemic territory involvement was associated with worse clinical outcomes in patients with AMI-CS and multivessel disease. Immediate multivessel PCI might improve clinical outcomes in patients with a large nonculprit ischemic burden.</div></div>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 2","pages":"Pages 97-106"},"PeriodicalIF":7.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141180661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Ruberti, Pedro Cepas-Guillén, Julio Echarte-Morales, Dabit Arzamendi, Vanessa Moñivas, Fernando Carrasco-Chinchilla, Manuel Pan, Luis Nombela-Franco, Isaac Pascual, Claudio E Guerreiro, Tomás Benito-González, Ruth Pérez, Iván Gómez-Blázquez, Ignacio J Amat-Santos, Eduardo Flores-Umanzor, Ignacio Cruz-González, Ángel Sánchez-Recalde, Ana Belén Cid Álvarez, Manuel Barreiro-Pérez, Laura Sanchis, Chi-Hion Li, Berenice Caneiro-Queija, María Del Trigo, José David Martínez-Carmona, Dolores Mesa, Pilar Jiménez Quevedo, Pablo Avanzas, Rodrigo Estévez-Loureiro, Xavier Freixa
{"title":"Efficacy of transcatheter edge-to-edge repair for cardiac implantable electronic device-associated tricuspid regurgitation: insights from the TRI-SPA registry.","authors":"Andrea Ruberti, Pedro Cepas-Guillén, Julio Echarte-Morales, Dabit Arzamendi, Vanessa Moñivas, Fernando Carrasco-Chinchilla, Manuel Pan, Luis Nombela-Franco, Isaac Pascual, Claudio E Guerreiro, Tomás Benito-González, Ruth Pérez, Iván Gómez-Blázquez, Ignacio J Amat-Santos, Eduardo Flores-Umanzor, Ignacio Cruz-González, Ángel Sánchez-Recalde, Ana Belén Cid Álvarez, Manuel Barreiro-Pérez, Laura Sanchis, Chi-Hion Li, Berenice Caneiro-Queija, María Del Trigo, José David Martínez-Carmona, Dolores Mesa, Pilar Jiménez Quevedo, Pablo Avanzas, Rodrigo Estévez-Loureiro, Xavier Freixa","doi":"10.1016/j.rec.2025.01.010","DOIUrl":"10.1016/j.rec.2025.01.010","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>This study aimed to assess the effectiveness and clinical outcomes of tricuspid transcatheter edge-to-edge repair (T-TEER) in patients with cardiac implantable electronic devices (CIEDs).</p><p><strong>Methods: </strong>This subanalysis of the Transcatheter Tricuspid Valve Repair in Spain (TRI-SPA) registry included patients with at least severe tricuspid regurgitation (TR) who were treated with T-TEER between June 2020 and May 2023 in Spain. Patients with CIEDs and no or mild tricuspid lead-leaflet interaction were compared with those without CIEDs. The primary composite endpoint was all-cause mortality, heart failure-related hospitalization, and tricuspid valve reintervention at 12 months.</p><p><strong>Results: </strong>Among 310 patients (mean age 75.5±9.1 years, 70% female) with significant TR treated with T-TEER, 35 (11%) had CIEDs. Device implantation success was high in both groups (97.1% in the CIED group vs 96.4% in the non-CIED group, P=.81), with a similar rate of ≤2+ residual TR (84.9% in the CIED group vs 91.0% in the non-CIED group, P=.26). Patients with CIEDs experienced comparable rates of the primary composite endpoint to the non-CIED group (23.8% vs 19.1%, respectively, HR, 1.40; 95%CI, 0.60-3.31; P=.44), sustained successful TR reduction (δ 2+ in 55.0% vs 73.8%, P=.07), and functional improvement (NYHA class I/II 81.8% vs 79.9%, P=.79).</p><p><strong>Conclusions: </strong>In a real-world setting, T-TEER seems to be an effective therapeutic option for selected patients with more than moderate TR and CIEDs with no or mild lead-leaflet interaction, offering comparable cardiovascular outcomes and clinical improvement to those without leads. However, the presence of CIEDs may represent an independent risk factor for TR recurrence.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jesús Peteiro, Marina Combarro, Gonzalo Barge-Caballero, Alberto Bouzas-Mosquera, José Larrañaga-Moreira, José M Vázquez-Rodríguez
{"title":"Apical sparing during exercise echocardiography for suspected cardiac amyloidosis.","authors":"Jesús Peteiro, Marina Combarro, Gonzalo Barge-Caballero, Alberto Bouzas-Mosquera, José Larrañaga-Moreira, José M Vázquez-Rodríguez","doi":"10.1016/j.rec.2025.01.009","DOIUrl":"10.1016/j.rec.2025.01.009","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sergio López-Tejero, Pablo Antúnez-Muiños, Miguel Hernández-Hidalgo, Ana Martín-García, Pedro L Sánchez-Fernández, Ignacio Cruz-González
{"title":"Left atrial appendage occlusion in patients with atrial fibrillation and cancer. Short- and mid-term outcomes.","authors":"Sergio López-Tejero, Pablo Antúnez-Muiños, Miguel Hernández-Hidalgo, Ana Martín-García, Pedro L Sánchez-Fernández, Ignacio Cruz-González","doi":"10.1016/j.rec.2024.12.013","DOIUrl":"10.1016/j.rec.2024.12.013","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Boris Kuzmicic Calderón, Bernardita Martínez Galdames, Mario Hassi Thumala, Jorge Van Grieken, Jovan Kuzmicic
{"title":"Clinical association of the SCN5A c.2302A>G variant (p.Ile768Val) with Brugada syndrome.","authors":"Boris Kuzmicic Calderón, Bernardita Martínez Galdames, Mario Hassi Thumala, Jorge Van Grieken, Jovan Kuzmicic","doi":"10.1016/j.rec.2024.12.014","DOIUrl":"10.1016/j.rec.2024.12.014","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk factors for the progression of aortic regurgitation following surgical repair of sinus of Valsalva aneurysms. Analysis of 317 cases.","authors":"Tianyu Chen, Jianzheng Cen, Shusheng Wen, Jimei Chen, Jian Zhuang, Xiaobing Liu","doi":"10.1016/j.rec.2025.01.004","DOIUrl":"10.1016/j.rec.2025.01.004","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}