Revista española de cardiología (English ed.)最新文献

{"title":"Transcatheter closure of multiple coronary artery fistulas: a coronary computed tomography angiography-based anatomic classification","authors":"Peijian Wei ,&nbsp;Yihang Li ,&nbsp;Fengwen Zhang ,&nbsp;Zhongying Xu ,&nbsp;Liang Xu ,&nbsp;Junyi Wan ,&nbsp;Shiguo Li ,&nbsp;Wenbin Ouyang ,&nbsp;Shouzheng Wang ,&nbsp;Gejun Zhang ,&nbsp;Gary Tse ,&nbsp;Jeffrey Shi Kai Chan ,&nbsp;Fang Fang ,&nbsp;Xiangbin Pan","doi":"10.1016/j.rec.2024.06.006","DOIUrl":"10.1016/j.rec.2024.06.006","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>This study aimed to retrospectively analyze the anatomical characteristics and classification of multiple coronary artery fistulas (MCAFs), and to compare the outcomes of transcatheter closure between MCAFs and single fistulas.</div></div><div><h3>Methods</h3><div>All patients who underwent attempts at transcatheter closure of coronary artery fistulas (CAFs) at Fuwai Hospital from 2010 to 2023 were retrospectively reviewed. Patients were categorized into single fistula and MCAFs groups, and anatomical characteristics and transcatheter closure outcomes were compared between the 2 groups.</div></div><div><h3>Results</h3><div>This retrospective study included 146 patients who underwent attempted transcatheter closure of CAFs, with a 14.38% failure rate. Among the 146 patients with CAFs, 32.19% were identified as having MCAFs, with types I, II, and III constituting 40.43%, 42.55%, and 17.02%, respectively. Unlike single fistulas, which predominantly originated from the right coronary artery and terminated in the left ventricle, MCAFs mainly had simultaneous origins from the right coronary artery and left anterior descending artery (29.79%), and predominantly drained into the pulmonary artery (70.21%), with a notable prevalence of plexus-like morphology (38.3% vs 2.02%, <em>P</em> <!-->&lt;<!--> <!-->.001). The success rate of transcatheter closure was significantly lower for multiple fistulas compared with single fistula (64.29% vs 84.34%, <em>P</em> <!-->=<!--> <!-->.011). Multivariate regression analysis indicated that the risk of closure failure for MCAFs was 2.64 times that of single fistulas.</div></div><div><h3>Conclusions</h3><div>MCAFs are common among CAFs and can be classified into 3 types based on the number and location of their origins and terminations. The risk of failure of transcatheter closure is significantly higher in MCAFs than in single fistulas.</div></div>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 3","pages":"Pages 206-217"},"PeriodicalIF":7.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141621150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transapical transcatheter mitral valve replacement for mitral valve disease: an Iberian experience","authors":"Eva Gutiérrez-Ortiz ,&nbsp;Javier Cobiella ,&nbsp;Christian Muñoz-Guijosa ,&nbsp;Rui C. Teles ,&nbsp;Rodrigo Estévez-Loureiro ,&nbsp;Vanessa Moñivas ,&nbsp;Ander Regueiro ,&nbsp;Sara Blasco-Turrión ,&nbsp;Patricia Mahía ,&nbsp;Danela Figuereo Beltre ,&nbsp;Pedro Freitas ,&nbsp;Miguel Piñón ,&nbsp;Ignacio J Amat-Santos ,&nbsp;Ignasi Julià Amill ,&nbsp;Tiago Nolasco ,&nbsp;Daniel Pereda ,&nbsp;Carlos Martín López ,&nbsp;Luis Nombela-Franco","doi":"10.1016/j.rec.2024.07.004","DOIUrl":"10.1016/j.rec.2024.07.004","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Transcatheter mitral valve replacement (TMVR) is an emerging treatment alternative for mitral valve (MV) disease in patients who were ineligible for surgical intervention or edge-to-edge repair. This study aimed to assess the short- and mid-term outcomes of this procedure.</div></div><div><h3>Methods</h3><div>We conducted a prospective registry to include the initial experience with symptomatic, consecutive patients who underwent TMVR using the transapical Tendyne system at 7 centers in the Iberian Peninsula. Baseline clinical and imaging data, periprocedural information, and follow-up assessments were collected at 1 month and 1 year.</div></div><div><h3>Results</h3><div>A total of 40 patients (mean age 78.5 years [76-82], 47,5% males) underwent TMVR. The majority had significant surgical risk, comorbidities, and advanced functional class. All patients had significant mitral regurgitation (MR), except for 2 with severe stenosis. Previous MV intervention and off-label indication for the procedure were present in 4 (10.0%) and 8 (20.0%) patients, respectively. Technical success was recorded in 100%, device success in 95.0%, and procedural success in 85.0% at 30-day. All-cause mortality was 2.5% and 17.5% at the 1-month and 1-year follow-up, respectively. MR reduction (≤ 1) and functional class improvement (NYHA I-II) were observed at 1 year in 93.9% and 87.9% of survivors, respectively.</div></div><div><h3>Conclusions</h3><div>Treatment with TMVR produced enduring resolution of MV disease and notable functional enhancement at 1 year of follow-up. The procedure demonstrated a satisfactory early safety profile, although 1-year mortality remained relatively high in this high-risk population.</div></div>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 3","pages":"Pages 229-238"},"PeriodicalIF":7.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141789352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Black hole-type electronic health records. Enough is enough!","authors":"Héctor Bueno","doi":"10.1016/j.rec.2024.11.013","DOIUrl":"10.1016/j.rec.2024.11.013","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 3","pages":"Pages 286-287"},"PeriodicalIF":7.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142915751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent advances in precision nutrition and cardiometabolic diseases","authors":"Miguel A. Martínez-González ,&nbsp;Francisco J. Planes ,&nbsp;Miguel Ruiz-Canela ,&nbsp;Estefanía Toledo ,&nbsp;Ramón Estruch ,&nbsp;Jordi Salas-Salvadó ,&nbsp;Rafael Valdés-Más ,&nbsp;Pedro Mena ,&nbsp;Olga Castañer ,&nbsp;Montse Fitó ,&nbsp;Clary Clish ,&nbsp;Rikard Landberg ,&nbsp;Clemens Wittenbecher ,&nbsp;Liming Liang ,&nbsp;Marta Guasch-Ferré ,&nbsp;Rosa M. Lamuela-Raventós ,&nbsp;Dong D. Wang ,&nbsp;Nita Forouhi ,&nbsp;Cristina Razquin ,&nbsp;Frank B. Hu","doi":"10.1016/j.rec.2024.09.003","DOIUrl":"10.1016/j.rec.2024.09.003","url":null,"abstract":"<div><div>A growing body of research on nutrition omics has led to recent advances in cardiovascular disease epidemiology and prevention. Within the PREDIMED trial, significant associations between diet-related metabolites and cardiovascular disease were identified, which were subsequently replicated in independent cohorts. Some notable metabolites identified include plasma levels of ceramides, acyl-carnitines, branched-chain amino acids, tryptophan, urea cycle pathways, and the lipidome. These metabolites and their related pathways have been associated with incidence of both cardiovascular disease and type 2 diabetes. Future directions in precision nutrition research include: <em>a)</em> developing more robust multimetabolomic scores to predict long-term risk of cardiovascular disease and mortality; <em>b)</em> incorporating more diverse populations and a broader range of dietary patterns; and <em>c)</em> conducting more translational research to bridge the gap between precision nutrition studies and clinical applications.</div></div>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 3","pages":"Pages 263-271"},"PeriodicalIF":7.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142366826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"David after Ross: a possible option before Bentall?","authors":"César A. Rodríguez Canedo ,&nbsp;Ramón Pérez-Caballero ,&nbsp;Carlos A. Pardo Pardo ,&nbsp;José F. Gutiérrez Díez ,&nbsp;Raquel Prieto-Arevalo ,&nbsp;Juan-Miguel Gil-Jaurena","doi":"10.1016/j.rec.2024.08.010","DOIUrl":"10.1016/j.rec.2024.08.010","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 3","pages":"Pages 277-279"},"PeriodicalIF":7.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142401569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catheter-directed interventions in acute pulmonary embolism. Position statement of SEC-Interventional Cardiology Association/SEC-Ischemic Heart Disease and Acute Cardiovascular Care Association/SEC-Working Group on Pulmonary Hypertension","authors":"Pablo Salinas ,&nbsp;Ana Belén Cid Álvarez ,&nbsp;Pablo Jorge Pérez ,&nbsp;María Eugenia Vázquez-Álvarez ,&nbsp;Alfonso Jurado-Román ,&nbsp;Miriam Juárez ,&nbsp;Miguel Corbí-Pascual ,&nbsp;Maite Velázquez Martín ,&nbsp;Jesús Jiménez-Mazuecos ,&nbsp;Sandra Ofelia Rosillo Rodríguez ,&nbsp;Valeriano Ruiz Quevedo ,&nbsp;María Lázaro ,&nbsp;Ana Viana-Tejedor ,&nbsp;Javier Martín Moreiras ,&nbsp;Roberto Martín-Asenjo","doi":"10.1016/j.rec.2024.09.011","DOIUrl":"10.1016/j.rec.2024.09.011","url":null,"abstract":"<div><div>Pulmonary embolism (PE) is the leading cause of hospital death and the third most frequent cause of cardiovascular mortality. Traditionally, treatment options have included anticoagulation, thrombolysis, or surgery; however, catheter-directed interventions (CDI), including catheter-directed thrombolysis and aspiration thrombectomy, have been developed for patients with intermediate- or high-risk PE. These techniques can rapidly improve right ventricular function, hemodynamic status, and mortality in some patients, although there is a lack of evidence from randomized controlled trials. This document, prepared by the Interventional Cardiology Association, the Association of Ischemic Heart Disease and Acute Cardiovascular Care, and the Working Group on Pulmonary Hypertension of the Spanish Society of Cardiology (SEC), reviews the current recommendations and available evidence on the management of PE. It emphasizes the importance of rapid response teams, risk stratification, and early patient monitoring in identifying candidates for reperfusion. Based on existing clinical evidence on CDI, the document discusses various clinical scenarios and provides guidance on patient selection, particularly in situations of uncertainty due to insufficient evidence. Lastly, it describes periprocedural support, highlighting the necessary multidisciplinary approach to improve outcomes and reduce morbidity and mortality in patients with PE.</div></div>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 3","pages":"Pages 239-251"},"PeriodicalIF":7.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early unloading and clinical outcomes in patients with fulminant myocarditis undergoing VA-ECMO: results of a multicenter retrospective study","authors":"Minjung Bak ,&nbsp;Junho Hyun ,&nbsp;Hyukjin Park ,&nbsp;Hyung Yoon Kim ,&nbsp;Seonhwa Lee ,&nbsp;In-Cheol Kim ,&nbsp;So Ree Kim ,&nbsp;Mi-Na Kim ,&nbsp;Kyung-Hee Kim ,&nbsp;Jeong Hoon Yang","doi":"10.1016/j.rec.2024.06.004","DOIUrl":"10.1016/j.rec.2024.06.004","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Although venoarterial extracorporeal membrane oxygenation (VA-ECMO) provides effective cardiocirculatory support in patients with fulminant myocarditis, the most effective timing of venting is uncertain. We aimed to investigate the benefit of early venting among patients who underwent VA-ECMO for fulminant myocarditis.</div></div><div><h3>Methods</h3><div>Among 841 patients with acute myocarditis from 7 hospitals in the Republic of Korea, 217 patients with fulminant myocarditis who underwent VA-ECMO were included in this analysis. The patients were categorized into 2 groups: an early unloading group that underwent venting within 24<!--> <span>hours of ECMO insertion, and the no or delayed unloading group. The primary outcome was a composite of death, cardiac replacement, or cardiovascular rehospitalization.</span></div></div><div><h3>Results</h3><div>Among 217 patients, 56 underwent early venting, 54 underwent delayed venting, and 107 did not undergo venting. On spline curves in 110 patients who underwent venting, rapid deterioration was observed as the timing of venting was delayed. The incidence of the primary outcome was lower in the early venting group than in the no or delayed unloading group (37.5% vs 58.4%; HR, 0.491; 95%CI, 0.279-0.863; <em>P</em> <!-->=<!--> <!-->.014). Among patients not experiencing the primary outcome within 6 months, clinical outcomes were similar after 6 months (<em>P</em> <!-->=<!--> <!-->.375).</div></div><div><h3>Conclusions</h3><div>Early left heart unloading within 24<!--> <!-->hours of ECMO insertion is associated with a lower risk of a composite of death, cardiac replacement therapy, and cardiovascular rehospitalization in patients with fulminant myocarditis undergoing VA-ECMO. Registered at ClinicalTrials.gov (NCT05933902).</div></div>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 3","pages":"Pages 176-184"},"PeriodicalIF":7.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant intraventricular thrombus with multiple embolisms: anticoagulation or surgery?","authors":"Diana Ladera Santos ,&nbsp;Ignacio Gallo Fernández ,&nbsp;Manuel Anguita Sánchez","doi":"10.1016/j.rec.2024.08.012","DOIUrl":"10.1016/j.rec.2024.08.012","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 3","pages":"Pages 282-283"},"PeriodicalIF":7.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peripheral access ultrafiltration in adults with complex congenital heart disease and refractory congestion","authors":"Borja Guerrero Cervera ,&nbsp;Raquel López-Vilella ,&nbsp;Joaquín Rueda Soriano ,&nbsp;Víctor Donoso Trenado ,&nbsp;Francisco Buendía Fuentes ,&nbsp;Luis Almenar Bonet","doi":"10.1016/j.rec.2024.08.015","DOIUrl":"10.1016/j.rec.2024.08.015","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 3","pages":"Pages 274-277"},"PeriodicalIF":7.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142509848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide 1 receptor agonists and cancer mortality. A real-world registry","authors":"David García-Vega ,&nbsp;Sergio Cinza-Sanjurjo ,&nbsp;Carlos Tilves-Bellas ,&nbsp;Sonia Eiras ,&nbsp;José R. González-Juanatey","doi":"10.1016/j.rec.2024.07.003","DOIUrl":"10.1016/j.rec.2024.07.003","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Sodium-glucose cotransporter 2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP1ra) reduce cardiovascular events through different mechanisms, but their association with cancer remains unclear. The aim of this study was to compare the effect of combined treatment (SGLT2i and GLP1ra) and monotherapy (SGLT2i or GLP1ra) on hospitalization and/or death from cancer in a general population and a subgroup of patients with cardiovascular disease (CVD).</div></div><div><h3>Methods</h3><div>We conducted a nonconcurrent observational prospective study of patients prescribed SGLT2i, GLP1ra, or both. Multinomial propensity scores were performed in the entire population and in a subgroup of patients with CVD. A multivariate Cox regression analysis was used to determine the hazard ratio (HR) for age, sex, risk factors, and treatment for each outcome.</div></div><div><h3>Results</h3><div>We included 14 709 patients (11366 with SGLT2i, 1016 with GLP1ra, and 2327 with both treatments) from treatment initiation. Diabetes was present in 97% of the patients. The subgroup with CVD included 4957 (33.7%) patients. After a median of 33 months of follow-up, the risk of adverse cancer events was similar between patients with and without CVD (3.4% or 3.7%, respectively). The main risk factors for cancer mortality were male sex and age. Combined treatment and its duration reduced the risk of cancer mortality compared with monotherapy with SGLT2i or GLP1ra in the overall population (HR, 0.2216; 95%CI, 0.1106-0.4659; <em>P</em> <!-->&lt;<!--> <!-->.001; and HR, 0.1928; 95%CI, 0.071-0.5219; <em>P</em> <!-->=<!--> <!-->.001, respectively) and in the subgroup of patients with CVD (HR, 0.2879; 95%CI, 0.0878-0.994; <em>P</em> <!-->&lt;<!--> <!-->.049; and HR, 0.1329; 95%CI, 0.024-0.6768; <em>P</em> <!-->=<!--> <!-->.014, respectively).</div></div><div><h3>Conclusions</h3><div>Initiation of combined therapy (SGLT2i and GLP1ra) vs monotherapy with SGLT2i or GLP1ra was associated with a lower risk of cancer mortality, mostly in diabetic patients with or without CVD. Although clinical trials are needed, these results might be explained by the complementary mechanisms of these drugs, including their antiproliferative, anti-inflammatory, and metabolic effects. Future clinical trials and mechanistic studies will clarify the possible role of these drugs in carcinogenesis.</div></div>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 3","pages":"Pages 218-228"},"PeriodicalIF":7.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141735252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}