Revista española de cardiología (English ed.)最新文献

{"title":"Vessel tortuosity: the understudied factor in percutaneous coronary intervention.","authors":"Íñigo Lozano, Ramón López-Palop, José Ramón Rumoroso","doi":"10.1016/j.rec.2025.02.017","DOIUrl":"https://doi.org/10.1016/j.rec.2025.02.017","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interactive effects of abdominal obesity and insulin resistance on cardiometabolic risk.","authors":"Mengyue Lin, Xiaocong Chen, Muli Wu, Jiaxin Xiao, Shaobin Li, Haoxian Tang, Xuerui Tan, Yequn Chen","doi":"10.1016/j.rec.2025.03.006","DOIUrl":"https://doi.org/10.1016/j.rec.2025.03.006","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Both abdominal obesity (AO) and insulin resistance (IR) are predictors of cardiometabolic disease (CMD). We aimed to evaluate the temporal relationship between AO and IR and their combined effect on CMD risk.</p><p><strong>Methods: </strong>A nationally representative cohort of 9234 participants was included, with a maximum follow-up of 9 years. The triglyceride-glucose (TyG) index was calculated as an indicator of IR, and AO was measured by waist circumference (WC). Cox regression was applied to evaluate the combined effect of AO and TyG on CMD risk, including hypertension, diabetes, heart disease, and stroke. A cross-lagged panel model was used to examine the temporal relationship. Multiplicative and additive interactions between AO and insulin resistance, as well as the mediating effect of TyG, were assessed.</p><p><strong>Results: </strong>Individuals concurrently with AO and higher TyG (≥ 8.6 [median]) had the highest risk of hypertension (HR,1.46; 95%CI, 1.25-1.69), diabetes (HR, 1.99; 95%CI, 1.65-2.41), and stroke (HR, 1.76; 95%CI, 1.22-1.94). A biological interaction between AO and IR on diabetes was observed, with the attributable proportion due to interaction being 29%. There was a bidirectional temporal relationship between WC and TyG, and the effect of WC on TyG was more prominent than vice versa. High TyG had a mediating effect on the association of AO with hypertension (19%), diabetes (25%), and stroke (24%).</p><p><strong>Conclusions: </strong>The findings reveal a temporal relationship between AO and IR, their combined effect on hypertension, diabetes, and stroke, and the mediating role of IR. Strategies simultaneously targeting both factors should be emphasized for the primary prevention of CMD.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Negative SA-VA difference during ventricular overdrive pacing of supraventricular tachycardia for the diagnosis of atrial tachycardia.","authors":"Raquel Adeliño, Víctor Bazán, Axel Sarrias, Jesús Jiménez-López, Júlia Aranyó, Felipe Bisbal, Joan F Andrés-Cordón, Julián Rodríguez-García, Pablo Jordán Marchite, Carlos Eduardo González-Matos, Roger Villuendas, Nuria Rivas-Gándara, Jesús Almendral","doi":"10.1016/j.rec.2025.03.005","DOIUrl":"https://doi.org/10.1016/j.rec.2025.03.005","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>The stimulus-atrial minus ventriculo-atrial interval (SA-VA difference) during ventricular overdrive pacing of a supraventricular tachycardia is used to differentiate atrioventricular reciprocating tachycardia (AVRT) from atrioventricular nodal re-entrant tachycardia (AVNRT), but positive values have always been reported. In atrial tachycardia, the SA conduction is unrelated to the tachycardia mechanism, allowing for negative SA-VA values. We postulated that a negative SA-VA may serve as a criterion for atrial tachycardia in patients with supraventricular tachycardia and ventricular overdrive pacing from the right ventricular apex.</p><p><strong>Methods: </strong>Multicenter data from ventricular overdrive pacing during atrial tachycardia (from 6 centers) and during AVRT and AVNRT (from 2 centers) were retrospectively and consecutively collected. The correct diagnosis was established using conventional criteria. The SA-VA difference was calculated for each case. The optimal SA-VA cut-off point for the diagnosis of atrial tachycardia was determined.</p><p><strong>Results: </strong>Out of 240 tachycardias analyzed, ventricular overdrive pacing succeeded in accelerating the atria to the pacing rate without tachycardia termination in 106 cases: 38 (36%) AVNRT, 33 (31%) AVRT, and 35 (33%) atrial tachycardias (all exhibiting long VA intervals). All atrial tachycardias had a negative SA-VA value, while all AVNRT and AVRT cases had positive SA-VA values. A SA-VA value lower than 0 ms was the best cutoff, with an area under the curve of 1 and 100% sensitivity and specificity for the diagnosis of atrial tachycardia.</p><p><strong>Conclusions: </strong>A negative SA-VA difference is a novel and accurate criterion for the diagnosis of atrial tachycardia with long VA intervals.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Edge-to-edge tricuspid valve repair and heart failure hospitalizations: the TRI-SPA registry.","authors":"Julio Echarte-Morales, Laura Sanchis, Dabit Arzamendi, Vanessa Moñivas, Fernando Carrasco-Chinchilla, Manuel Pan, Luis Nombela-Franco, Isaac Pascual, Tomás Benito-González, Ruth Pérez, Iván Gómez-Blázquez, Ignacio J Amat-Santos, Ignacio Cruz-González, Ángel Sánchez-Recalde, Ana Belén Cid Álvarez, Manuel Barreiro-Pérez, Pedro Cepas-Guillén, Chi Hion Li, María Del Trigo, José David Martínez-Carmona, Dolores Mesa, Patricia Mahía, Pablo Avanzas, André González-García, Xavier Freixa, Rodrigo Estévez-Loureiro","doi":"10.1016/j.rec.2025.02.015","DOIUrl":"https://doi.org/10.1016/j.rec.2025.02.015","url":null,"abstract":"<p><p>Introduction and objectives The prognostic impact of a history of heart failure hospitalizations (HFH) in patients undergoing transcatheter tricuspid edge-to-edge repair (T-TEER) has been scarcely studied. This study presents the results of the TRI-SPA registry, which includes data from 15 Spanish centers. Methods A multicenter, retrospective registry was conducted, including patients who underwent T-TEER between June 2020 and May 2023. Patients were classified into the 3 groups, based on the number of HFH in the 12 months prior to the procedure: no HFH, 1 HFH, and > 1 HFH (recurrent). The primary endpoint was all-cause mortality and HFH. Results Of the 262 patients included, 167 (63.7%) had no history of HFH, 60 (22.9%) had 1 HFH, and 35 (13.4%) had > 1 HFH. Patients with > 1 hospitalization had more comorbidities, higher surgical risk, and worse functional class; however, no significant differences were observed in the severity of tricuspid regurgitation either at baseline or after T-TEER. After a median follow-up of 365 [160-643] days, patients with recurrent HFH had higher rates of the composite outcome (9.9%, 16.7%, and 43.1%, respectively; P < .001), as well as higher mortality rates (P = .036) and HFH (P < .001). The number of HFH significantly decreased in the 12 months following T-TEER compared with the 12 months prior (P = .001). Conclusions Recurrent HFH within the 12 months prior to the procedure was associated with a higher risk of adverse clinical events during follow-up. T-TEER significantly reduced the number of hospitalizations during the follow-up period. Full English text available from: www.revespcardiol.org/en.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Juan Cosín Aguilar.","authors":"Enrique Asín Cardiel","doi":"10.1016/j.rec.2025.02.016","DOIUrl":"https://doi.org/10.1016/j.rec.2025.02.016","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Calcified nodules in the coronary arteries: systematic review on incidence and percutaneous coronary intervention outcomes.","authors":"Clara Fernández-Cordón, Emmanouil S Brilakis, Mario García-Gómez, Akash Jain, Marcelo Rodríguez, Carlos Cortés-Villar, Alberto Campo-Prieto, Ana Serrador, Hipólito Gutiérrez, Sara Blasco-Turrión, Luca Scorpiglione, Luis Llamas-Fernández, J Alberto San Román, Ignacio Jesús Amat Santos","doi":"10.1016/j.rec.2025.03.004","DOIUrl":"https://doi.org/10.1016/j.rec.2025.03.004","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Calcified nodules (CN) have been associated with higher complexity and worse outcomes after percutaneous coronary intervention (PCI) in both stable and unstable coronary disease. The aim of this systematic review was to summarize the current evidence on CN.</p><p><strong>Methods: </strong>Systematic review of published studies on the prevalence, clinical associations, and impact of CN on outcomes after PCI up to November 2024.</p><p><strong>Results: </strong>We identified 474 publications, of which 87 were included (all observational). CN were divided into 2 types: noneruptive CN (NECN), with an intact fibrous cap; and eruptive CN (ECN), with disruption of the fibrous cap with or without thrombus. The most common location was the right coronary artery (28%-71%). Angiography-based diagnostic sensitivity was low (18%-38%). Optical coherence tomography was preferred for type differentiation. The main clinical factors associated with CN were older age, diabetes mellitus, and chronic kidney disease. CN were considered the culprit lesion in 3% to 18% of acute coronary syndromes but were also present in up to 30% of nonculprit arteries. ECN were associated with more events at follow-up than NECN (20% vs 3.3% at 1 year). Post-PCI, CN were associated with lower minimum lumen area (MLA), higher rates of stent-edge dissection (44%-73%), malapposition (71%-96%), and underexpansion (60%-77%). ECN were associated with better acute results but worse long-term outcomes compared with NECN.</p><p><strong>Conclusions: </strong>CN are often present in acute coronary syndrome culprit and stable coronary lesions. Intracoronary imaging is essential for the diagnosis and differentiation of CN. CN are associated with worse outcomes after PCI, acutely and during follow-up.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pleomorphic rhabdomyosarcoma of the pulmonary artery with mediastinal invasion.","authors":"Víctor Manuel López-Espinosa, Isabel Navarro-Pelayo Torres, Juan Emilio Alcalá-López","doi":"10.1016/j.rec.2025.03.003","DOIUrl":"https://doi.org/10.1016/j.rec.2025.03.003","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of left bundle branch block on maximal functional capacity in asymptomatic individuals without structural heart disease.","authors":"Patricia Palau, Eloy Domínguez, Silvia Mínguez, Gonzalo Núñez, Enrique Santas, Celia García-Conejo, Iván de Amo, Paloma Marín, Cristina Flor, Laura López, Lucía Ortega, Isabel Gabaldón-Sánchez, Rafael de la Espriella, Juan Sanchis, Julio Núñez","doi":"10.1016/j.rec.2025.03.001","DOIUrl":"10.1016/j.rec.2025.03.001","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>In asymptomatic individuals, left bundle branch block (LBBB) is associated with an increased risk of cardiovascular events, but its impact on maximal functional capacity remains unclear. This study aimed to evaluate maximal aerobic capacity (peakVO₂) in asymptomatic adults with LBBB without structural heart disease and compare it to an age-, physical activity-, and sex-matched control population.</p><p><strong>Methods: </strong>This prospective case-control study included asymptomatic adults with isolated LBBB and matched controls. All participants underwent maximal cardiopulmonary exercise testing and echocardiography. The primary outcome was to compare peakVO₂ and percent predicted peakVO₂ (pp-peakVO₂) between LBBB and matched controls. Secondary outcomes included differences in left ventricular indexed end-diastolic volumes (iLVEDV) and left ventricular ejection fraction (LVEF). Multivariate linear mixed models were used to analyze primary and secondary outcomes.</p><p><strong>Results: </strong>A total of 162 participants (81 with LBBB and 81 controls) were included. The mean age was 65.7±10.2 years, and 106 participants (65.4%) were women. The mean pp-peakVO₂ and peakVO₂ were 93.6±16.9% and 19.9±6.4mL/kg/min, respectively. There were no significant differences in cardiovascular risk factors, NT-proBNP, or hemoglobin values between groups. Multivariate analysis showed that the presence of LBBB was associated with lower peakVO₂ (-3.3mL/kg/min, 95%CI,-4.6 to-2.1; P <.001) and pp-peakVO₂ (-17.2%; 95%CI, -22.1 to -11.9; P <.001). Regarding secondary endpoints, individuals with LBBB showed higher iLVEDV (+4.4mL/m², 95%CI, 1.3 to 7.6; P=.006) and lower LVEF (-2.8%, 95%CI, -4.3 to -1.2; P <.001) compared with controls.</p><p><strong>Conclusions: </strong>In this study, adults with isolated LBBB showed reduced maximal functional capacity compared with controls. Registered at ClinicalTrials.gov (NCT05643404).</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between DNA methylation at smoking-related loci and mortality in patients with peripheral arterial disease.","authors":"Lidia Marcos-García, Albert Clarà, Sonia Pérez-Cabezón, Manuel Miralles-Hernández, Roberto Elosua, Alina Velescu","doi":"10.1016/j.rec.2025.02.014","DOIUrl":"10.1016/j.rec.2025.02.014","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravenous acetazolamide in patients with acute heart failure and persistent volume overload.","authors":"Noelia Fernández Villa, Sergio Manzano Fernández, Miriam Gómez Molina, Iris Paula Garrido Bravo, Domingo Andrés Pascual Figal, Francisco José Pastor Pérez","doi":"10.1016/j.rec.2025.01.025","DOIUrl":"https://doi.org/10.1016/j.rec.2025.01.025","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}