Néstor Báez-Ferrer, Anas Waleed Al-Hayani-Al-Hantoosh, Pablo Avanzas, Alberto Domínguez-Rodríguez
{"title":"Prognostic value of the red cell distribution width-to-albumin ratio in patients with heart failure.","authors":"Néstor Báez-Ferrer, Anas Waleed Al-Hayani-Al-Hantoosh, Pablo Avanzas, Alberto Domínguez-Rodríguez","doi":"10.1016/j.rec.2026.03.010","DOIUrl":"https://doi.org/10.1016/j.rec.2026.03.010","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Escolà-Vergé, Philipp Mathé, Burcu Isler, Michele Bartoletti, Siegbert Rieg, Brigitte Lamy, Sara Grillo, Miguel Villamarín, Pierre Tattevin, Nuria Fernández-Hidalgo
{"title":"Management and follow-up of patients with infective endocarditis: an international cross-sectional survey.","authors":"Laura Escolà-Vergé, Philipp Mathé, Burcu Isler, Michele Bartoletti, Siegbert Rieg, Brigitte Lamy, Sara Grillo, Miguel Villamarín, Pierre Tattevin, Nuria Fernández-Hidalgo","doi":"10.1016/j.rec.2026.04.001","DOIUrl":"https://doi.org/10.1016/j.rec.2026.04.001","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>To describe international practices in the management and follow-up of infective endocarditis.</p><p><strong>Methods: </strong>We conducted an anonymous web-based survey between October 15 and November 15, 2025, disseminated through European Society for Clinical Microbiology and Infectious Diseases (ESCMID) study groups and national and international societies. The questionnaire comprised 7 sections covering endocarditis team and cardiac surgery availability, inpatient management, and follow-up. Responses were described and compared according to country income (chi-square or Fisher's exact test, P < .05).</p><p><strong>Results: </strong>In total, 298 respondents from 49 countries completed the survey. An onsite endocarditis team and onsite cardiac surgery were reported by 53% (159) and 67% (200) of respondents, respectively. In addition, 81% of respondents (242) stated that blood cultures were obtained until clearance of bacteremia, and 61% (183) indicated that echocardiography was performed during treatment. Postdischarge follow-up was mainly coordinated by infectious diseases specialists (70% of respondents, 207). Moreover, 56% of respondents (168) reported that a final echocardiogram was performed, and 25% (74) reported that post-treatment blood cultures were performed. Follow-up duration was up to 6 months for 56% of respondents (169) and > 6 months for 44% (129). Centers in high-income countries more frequently had an endocarditis team (138/218 [63%] vs 21/80 [26%]; P < .001), transesophageal echocardiography (210/218 [96%] vs 61/80 [76%]; P < .001), and positron emission tomography-computed tomography (175/218 [80%] vs 36/80 [45%]; P < .001) and performed serial blood cultures (186/218 [85%] vs 56/80 [70%]; P = .007) and post-treatment blood cultures (67/218 [31%] vs 7/80 [9%]; P < .001).</p><p><strong>Conclusions: </strong>Substantial variability exists in the organization, monitoring, and follow-up of endocarditis. Consensus-based and evidence-informed strategies are needed to harmonize care.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147821719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Myocardial late gadolinium enhancement and ICD decision-making: current evidence and open questions.","authors":"Raimondo Pittorru, Joan Llevadot, Ivo Roca-Luque","doi":"10.1016/j.rec.2026.03.008","DOIUrl":"https://doi.org/10.1016/j.rec.2026.03.008","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147784027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sergio Raposeiras-Roubín, Manuel Anguita, Roberto Latini, Alberto Domínguez-Rodríguez, José A Barrabés, Pedro L Sánchez, Filippo Ottani, Stuart Pocock, Ruth Owen, Pablo Cristobo, Sandra Gómez-Talavera, Lidia Staszewsky, Noemí Escalera, Felipe Fernández-Vázquez, Matteo Bianco, Óscar Prada-Delgado, Carlos Nicolás Pérez-García, Valentina Pelizzoni, Felipe Navarro, José-Ángel Pérez-Rivera, Gonzalo Martín-Gorria, Alfredo Vetrano, Valentín Fuster, Xavier Rosselló, Borja Ibáñez
{"title":"Beta-blockers after invasively managed STEMI vs NSTEMI without reduced ejection fraction: a prespecified analysis from the REBOOT trial.","authors":"Sergio Raposeiras-Roubín, Manuel Anguita, Roberto Latini, Alberto Domínguez-Rodríguez, José A Barrabés, Pedro L Sánchez, Filippo Ottani, Stuart Pocock, Ruth Owen, Pablo Cristobo, Sandra Gómez-Talavera, Lidia Staszewsky, Noemí Escalera, Felipe Fernández-Vázquez, Matteo Bianco, Óscar Prada-Delgado, Carlos Nicolás Pérez-García, Valentina Pelizzoni, Felipe Navarro, José-Ángel Pérez-Rivera, Gonzalo Martín-Gorria, Alfredo Vetrano, Valentín Fuster, Xavier Rosselló, Borja Ibáñez","doi":"10.1016/j.rec.2026.03.007","DOIUrl":"https://doi.org/10.1016/j.rec.2026.03.007","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Recent trials have questioned the clinical benefit of beta-blockers in post-myocardial infarction (MI) patients with preserved left ventricular ejection fraction (LVEF). However, differences in pathophysiology and risk profile between MI with and without ST-segment elevation (STEMI and NSTEMI) may influence the effect of beta-blockers.</p><p><strong>Methods: </strong>In this prespecified subgroup analysis of the REBOOT trial, which randomized invasively managed MI patients with LVEF > 40% to beta-blockers or control, we evaluated differences in long-term effects of the intervention between STEMI (n = 4296) and NSTEMI (n = 4142). The primary endpoint was a composite of all-cause death, reinfarction, or heart failure hospitalization over a median follow-up of 3.7 years.</p><p><strong>Results: </strong>The primary endpoint and its components occurred more frequently in NSTEMI than in STEMI. A significant interaction between MI type and beta-blocker allocation was observed (P = .027). Among STEMI patients, beta-blockers were associated with a higher incidence of the primary endpoint (HR, 1.27; 95%CI, 1.00-1.62), whereas NSTEMI patients assigned to beta-blockers showed no effect (HR, 0.89; 95%CI, 0.72-1.10). Notably, NSTEMI patients with mildly reduced LVEF (40% to 50%) on beta-blockers experienced significantly fewer events than controls.</p><p><strong>Conclusions: </strong>The absence of clear clinical benefit from beta-blockers in invasively managed MI patients with preserved LVEF was consistent across STEMI and NSTEMI. The observed interaction by infarct type is exploratory and should not be interpreted as definitive evidence of harm associated with beta-blocker therapy in patients with STEMI and preserved LVEF. NSTEMI patients with mildly reduced LVEF may benefit from beta-blockers, warranting further investigation. (ClinicalTrials.gov: NCT03596385).</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vaccination as a strategy for cardiovascular prevention: from European consensus to clinical practice in Spain.","authors":"Clara Bonanad, Miguel Caínzos-Achirica","doi":"10.1016/j.rec.2026.02.011","DOIUrl":"https://doi.org/10.1016/j.rec.2026.02.011","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147784243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia Playán-Escribano, Carlos Labrandero de Lera, Leticia Albert de la Torre, Alejandro Rodríguez-Ogando, Antonio Moreno-Galdó, Inmaculada Guillén Rodríguez, Anna Sabaté-Rotés, Amparo Moya-Bonora, Lina María Caicedo Cuenca, María Jesús Del Cerro
{"title":"Adapting the REVEAL Lite 2 score to the pediatric population through machine learning: insights from the REHIPED registry for pediatric pulmonary hypertension.","authors":"Julia Playán-Escribano, Carlos Labrandero de Lera, Leticia Albert de la Torre, Alejandro Rodríguez-Ogando, Antonio Moreno-Galdó, Inmaculada Guillén Rodríguez, Anna Sabaté-Rotés, Amparo Moya-Bonora, Lina María Caicedo Cuenca, María Jesús Del Cerro","doi":"10.1016/j.rec.2026.03.006","DOIUrl":"https://doi.org/10.1016/j.rec.2026.03.006","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Risk scores for pulmonary hypertension (PH) have been proven useful in adults. However, no risk score has been validated in pediatric populations. Our aim was to adapt the REVEAL Lite 2 score to pediatrics, including groups 1 (pulmonary arterial hypertension) and 3 (PH associated with lung diseases).</p><p><strong>Methods: </strong>We used data from the REHIPED, which is the PH registry of the Spanish Society of Pediatric Cardiology and Congenital Heart Disease. The registry also incorporates some Colombian centers. Patients in group 1 and group 3 were included. The score was derived using machine learning. The contribution of each variable and its cutoffs were identified through gradient boosting. The REVEAL Lite 2 variables were normalized and entered into the model, along with each patient's weight, sex, and age. Risk stratification into 3 categories (low, intermediate, and high risk) was performed.</p><p><strong>Results: </strong>A total of 420 children were analyzed. The final model included functional class, age at diagnosis, heart rate, weight-for-height percentile, systolic blood pressure, natriuretic peptides, weight-for-age percentile, and 6-minute walk test. The area under the curve was 0.82, with an estimated area under the curve of 0.73 on unseen data. The log-rank P value for differences in transplant-free survival among the 3 risk strata (low, intermediate, and high) was < .001. HR for intermediate risk vs low risk was 3.10 (95%CI, 1.02-9.40; P = .046), and HR for high risk vs low risk was 12.30 (95%CI, 4.42-34.25; P < .001).</p><p><strong>Conclusions: </strong>Our score adequately stratifies the risk of PH in the pediatric population, including infants, and is based on noninvasive variables.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147784022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucía Fernández Gassó, Elena Ruiz-Bravo, Luis Domínguez Gadea, Sara Quinones Garrido, Raúl Moreno, Gema Bonilla Hernán
{"title":"Bone scintigraphy as a marker of reversibility in hydroxychloroquine-induced cardiomyopathy.","authors":"Lucía Fernández Gassó, Elena Ruiz-Bravo, Luis Domínguez Gadea, Sara Quinones Garrido, Raúl Moreno, Gema Bonilla Hernán","doi":"10.1016/j.rec.2025.12.024","DOIUrl":"10.1016/j.rec.2025.12.024","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147624032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}