Miguel Morales-García, María Belén García-Ortega, José Pérez Del Palacio, Eduardo Moreno-Escobar, Diego Segura-Rodríguez, Rocío García-Orta
{"title":"Identification of novel biomarkers in ascending thoracic aortic diseases by untargeted high-resolution mass spectrometry-based metabolomics.","authors":"Miguel Morales-García, María Belén García-Ortega, José Pérez Del Palacio, Eduardo Moreno-Escobar, Diego Segura-Rodríguez, Rocío García-Orta","doi":"10.1016/j.rec.2025.02.011","DOIUrl":"10.1016/j.rec.2025.02.011","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zojaina Hernández Rojas, M Rosa Dalmau Llorca, Carina Aguilar Martín, Elisabet Castro Blanco, Manuel García-Goñi, Josep M Alegret
{"title":"Population-based analysis of the cost of direct oral anticoagulants versus vitamin K antagonists in nonvalvular atrial fibrillation.","authors":"Zojaina Hernández Rojas, M Rosa Dalmau Llorca, Carina Aguilar Martín, Elisabet Castro Blanco, Manuel García-Goñi, Josep M Alegret","doi":"10.1016/j.rec.2024.11.023","DOIUrl":"10.1016/j.rec.2024.11.023","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
José Antonio Fernández-Sánchez, Torcuato Garrido-Arroquia Jurado, Juan Manuel Serrano-Marcos, Francisco Villagran Ramírez, Rafael de la Chica Ruano, Laura Pertejo-Manzano
{"title":"Acute coronary syndrome due to scorpion sting: a case report from Spain.","authors":"José Antonio Fernández-Sánchez, Torcuato Garrido-Arroquia Jurado, Juan Manuel Serrano-Marcos, Francisco Villagran Ramírez, Rafael de la Chica Ruano, Laura Pertejo-Manzano","doi":"10.1016/j.rec.2025.01.023","DOIUrl":"10.1016/j.rec.2025.01.023","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raymond N Haddad, Ali Houeijeh, Ender Odemis, Jean-Benoit Thambo, Turkay Saritas, Ibrahim Ece, Clement Karsenty, Kaan Yildiz, Mete Han Kizilkaya, Sébastien Hascoet, Hojat Mortezaeian, Harun Terin, Mohammed Kasem, Zakhia Saliba, Nazmi Narin
{"title":"MIOS-MFO, a multicenter international observational study of the Lifetech KONAR-MF ventricular septal defect occluder in treating perimembranous ventricular septal defects.","authors":"Raymond N Haddad, Ali Houeijeh, Ender Odemis, Jean-Benoit Thambo, Turkay Saritas, Ibrahim Ece, Clement Karsenty, Kaan Yildiz, Mete Han Kizilkaya, Sébastien Hascoet, Hojat Mortezaeian, Harun Terin, Mohammed Kasem, Zakhia Saliba, Nazmi Narin","doi":"10.1016/j.rec.2025.02.010","DOIUrl":"https://doi.org/10.1016/j.rec.2025.02.010","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>The Lifetech KONAR-MF ventricular septal defect occluder (MFO) is increasingly used for transcatheter perimembranous ventricular septal defect (pmVSD) closure. We aim to collect real-world data on patient outcomes and MFO performance in pmVSD cases.</p><p><strong>Methods: </strong>This was a nonrandomized, retrospective, multicenter, postmarketing clinical follow-up study of pmVSD patients implanted with the MFO device between 2018 and 2023. The primary endpoint was 6-month composite clinical success, defined as technical success (successful implantation and device retention at the end of the procedure), closure success (trivial or no residual shunt), absence of serious adverse events at 30 days, and no device removal or reintervention. Secondary endpoints consisted of technical success, procedural success (technical success and less than moderate residual shunt), closure success (clinically insignificant or absent residual shunt), and safety.</p><p><strong>Results: </strong>Our cohort comprised 333 patients (51.4% male, 10.2% adults), with a median age of 4.6 [IQR, 2-10] years and a median weight of 17 [IQR, 11-32] kg. Baseline defect characteristics consisted of a left ventricular defect diameter of 8 [IQR, 7-10] mm, with 13.8% of patients having aortic valve regurgitation, 9.9% having an indirect Gerbode shunt, 10.5% having mild aortic valve prolapse, and 32.2% having subaortic rim deficiency. Closure via a retrograde approach was performed in 183 patients (55%). Technical success at procedure completion was 97.6%, and procedural success was 94.6%. Closure success at 6 months was 97.1%, while composite clinical success was 90.1%. Freedom from serious adverse events was 95.2% at 30 days. Freedom from device-related events was 96.8% at 6 months and 93.8% at 24 months. Risk factors for 6-month composite clinical failure were aortic valve prolapse (OR, 4.85; 95% CI, 2.07-11.39) and right ventricular defect diameter (OR, 1.41; 95% CI, 1.01-1.98).</p><p><strong>Conclusions: </strong>Transcatheter closure of pmVSD with the MFO device demonstrated feasibility, effectiveness, and safety in real-world settings.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan Sanchis, Pablo Avanzas, David Filgueiras-Rama, Pablo García-Pavía, Laura Sanchis
{"title":"Revista Española de Cardiología 2024.","authors":"Juan Sanchis, Pablo Avanzas, David Filgueiras-Rama, Pablo García-Pavía, Laura Sanchis","doi":"10.1016/j.rec.2025.01.022","DOIUrl":"10.1016/j.rec.2025.01.022","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan Alfonso Zamorano-Vargas, Mikel Izquierdo, Robinson Ramírez-Vélez
{"title":"Oxygen uptake kinetics during postexercise recovery are impaired in long COVID-19 patients: a cross-sectional study.","authors":"Juan Alfonso Zamorano-Vargas, Mikel Izquierdo, Robinson Ramírez-Vélez","doi":"10.1016/j.rec.2025.02.009","DOIUrl":"10.1016/j.rec.2025.02.009","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David Hong, Minseok Hong, Onyou Kim, Heayoung Shin, Minjung Bak, Darae Kim, Jihoon Kim, Ki Hong Choi, Eun Kyoung Kim, Joo Myung Lee, Jeong Hoon Yang, Sung-A Chang, Sung-Ji Park, Sang-Chol Lee, Seung Woo Park, Jin-Oh Choi
{"title":"Efficacy and safety of SGLT2 inhibitors in patients with heart failure according to kidney function: a systematic review and meta-analysis.","authors":"David Hong, Minseok Hong, Onyou Kim, Heayoung Shin, Minjung Bak, Darae Kim, Jihoon Kim, Ki Hong Choi, Eun Kyoung Kim, Joo Myung Lee, Jeong Hoon Yang, Sung-A Chang, Sung-Ji Park, Sang-Chol Lee, Seung Woo Park, Jin-Oh Choi","doi":"10.1016/j.rec.2025.02.007","DOIUrl":"10.1016/j.rec.2025.02.007","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>This study aimed to evaluate the efficacy and safety of sodium-glucose cotransporter 2 (SGLT2) inhibitors throughout the spectrum of kidney function in patients with heart failure (HF).</p><p><strong>Methods: </strong>This meta-analysis included randomized controlled trials comparing SGLT2 inhibitors with placebo in patients with HF stratified by renal function. Literature from inception to June 8, 2024 was searched. The primary outcome was a composite of cardiovascular death or HF events.</p><p><strong>Results: </strong>Five trials were identified, comprising 21 204 patients (10 605 in the SGLT2 inhibitor group and 10 599 in the placebo group) who were randomized and followed up for a weighted median duration of 1.8 years. When patients were classified by estimated glomerular filtration rate (eGFR) of 60mL/min/1.73 m<sup>2</sup>, SGLT2 inhibitors reduced the risk of the primary outcome irrespective of kidney function (RR, 0.81; 95%CI, 0.75-0.87; P<.01 for eGFR <60mL/min/1.73 m<sup>2</sup>; RR, 0.79; 95%CI, 0.72-0.87; P<.01 for eGFR≥ 60mL/min/1.73 m<sup>2</sup>; test for subgroup differences P=.75). The beneficial impact of SGLT2 inhibitors was consistently observed when patients were further subclassified by eGFR values of 20-30, 30-45, 45-60, and >60mL/min/1.73 m<sup>2</sup> (test for subgroup differences, P=.54). Early eGFR decline showed a differential impact with increased risk only in the placebo subgroup (RR, 1.30; 95%CI, 1.15-1.47; P<.01), but not in the SGLT2 inhibitor subgroup (RR, 0.99; 95%CI, 0.86-1.13; P=.84) (test for subgroup differences, P<.01).</p><p><strong>Conclusions: </strong>SGLT2 inhibitor therapy is safe and effective throughout the spectrum of kidney function and regardless of the initial decline in kidney function in patients with chronic HF. Registered at PROSPERO: CRD42024565218.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ignacio Fernández-Herrero, Iván Gómez-Blázquez, Fernando Sarnago-Cebada
{"title":"Reparación mitral percutánea a través de filtro de vena cava.","authors":"Ignacio Fernández-Herrero, Iván Gómez-Blázquez, Fernando Sarnago-Cebada","doi":"10.1016/j.rec.2025.01.020","DOIUrl":"https://doi.org/10.1016/j.rec.2025.01.020","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}