Francisco González-Vílchez, Luis Almenar-Bonet, Manuel Gómez-Bueno, María G Crespo-Leiro, Manuel Cobo-Belaustegui, Manuel Crespín-Crespín, Carlos Ortiz-Bautista, Juan F Delgado-Jiménez, Marta de Antonio-Ferrer, José Manuel Sobrino-Márquez, Miguel Llano-Cardenal, José Antonio Vázquez de Prada, Francisco Nistal-Herrera, Cristina Castrillo, Beatriz Díaz-Molina, Vanesa Alonso-Fernández, Cristina Fidalgo-Muñiz, Diego Rangel-Sousa, Antonio Grande-Trillo, Sonia Mirabet, Laura López, Alba Maestro, Laura Triguero, Isabel Zegrí, Clara Simón, Antonino Ginel, Marta Farrero-Torres, Ángeles Castells, Pedro Caravaca-Pérez, Eduard Solé, José González-Costello, Elena García-Romero, Carles Díez-López, Lorena Herrador-Galindo, Fernando de Frutos, Laia Rosenfeld, Silvia Ibáñez-Caballero, Cristina García-Rodríguez, Lorena Santulario, Pasqual Llongueras, Adolfo Villa-Arranz, Manuel Martínez-Sellés, Iago Sousa-Casasnova, Eduardo Zataraín-Nicolás, Zorba Blázquez-Bermejo, Javier Castrodeza-Calvo, María Jesús Valero-Masa, Jorge Martínez-Solano, Manuela Camino-López, Nuria Gil-Villanueva, Juan Miguel Gil-Jaurena, Raquel López-Viella, Soledad Martínez-Penadés, Julia Martínez-Solé, Víctor Donoso-Trenado, Manuel Anguita-Sánchez, María Ángeles Tejero Hernández, Gloria Heredia Campos, Javier Segovia-Cubero, Cristina Mitroi, Mercedes Rivas-Lasarte, Sara Lozano-Jiménez, Jose María Viéitez-Flórez, María Dolores García-Cosío, Laura Morán-Fernández, Javier González Martín, Irene Marco-Clement, Maria Jesús Paniagua-Martín, Eduardo Barge-Caballero, Gonzalo Barge-Caballero, David Couto-Mallón, Daniel Enríquez-Vázquez, Milena Antúnez-Ballesteros, Carlos Labrandero de Lera, Álvaro González-Rocafort, Inés Ponz de Antonio, Adriana Rodríguez-Chaverri, Luz Polo López, Luis de la Fuente-Galán, Javier Tobar-Ruiz, Iris P Garrido-Bravo, Francisco J Pastor-Pérez, Domingo A Pascual-Figal, Teresa Blasco-Peiró, Ana Pórtoles-Ocampo, Ana Marcén-Mirabete, Gregorio Rábago-Juan-Aracil, Rebeca Manrique-Antón, Leticia Jimeno-San Martín, Antonio García-Quintana, María Del Val Groba-Marco, Mario Galván-Ruiz, Miguel Fernández de Sanmamed-Girón, Paola Dolader, Ferrán Gran-Ipiña
{"title":"Spanish heart transplant registry. 36th official report of the Heart Failure Association of the Spanish Society of Cardiology.","authors":"Francisco González-Vílchez, Luis Almenar-Bonet, Manuel Gómez-Bueno, María G Crespo-Leiro, Manuel Cobo-Belaustegui, Manuel Crespín-Crespín, Carlos Ortiz-Bautista, Juan F Delgado-Jiménez, Marta de Antonio-Ferrer, José Manuel Sobrino-Márquez, Miguel Llano-Cardenal, José Antonio Vázquez de Prada, Francisco Nistal-Herrera, Cristina Castrillo, Beatriz Díaz-Molina, Vanesa Alonso-Fernández, Cristina Fidalgo-Muñiz, Diego Rangel-Sousa, Antonio Grande-Trillo, Sonia Mirabet, Laura López, Alba Maestro, Laura Triguero, Isabel Zegrí, Clara Simón, Antonino Ginel, Marta Farrero-Torres, Ángeles Castells, Pedro Caravaca-Pérez, Eduard Solé, José González-Costello, Elena García-Romero, Carles Díez-López, Lorena Herrador-Galindo, Fernando de Frutos, Laia Rosenfeld, Silvia Ibáñez-Caballero, Cristina García-Rodríguez, Lorena Santulario, Pasqual Llongueras, Adolfo Villa-Arranz, Manuel Martínez-Sellés, Iago Sousa-Casasnova, Eduardo Zataraín-Nicolás, Zorba Blázquez-Bermejo, Javier Castrodeza-Calvo, María Jesús Valero-Masa, Jorge Martínez-Solano, Manuela Camino-López, Nuria Gil-Villanueva, Juan Miguel Gil-Jaurena, Raquel López-Viella, Soledad Martínez-Penadés, Julia Martínez-Solé, Víctor Donoso-Trenado, Manuel Anguita-Sánchez, María Ángeles Tejero Hernández, Gloria Heredia Campos, Javier Segovia-Cubero, Cristina Mitroi, Mercedes Rivas-Lasarte, Sara Lozano-Jiménez, Jose María Viéitez-Flórez, María Dolores García-Cosío, Laura Morán-Fernández, Javier González Martín, Irene Marco-Clement, Maria Jesús Paniagua-Martín, Eduardo Barge-Caballero, Gonzalo Barge-Caballero, David Couto-Mallón, Daniel Enríquez-Vázquez, Milena Antúnez-Ballesteros, Carlos Labrandero de Lera, Álvaro González-Rocafort, Inés Ponz de Antonio, Adriana Rodríguez-Chaverri, Luz Polo López, Luis de la Fuente-Galán, Javier Tobar-Ruiz, Iris P Garrido-Bravo, Francisco J Pastor-Pérez, Domingo A Pascual-Figal, Teresa Blasco-Peiró, Ana Pórtoles-Ocampo, Ana Marcén-Mirabete, Gregorio Rábago-Juan-Aracil, Rebeca Manrique-Antón, Leticia Jimeno-San Martín, Antonio García-Quintana, María Del Val Groba-Marco, Mario Galván-Ruiz, Miguel Fernández de Sanmamed-Girón, Paola Dolader, Ferrán Gran-Ipiña","doi":"10.1016/j.rec.2025.04.011","DOIUrl":"10.1016/j.rec.2025.04.011","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>This report presents updated data on heart transplants in Spain, including procedures carried out in 2024. It reviews trends over the past decade (2015-2024) in donor and recipient characteristics, surgical techniques, immunosuppression strategies, and survival rates.</p><p><strong>Methods: </strong>Data were drawn from the Spanish heart transplant registry, which is updated annually. The analysis includes 347 transplants performed in 2024, as well as procedures from 2015 to 2023 (n=2721).</p><p><strong>Results: </strong>In 2024, the number of heart transplants increased by 6.8% compared with 2023. There were no significant changes in recipient age or sex, but the proportion of urgent transplants rose to 47.0%. Use of circulatory support devices increased, particularly extracorporeal membrane oxygenation. The average donor age showed a slight increase in 2024, although the long-term trend remained downward. Donation after circulatory death accounted for 29.1% of transplants in 2024. One-year survival rates improved, reaching 85.2% for transplants performed between 2021 and 2023.</p><p><strong>Conclusions: </strong>The number of heart transplants continued to grow, nearing historic highs, largely due to the expansion of donation after circulatory death. Improved 1-year survival reflects the maturity of transplant programs, advances in surgical and medical management, and better pretransplant conditions in recipients.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144498276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan Manuel Serrano-Marcos, Víctor Manuel López-Espinosa, Míriam Cantero-Campos
{"title":"Uncommon cardiac involvement in metastatic osteosarcoma.","authors":"Juan Manuel Serrano-Marcos, Víctor Manuel López-Espinosa, Míriam Cantero-Campos","doi":"10.1016/j.rec.2025.06.004","DOIUrl":"10.1016/j.rec.2025.06.004","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144498277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Filipe A Gonzalez, Jacobo Bacariza, João Leote, Ana Rita Varudo, Ana G Almeida, Luís R Lopes
{"title":"Analysis of cardiomyopathy-associated genes in septic cardiomyopathy.","authors":"Filipe A Gonzalez, Jacobo Bacariza, João Leote, Ana Rita Varudo, Ana G Almeida, Luís R Lopes","doi":"10.1016/j.rec.2025.06.002","DOIUrl":"10.1016/j.rec.2025.06.002","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fontan completion in adulthood in patients with a functional single ventricle.","authors":"Tianyu Chen, Jianzheng Cen, Shusheng Wen, Jimei Chen, Xiaobing Liu, Jian Zhuang","doi":"10.1016/j.rec.2025.06.003","DOIUrl":"10.1016/j.rec.2025.06.003","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction in article by SEC Working Group and SEC Guidelines Committee “Comments on the 2024 ESC guidelines for the management of elevated blood pressure and hypertension”, Rev Esp Cardiol. 2025;78:296-300","authors":"","doi":"10.1016/j.rec.2025.05.006","DOIUrl":"10.1016/j.rec.2025.05.006","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 8","pages":"Page 752"},"PeriodicalIF":7.2,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144713123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Álvaro Montes Muñiz, Alberto Cecconi, Luis Jesús Jiménez-Borreguero
{"title":"Refining the assessment of excessive left ventricular trabeculation.","authors":"Álvaro Montes Muñiz, Alberto Cecconi, Luis Jesús Jiménez-Borreguero","doi":"10.1016/j.rec.2025.04.010","DOIUrl":"10.1016/j.rec.2025.04.010","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144250108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ramona Ghenghea, Clement Karsenty, Pierrick Pyra, Aitor Guitarte, Yves Dulac, Paul Vignaud, Philippe Acar, Khaled Hadeed
{"title":"Assessment of tricuspid annulus geometry in children with congenital heart disease using three-dimensional echocardiography.","authors":"Ramona Ghenghea, Clement Karsenty, Pierrick Pyra, Aitor Guitarte, Yves Dulac, Paul Vignaud, Philippe Acar, Khaled Hadeed","doi":"10.1016/j.rec.2025.06.001","DOIUrl":"10.1016/j.rec.2025.06.001","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>The tricuspid annulus (TA) in congenital heart diseases (CHD) may undergo significant changes in size, shape, and function due to hemodynamic overload. This study aimed to compare TA remodeling in children with CHD based on the type of right ventricle (RV) overload, using three-dimensional transthoracic echocardiography (3D-TTE).</p><p><strong>Methods: </strong>This prospective case-control study included children with CHD who were divided into 2 groups based on the type of RV overload. Using 3D-TTE, we assessed the dimensions of the right chambers, the surface area, and the tenting volume of the TA, and analyzed the correlation among these measurements.</p><p><strong>Results: </strong>A total of 90 patients were enrolled: 30 with pretricuspid overload (atrial septal defect and partial anomalous pulmonary venous connection), 33 with posttricuspid overload (pulmonary regurgitation after RV outflow tract surgery), and 27 healthy controls. 3D TA surface area was larger in the pretricuspid group than in the posttricuspid group (median 6.60cm<sup>2</sup>/m<sup>2</sup> vs 5.16cm<sup>2</sup>/m<sup>2</sup>; P=.01) and was correlated with right atrial (RA) volume (P=.0001, r=0.66) and RA surface area (P<.0001, r=0.74) in the pretricuspid group. The tenting volume was greater in the posttricuspid group than in the control group. The 3D TA surface area and tenting volume were not correlated with RV end-diastolic volume.</p><p><strong>Conclusions: </strong>3D modeling of the TA using 3D-TTE is feasible and provides insights into TA remodeling in different RV overload conditions. RA volume and surface area are key determinants of TA size, which could have an impact on therapeutic strategies in patients with tricuspid regurgitation.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144250106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jorge Sanz Sánchez, José Antonio Sorolla Romero, Jean Paul Vílchez Tschischke, Carles Fonfria, Ignacio J Amat Santos, José Luis Díez Gil
{"title":"Commissural alignment with the Allegra transcatheter aortic bioprosthesis.","authors":"Jorge Sanz Sánchez, José Antonio Sorolla Romero, Jean Paul Vílchez Tschischke, Carles Fonfria, Ignacio J Amat Santos, José Luis Díez Gil","doi":"10.1016/j.rec.2025.05.011","DOIUrl":"10.1016/j.rec.2025.05.011","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144250107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julián Rodríguez-García, Rafel Ramos, Anna Ponjoan, Jordi Blanch, Miguel Cainzos-Achirica, Paolo D Dallaglio, Rodolfo San Antonio, Marcos Rodríguez-García, Jordi Mercé, Valentina Faga, Javier Sanaú, Ismael Almonte, Jesús Rodríguez-Silva, Josep Comín-Colet, Ignasi Anguera, Andrea Di Marco
{"title":"Association between atrial fibrillation and dementia in a large population-based study in southern Europe.","authors":"Julián Rodríguez-García, Rafel Ramos, Anna Ponjoan, Jordi Blanch, Miguel Cainzos-Achirica, Paolo D Dallaglio, Rodolfo San Antonio, Marcos Rodríguez-García, Jordi Mercé, Valentina Faga, Javier Sanaú, Ismael Almonte, Jesús Rodríguez-Silva, Josep Comín-Colet, Ignasi Anguera, Andrea Di Marco","doi":"10.1016/j.rec.2025.05.009","DOIUrl":"10.1016/j.rec.2025.05.009","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>The association between atrial fibrillation (AF) and dementia remains debated, and data from Mediterranean populations are scarce. We aimed to evaluate the relationship between AF and dementia in a large Catalan cohort, with a particular focus on identifying subgroups with the strongest associations.</p><p><strong>Methods: </strong>We conducted a population-based observational study including individuals aged ≥45 years without prior diagnosis of dementia. Data were obtained from the System for the Development of Research in Primary Care, which covers more than 80% of the Catalan population. Dementia was identified using ICD-10-CM codes and prescription records. Early-onset dementia (EOD) was defined as diagnosis before age 65 years. Participants were followed up from 2009 to 2021. Cox regression models were used to identify predictors of incident dementia.</p><p><strong>Results: </strong>A total of 2 520 839 individuals were included (mean follow-up: 13 years), of whom 79820 (3.25%) had AF at baseline. On univariate analysis, AF was a strong predictor of dementia (HR, 3.39; P<.001). However, after multivariable adjustment, the association was modest (HR, 1.04; P<.001). AF was a stronger independent predictor in individuals aged <70 years (HR, 1.21; P<.001), whereas the association was not significant in those aged ≥70. The strongest association was observed for EOD (HR, 1.36; P<.001). All associations remained consistent in analyses restricted to individuals without prior stroke.</p><p><strong>Conclusions: </strong>In a large Mediterranean cohort, AF was independently associated with a modest increase in dementia risk, regardless of stroke. This association was stronger in younger individuals and in EOD. These findings highlight the need for studies assessing the impact of early identification and management of AF on dementia incidence in younger populations.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emilio Alfonso Rodríguez, Josep Gómez-Lara, Ramón López-Palop, Enrique Gutiérrez, Luis Renier Goncalves Ramírez, José Valencia, Alfonso Jurado-Román, Juan Gabriel Córdoba Soriano, Antonio Gómez-Menchero, Estefanía Fernández-Peregrina, Carlos Cortés, Paula Tejedor, Raúl Millan, Guillermo Sánchez-Elvira, Tamara García-Camarero, José Antonio Linares Vicente, Eva Rúmiz, Rosa María Cardenal Piris, Irene Elizondo Rua, Jean Paul Vilchez, Salvatore Brugaletta, Lara Fuentes, Ana Marcano, Pilar Carrillo, Álvaro Gabaldón, Armando Pérez de Prado, Joan Antoni Gómez-Hospital
{"title":"Diagnostic accuracy of quantitative flow ratio for nonculprit intermediate lesions in patients with ST-segment elevation myocardial infarction.","authors":"Emilio Alfonso Rodríguez, Josep Gómez-Lara, Ramón López-Palop, Enrique Gutiérrez, Luis Renier Goncalves Ramírez, José Valencia, Alfonso Jurado-Román, Juan Gabriel Córdoba Soriano, Antonio Gómez-Menchero, Estefanía Fernández-Peregrina, Carlos Cortés, Paula Tejedor, Raúl Millan, Guillermo Sánchez-Elvira, Tamara García-Camarero, José Antonio Linares Vicente, Eva Rúmiz, Rosa María Cardenal Piris, Irene Elizondo Rua, Jean Paul Vilchez, Salvatore Brugaletta, Lara Fuentes, Ana Marcano, Pilar Carrillo, Álvaro Gabaldón, Armando Pérez de Prado, Joan Antoni Gómez-Hospital","doi":"10.1016/j.rec.2025.05.010","DOIUrl":"10.1016/j.rec.2025.05.010","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>The reliability of quantitative flow ratio (QFR) has been questioned. Our aim was to evaluate the diagnostic accuracy of QFR in intermediate nonculprit lesions during the index ST-segment elevation myocardial infarction (STEMI) procedure compared with positive pressure wire-based fractional flow reserve (FFR ≤0.80) in a staged procedure.</p><p><strong>Methods: </strong>This was a substudy of the multicenter, controlled, and randomized VULNERABLE trial, including 428 intermediate nonculprit lesions from 388 consecutive STEMI patients undergoing FFR assessment in a staged procedure between 1 and 60 days. Off-line QFR analyses were performed during both the index and staged procedures. The primary objective was to assess the diagnostic accuracy of index QFR compared with staged positive FFR.</p><p><strong>Results: </strong>Angiographic vessel diameter (2.80±0.59 vs 2.91±0.57mm; P<.01), stenosis severity (51.33±8.04% vs 50.54±7.63%; P=.053), and QFR values (0.85±0.09 vs 0.86±0.09; P=.120) showed minimal changes between the index and staged procedures. Moderate concordance was observed between index QFR and staged FFR (kappa index=0.629; intraclass correlation coefficient=0.641). The diagnostic accuracy of index QFR for predicting positive FFR was good (area under the curve=0.825). An index QFR cutoff ≤0.80 showed moderate sensitivity (72%) and excellent specificity (91%). An index QFR ≤0.87 achieved a sensitivity of 86% for detecting lesions with positive FFR, with 55% of lesions presenting QFR ≤0.87 at the index procedure.</p><p><strong>Conclusions: </strong>Index QFR demonstrated good diagnostic accuracy for identifying lesions with positive FFR in a staged procedure. However, an index QFR cutoff value of ≤0.80 showed moderate sensitivity and may underdiagnose approximately 3 out of 10 lesions with positive FFR. An index QFR ≤0.87 provided higher sensitivity and may help avoid invasive (staged) procedures in many patients.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}