Sonia Antoñana-Ugalde, Ana García-Martín, Luisa Salido-Tahoces, Ángel Sánchez-Recalde, José Luis Zamorano-Gómez, Covadonga Fernández-Golfín Lobán
{"title":"Reverse ventricular remodeling after transcatheter aortic valve implantation in pure aortic regurgitation.","authors":"Sonia Antoñana-Ugalde, Ana García-Martín, Luisa Salido-Tahoces, Ángel Sánchez-Recalde, José Luis Zamorano-Gómez, Covadonga Fernández-Golfín Lobán","doi":"10.1016/j.rec.2024.12.016","DOIUrl":"https://doi.org/10.1016/j.rec.2024.12.016","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"\"False positive\" stress CMR in a patient with cardiac amyloidosis.","authors":"Marcos Ferrández-Escarabajal, Gina LaRocca","doi":"10.1016/j.rec.2025.02.005","DOIUrl":"https://doi.org/10.1016/j.rec.2025.02.005","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tratamiento percutáneo de un hematoma septal masivo.","authors":"Álvaro Álvarez, María Tamargo, Gregorio Cuerpo","doi":"10.1016/j.rec.2024.11.020","DOIUrl":"https://doi.org/10.1016/j.rec.2024.11.020","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Tébar-Márquez, Alejandro Díez-Vidal, Yale Tung-Chen
{"title":"Antithrombotic therapy after percutaneous left atrial appendage closure: should it be the same for everyone?","authors":"Daniel Tébar-Márquez, Alejandro Díez-Vidal, Yale Tung-Chen","doi":"10.1016/j.rec.2024.12.015","DOIUrl":"https://doi.org/10.1016/j.rec.2024.12.015","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luigi P Badano, Marco Penso, Michele Tomaselli, Kyu Kim, Alexandra Clement, Noela Radu, Geu-Ru Hong, Diana R Hădăreanu, Alexandra Buta, Caterina Delcea, Samantha Fisicaro, Gianfranco Parati, Chi Young Shim, Denisa Muraru
{"title":"Advanced echocardiography and cluster analysis to identify secondary tricuspid regurgitation phenogroups at different risk.","authors":"Luigi P Badano, Marco Penso, Michele Tomaselli, Kyu Kim, Alexandra Clement, Noela Radu, Geu-Ru Hong, Diana R Hădăreanu, Alexandra Buta, Caterina Delcea, Samantha Fisicaro, Gianfranco Parati, Chi Young Shim, Denisa Muraru","doi":"10.1016/j.rec.2025.02.004","DOIUrl":"https://doi.org/10.1016/j.rec.2025.02.004","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Significant secondary tricuspid regurgitation (STR) is associated with poor prognosis, but its heterogeneity makes predicting patient outcomes challenging. Our objective was to identify STR prognostic phenogroups.</p><p><strong>Methods: </strong>We analyzed 758 patients with moderate-to-severe STR: 558 (74 ± 14 years, 55% women) in the derivation cohort and 200 (73 ± 12 years, 60% women) in the external validation cohort. The primary endpoint was a composite of heart failure hospitalization and all-cause mortality.</p><p><strong>Results: </strong>We identified 3 phenogroups. The low-risk phenogroup (2-year event-free survival 80%, 95%CI, 74%-87%) had moderate STR, preserved right ventricular (RV) size and function, and a moderately dilated but normally functioning right atrium. The intermediate-risk phenogroup (HR, 2.20; 95%CI, 1.44-3.37; P < .001) included older patients with severe STR, and a mildly dilated but uncoupled RV. The high-risk phenogroup (HR, 4.67; 95%CI, 3.20-6.82; P < .001) included younger patients with massive-to-torrential tricuspid regurgitation, as well as severely dilated and dysfunctional RV and right atrium. Multivariable analysis confirmed the clustering as independently associated with the composite endpoint (HR, 1.40; 95%CI, 1.13-1.70; P = .002). A supervised machine learning model, developed to assist clinicians in assigning patients to the 3 phenogroups, demonstrated excellent performance both in the derivation cohort (accuracy = 0.91, precision = 0.91, recall = 0.91, and F1 score = 0.91) and in the validation cohort (accuracy = 0.80, precision = 0.78, recall = 0.78, and F1 score = 0.77).</p><p><strong>Conclusions: </strong>The unsupervised cluster analysis identified 3 risk phenogroups, which could assist clinicians in developing more personalized treatment and follow-up strategies for STR patients.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jose Antonio Esteban-Chapel, Juan Antonio Franco-Peláez, Alvaro Aceña
{"title":"Antiplatelet therapy for primary prevention of nonsignificant coronary lesions.","authors":"Jose Antonio Esteban-Chapel, Juan Antonio Franco-Peláez, Alvaro Aceña","doi":"10.1016/j.rec.2025.01.019","DOIUrl":"https://doi.org/10.1016/j.rec.2025.01.019","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jens Wiebe, Constantin Kuna, Tareq Ibrahim, Sebastian Kufner, Isabella Hintz, Paul Justenhoven, Thorsten Kessler, Heribert Schunkert, Marco Valgimigli, Gert Richardt, Jola Bresha, Karl-Ludwig Laugwitz, Adnan Kastrati, Salvatore Cassese
{"title":"Ten-year clinical outcomes after left main coronary artery stenting with new-generation or early-generation DES.","authors":"Jens Wiebe, Constantin Kuna, Tareq Ibrahim, Sebastian Kufner, Isabella Hintz, Paul Justenhoven, Thorsten Kessler, Heribert Schunkert, Marco Valgimigli, Gert Richardt, Jola Bresha, Karl-Ludwig Laugwitz, Adnan Kastrati, Salvatore Cassese","doi":"10.1016/j.rec.2025.02.003","DOIUrl":"10.1016/j.rec.2025.02.003","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Long-term data after stenting of the left main coronary artery (LMCA) are scarce, especially regarding new-generation drug-eluting stents (DES). This analysis aimed to describe the 10-year clinical outcomes of patients who underwent percutaneous coronary intervention with different DES generations for LMCA disease.</p><p><strong>Methods: </strong>Individual patient data from the randomized controlled ISAR-LEFT MAIN and ISAR-LEFT MAIN 2 trials were pooled and 10-year clinical follow-up was obtained. The Kaplan-Meier method was used to calculate event rates. The main endpoints of interest for this analysis were all-cause mortality, myocardial infarction, target lesion revascularization and definite stent thrombosis.</p><p><strong>Results: </strong>A total of 1257 patients were included in this analysis, of which 650 patients were treated with new-generation DES and 607 with early-generation DES. At 10 years, the mortality rate was more than 40% in both groups. After statistical adjustment, 10-year mortality was significantly reduced in patients treated with new-generation DES compared with those treated with early-generation DES (HR<sub>adj</sub>, 0.78; 95%CI, 0.62-0.97). After 10 years, the risk of myocardial infarction (HR<sub>adj</sub>, 0.43; 95%CI, 0.23-0.80), target lesion revascularization (HR<sub>adj</sub>, 0.66; 95%CI, 0.49-0.89), and definite stent thrombosis (HR<sub>adj</sub>, 0.13, 95%CI, 0.04-0.49) was significantly reduced by new-generation DES compared with early-generation DES.</p><p><strong>Conclusions: </strong>Patients undergoing percutaneous coronary intervention for LMCA disease have high 10-year mortality regardless of DES generation. The use of new-generation DES in patients with LMCA disease is associated with improved long-term clinical outcomes compared with early-generation DES.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Danielle Medina-Hernández, Carlos Galán-Arriola, Javier Sánchez-González, Julien Ochala, Borja Ibáñez
{"title":"Anthracycline cardiotoxicity is associated with aberrant cardiac myosin energetics.","authors":"Danielle Medina-Hernández, Carlos Galán-Arriola, Javier Sánchez-González, Julien Ochala, Borja Ibáñez","doi":"10.1016/j.rec.2025.02.001","DOIUrl":"10.1016/j.rec.2025.02.001","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martín Negreira-Caamaño, Felipe Díez-Delhoyo, Pedro Cepas-Guillén, María Thiscal López-Lluva, Alfonso Jurado-Román, Pablo Bazal-Chacón, Iván Olavarri-Miguel, Ane Elorriaga, Ricardo Rivera-López, Emilio Blanco-López, Pablo Díez-Villanueva
{"title":"Prognostic impact of atrial fibrillation and atrial flutter in patients with non-ST-segment elevation acute coronary syndrome.","authors":"Martín Negreira-Caamaño, Felipe Díez-Delhoyo, Pedro Cepas-Guillén, María Thiscal López-Lluva, Alfonso Jurado-Román, Pablo Bazal-Chacón, Iván Olavarri-Miguel, Ane Elorriaga, Ricardo Rivera-López, Emilio Blanco-López, Pablo Díez-Villanueva","doi":"10.1016/j.rec.2025.02.002","DOIUrl":"10.1016/j.rec.2025.02.002","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Arrhythmias such as atrial fibrillation and atrial flutter (AF/AFl) complicate the management of patients with non-ST-segment elevation acute coronary syndrome (NSTEACS). The aim of this study was to analyze the prognostic impact of AF/AFl in this clinical setting.</p><p><strong>Methods: </strong>The IMPACT-TIMING-GO is a prospective, multicenter registry that enrolled patients with NSTEACS undergoing invasive management. In this subanalysis, patients were categorized based on the presence of AF/AFl (either pre-existing or occurring during admission). Clinical management and complications were assessed both during hospitalization (using a composite endpoint of death, renal failure, ventricular arrhythmias, delirium, new infarction, mechanical complications, and major bleeding) and after 1 year of follow-up (using a composite endpoint of death, cardiovascular admissions, and major bleeding).</p><p><strong>Results: </strong>A total of 1020 patients (mean age, 66.8±12.7 years; 23.5% women) were included. Of these, 79 (7.7%) had prior AF/AFl, and 37 (3.6%) developed de novo AF/AFl during admission. Patients with AF/AFl were older and had a higher comorbidity burden, with de novo AF/AFl being associated with greater clinical severity. After multivariate adjustment, only de novo AF/AFl, and not previous AF/AFl, was independently associated with the composite endpoint of in-hospital complications (OR, 5.12; 95%CI, 2.30-11.43; P <.001 vs OR, 1.70, 95%CI, 0.91-3.58; P=.166) and adverse events at 1 year (HR, 1.95; 95%CI, 1.02-3.76; P=.045 vs HR, 1.02, 95%CI, 0.55-5.86; P=.957).</p><p><strong>Conclusions: </strong>In patients with NSTEACS, de novo AF/AFl is independently associated with higher rates of both in-hospital and follow-up complications.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chi-Hion Pedro Li, Lluís Asmarats, Albert Massó van Roessel, Helena Capellades, Xavier Millán, Dabit Arzamendi
{"title":"Predictability and device tilting in edge-to-edge mitral valve repair.","authors":"Chi-Hion Pedro Li, Lluís Asmarats, Albert Massó van Roessel, Helena Capellades, Xavier Millán, Dabit Arzamendi","doi":"10.1016/j.rec.2025.01.017","DOIUrl":"10.1016/j.rec.2025.01.017","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}