Revista española de cardiología (English ed.)最新文献

{"title":"Refining the assessment of excessive left ventricular trabeculation.","authors":"Álvaro Montes Muñiz, Alberto Cecconi, Luis Jesús Jiménez-Borreguero","doi":"10.1016/j.rec.2025.04.010","DOIUrl":"10.1016/j.rec.2025.04.010","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144250108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of tricuspid annulus geometry in children with congenital heart disease using three-dimensional echocardiography.","authors":"Ramona Ghenghea, Clement Karsenty, Pierrick Pyra, Aitor Guitarte, Yves Dulac, Paul Vignaud, Philippe Acar, Khaled Hadeed","doi":"10.1016/j.rec.2025.06.001","DOIUrl":"10.1016/j.rec.2025.06.001","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>The tricuspid annulus (TA) in congenital heart diseases (CHD) may undergo significant changes in size, shape, and function due to hemodynamic overload. This study aimed to compare TA remodeling in children with CHD based on the type of right ventricle (RV) overload, using three-dimensional transthoracic echocardiography (3D-TTE).</p><p><strong>Methods: </strong>This prospective case-control study included children with CHD who were divided into 2 groups based on the type of RV overload. Using 3D-TTE, we assessed the dimensions of the right chambers, the surface area, and the tenting volume of the TA, and analyzed the correlation among these measurements.</p><p><strong>Results: </strong>A total of 90 patients were enrolled: 30 with pretricuspid overload (atrial septal defect and partial anomalous pulmonary venous connection), 33 with posttricuspid overload (pulmonary regurgitation after RV outflow tract surgery), and 27 healthy controls. 3D TA surface area was larger in the pretricuspid group than in the posttricuspid group (median 6.60cm²/m² vs 5.16cm²/m²; P=.01) and was correlated with right atrial (RA) volume (P=.0001, r=0.66) and RA surface area (P<.0001, r=0.74) in the pretricuspid group. The tenting volume was greater in the posttricuspid group than in the control group. The 3D TA surface area and tenting volume were not correlated with RV end-diastolic volume.</p><p><strong>Conclusions: </strong>3D modeling of the TA using 3D-TTE is feasible and provides insights into TA remodeling in different RV overload conditions. RA volume and surface area are key determinants of TA size, which could have an impact on therapeutic strategies in patients with tricuspid regurgitation.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144250106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commissural alignment with the Allegra transcatheter aortic bioprosthesis.","authors":"Jorge Sanz Sánchez, José Antonio Sorolla Romero, Jean Paul Vílchez Tschischke, Carles Fonfria, Ignacio J Amat Santos, José Luis Díez Gil","doi":"10.1016/j.rec.2025.05.011","DOIUrl":"10.1016/j.rec.2025.05.011","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144250107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between atrial fibrillation and dementia in a large population-based study in southern Europe.","authors":"Julián Rodríguez-García, Rafel Ramos, Anna Ponjoan, Jordi Blanch, Miguel Cainzos-Achirica, Paolo D Dallaglio, Rodolfo San Antonio, Marcos Rodríguez-García, Jordi Mercé, Valentina Faga, Javier Sanaú, Ismael Almonte, Jesús Rodríguez-Silva, Josep Comín-Colet, Ignasi Anguera, Andrea Di Marco","doi":"10.1016/j.rec.2025.05.009","DOIUrl":"10.1016/j.rec.2025.05.009","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>The association between atrial fibrillation (AF) and dementia remains debated, and data from Mediterranean populations are scarce. We aimed to evaluate the relationship between AF and dementia in a large Catalan cohort, with a particular focus on identifying subgroups with the strongest associations.</p><p><strong>Methods: </strong>We conducted a population-based observational study including individuals aged ≥45 years without prior diagnosis of dementia. Data were obtained from the System for the Development of Research in Primary Care, which covers more than 80% of the Catalan population. Dementia was identified using ICD-10-CM codes and prescription records. Early-onset dementia (EOD) was defined as diagnosis before age 65 years. Participants were followed up from 2009 to 2021. Cox regression models were used to identify predictors of incident dementia.</p><p><strong>Results: </strong>A total of 2 520 839 individuals were included (mean follow-up: 13 years), of whom 79820 (3.25%) had AF at baseline. On univariate analysis, AF was a strong predictor of dementia (HR, 3.39; P<.001). However, after multivariable adjustment, the association was modest (HR, 1.04; P<.001). AF was a stronger independent predictor in individuals aged <70 years (HR, 1.21; P<.001), whereas the association was not significant in those aged ≥70. The strongest association was observed for EOD (HR, 1.36; P<.001). All associations remained consistent in analyses restricted to individuals without prior stroke.</p><p><strong>Conclusions: </strong>In a large Mediterranean cohort, AF was independently associated with a modest increase in dementia risk, regardless of stroke. This association was stronger in younger individuals and in EOD. These findings highlight the need for studies assessing the impact of early identification and management of AF on dementia incidence in younger populations.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic accuracy of quantitative flow ratio for nonculprit intermediate lesions in patients with ST-segment elevation myocardial infarction.","authors":"Emilio Alfonso Rodríguez, Josep Gómez-Lara, Ramón López-Palop, Enrique Gutiérrez, Luis Renier Goncalves Ramírez, José Valencia, Alfonso Jurado-Román, Juan Gabriel Córdoba Soriano, Antonio Gómez-Menchero, Estefanía Fernández-Peregrina, Carlos Cortés, Paula Tejedor, Raúl Millan, Guillermo Sánchez-Elvira, Tamara García-Camarero, José Antonio Linares Vicente, Eva Rúmiz, Rosa María Cardenal Piris, Irene Elizondo Rua, Jean Paul Vilchez, Salvatore Brugaletta, Lara Fuentes, Ana Marcano, Pilar Carrillo, Álvaro Gabaldón, Armando Pérez de Prado, Joan Antoni Gómez-Hospital","doi":"10.1016/j.rec.2025.05.010","DOIUrl":"10.1016/j.rec.2025.05.010","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>The reliability of quantitative flow ratio (QFR) has been questioned. Our aim was to evaluate the diagnostic accuracy of QFR in intermediate nonculprit lesions during the index ST-segment elevation myocardial infarction (STEMI) procedure compared with positive pressure wire-based fractional flow reserve (FFR ≤0.80) in a staged procedure.</p><p><strong>Methods: </strong>This was a substudy of the multicenter, controlled, and randomized VULNERABLE trial, including 428 intermediate nonculprit lesions from 388 consecutive STEMI patients undergoing FFR assessment in a staged procedure between 1 and 60 days. Off-line QFR analyses were performed during both the index and staged procedures. The primary objective was to assess the diagnostic accuracy of index QFR compared with staged positive FFR.</p><p><strong>Results: </strong>Angiographic vessel diameter (2.80±0.59 vs 2.91±0.57mm; P<.01), stenosis severity (51.33±8.04% vs 50.54±7.63%; P=.053), and QFR values (0.85±0.09 vs 0.86±0.09; P=.120) showed minimal changes between the index and staged procedures. Moderate concordance was observed between index QFR and staged FFR (kappa index=0.629; intraclass correlation coefficient=0.641). The diagnostic accuracy of index QFR for predicting positive FFR was good (area under the curve=0.825). An index QFR cutoff ≤0.80 showed moderate sensitivity (72%) and excellent specificity (91%). An index QFR ≤0.87 achieved a sensitivity of 86% for detecting lesions with positive FFR, with 55% of lesions presenting QFR ≤0.87 at the index procedure.</p><p><strong>Conclusions: </strong>Index QFR demonstrated good diagnostic accuracy for identifying lesions with positive FFR in a staged procedure. However, an index QFR cutoff value of ≤0.80 showed moderate sensitivity and may underdiagnose approximately 3 out of 10 lesions with positive FFR. An index QFR ≤0.87 provided higher sensitivity and may help avoid invasive (staged) procedures in many patients.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased cardiovascular mortality in people with disabilities. A challenge that must be addressed.","authors":"Pedro Armario, Montserrat Martín-Baranera","doi":"10.1016/j.rec.2025.05.008","DOIUrl":"10.1016/j.rec.2025.05.008","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144192315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary prevention in older adults: sex differences in statin persistence and cholesterol control.","authors":"Sara Malo, María José Rabanaque, Adriana Gamba, José Manuel Vinuesa-Hernando, Aida Moreno-Juste, María Jesús Lallana, Jesús Cebollada, Isabel Aguilar-Palacio","doi":"10.1016/j.rec.2025.05.007","DOIUrl":"10.1016/j.rec.2025.05.007","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>This study aimed to analyze sex differences in statin persistence and associated factors among individuals aged 70 years and older in Spain who initiated statin therapy for primary prevention of cardiovascular disease. Additionally, it assessed the role of sex in low-density lipoprotein cholesterol (LDL-C) control based on the intensity of statin therapy used.</p><p><strong>Methods: </strong>This was an observational longitudinal study conducted within the CARhES (Cardiovascular risk factors for health services research) cohort. Individuals aged ≥ 70 years who initiated statin therapy for primary prevention of cardiovascular disease between 2018 and 2020 were included. Two-year statin persistence was assessed by sex. Considering major cardiovascular events and death as competing risks, the risk of statin discontinuation and its associated factors were estimated using cumulative incidence functions and Fine and Gray analysis. The proportion of men and women achieving LDL-C target levels was also calculated.</p><p><strong>Results: </strong>A total of 4936 older adults (61.7% women) were included. Compared with men, women had higher mean LDL-C levels prior to statin initiation, a greater pharmacological burden, were less likely to receive high-intensity statins, and demonstrated lower persistence. No variables were statistically associated with discontinuation among women. In men, the adjusted HR for discontinuation was 1.03 (95%CI: 1.00-1.06) per 10mg/dL increase in baseline LDL-C level. Among persistent statin users, women were less likely than men to achieve LDL-C targets, particularly when treated with low- to moderate-intensity statins.</p><p><strong>Conclusions: </strong>Significant sex differences exist in statin persistence, associated factors, and achievement of LDL-C targets among older adults. These findings highlight the importance of considering sex-specific factors when evaluating the appropriateness of statin use in this population.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144192316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From the stethoscope to artificial intelligence: decoding tricuspid disease","authors":"Covadonga Fernández-Golfín ,&nbsp;Ana García-Martín","doi":"10.1016/j.rec.2025.03.011","DOIUrl":"10.1016/j.rec.2025.03.011","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"78 10","pages":"Pages 848-849"},"PeriodicalIF":4.9,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reduced stent strategy versus conventional percutaneous coronary revascularization in patients presenting with STEMI: the COPERNICAN trial.","authors":"Jorge Sanz-Sánchez, Sandra Santos Martínez, Eva Rumiz González, Juan Francisco Oteo Domínguez, David Tejada Ponce, Antonio Gómez Menchero, Guillermo Sánchez Elvira, Georgina Fuertes Ferre, Fernando Rivero Crespo, Antonela Lukic Otanovic, José Díaz Fernández, Eladio Galindo Fernández, Cristóbal Urbano Carrillo, Neus Salvatella Giralt, Mauricio Torres Sánchez, Arturo García Touchard, Borja Ibáñez Cabeza, Giulio Stefanini, Fernando Alfonso Manterola, Héctor García García, Ignacio J Amat-Santos","doi":"10.1016/j.rec.2025.05.005","DOIUrl":"10.1016/j.rec.2025.05.005","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Primary percutaneous coronary intervention (PCI) with drug-eluting stent implantation (DES) is the standard of treatment in patients presenting with ST-segment elevation myocardial infarction (STEMI). However, target lesion failure can occur due to stent underexpansion, malapposition, hypersensitivity, fracture, and neoatherosclerosis. Drug-coated balloons (DCB) represent a potential alternative supported by the concept of \"leaving nothing behind.\" The aim is to compare a reduced stent strategy based on DCB- with DES-PCI in patients presenting with STEMI.</p><p><strong>Methods: </strong>Prospective, pragmatic, multicenter, noninferiority, randomized clinical trial.</p><p><strong>Results: </strong>A total of 1 272 patients presenting with STEMI will be randomized to any paclitaxel-DCB vs any sirolimus-DES (both with CE approval) for all culprit and nonculprit lesions during PCI. The primary endpoint will be target-lesion failure: cardiac death, target-vessel myocardial infarction, or ischemia-driven target lesion revascularization at 12-month follow-up. An independent clinical events committee masked to treatment allocation will adjudicate all suspected events. Clinical follow-up will be performed after 1 month (30 days±5 days) and 1 year (365 days±30 days). An extended follow-up at 3, 5, and 10 years is planned.</p><p><strong>Conclusions: </strong>The COPERNICAN trial will be the first randomized study comparing clinical outcomes of DCB vs DES in STEMI patients.</p><p><strong>Clinicaltrials: </strong>gov: NCT06353594.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravascular ultrasound to assess adverse pulmonary vascular remodeling in Fontan circulation.","authors":"Yassin Belahnech, Gerard Martí-Aguasca, Enric Domingo-Ribas, Eduard Ródenas-Alesina, Antonia Pijuan-Domenech, Laura Dos-Subirà","doi":"10.1016/j.rec.2025.05.004","DOIUrl":"10.1016/j.rec.2025.05.004","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":" ","pages":""},"PeriodicalIF":7.2,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144133153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}