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Integrating soft and hard threshold selection algorithms for accurate segmentation of skin lesion 结合软硬阈值选择算法实现皮肤病灶的精确分割
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-04-07 DOI: 10.1109/MECBME.2014.6783212
A. Masood, Adel Al-Jumaily
{"title":"Integrating soft and hard threshold selection algorithms for accurate segmentation of skin lesion","authors":"A. Masood, Adel Al-Jumaily","doi":"10.1109/MECBME.2014.6783212","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783212","url":null,"abstract":"Accurate segmentation of skin lesion is one of the most important step for automated diagnosis of skin cancer. Various characteristics of skin lesions and intensity variations in images can make it a highly challenging task. A new histogram analysis based fuzzy C mean thresholding method is presented here. It unifies the advantages of soft and hard thresholding algorithms along with reducing the computational complexity. Appropriate threshold value can be calculated even in the presence of abrupt intensity variations. This algorithm shows significantly improved performance for the segmentation of skin lesions. Experimental verification is done on a large set of skin lesion images having almost all types of expected artifacts that may badly affect the segmentation results. Performance evaluation is done by comparing the diagnosis results based on this method with other state of the art thresholding methods. Results show that the proposed approach performs reasonably well and can form a basis of expert diagnostic systems for skin cancer.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"12 7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128280766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Targeted cancer cell death induced by biofunctionalized magnetic nanowires 生物功能化磁性纳米线诱导的靶向癌细胞死亡
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-04-07 DOI: 10.1109/MECBME.2014.6783203
M. Contreras, T. Ravasi, J. Kosel
{"title":"Targeted cancer cell death induced by biofunctionalized magnetic nanowires","authors":"M. Contreras, T. Ravasi, J. Kosel","doi":"10.1109/MECBME.2014.6783203","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783203","url":null,"abstract":"Magnetic micro and nanomaterials are increasingly interesting for biomedical applications since they possess many advantageous properties: they can become biocompatible, they can be functionalized to target specific cells and they can be remotely manipulated by magnetic fields. The goal of this study is to use antibody-functionalized nickel nanowires (Ab-NWs) as an alternative method in cancer therapy overcoming the limitations of current treatments that lack specificity and are highly cytotoxic. Ab-NWs have been incubated with cancer cells and a 12% drop on cell viability was observed for a treatment of only 10 minutes and an alternating magnetic field of low intensity and low frequency. It is believed that the Ab-NWs vibrate transmitting a mechanical force to the targeted cells inducing cell death.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131247234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Toward quantifying geometric microstructural differences between primary and secondary osteons via segmentation 用分割法定量测定原发性骨与继发性骨的几何显微结构差异
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-04-07 DOI: 10.1109/MECBME.2014.6783281
I. Hage, R. Hamade
{"title":"Toward quantifying geometric microstructural differences between primary and secondary osteons via segmentation","authors":"I. Hage, R. Hamade","doi":"10.1109/MECBME.2014.6783281","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783281","url":null,"abstract":"Osteo-histological studies reveal that bones remodel themselves by removing mature bone tissue (bone resorption) from the skeleton and by forming new bone tissue (ossification). In cortical bone, remodeling results in secondary systems replacing of bone that has existed previously (primary bone). In histology slides, secondary bone appears as osteons with central Haversian canals while primary bone appears as interstitial lamellae occupying spaces between osteons. Cement lines refer to the boundaries demarcating the osteons. Although primary and secondary osteons differ micro-structurally, disambiguating such differences in histological studies presents a challenge. This paper aims to quantify such differences using automated segmentation utilizing artificial intelligence and geometric attributes: e.g., area (size), and compactness (shape). Preliminary findings suggest that vascular channels within primary osteons tend to be far more numerous but of smaller sizes than in secondary osteons.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133828111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Early design considerations for a thalamic visual prosthesis to treat blindness resulting from glaucoma 治疗青光眼致盲的丘脑视觉假体的早期设计考虑
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-04-07 DOI: 10.1109/MECBME.2014.6783251
S. M. Tangutooru, W. J. Yoon, J. Troy
{"title":"Early design considerations for a thalamic visual prosthesis to treat blindness resulting from glaucoma","authors":"S. M. Tangutooru, W. J. Yoon, J. Troy","doi":"10.1109/MECBME.2014.6783251","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783251","url":null,"abstract":"Development of visual prostheses for human cortex or retina has gained interest in recent years. However, a visual prosthesis for the thalamic region targeting the lateral geniculate nucleus (LGN) would have many advantages. This paper proposes such a deep brain visual prosthesis that can harness the capacity of the residual central visual neurons following loss of retinal ganglion cells in glaucoma. We believe that such a prosthesis can restore visual percepts, substituting an engineered prosthetic for the image capture and early visual processing properties of the LGN neurons that we propose to drive artificially.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131620516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Enhanced automatic colon segmentation for better cancer diagnosis 增强自动结肠分割，更好的癌症诊断
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-04-07 DOI: 10.1109/MECBME.2014.6783214
M. Ismail, A. Farag, R. Falk, G. Dryden
{"title":"Enhanced automatic colon segmentation for better cancer diagnosis","authors":"M. Ismail, A. Farag, R. Falk, G. Dryden","doi":"10.1109/MECBME.2014.6783214","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783214","url":null,"abstract":"Colon segmentation is the first stage towards polyp detection, the main cause of colon cancer. Due to the immense importance of colon cancer diagnosis which is the second leading cause of death in the world, the segmentation phase must guarantee that no polyps are missed, especially the flat ones that are usually hard to detect. This work validates the 3D automated colon segmentation approach using the convex contour model previously proposed in literature. It also adds improvements to its pre-processing stage in order to better capture the colon walls and to enhance the results of the subsequent phases of the segmentation process. Experiments were conducted on 27 colon data sets that include 30 polyps. Moreover, 30 synthesized polyps with various shapes and sizes were placed at challenging areas of the colon's complex structure. Experiments conducted show a significant improvement in the construction of colon walls and the rate of polyp detection over that provided by the original technique.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126111590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
MUSIC: A hybrid computing environment for burrows-wheeler alignment for massive amount of short read sequence data MUSIC:一个混合计算环境，用于对大量短读序列数据进行钻穴-惠勒对齐
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-02-04 DOI: 10.1109/MECBME.2014.6783237
Saurabh Gupta, Sanjoy Chaudhury, B. Panda
{"title":"MUSIC: A hybrid computing environment for burrows-wheeler alignment for massive amount of short read sequence data","authors":"Saurabh Gupta, Sanjoy Chaudhury, B. Panda","doi":"10.1109/MECBME.2014.6783237","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783237","url":null,"abstract":"High-throughput DNA sequencers are becoming indispensible in our understanding of diseases at molecular level, in marker-assisted selection in agriculture and in microbial genetics research. These sequencing instruments produce enormous amount of data (often terabytes of raw data in a month) that requires efficient analysis, management and interpretation. The commonly used sequencing instrument today produces billions of short reads (upto 150 bases) from each run. The first step in the data analysis step is alignment of these short reads to the reference genome of choice. There are different open source algorithms available for sequence alignment to the reference genome. These tools normally have a high computational overhead, both in terms of number of processors and memory. Here, we propose a hybridcomputing environment called MUSIC (Mapping USIng hybrid Computing) for one of the most popular open source sequence alignment algorithm, BWA, using accelerators that show significant improvement in speed over the serial code.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125362063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A portable 12-lead ECG wireless medical system for continuous cardiac-activity monitoring 用于连续心脏活动监测的便携式12导联心电图无线医疗系统
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-02-01 DOI: 10.1109/MECBME.2014.6783221
J. E. Gaxiola-Sosa, Nasreen Mohsin, A. J. Palliyali, R. Tafreshi, K. Entesari
{"title":"A portable 12-lead ECG wireless medical system for continuous cardiac-activity monitoring","authors":"J. E. Gaxiola-Sosa, Nasreen Mohsin, A. J. Palliyali, R. Tafreshi, K. Entesari","doi":"10.1109/MECBME.2014.6783221","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783221","url":null,"abstract":"This paper presents a 12-lead electrocardiogram (ECG) wireless medical system (WMS) aimed to provide continuous patient monitoring. The WMS consists of three sections: end device (ED), base station (BS) and graphical user interface (GUI). The ED and BS communicate through an RF link that operates in the industrial, scientific and medical (ISM) band at 2.45 GHz. The ED is based on commercially-available ultra-low power integrated circuits, including an 8 channel analog front-end (AFE) intended for biopotential monitoring, a microcontroller unit and an ISM radio transceiver. Details on the 12-lead ECG WMS operation including the low-power oriented control algorithm of the ED and the detection algorithm embedded in the GUI are presented. Measurements of the WMS using a 10 electrode ECG signal generator show successful communication up to 35m line of sight. The ED average current consumption is 33mA (including RF transmission) in continuous operation. This allows the ED to operate up to 88 hours.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123037295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
A phantom for cadaverless evaluation of targeting systems for distal locking of intramedullary nails 用于髓内钉远端锁定靶系统无尸体评估的模型
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-02-01 DOI: 10.1109/MECBME.2014.6783219
Fadi T. Jaber, Awni B. Al-Jayyousi
{"title":"A phantom for cadaverless evaluation of targeting systems for distal locking of intramedullary nails","authors":"Fadi T. Jaber, Awni B. Al-Jayyousi","doi":"10.1109/MECBME.2014.6783219","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783219","url":null,"abstract":"One of the most challenging parts of intramedullary nailing is finding the location of the distal holes of the intramedullary nail following its insertion along the medullary canal. The preferred method for locating the distal holes involves the use of x-ray imaging. In order to reduce the exposure of the medical personnel and patient to ionizing radiation several alternative methods are being investigated and their feasibility and accuracy are being assessed by performing surgery on cadavers. Due to several issues associated with cadavers, this paper introduces a phantom as an alternative tool for the evaluation of such techniques. The features associated with this phantom should allow researchers to assess the performance of their distal locking systems at a reduced cost and without the need for surgical skills.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128072539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Monte Carlo simulation of scatter effect for clinical gamma camera 临床伽玛相机散射效应的蒙特卡罗模拟
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-02-01 DOI: 10.1109/MECBME.2014.6783265
H. Saikouk, N. El Khayati
{"title":"Monte Carlo simulation of scatter effect for clinical gamma camera","authors":"H. Saikouk, N. El Khayati","doi":"10.1109/MECBME.2014.6783265","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783265","url":null,"abstract":"Image in nuclear medicine represents a primordial material in diagnostics and quantitative studies. However, its quality is influenced by factors such as attenuation, scatter and partial volume effects. In the present work we are interested in investigating quantitatively the scatter effect on the spatial resolution and the energy spectrum using the Monte Carlo simulation.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115895575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomedical Engineering Education in the Middle East and North Africa 中东和北非的生物医学工程教育
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-02-01 DOI: 10.1109/MECBME.2014.6783268
Z. O. Abu-Faraj
{"title":"Biomedical Engineering Education in the Middle East and North Africa","authors":"Z. O. Abu-Faraj","doi":"10.1109/MECBME.2014.6783268","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783268","url":null,"abstract":"This paper is an empirical study that aims to characterize the similarities/differences among existing biomedical engineering curricula in the Middle East and North Africa (MENA). The work is based on an earlier study entitled “Project Alexander the Great” that identifies 29 institutions of higher learning within this region, offering degree programs or options in Biomedical Engineering. The objective is to evaluate the curricula of the identified institutions as to their adherence to three major curriculum philosophies: i) VaNTH-ERC (Vanderbilt-Northwestern-Texas-Harvard/MIT Engineering Research Center) Education Mission for Bioengineering and Educational Technologies, ii) Whitaker Curriculum Philosophy, and iii) Accreditation Board for Engineering and Technology Curriculum Philosophy-ABET EC2000. The obtained results reveal that these programs are, to a certain degree, compliant with the requirements of the abovementioned philosophies. As such, the MENA region is witnessing a healthy academic growth and interest in the Biomedical Engineering field. The paper concludes with a referral to a different study by Abu-Faraj that provides a collection of recommendations and strategies to be implemented by entities which are planning to introduce state-of-the-art curricula in this vital field within the MENA region.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124036022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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