2nd Middle East Conference on Biomedical Engineering最新文献

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Influence of stroke location on heart rate variability in robot-assistive neurorehabilitation 脑卒中位置对机器人辅助神经康复中心率变异性的影响
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-04-07 DOI: 10.1109/MECBME.2014.6783252
H. Jelinek, K. August, Md. Hasan Imam, K. Khalaf, A. Koenig, R. Riener, M. Palaniswami, A. Khandoker
{"title":"Influence of stroke location on heart rate variability in robot-assistive neurorehabilitation","authors":"H. Jelinek, K. August, Md. Hasan Imam, K. Khalaf, A. Koenig, R. Riener, M. Palaniswami, A. Khandoker","doi":"10.1109/MECBME.2014.6783252","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783252","url":null,"abstract":"Active mental engagement and a positive emotional state are prerequisites for optimal outcomes of rehabilitation programs for stroke patients. Our program at the ETH, Zurich utilizes a closed loop response in automated robot-assist gait training coupled with virtual reality provided tasks. Heart rate variability has been shown to be sensitive to cognitive as well as emotional states as well as pathophysiological-environmental challenges. We investigated whether adaptation to a task differs between stroke patients with either cortical or subcortical lesions. Seven non-stroke control participants were compared to responses of nine stroke patients with either a diagnosis of cortical or subcortical stroke using heart rate variability. The robot-assist virtual reality training session consisted of a familiarization period, a baseline walking period, an under-challenged, appropriate challenged and over-challenged condition. Time and frequency domain as well as nonlinear features were assessed. Our results indicated that only entropy was sensitive to identifying adaptation to a different level of difficulty. Thus a significant difference was seen between the three stroke groups and control for adaption from baseline to the under-challenged condition (p=0.026), and also from the under-challenged condition to an appropriate level of challenge (p=0.027). We propose that the entropy feature provides a robust index of cognitive and emotional level associated with task difficulty experienced by post-stroke patients that allows real time closed loop regulation of robot-assist gait rehabilitation.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"95 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134445823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
An aortic arch flow loop for the study of hemodynamic-induced endothelial cell injury and inflammation 用于血流动力学诱导的内皮细胞损伤和炎症研究的主动脉弓血流环
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-04-07 DOI: 10.1109/MECBME.2014.6783208
M. M. Alloush, G. F. Oweis, R. Nasr, A. Zeidan
{"title":"An aortic arch flow loop for the study of hemodynamic-induced endothelial cell injury and inflammation","authors":"M. M. Alloush, G. F. Oweis, R. Nasr, A. Zeidan","doi":"10.1109/MECBME.2014.6783208","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783208","url":null,"abstract":"Hemodynamic forces play an important role in maintaining the function and structure of blood vessels. In this work we discuss the design of an in vitro flow loop mimicking the aortic arch that is aimed at studying the response of endothelial cells to geometric curvature and the resulting flow field. The flow system allows for quantitative flow visualization measurements, and for access to the vessel lumen for cell culturing and sampling.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"55 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132115995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A scalable 64 channel neurostimulator based on a hybrid architecture of current steering DAC 基于电流转向DAC混合架构的可扩展64通道神经刺激器
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-04-07 DOI: 10.1109/MECBME.2014.6783218
Mario A. Meza-Cuevas, D. Schroeder, W. Krautschneider
{"title":"A scalable 64 channel neurostimulator based on a hybrid architecture of current steering DAC","authors":"Mario A. Meza-Cuevas, D. Schroeder, W. Krautschneider","doi":"10.1109/MECBME.2014.6783218","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783218","url":null,"abstract":"In this work a 130 nm CMOS 64 channel neural stimulator is presented, which is scalable by connecting it in a daisy chain configuration, for applications requiring larger number of stimulation sites, as it is of interest for retinal implants with improved resolution. Each channel is composed of a hybrid architecture current steering 8 bit DAC, enabling the low power consumption and high channel integration on a small chip area. Besides, the DAC allows stimulating with several waveforms in order to save stimulation energy. An on-chip module was implemented to control galvanostatic deposition of PEDOT on the electrodes. A schema is presented to avoid the residual charge due to cross electrode stimulation and process mismatch.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128998071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Accelerating dynamic MRI by compressed sensing reconstruction from undersampled k-t space with spiral trajectories 从欠采样k-t空间与螺旋轨迹压缩感知重建加速动态MRI
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-04-07 DOI: 10.1109/MECBME.2014.6783197
Azar Tolouee, J. Alirezaie, P. Babyn
{"title":"Accelerating dynamic MRI by compressed sensing reconstruction from undersampled k-t space with spiral trajectories","authors":"Azar Tolouee, J. Alirezaie, P. Babyn","doi":"10.1109/MECBME.2014.6783197","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783197","url":null,"abstract":"Compressed sensing (CS) is a data-reduction technique that has been applied to speed up the acquisition in MRI. In this work, the feasibility of the CS framework for accelerated dynamic MRI is assessed. The fundamental condition of sparsity required in the CS framework is exploited by applying a wavelet transform and a Fourier transform along spatial and temporal directions. The second condition for CS, random sampling, is done by randomly skipping spiral interleaves in each dynamic frame. The proposed approach was tested in simulated and in vivo cardiac MRI data. Results show that higher acceleration factors, with improved spatial and temporal quality, can be obtained with the proposed approach in comparison to the standard CS reconstruction.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129341043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Electrode reduction using ICA and PCA in P300 Visual Speller Brain-Computer Interface system 基于ICA和PCA的P300视觉拼字机脑机接口系统电极还原
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-04-07 DOI: 10.1109/MECBME.2014.6783277
A. E. Selim, M. Wahed, Y. Kadah
{"title":"Electrode reduction using ICA and PCA in P300 Visual Speller Brain-Computer Interface system","authors":"A. E. Selim, M. Wahed, Y. Kadah","doi":"10.1109/MECBME.2014.6783277","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783277","url":null,"abstract":"Brain-Computer Interface (BCI) research aims at developing systems helping disabled people hereafter called subjects. Due to the fact that technology underlying BCI is not yet mature enough and still having shortcomings for usage out of laboratory, these prevent their widespread application. These shortcomings are caused by limitations in functionality of BCI system tools and techniques. The motivation of this work was to develop efficient BCI techniques including signal processing, feature extraction, pattern recognition and classification to improve the performance of P300 Visual Speller BCI system. Data sets used in this paper were acquired using BCI2000's P300 Speller paradigm provided by BCI competitions. Primarily, in the processing phase time domain and spatial domain feature extraction were applied. Followed by classification phase where various linear and extended linear classifiers were utilized. One of the main achievements of this paper is applying Independent Component Analysis (ICA) or Principal Component Analysis (PCA) as spatial domain feature extraction for dimensionality and artifact reduction. Reducing electrodes to half its original size highly improved performance with linear classifiers and yet outperformed the results of BCI competition winners with extended linear classifiers.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131523559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Electrical capacitance volume tomography for human brain motion activity observation 电容量体层析成像在人脑运动活动观察中的应用
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-04-07 DOI: 10.1109/MECBME.2014.6783227
W. Taruno, M. Ihsan, M. Baidillah, Timothy Tandian, Mahdi Mahendra, Mohammed Aljohani
{"title":"Electrical capacitance volume tomography for human brain motion activity observation","authors":"W. Taruno, M. Ihsan, M. Baidillah, Timothy Tandian, Mahdi Mahendra, Mohammed Aljohani","doi":"10.1109/MECBME.2014.6783227","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783227","url":null,"abstract":"In this study we performed brain activity observation related to simple tasks of executed movement (EM) and imagined movement (IM) using Electrical Capacitance Volume Tomography (ECVT). ECVT has been previously applied to brain activity imaging and brain cancer detection. This study is intended to elaborate further the previous studies on the brain functional imaging. Experiment on human subjects was conducted by measuring brain signals using ECVT during five conditions: (1) relax: baseline condition, (2) actual movement with the right hands and left hands, (3) imagined movement with right and left hands. Signal normalization was used to extract the ECVT brain activity signals related to a particular condition. Qualitative and quantitative analysis was performed on the ECVT images of brain activity related to EM and IM tasks. The results indicate that lateral brain activation can be observed using ECVT in concordance with fMRI studies.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131158768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Automatic shadow enhancement in intra vascular ultrasound (IVUS) images 血管内超声(IVUS)图像的自动阴影增强
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-04-07 DOI: 10.1109/MECBME.2014.6783266
Maryam Basij, A. Taki, M. Yazdchi
{"title":"Automatic shadow enhancement in intra vascular ultrasound (IVUS) images","authors":"Maryam Basij, A. Taki, M. Yazdchi","doi":"10.1109/MECBME.2014.6783266","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783266","url":null,"abstract":"The goal of image enhancement is improving the interpretability or perception of information in images for human viewers. This paper describes, an automated algorithm for shadow region detection and enhancement in intravascular ultrasound (IVUS) images using an adaptive threshold method for threshold selection, contour approach for border detection and image enhancement algorithm including histogram analysis for the shadow regions improvement. As shadow appears behind the calcification plaque, it makes it difficult or impossible for the dark region to process automatically around these regions. The acoustic shadow usually follows the hard plaque in IVUS images and it can distinguish calcification regions from other bright regions. Therefore we propose to use Otsu Threshold for calcification plaque segmentation and the Active contours without edge method for shadow region separation of the image and histogram matching for shadow enhancing. Results show that the proposed method efficiently detected shadow regions even in complicated images.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"95 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122161759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
A space-efficient solution to find the maximum overlap using a compressed suffix array 使用压缩后缀数组查找最大重叠的节省空间的解决方案
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-04-07 DOI: 10.1109/MECBME.2014.6783270
M. Rachid, Q. Malluhi, M. Abouelhoda
{"title":"A space-efficient solution to find the maximum overlap using a compressed suffix array","authors":"M. Rachid, Q. Malluhi, M. Abouelhoda","doi":"10.1109/MECBME.2014.6783270","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783270","url":null,"abstract":"Compressed indices are important data structures in stringology. Compressed versions of many well-known data structures such as suffix tree and suffix array, which are used in string matching problems, have been studied and proposed. This paper takes advantage of a very recent compressed suffix array to build a space-economic solution for an important bioinformatics problem, namely the all-pairs suffix prefix problem. The paper also presents a simple technique for parallelizing the solution. Our results show that the proposed solution consumes less than one fifth of the space required by other solutions based on standard data structures. In addition, our results demonstrate that good performance scalability can be achieved by employing the proposed parallel algorithm.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"310 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120932443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
A two layer texture modeling based on curvelet transform and spiculated lesion filters for recognizing architectural distortion in mammograms 基于曲波变换和针状病变滤波器的两层纹理建模用于乳房x线照片的结构畸变识别
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-04-07 DOI: 10.1109/MECBME.2014.6783198
Sahar Khoubani, Hamid Sheikhzadeh Nadjar, E. Fatemizadeh, Elham Mohammadi
{"title":"A two layer texture modeling based on curvelet transform and spiculated lesion filters for recognizing architectural distortion in mammograms","authors":"Sahar Khoubani, Hamid Sheikhzadeh Nadjar, E. Fatemizadeh, Elham Mohammadi","doi":"10.1109/MECBME.2014.6783198","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783198","url":null,"abstract":"This paper presents a two layer texture modeling method to recognize architectural distortion in mammograms. We propose a method that models a Gaussian mixture on the Curvelet coefficients and the outputs of Spiculated Lesion Filters. The Curvelet transform and the Spiculated Lesion Filters have been applied to extract textural features of mammograms in literature. However the key difference between this study and the previous ones is that in our approach, a Gaussian mixture models the textural features extracted by the Curvelet transform and the Spiculated Lesion Filters. The results of the current study are shown in the form of accuracy and the area under the receiver operating characteristic curves on the DDSM and MIAS databases. The results suggest that the proposed method outperforms the previous work about 17.90% in accuracy and 0.19 in area under the receiver operating characteristic. The maximum achieved accuracy of our method is 92.78 %.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"142 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121074938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Modulation of mRNA circadian transcription cycle by microRNAs microRNAs对mRNA昼夜转录周期的调控
2nd Middle East Conference on Biomedical Engineering Pub Date : 2014-04-07 DOI: 10.1109/MECBME.2014.6783235
A. Ptitsyn, N. Ptitsyna, Emad Elsebakhi, F. Marincola, Rashid J. Al-Ali, M. Temanni, Rawan AlSaad, E. Wang
{"title":"Modulation of mRNA circadian transcription cycle by microRNAs","authors":"A. Ptitsyn, N. Ptitsyna, Emad Elsebakhi, F. Marincola, Rashid J. Al-Ali, M. Temanni, Rawan AlSaad, E. Wang","doi":"10.1109/MECBME.2014.6783235","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783235","url":null,"abstract":"MicroRNAs are important modulators of gene expression. There is anecdotal evidence that the abundance of some microRNAs varies in circadian or approximately daily rhythm. In this study, using publicly available data we attempt a systematic analysis of co-expression between microRNAs and their prospective mRNA targets. An advanced analysis of periodicity with the application of digital filters in phase continuum revealed a baseline rhythmic oscillation on over 80% of both mRNA and microRNA populations. This computational observation adds evidence to the theory that microRNAs play an active role in modulation of rhythmic expression as a general rule rather than special exemption. We also explore the immediate implications of inferred oscillatory behavior for modeling of mRNA-miRNA dynamics.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115753040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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