{"title":"Toward an integrated e-health based on acquired healthcare knowledge","authors":"S. Nasiri, M. Fathi","doi":"10.1109/MECBME.2014.6783264","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783264","url":null,"abstract":"In order to have an integrated knowledge based e-health, several tools are used. Some of them make knowledge accessible to users and support users in the exchange of knowledge (e.g. knowledge portals, applications). In this way through integrating knowledge, extraction of the knowledge from different sources and analyzes it in a knowledge-based way along with interaction of stakeholders and domain experts, leads to have a better care documentation and also a better communication between them.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117177986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rasha S. Aboul-Yazeed, Abdallah S. A. Mohamed, A. El-Bialy
{"title":"Edge-based IVD segmentation system","authors":"Rasha S. Aboul-Yazeed, Abdallah S. A. Mohamed, A. El-Bialy","doi":"10.1109/MECBME.2014.6783213","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783213","url":null,"abstract":"Computer-aided diagnosing (CAD) and computer-assisted surgery (CAS) systems for spine and intervertebral disc (IVD) necessitate highly speed, minimal memory usage and accurate segmentation system because such system has a direct impact on spinal disease diagnosis and surgical planning. An unsupervised edge-based IVD segmentation system is proposed and validated on eight different lower back pain patients with MR sagittal and axial plane images. It achieves 0.98275, 0.9924 mean dice similarity coefficient (DSC) and 0.9733, 0.9735 mean area under the receiver operating characteristic (ROC) curve for sagittal and axial planes respectively. It requires averages of 26.017s and 431MB of memory usage for axial plane.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121706601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Towards real-time remote diagnostics of capsule endoscopic images using Wi-Fi","authors":"Ravi Shrestha, T. Khan, K. Wahid","doi":"10.1109/MECBME.2014.6783262","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783262","url":null,"abstract":"The paper presents a design of a microcontroller based Wi-Fi adapter that can be used in wireless capsule endoscopy application. Using the proposed adapter, image data from an endoscopic capsule, after swallowing, can be can be saved (or logged) directly on smart device, laptop, workstation or server that are connected to hospital's Wi-Fi network. This enables medical doctors to analyze data in real time during examination from a remote place. Two case studies are shown where (a) an Android mobile app for Smartphone and (b) computer software for standalone laptop workstation have been developed. The design has been prototyped in laboratory and the advantage of the proposed adapter is demonstrated for capsule endoscopy application. The proposed W-Fi adapter is also useful for other external or implantable biosensors with similar advantages where remote viewing and diagnosis in real-time are desired.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125503643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of a fuzzy learning intervention approach to a purine metabolism pathway model","authors":"N. Basha, H. Nounou, M. Nounou","doi":"10.1109/MECBME.2014.6783233","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783233","url":null,"abstract":"Adaptive fuzzy control is used here to enforce a concentration level of some metabolite of a biological system representing a purine metabolism pathway model to track a reference trajectory in the presence of uncertainties. In contrast to the direct fuzzy controller, the adaptive fuzzy controller is able to reduce the variance of both the system's response and the controller's output. In this paper, we will apply the adaptive fuzzy intervention strategy to the purine metabolism pathway model in the presence of output noise, which is the source of the model's uncertainties, and carry out a sensitivity analysis of the controller's behavior. The simulation will also be carried out using the direct fuzzy controllers, as described in [1], and the results will be compared and analyzed.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131475440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Numerical characterisation and modeling of in-vivo radio communication","authors":"Q. Abbasi, M. Qaraqe, E. Serpedin","doi":"10.1109/MECBME.2014.6783279","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783279","url":null,"abstract":"In this paper, preliminary study on path loss characterization of in-vivo communication channel at 2.45 GHz using numerical modeling is presented. One of the antennas is implanted inside the chest and the second antenna is placed on the surface of body at certain distance. The on-body antenna is rotated at different angles with respect to the inbody antenna and path loss is calculated at certain fixed distance. The body-centric path loss is compared with the free space path loss as well. Results show that there is almost 10-15 dB variation in path loss in case of in-vivo channel as compared to free space. Also a degradation in path loss and channel response with respect to the orientation angle between implanted transmitter and on-body receiver is observed, which highlights the importance of carefully considering the location of on-body receiver for optimal system performance.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121312466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdelmoamen K. Aljehani, M. A. Hussaini, M. Hussain, Nazeeh Alothmany, R. Aldhaheri
{"title":"Effect of electrospinning parameters on nanofiber diameter made of poly (vinyl alcohol) as determined by Atomic Force Microscopy","authors":"Abdelmoamen K. Aljehani, M. A. Hussaini, M. Hussain, Nazeeh Alothmany, R. Aldhaheri","doi":"10.1109/MECBME.2014.6783283","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783283","url":null,"abstract":"A solution of poly (vinyl alcohol) (PVA) in water was electrospun into ultrafine nanofibers using a commercially available electrospinning set-up. Some major electrospinning parameters such as the concentration of polymer solution, flow rate, spinning voltage and distance between the needle tip and collection target were chosen to investigate its effect on the topological morphology as well as the average diameter of the electronspun PVA nanofibers using Atomic Force Microscopy (AFM). Diameters of the nanofibers obtained ranged from 150 nm to 900 nm. The diameters of electrospun nanofibers were most significantly affected by the concentration of polymer solution. While lower concentration always gave rise to the formation of discontinuous nanofibers with beads, an increasing concentration yielded smooth and uniform nanofibers with increasing diameters and beaded morphology was found disappearing. Keeping solution concentration constant at a higher value that yielded smooth nanofibers, an increase in the flow rate again changed the morphology from smooth to beaded morphology of nanofibers obtained. Spinning voltage did not show any specific trend of diameter change at a wider range (10 to 25 kV) selected in this study.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127851962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Sefat, Ílida Ortega, Robert Mckean, P. Deshpande, Charanya Ramachandran, C. J. Hill, S. Tzokov, F. Claeyssens, V. Sangwan, A. Ryan, S. MacNeil
{"title":"An “off-the shelf” synthetic membrane to simplify regeneration of damaged corneas","authors":"F. Sefat, Ílida Ortega, Robert Mckean, P. Deshpande, Charanya Ramachandran, C. J. Hill, S. Tzokov, F. Claeyssens, V. Sangwan, A. Ryan, S. MacNeil","doi":"10.1109/MECBME.2014.6783206","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783206","url":null,"abstract":"Our overall aim is to develop a synthetic off-the-shelf alternative to human amniotic membrane which is currently used for delivering cultured limbal stem cells to the cornea in patients who suffer scarring of the cornea because of the loss of limbal stem cells. We have recently reported that both cultured cells and limbal explants grow well on electrospun Poly(D, L-lactide-co-glycolide) (PLGA) (44 kg/mol) with a 50:50 ratio of lactide and glycolide and sterilized with γ-irradiation. Prior to undertaking a clinical study our immediate aim now is to achieve long term storage of the membranes in convenient to use packaging. Membranes were electrospun from Poly(D, L-lactide-co-glycolide) (44 kg/mol) with a 50:50 ratio of lactide and glycolide and sterilized with γ-irradiation and then stored dry (with desiccant) for several months at -80°C and -20°C, Room temperature (UK and India), 37°C and 50°C. We explored the contribution of vacuum sealing and the use of a medical grade bag (PET/Foil/LDPE) to achieve a longer shelf life. Confirmation of membranes being suitable for clinical use was obtained by culturing tissue explants on membranes post storage. When scaffolds were stored dry the rate of breakdown was both temperature and time dependent. At -20°C and -80°C there was no change in fiber diameter over 18 months of storage, and membranes were stable for 12 months at 4°C while at 50°C (above the transition temperature for PLGA) scaffolds lost integrity after several weeks. The use of vacuum packaging and a medical grade bag both improved the storage shelf-life of the scaffolds. The impact of temperature on storage is summarized beneath. We report that this synthetic membrane can be used as an off-the-shelf or-out-of-the freezer alternative to the amniotic membrane for corneal regeneration.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132658258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Parisa Pooyan, L. Brewster, R. Tannenbaum, H. Garmestani
{"title":"Biomimetic engineering of a fully bio-based system in nanomedicine","authors":"Parisa Pooyan, L. Brewster, R. Tannenbaum, H. Garmestani","doi":"10.1109/MECBME.2014.6783282","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783282","url":null,"abstract":"Design of materials and devices by mimicking the fascinating systems found in nature, have enabled scientists to discover new techniques to treat diseases from diagnosis to therapeutic care. With the recent advances in nanomedicine, the length-scale of this design has further extended down into a nano-sized array. Inspired by the two natural assemblies found in nature; cellulose and collagen; we have designed a new class of green functional material with nano-sized arrangement. The fabricated material composed of collagen hydrogel reinforced by cellulose nanowhiskers in order to effectively enhance the rigidity of collagen and to better mimic the morphology and profile features existed in biological tissues. The biocompatibility of the hydrogel nanocomposite was also investigated by the invasion and proliferation of human bone marrow derived mesenchymal stem cells around the materials at 8 day of culture. We believe that our biomimetically-engineered platform in this study could increase the biomedical applications of fully bio-based systems such as scaffolding in tissue engineering.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131212172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Non-invasive extraction of fetal electrocardiogram using fast independent component analysis technique","authors":"D. Shehada, A. Khandoker","doi":"10.1109/MECBME.2014.6783275","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783275","url":null,"abstract":"Fetal electrocardiogram (fECG) provides clinically important information concerning the electrophysiological state of a fetus. The fECG contains activity of electrical depolarization and repolarization of fetal heart. In this paper a technique is proposed called Fast Independent Component Analysis (Fast ICA) to extract the fECG signals from the 20 sets of abdominal ECG signals. Using Fast ICA, 91.4% R peaks of fECG signals were extracted as validated by the direct fECG R peaks measured from scalp. The mother electrocardiogram (mECG) is extracted from the four channel abdominal ECGs, canceled and then the fECG is extracted. Bland Altman and correlation calculations showed no significant difference between the extracted fECG and direct fECG RR intervals. The correlation coefficient ρ was 0.84 and the p value was 0.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128442514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Swarm-based extreme learning machine for finger movement recognition","authors":"K. Anam, Adel Al-Jumaily","doi":"10.1109/MECBME.2014.6783257","DOIUrl":"https://doi.org/10.1109/MECBME.2014.6783257","url":null,"abstract":"An accurate finger movement recognition is required in many robotics prosthetics and assistive hand devices. The use of a small number of Electromyography (EMG) channels for classifying the finger movement is a challenging task. This paper proposes a novel recognition system which employs Spectral Regression Discriminant Analysis (SRDA) for dimensionality reduction, kernel-based Extreme Learning Machine (ELM) for classification and the majority vote for classification smoothness. Particle Swarm Optimization (PSO) is used to optimize the kernel-based ELM. Three hybridizations with three kernels, radial basis function (SRBF-ELM), linear (SLIN-ELM), and polynomial (SPOLY-ELM) are introduced. The experimental results show that SRBF-ELM significantly outperforms SLIN-ELM but not too much different compared to SPOLY-LIN. Moreover, PSO is able to optimize the three systems by giving the accuracy more than 90% with the highest accuracy is ~94%.","PeriodicalId":384055,"journal":{"name":"2nd Middle East Conference on Biomedical Engineering","volume":"246 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134027716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}