Wound Medicine最新文献_第9页

Socio-demography and clinical profile of venous ulcers 静脉溃疡的社会人口学和临床特征

Wound Medicine Pub Date : 2017-12-01 DOI: 10.1016/j.wndm.2017.06.004

Dheepak Selvaraj, Albert Kota, Prabhu Premkumar, Edwin Stephen, Sunil Agarwal

{"title":"Socio-demography and clinical profile of venous ulcers","authors":"Dheepak Selvaraj, Albert Kota, Prabhu Premkumar, Edwin Stephen, Sunil Agarwal","doi":"10.1016/j.wndm.2017.06.004","DOIUrl":"10.1016/j.wndm.2017.06.004","url":null,"abstract":"<div><h3>Introduction</h3><p>Venous ulcers<span><span> are the most common type of non-healing ulcers. They constitute 70% of the chronic leg ulcers. They have significant socioeconomic and psychological consequences reducing the </span>quality of life. There are few Indian studies documenting the extent of the disease</span></p></div><div><h3>Methods</h3><p>All patients with chronic venous ulcers of duration more than 6 months were included from January 2014 to July 2015. Their socio-demographic data such as age, sex, education, occupation, income, socioeconomic status and residential geographic location were documented. Clinical information included size of the ulcer, duplex findings were also noted.</p></div><div><h3>Results</h3><p>There were 217 patients. There was male preponderance m: f (8.4:1). Most of them belonged to the economically productive age group of 36 to 45 years and belonged to the middle socioeconomic group. Perforator incompetence was noted to be common in all patients.</p></div><div><h3>Conclusions</h3><p>Venous ulcers are common in India. They affect middle age group men predominantly and also belonging to the middle socio-economic group.</p></div>","PeriodicalId":38278,"journal":{"name":"Wound Medicine","volume":"19 ","pages":"Pages 1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.wndm.2017.06.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42359680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Treatment of skin and soft tissue infections caused by Pseudomonas aeruginosa—A review of our experiences with citric acid over the past 20 years 柠檬酸治疗铜绿假单胞菌引起的皮肤和软组织感染的研究综述

Wound Medicine Pub Date : 2017-12-01 DOI: 10.1016/j.wndm.2017.09.005

Basavraj Nagoba , Milind Davane , Rajan Gandhi , Bharat Wadher , Namdev Suryawanshi , Sohan Selkar

引用次数: 16

Factors affecting the outcome and duration of healing of the laid open wound for sacrococcygeal pilonidal sinus: A prospective cohort study of 472 patients 影响骶尾椎毛突窦开放性伤口疗效和愈合时间的因素:一项472例患者的前瞻性队列研究

Wound Medicine Pub Date : 2017-09-01 DOI: 10.1016/j.wndm.2017.06.005

Bader Hamza Shirah , Hamza Asaad Shirah

{"title":"Factors affecting the outcome and duration of healing of the laid open wound for sacrococcygeal pilonidal sinus: A prospective cohort study of 472 patients","authors":"Bader Hamza Shirah , Hamza Asaad Shirah","doi":"10.1016/j.wndm.2017.06.005","DOIUrl":"10.1016/j.wndm.2017.06.005","url":null,"abstract":"<div><h3>Objectives</h3><p><span>Recent clinical reports showed excellent results when the lay open method was used for the treatment of chronic </span>sacrococcygeal pilonidal sinus, despite keeping the wound open for a considerable time which increases the risk of infection, delayed closure, and recurrence. In this study, we aim to analyze the factors influencing the outcome of the laid open sacrococcygeal pilonidal wound regarding wound infection, complete wound closure, and recurrence.</p></div><div><h3>Methods</h3><p>A prospective cohort study of 472 patients with chronic sacrococcygeal pilonidal sinus who had the lay open procedure between January 2000 and December 2012 was done. 326 were male and 146 were female. Lay open was performed to all patients. Postoperative care and follow-up methods were similar in all patients. Preoperative, intraoperative, and postoperative factors affecting the outcome were analyzed.</p></div><div><h3>Results</h3><p>The mean age was 27.6 years. Male gender, smoking, BMI≥30kg/m<sup>2</sup>, diabetes mellitus, the sinus number, wound depth of more than 3≤0.01). The recurrence rate was 0% after four years of follow-up.</p></div><div><h3>Conclusion</h3><p>We concluded that many factors could affect the outcome of the laid open wound of the chronic sacrococcygeal pilonidal sinus. For the best outcome, careful consideration of these factors could help achieve an excellent result.</p></div>","PeriodicalId":38278,"journal":{"name":"Wound Medicine","volume":"18 ","pages":"Pages 52-56"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.wndm.2017.06.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45755893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Natural and bio polymer curative films for wound dressing medical applications 医用伤口敷料用天然和生物聚合物治疗膜

Wound Medicine Pub Date : 2017-09-01 DOI: 10.1016/j.wndm.2017.07.002

P. Ganesan

引用次数: 30

HDNC (1-hydroxy-5, 7-dimethoxy-2 naphthalene-carboxaldehyde) for rapid recovery of gastric damage in incision wound model of rats HDNC（1-羟基-5,7-二甲氧基-2萘甲醛）对大鼠切口创伤模型胃损伤的快速恢复作用

Wound Medicine Pub Date : 2017-09-01 DOI: 10.1016/j.wndm.2017.06.002

Lubna Azmi , Ila Shukla , Shyam Sundar Gupta , Shravan Kumar Paswan , Padam Kant , Ch.V. Rao

{"title":"HDNC (1-hydroxy-5, 7-dimethoxy-2 naphthalene-carboxaldehyde) for rapid recovery of gastric damage in incision wound model of rats","authors":"Lubna Azmi , Ila Shukla , Shyam Sundar Gupta , Shravan Kumar Paswan , Padam Kant , Ch.V. Rao","doi":"10.1016/j.wndm.2017.06.002","DOIUrl":"10.1016/j.wndm.2017.06.002","url":null,"abstract":"<div><p>HDNC (1-hydroxy-5, 7-dimethoxy-2 naphthalene-carboxaldehyde) is a bioactive compound derived from <em>Aegle marmelos</em> (Rutaceae, ‘Bael’). The current study was conducted to conclude the effect of HDNC on mechanical properties and collagen content of stomach and duodenal wounds in rats. This experiment included wound creation in rumen (non-glandular part) & corpus (oxyntic) part of stomach and duodenum. These wounds were analyzed after 0, 5, 15 & 30days post-operation. HDNC treatment found to improve the mechanical strength of healing wounds of stomach and duodenum. Breaking strength and breaking energy were also augmented in presence of HDNC. Healing process was slower in initial post-operative phase (after 5days). However in later days wound strength enhanced drastically. Direct relation was observed between total collagen content and mechanical strength. These findings point towards that the amplification of mechanical strength and collagen content in wounds has been the outcome of HDNC treatment.</p></div>","PeriodicalId":38278,"journal":{"name":"Wound Medicine","volume":"18 ","pages":"Pages 47-51"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.wndm.2017.06.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42466080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Honey and epithelial to mesenchymal transition in wound healing: An evidence-based review 蜂蜜和伤口愈合中上皮细胞到间质细胞的转变:一项基于证据的综述

Wound Medicine Pub Date : 2017-09-01 DOI: 10.1016/j.wndm.2017.06.003

Abid Nordin , Nur Qisya Afifah Veronica Sainik , Mohamed S. Zulfarina , Isa Naina-Mohamed , Aminuddin Saim , Ruszymah Bt Hj Idrus

{"title":"Honey and epithelial to mesenchymal transition in wound healing: An evidence-based review","authors":"Abid Nordin , Nur Qisya Afifah Veronica Sainik , Mohamed S. Zulfarina , Isa Naina-Mohamed , Aminuddin Saim , Ruszymah Bt Hj Idrus","doi":"10.1016/j.wndm.2017.06.003","DOIUrl":"10.1016/j.wndm.2017.06.003","url":null,"abstract":"<div><p>This review inspects all the available report on association of honey and the epithelial mesenchymal transition (EMT) event in wound healing. A systematic review of the literature was conducted to identify relevant studies on honey and EMT. The search was done in Medline via Ebscohost and Scopus database to obtained relevant articles published between 1823 and 2017. The main inclusion criteria were research articles published in English that reported changes in the EMT markers in <em>in vitro</em> wound healing model when subjected to honey. The literature search identified 19 potentially relevant articles, whereby 8 met the inclusion criteria. Two types of <em>in vitro</em> wound healing model were included, cutaneous and corneal wound. All studies reported a positive effect of honey in wound healing. In terms of EMT markers, honey was shown to upregulate mesenchymal markers and downregulated epithelial markers providing the evidence of EMT activation by honey. However, the effects on EMT varied dependent on the floral origin of the honey. This review provides good evidence that honey regulates the process of EMT and has a positive impact on wound healing.</p></div>","PeriodicalId":38278,"journal":{"name":"Wound Medicine","volume":"18 ","pages":"Pages 8-20"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.wndm.2017.06.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55277956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Classification of diabetic foot, revisited 糖尿病足的分类，重新审视

Wound Medicine Pub Date : 2017-09-01 DOI: 10.1016/j.wndm.2017.06.001

V.N. Obolenskiy , V.G. Protsko , E.Y. Komelyagina

引用次数: 5

Effect of Lawsonia inermis (Henna) on wound healing in Sprague-Dawley rats: A pilot study 指甲花对Sprague-Dawley大鼠伤口愈合影响的初步研究

Wound Medicine Pub Date : 2017-09-01 DOI: 10.1016/j.wndm.2017.07.004

Abdulwahid M. Salih , Fahmi H. Kakamad , Rawezh Q. Salih , Dahat A. Hussein , Hunar A. Hassan , Tomas M. Mekail , Jeza M. Abdul Aziz , Han Aube

{"title":"Effect of Lawsonia inermis (Henna) on wound healing in Sprague-Dawley rats: A pilot study","authors":"Abdulwahid M. Salih , Fahmi H. Kakamad , Rawezh Q. Salih , Dahat A. Hussein , Hunar A. Hassan , Tomas M. Mekail , Jeza M. Abdul Aziz , Han Aube","doi":"10.1016/j.wndm.2017.07.004","DOIUrl":"10.1016/j.wndm.2017.07.004","url":null,"abstract":"<div><p><span>Leaves of Lawsonia inermis have long been used for several purposes in traditional herbal medicine<span><span><span>. This report is to evaluate the effect of Lawsonia inermis on the wound healing in rats. Eight adult male rats were used. Animals have been anesthetized. A wound was created on the dorsal nape of the neck. Group 1 were left without </span>treatment. Group 2 treated with 10% Iodine and vehicle. Group 3 and 4 were treated with a low dose and high dose of Henna respectively for 15 days. On the 1 ,5,10 and 15, the wound area of each animal was measured. </span>Wound contraction was calculated. On the day 15, tissue samples were taken from the wound and examined by a histopathologist. At day 15, the average wound size decreased in group 1 and group 2 to 5.5</span></span>   <!-->mm respectively. Histological results revealed that low dose and high dose produce better wound healing if compared with the control positive and control negative. The result of this pilot study has revealed that Henna extract leaves have remarkable effects on wound healing and warrents further studies.</p></div>","PeriodicalId":38278,"journal":{"name":"Wound Medicine","volume":"18 ","pages":"Pages 41-42"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.wndm.2017.07.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41929780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Mango cut incision for pressure ulcer necrotic tissue clearance: An easier and safer method to facilitate chemical debridement in severely-comorbid patients 芒果切口用于压疮坏死组织清除:对严重合并症患者进行化学清创的一种更简单、更安全的方法

Wound Medicine Pub Date : 2017-09-01 DOI: 10.1016/j.wndm.2017.07.003

Takumi Yamamoto , Nana Yamamoto

{"title":"Mango cut incision for pressure ulcer necrotic tissue clearance: An easier and safer method to facilitate chemical debridement in severely-comorbid patients","authors":"Takumi Yamamoto , Nana Yamamoto","doi":"10.1016/j.wndm.2017.07.003","DOIUrl":"10.1016/j.wndm.2017.07.003","url":null,"abstract":"<div><h3>Background</h3><p><span>Treatment<span> of pressure ulcer with necrotic tissue formation is challenging in old patients with severe comorbidities. Although indicated and recommended, surgical </span></span>debridement cannot always be applied because of general conditions. Simple, convenient, and minimally invasive intervention is required to facilitate chemical debridement of necrotic tissue.</p></div><div><h3>Methods</h3><p>Seventeen patients suffering from intractable pressure ulcer complicated with necrotic tissue formation underwent conventional debridement (CD) or mango cut incision (MCI). Feasibility of MCI method was evaluated by comparing clinical outcomes between patients who underwent CD and MCI.</p></div><div><h3>Results</h3><p>Between patients undergoing CD and MCI, there was no significant difference in time for necrotic tissue clearance (3.1±2.0 vs. 4.0±1.5 weeks, <em>P</em>      =0.566). Time required for intervention was significantly longer in CD than that in MCI (173.8±44.5 vs. 29.4±13.3s, <em>P</em>  =0.043).</p></div><div><h3>Conclusions</h3><p>MCI allows minimally invasive clearance of necrotic tissue with clinically acceptable outcomes compatible to CD, and can be a choice of method for necrosis-complicated pressure ulcers in patients with severe comorbidities.</p></div>","PeriodicalId":38278,"journal":{"name":"Wound Medicine","volume":"18 ","pages":"Pages 43-46"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.wndm.2017.07.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47828812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Therapeutic interfaces of honey in diabetic wound pathology 蜂蜜在糖尿病伤口病理中的治疗界面

Wound Medicine Pub Date : 2017-09-01 DOI: 10.1016/j.wndm.2017.07.001

Satarupa Sarkar , Anurup Mukhopadhyay , Amrita Chaudhary , Monika Rajput , Harpreet Singh Pawar , Rabibrata Mukherjee , Amit Kumar Das , Provas Banerjee , Jyotirmoy Chatterjee

引用次数: 7