Treatment of skin and soft tissue infections caused by Pseudomonas aeruginosa—A review of our experiences with citric acid over the past 20 years

Q1 Medicine

Wound Medicine Pub Date : 2017-12-01 DOI:10.1016/j.wndm.2017.09.005

Basavraj Nagoba , Milind Davane , Rajan Gandhi , Bharat Wadher , Namdev Suryawanshi , Sohan Selkar

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引用次数: 16

Abstract

Multiple antibiotic resistant Pseudomonas aeruginosa is a significant cause of burn wound infections and, skin and soft tissue infections. Because of its resistance to commonly used antibiotics and antiseptics, there is a shortage of therapeutic options for effective treatment. The present review summarizes the use of citric acid as a most potential substitute for antiseptics to control pseudomonal wound infections and its role in the process of wound healing. The various studies show that citric acid can be used as one of the alternatives when infection is caused by multiple antibiotic resistant strains of P. aeruginosa not responding to conventional treatment modality. The results of various earlier studies show that when resistance to antibiotics and antiseptics is a matter of great concern, citric acid as one of the potential alternatives should always be kept in mind.

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柠檬酸治疗铜绿假单胞菌引起的皮肤和软组织感染的研究综述

多重耐药铜绿假单胞菌是烧伤创面感染、皮肤和软组织感染的重要原因。由于它对常用的抗生素和防腐剂具有耐药性，因此缺乏有效治疗的治疗选择。本文综述了柠檬酸作为一种最有潜力的防腐剂在控制假单胞菌伤口感染中的应用及其在伤口愈合过程中的作用。各种研究表明，当铜绿假单胞菌多重耐药菌株引起感染而常规治疗方式无效时，柠檬酸可作为替代方案之一。各种早期研究的结果表明，当对抗生素和防腐剂的耐药性是一个非常关注的问题时，柠檬酸作为潜在的替代品之一应该始终牢记在心。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Wound Medicine Medicine-Surgery

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