Natural and bio polymer curative films for wound dressing medical applications

Abstract

This work was initiated to develop a new form of curative film wound dressing, by the combination of silk fibroin, wool keratin, chitosan and honey act as a drug releasing agent on the wound surface for biodegradable wound dressings with desirable wound healing properties. The film formation was carried out using casting technique. The surface morphology of the films was carried out using Scanning Electron Microscope. The physical properties of film were assed as per standard methods The bio evaluation characteristics like antimicrobial efficacy were measured both in terms of zone of inhibition of the film samples against on Staphylococcus aureus and Escherichia coli. In another hand microbial penetration test, drug release activity, cytotoxicity test, contact dermatitis test were analyzed as per the standards.