Biotribology最新文献_第8页

Tribocorrosion of Polyethylene/Cobalt Contact Combined with Real-Time Fluorescence Assays on Living Macrophages: Development of A Multidisciplinary Biotribocorrosion Device 聚乙烯/钴接触的摩擦腐蚀结合实时荧光检测活巨噬细胞：一种多学科生物核糖腐蚀装置的研制

Biotribology Pub Date : 2019-06-01 DOI: 10.1016/j.biotri.2019.100091

A. Impergre , A.M. Trunfio-Sfarghiu , C. Der-Loughian , L. Brizuela , S. Mebarek , B. Ter-Ovanessian , A. Bel-Brunon , Y. Berthier , B. Normand

{"title":"Tribocorrosion of Polyethylene/Cobalt Contact Combined with Real-Time Fluorescence Assays on Living Macrophages: Development of A Multidisciplinary Biotribocorrosion Device","authors":"A. Impergre , A.M. Trunfio-Sfarghiu , C. Der-Loughian , L. Brizuela , S. Mebarek , B. Ter-Ovanessian , A. Bel-Brunon , Y. Berthier , B. Normand","doi":"10.1016/j.biotri.2019.100091","DOIUrl":"10.1016/j.biotri.2019.100091","url":null,"abstract":"<div>The test conditions currently used in biotribocorrosion devices often differ greatly from the physiological conditions of joint replacements, contributing to discrepancies between the simulated and actual life span of joint replacements. In this study, a multidisciplinary biotribocorrosion device was developed based on the limitations of existing tribocorrosimeters. The set-up enables corrosion measurements to be simultaneously performed with real-time visualization of living cells using fluorescence microscopy under dynamic loads and movements. The device was configured to simulate the joint contact of ankle prostheses, and the wear of ultra-high-molecular-weight polyethylene/cobalt alloy (CoCrMo) implants surrounded by murine macrophages was tested. Various characterization techniques (non-contact optical profilometry, scanning and fluorescence electron microscopy and quantitative analyses of metal ions and pro-inflammatory cytokines) were combined in-depth multidisciplinary study. Two experimental conditions were used to promote the production of either polyethylene wear particles or metal ions. The first results indicated two distinct tribocorrosion mechanisms: 1) adhesive wear coupled with slow ionic depassivation of the cobalt alloy. The main degradation products were micrometric spherical polyethylene particles that seem to have little impact effect on the metabolic activity of the macrophages. 2) Ionic wear with the production of small, fibrillar polyethylene particles was observed. The production of metal ions, mainly chromium, was the predominant degradation process. The cytotoxicity of the chromium ions was evaluated based on the secretion of pro-inflammatory cytokines (prostaglandin E2). Our findings indicate that simulated conditions that result in low mechanical wear but high ions release appear to be more harmful to cells.</div>","PeriodicalId":38233,"journal":{"name":"Biotribology","volume":"18 ","pages":"Article 100091"},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.biotri.2019.100091","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42910461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

An Empirical Approach for the Determination of Skin Elasticity: Finger pad Friction against Textured Surfaces 确定皮肤弹性的经验方法：指垫与纹理表面的摩擦

Biotribology Pub Date : 2019-06-01 DOI: 10.1016/j.biotri.2019.100097

D.A. Sergachev , D.T.A. Matthews , E. van der Heide

{"title":"An Empirical Approach for the Determination of Skin Elasticity: Finger pad Friction against Textured Surfaces","authors":"D.A. Sergachev , D.T.A. Matthews , E. van der Heide","doi":"10.1016/j.biotri.2019.100097","DOIUrl":"10.1016/j.biotri.2019.100097","url":null,"abstract":"<div>Surface topography significantly influences tactile friction and perception. While friction forces can be reduced by surface texturing, selection of pattern dimensions is challenging due to the highly variable elastic modulus of the skin. This work proposes an empirical approach for the evaluation of the skin elasticity through surface transition from asperity to full contact state. To highlight the contact transition, two textures with evenly distributed identical micro asperities, but varying density, were moulded with several grades of silicone rubber. Dynamic friction coefficient measurements were performed during finger pad sliding against the textured samples with a range of normal loads up to 5 N. A combination of analytical and numerical contact models is used to explain the observed friction behaviour, estimate the development of contact area and calculate the effective elastic modulus of the skin at the micro-scale. Low density textures clearly indicate the transition to the full contact state, which is reflected in friction coefficient development, while high density textures remain in an asperity contact state, with significantly lower friction values. The effective Young's modulus is hereby estimated in the range of 0.2–0.5 MPa. Observed frictional behaviour is explained by the change in the apparent and real contact areas. The presented approach allows to study the influence of individual surface parameters on effective skin elastic modulus, which is essential for the development of functional surfaces with improved tactile perception.</div>","PeriodicalId":38233,"journal":{"name":"Biotribology","volume":"18 ","pages":"Article 100097"},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.biotri.2019.100097","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44854388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Investigation of CoCrMo material loss in a novel bio-tribometer designed to study direct cell reaction to wear and corrosion products 用于研究细胞对磨损和腐蚀产物直接反应的新型生物摩擦计中CoCrMo材料损耗的研究

Biotribology Pub Date : 2019-06-01 DOI: 10.1016/j.biotri.2019.100090

Radice S., Holcomb T., Pourzal R., Hallab N.J., Laurent M.P., Wimmer M.A.

{"title":"Investigation of CoCrMo material loss in a novel bio-tribometer designed to study direct cell reaction to wear and corrosion products","authors":"Radice S., Holcomb T., Pourzal R., Hallab N.J., Laurent M.P., Wimmer M.A.","doi":"10.1016/j.biotri.2019.100090","DOIUrl":"10.1016/j.biotri.2019.100090","url":null,"abstract":"<div>Wear and corrosion in total hip replacement negatively impact implant service-life and patient well-being. The aim of this study was to generate a statistical response surface of material loss using an apparatus, capable of testing the effect of wear and corrosion products in situ on cells, such as macrophages. The test chamber of a ball-on-flat tribometer operating inside a CO2 incubator was integrated with an electrochemical setup and adapted for cell culture work. A 20-test series, following a 2-level 3-factor design of experiments, was performed with a ceramic head in reciprocating rotational motion against a CoCrMo-alloy disc, under constant load. The lubricant was cell culture medium (RPMI-1640 + 10 vol% bovine serum). Response surfaces were generated, which statistically showed the influence of motion amplitude, load, and potential on the total mass loss and wear scar volume of the metallic discs. Potential had the highest impact on the total mass loss, while motion amplitude and load significantly influenced the wear scar volume. The concentrations of the alloy elements found in the lubricants reflected the bulk-alloy stoichiometry. The total concentration of Co released into the lubricant (2.3–63 ppm by total mass loss, 1.5 to 62 ppm by ICP-MS) corresponded well with the known range to trigger cell response. Tribocorrosion tests in the presence of cells and tissues, such as macrophages, lymphocytes and/or synovium, will be carried out in the future.</div>","PeriodicalId":38233,"journal":{"name":"Biotribology","volume":"18 ","pages":"Article 100090"},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.biotri.2019.100090","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37151168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

WITHDRAWN: Review of metrology and tribological behavior in legless reptiles 撤回:无腿爬行动物的计量学和摩擦学行为综述

Biotribology Pub Date : 2015-12-02 DOI: 10.1016/J.BIOTRI.2015.11.002

H. Abdel-aal

引用次数: 0

Biotribology of Total Hip Replacement: The Metal‐on‐Metal Articulation 全髋关节置换术的生物摩擦学:金属对金属关节

Biotribology Pub Date : 2013-03-07 DOI: 10.1002/9781118557969.CH1

J. Kretzer

引用次数: 5

Predicting textural attributes and frictional characteristics of topical formulations based on non-linear rheology 预测基于非线性流变的局部配方的纹理属性和摩擦特性

Biotribology Pub Date : 1900-01-01 DOI: 10.1016/j.biotri.2023.100249

F. Cyriac, Tee Xin Yi, P. Chow